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Volumn 9, Issue 5, 2014, Pages

MicroRNA-7 inhibits tumor metastasis and reverses epithelial-mesenchymal transition through AKT/ERK1/2 inactivation by targeting EGFR in epithelial ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYTOKERATIN 18; EPIDERMAL GROWTH FACTOR RECEPTOR; MICRORNA; MICRORNA 7; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; SMALL INTERFERING RNA; TUMOR MARKER; UNCLASSIFIED DRUG; VIMENTIN; EGFR PROTEIN, HUMAN; MIRN7 MICRORNA, HUMAN;

EID: 84901245983     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096718     Document Type: Article
Times cited : (92)

References (45)
  • 3
    • 53049107572 scopus 로고    scopus 로고
    • hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells
    • Shi L, Cheng Z, Zhang J, Li R, Zhao P, et al. (2008) hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells. Brain Research 1236: 185-193.
    • (2008) Brain Research , vol.1236 , pp. 185-193
    • Shi, L.1    Cheng, Z.2    Zhang, J.3    Li, R.4    Zhao, P.5
  • 4
    • 70350724832 scopus 로고    scopus 로고
    • Identification of differentially expressed microRNAs by microarray: A possible role for microRNAs gene in medulloblastomas
    • Liu WG, Chao T, Peng X, Yuan J, Ma Z, et al. (2009) Identification of differentially expressed microRNAs by microarray: a possible role for microRNAs gene in medulloblastomas. Chinese Medical Journal.
    • (2009) Chinese Medical Journal
    • Liu, W.G.1    Chao, T.2    Peng, X.3    Yuan, J.4    Ma, Z.5
  • 5
    • 77957560959 scopus 로고    scopus 로고
    • MiR-339-5p inhibits breast cancer cell migration and invasion in vitro and may be a potential biomarker for breast cancer prognosis
    • Wu Z-s, Wu Q, Wang C-q, Wang X-n, Wang Y, et al. (2010) MiR-339-5p inhibits breast cancer cell migration and invasion in vitro and may be a potential biomarker for breast cancer prognosis. BMC Cancer 10: 542.
    • (2010) BMC Cancer , vol.10 , pp. 542
    • Wu, Z.-S.1    Wu, Q.2    Wang, C.-Q.3    Wang, X.-N.4    Wang, Y.5
  • 7
    • 79955146655 scopus 로고    scopus 로고
    • MicroRNA let-7f inhibits tumor invasion and metastasis by targeting MYH9 in human gastric cancer
    • Liang S, He L, Zhao X, Miao Y, Gu Y, et al. (2011) MicroRNA let-7f inhibits tumor invasion and metastasis by targeting MYH9 in human gastric cancer. PLoS One 6: e18409.
    • (2011) PLoS One , vol.6
    • Liang, S.1    He, L.2    Zhao, X.3    Miao, Y.4    Gu, Y.5
  • 8
    • 66049147178 scopus 로고    scopus 로고
    • MicroRNAs 373 and 520c are downregulated in prostate cancer, suppress CD44 translation and enhance invasion of prostate cancer cells in vitro
    • Yang K, Handorean AM, Iczkowski KA (2009) MicroRNAs 373 and 520c are downregulated in prostate cancer, suppress CD44 translation and enhance invasion of prostate cancer cells in vitro. Int J Clin Exp Pathol 2: 361-369.
    • (2009) Int J Clin Exp Pathol , vol.2 , pp. 361-369
    • Yang, K.1    Handorean, A.M.2    Iczkowski, K.A.3
  • 9
    • 84875226458 scopus 로고    scopus 로고
    • MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor
    • Zhao X, Dou W, He L, Liang S, Tie J, et al. (2012) MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. Oncogene.
    • (2012) Oncogene
    • Zhao, X.1    Dou, W.2    He, L.3    Liang, S.4    Tie, J.5
  • 10
    • 45549089973 scopus 로고    scopus 로고
    • microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is downregulated in glioblastoma
    • Kefas B, Godlewski J, Comeau L, Li Y, Abounader R, et al. (2008) microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is downregulated in glioblastoma. Cancer Res 68: 3566-3572.
    • (2008) Cancer Res , vol.68 , pp. 3566-3572
    • Kefas, B.1    Godlewski, J.2    Comeau, L.3    Li, Y.4    Abounader, R.5
  • 11
    • 79551527320 scopus 로고    scopus 로고
    • miRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways
    • Saydam O, Senol O, Wurdinger T, Mizrak A, Ozdener GB, et al. (2011) miRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways. Cancer Res 71: 852-861.
    • (2011) Cancer Res , vol.71 , pp. 852-861
    • Saydam, O.1    Senol, O.2    Wurdinger, T.3    Mizrak, A.4    Ozdener, G.B.5
  • 14
    • 84863625227 scopus 로고    scopus 로고
    • Suppression of the epidermal growth factor receptor inhibits epithelial-mesenchymal transition in human pancreatic cancer PANC-1 cells
    • Chang ZG, Wei JM, Qin CF, Hao K, Tian XD, et al. (2012) Suppression of the epidermal growth factor receptor inhibits epithelial-mesenchymal transition in human pancreatic cancer PANC-1 cells. Dig Dis Sci 57: 1181-1189.
    • (2012) Dig Dis Sci , vol.57 , pp. 1181-1189
    • Chang, Z.G.1    Wei, J.M.2    Qin, C.F.3    Hao, K.4    Tian, X.D.5
  • 15
    • 84865419430 scopus 로고    scopus 로고
    • Inhibition of EGFR-AKT Axis Results in the Suppression of Ovarian Tumors In Vitro and in Preclinical Mouse Model
    • Loganathan S, Kandala PK, Gupta P, Srivastava SK (2012) Inhibition of EGFR-AKT Axis Results in the Suppression of Ovarian Tumors In Vitro and in Preclinical Mouse Model. PLoS One 7: e43577.
    • (2012) PLoS One , vol.7
    • Loganathan, S.1    Kandala, P.K.2    Gupta, P.3    Srivastava, S.K.4
  • 16
    • 77956344288 scopus 로고    scopus 로고
    • Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells
    • Gan Y, Shi C, Inge L, Hibner M, Balducci J, et al. (2010) Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells. Oncogene 29: 4947-4958.
    • (2010) Oncogene , vol.29 , pp. 4947-4958
    • Gan, Y.1    Shi, C.2    Inge, L.3    Hibner, M.4    Balducci, J.5
  • 17
    • 65549120766 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7
    • Webster RJ, Giles KM, Price KJ, Zhang PM, Mattick JS, et al. (2009) Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7. J Biol Chem 284: 5731-5741.
    • (2009) J Biol Chem , vol.284 , pp. 5731-5741
    • Webster, R.J.1    Giles, K.M.2    Price, K.J.3    Zhang, P.M.4    Mattick, J.S.5
  • 18
    • 34248141386 scopus 로고    scopus 로고
    • Crosstalk between EGFR and TrkB enhances ovarian cancer cell migration and proliferation
    • Qiu L, Zhou C, Sun Y, Di W, Scheffler E, et al. (2006) Crosstalk between EGFR and TrkB enhances ovarian cancer cell migration and proliferation. Int J Oncol 29: 1003-1011.
    • (2006) Int J Oncol , vol.29 , pp. 1003-1011
    • Qiu, L.1    Zhou, C.2    Sun, Y.3    Di, W.4    Scheffler, E.5
  • 19
    • 33847263980 scopus 로고    scopus 로고
    • Inhibition of CD147 gene expression via RNA interference reduces tumor cell invasion, tumorigenicity and increases chemosensitivity to paclitaxel in HO-8910pm cells
    • DOI 10.1016/j.canlet.2006.07.005, PII S0304383506004794
    • Zou W, Yang H, Hou X, Zhang W, Chen B, et al. (2007) Inhibition of CD147 gene expression via RNA interference reduces tumor cell invasion, tumorigenicity and increases chemosensitivity to paclitaxel in HO-8910pm cells. Cancer Lett 248: 211-218. (Pubitemid 46330554)
    • (2007) Cancer Letters , vol.248 , Issue.2 , pp. 211-218
    • Zou, W.1    Yang, H.2    Hou, X.3    Zhang, W.4    Chen, B.5    Xin, X.6
  • 20
    • 33646037353 scopus 로고    scopus 로고
    • Suppression of human ovarian carcinoma metastasis by the metastasis-suppressor gene, BRMS1
    • Zhang S, Lin QD, Di W (2006) Suppression of human ovarian carcinoma metastasis by the metastasis-suppressor gene, BRMS1. Int J Gynecol Cancer 16: 522-531.
    • (2006) Int J Gynecol Cancer , vol.16 , pp. 522-531
    • Zhang, S.1    Lin, Q.D.2    Di, W.3
  • 22
    • 84859138356 scopus 로고    scopus 로고
    • EGF-induced EMT and invasiveness in serous borderline ovarian tumor cells: A possible step in the transition to low-grade serous carcinoma cells?
    • Cheng JC, Auersperg N, Leung PC (2012) EGF-induced EMT and invasiveness in serous borderline ovarian tumor cells: a possible step in the transition to low-grade serous carcinoma cells? PLoS One 7: e34071.
    • (2012) PLoS One , vol.7
    • Cheng, J.C.1    Auersperg, N.2    Leung, P.C.3
  • 24
    • 70349871321 scopus 로고    scopus 로고
    • MicroRNA expression, survival, and response to interferon in liver cancer
    • Ji J, Shi J, Budhu A, Yu Z, Forgues M, et al. (2009) MicroRNA expression, survival, and response to interferon in liver cancer. N Engl J Med 361: 1437-1447.
    • (2009) N Engl J Med , vol.361 , pp. 1437-1447
    • Ji, J.1    Shi, J.2    Budhu, A.3    Yu, Z.4    Forgues, M.5
  • 25
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • DOI 10.1016/0092-8674(93)90529-Y
    • Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854. (Pubitemid 24014542)
    • (1993) Cell , vol.75 , Issue.5 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 26
  • 27
    • 84862638243 scopus 로고    scopus 로고
    • Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN
    • Han M, Liu M, Wang Y, Chen X, Xu J, et al. (2012) Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN. PLoS One 7: e39520.
    • (2012) PLoS One , vol.7
    • Han, M.1    Liu, M.2    Wang, Y.3    Chen, X.4    Xu, J.5
  • 28
    • 84864422842 scopus 로고    scopus 로고
    • MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression
    • Kong X, Li G, Yuan Y, He Y, Wu X, et al. (2012) MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression. PLoS One 7: e41523.
    • (2012) PLoS One , vol.7
    • Kong, X.1    Li, G.2    Yuan, Y.3    He, Y.4    Wu, X.5
  • 29
    • 33845950849 scopus 로고    scopus 로고
    • Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cells
    • Zhou C, Qiu L, Sun Y, Healey S, Wanebo H, et al. (2006) Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cells. Int J Oncol 29: 269-278.
    • (2006) Int J Oncol , vol.29 , pp. 269-278
    • Zhou, C.1    Qiu, L.2    Sun, Y.3    Healey, S.4    Wanebo, H.5
  • 30
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP (2002) Epithelial-mesenchymal transitions in tumour progression. Nature Reviews Cancer 2: 442-454.
    • (2002) Nature Reviews Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 31
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • DOI 10.1038/nrm1835, PII NRM1835
    • Thiery JP, Sleeman JP (2006) Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7: 131-142. (Pubitemid 43278296)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 32
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 34
    • 84871345038 scopus 로고    scopus 로고
    • miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells
    • Hassan MQ, Maeda Y, Taipaleenmaki H, Zhang W, Jafferji M, et al. (2012) miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells. J Biol Chem.
    • (2012) J Biol Chem
    • Hassan, M.Q.1    Maeda, Y.2    Taipaleenmaki, H.3    Zhang, W.4    Jafferji, M.5
  • 36
    • 76749152907 scopus 로고    scopus 로고
    • miR-146a Suppresses Invasion of Pancreatic Cancer Cells
    • Li Y, VandenBoom TG, Wang Z, Kong D, Ali S, et al. (2010) miR-146a Suppresses Invasion of Pancreatic Cancer Cells. Cancer Research 70: 1486-1495.
    • (2010) Cancer Research , vol.70 , pp. 1486-1495
    • Li, Y.1    VandenBoom, T.G.2    Wang, Z.3    Kong, D.4    Ali, S.5
  • 37
    • 55849123946 scopus 로고    scopus 로고
    • MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA
    • Kong W, Yang H, He L, Zhao JJ, Coppola D, et al. (2008) MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA. Mol Cell Biol 28: 6773-6784.
    • (2008) Mol Cell Biol , vol.28 , pp. 6773-6784
    • Kong, W.1    Yang, H.2    He, L.3    Zhao, J.J.4    Coppola, D.5
  • 38
    • 64049107465 scopus 로고    scopus 로고
    • miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis
    • Gebeshuber CA, Zatloukal K, Martinez J (2009) miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis. EMBO Rep 10: 400-405.
    • (2009) EMBO Rep , vol.10 , pp. 400-405
    • Gebeshuber, C.A.1    Zatloukal, K.2    Martinez, J.3
  • 39
    • 33644643243 scopus 로고    scopus 로고
    • Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death
    • Qiu L, Di W, Jiang Q, Scheffler E, Derby S, et al. (2005) Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death. Int J Oncol 27: 1441-1448.
    • (2005) Int J Oncol , vol.27 , pp. 1441-1448
    • Qiu, L.1    Di, W.2    Jiang, Q.3    Scheffler, E.4    Derby, S.5
  • 40
    • 84867221976 scopus 로고    scopus 로고
    • PEGylated liposome IHL-305 markedly improved the survival of ovarian cancer peritoneal metastasis in mouse
    • Konishi H, Takagi A, Kurita A, Kaneda N, Matsuzaki T (2012) PEGylated liposome IHL-305 markedly improved the survival of ovarian cancer peritoneal metastasis in mouse. BMC Cancer 12: 462.
    • (2012) BMC Cancer , vol.12 , pp. 462
    • Konishi, H.1    Takagi, A.2    Kurita, A.3    Kaneda, N.4    Matsuzaki, T.5
  • 42
    • 49749116834 scopus 로고    scopus 로고
    • Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells
    • Ji C, Cao C, Lu S, Kivlin R, Amaral A, et al. (2008) Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells. Cancer Chemother Pharmacol 62: 857-865.
    • (2008) Cancer Chemother Pharmacol , vol.62 , pp. 857-865
    • Ji, C.1    Cao, C.2    Lu, S.3    Kivlin, R.4    Amaral, A.5
  • 43
    • 67049164999 scopus 로고    scopus 로고
    • Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug
    • Saegusa M, Hashimura M, Kuwata T, Okayasu I (2009) Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug. Am J Pathol 174: 2107-2115.
    • (2009) Am J Pathol , vol.174 , pp. 2107-2115
    • Saegusa, M.1    Hashimura, M.2    Kuwata, T.3    Okayasu, I.4
  • 44
    • 45149125149 scopus 로고    scopus 로고
    • Mesenchymal transition in kidney collecting duct epithelial cells
    • Ivanova L, Butt MJ, Matsell DG (2008) Mesenchymal transition in kidney collecting duct epithelial cells. Am J Physiol Renal Physiol 294: F1238-1248.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Ivanova, L.1    Butt, M.J.2    Matsell, D.G.3
  • 45
    • 84861409108 scopus 로고    scopus 로고
    • Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells
    • Wang Y, Sheng Q, Spillman MA, Behbakht K, Gu H (2012) Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells. Oncogene 31: 2512-2520.
    • (2012) Oncogene , vol.31 , pp. 2512-2520
    • Wang, Y.1    Sheng, Q.2    Spillman, M.A.3    Behbakht, K.4    Gu, H.5


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