메뉴 건너뛰기




Volumn 30, Issue 4, 2013, Pages 1976-1984

Epigenetic silencing of miR-126 contributes to tumor invasion and angiogenesis in colorectal cancer

Author keywords

Colorectal cancer; Invasion; Methylation; MiR 126; Tumor angiogenesis

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; MICRORNA 126; VASCULOTROPIN;

EID: 84882686726     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2633     Document Type: Article
Times cited : (99)

References (45)
  • 2
    • 0037264812 scopus 로고    scopus 로고
    • Metastasis suppressors alter the signal transduction of cancer cells
    • Steeg PS: Metastasis suppressors alter the signal transduction of cancer cells. Nat Rev Cancer 3: 55-63, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 55-63
    • Steeg, P.S.1
  • 3
    • 61849137222 scopus 로고    scopus 로고
    • Many roads to maturity: MicroRNA biogenesis pathways and their regulation
    • Winter J, Jung S, Keller S, Gregory RI and Diederichs S: Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol 11: 228-234, 2009.
    • (2009) Nat Cell Biol , vol.11 , pp. 228-234
    • Winter, J.1    Jung, S.2    Keller, S.3    Gregory, R.I.4    Diederichs, S.5
  • 4
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - MicroRNAs with a role in cancer
    • Esquela-Kerscher A and Slack FJ: Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 6: 259-269, 2006.
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 5
    • 40349094597 scopus 로고    scopus 로고
    • MicroRNA- 373 induces expression of genes with complementary promoter sequences
    • Place RF, Li LC, Pookot D, Noonan EJ and Dahiya R: MicroRNA- 373 induces expression of genes with complementary promoter sequences. Proc Natl Acad Sci USA 105: 1608-1613, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 1608-1613
    • Place, R.F.1    Li, L.C.2    Pookot, D.3    Noonan, E.J.4    Dahiya, R.5
  • 7
    • 33749504736 scopus 로고    scopus 로고
    • MicroRNAs and the hallmarks of cancer
    • Dalmay T and Edwards DR: MicroRNAs and the hallmarks of cancer. Oncogene 25: 6170-6175, 2006.
    • (2006) Oncogene , vol.25 , pp. 6170-6175
    • Dalmay, T.1    Edwards, D.R.2
  • 17
    • 79551511687 scopus 로고    scopus 로고
    • MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis
    • Otsubo T, Akiyama Y, Hashimoto Y, Shimada S, Goto K and Yuasa Y: MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis. PLoS One 6: e16617, 2011.
    • (2011) PLoS One , vol.6
    • Otsubo, T.1    Akiyama, Y.2    Hashimoto, Y.3    Shimada, S.4    Goto, K.5    Yuasa, Y.6
  • 19
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target
    • Ferrara N and Kerbel RS: Angiogenesis as a therapeutic target. Nature 438: 967-974, 2005.
    • (2005) Nature , vol.438 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 20
    • 70450175957 scopus 로고    scopus 로고
    • Targeting angiogenesis: Progress with anti-VEGF treatment with large molecules
    • Grothey A and Galanis E: Targeting angiogenesis: progress with anti-VEGF treatment with large molecules. Nat Rev Clin Oncol 6: 507-518, 2009.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 507-518
    • Grothey, A.1    Galanis, E.2
  • 21
    • 84655175072 scopus 로고    scopus 로고
    • Down-regulation of miR-126 expression in colorectal cancer and its clinical significance
    • Li XM, Wang AM, Zhang J and Yi H: Down-regulation of miR-126 expression in colorectal cancer and its clinical significance. Med Oncol 28: 1054-1057, 2011.
    • (2011) Med Oncol , vol.28 , pp. 1054-1057
    • Li, X.M.1    Wang, A.M.2    Zhang, J.3    Yi, H.4
  • 22
    • 58549108465 scopus 로고    scopus 로고
    • Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells
    • Saito Y, Friedman JM, Chihara Y, Egger G, Chuang JC and Liang G: Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells. Biochem Biophys Res Commun 379: 726-731, 2009.
    • (2009) Biochem Biophys Res Commun , vol.379 , pp. 726-731
    • Saito, Y.1    Friedman, J.M.2    Chihara, Y.3    Egger, G.4    Chuang, J.C.5    Liang, G.6
  • 25
    • 33748928159 scopus 로고    scopus 로고
    • The diverse functions of microRNAs in animal development and disease
    • Kloosterman WP and Plasterk RH: The diverse functions of microRNAs in animal development and disease. Dev Cell 11: 441-450, 2006.
    • (2006) Dev Cell , vol.11 , pp. 441-450
    • Kloosterman, W.P.1    Plasterk, R.H.2
  • 26
    • 81255188940 scopus 로고    scopus 로고
    • Tumor angiogenesis: Molecular pathways and therapeutic targets
    • Weis SM and Cheresh DA: Tumor angiogenesis: molecular pathways and therapeutic targets. Nat Med 17: 1359-1370, 2011.
    • (2011) Nat Med , vol.17 , pp. 1359-1370
    • Weis, S.M.1    Cheresh, D.A.2
  • 28
    • 80655125015 scopus 로고    scopus 로고
    • MicroRNA-21 regulates the metastatic behavior of B16 melanoma cells
    • Yang CH, Yue J, Pfeffer SR, Handorf CR and Pfeffer LM: MicroRNA-21 regulates the metastatic behavior of B16 melanoma cells. J Biol Chem 286: 39172-39178, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 39172-39178
    • Yang, C.H.1    Yue, J.2    Pfeffer, S.R.3    Handorf, C.R.4    Pfeffer, L.M.5
  • 29
    • 80055047968 scopus 로고    scopus 로고
    • MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression
    • Fang JH, Zhou HC, Zeng C, Yang J, Liu Y, Huang X, Zhang JP, Guan XY and Zhuang SM: MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression. Hepatology 54: 1729-1740, 2011.
    • (2011) Hepatology , vol.54 , pp. 1729-1740
    • Fang, J.H.1    Zhou, H.C.2    Zeng, C.3    Yang, J.4    Liu, Y.5    Huang, X.6    Zhang, J.P.7    Guan, X.Y.8    Zhuang, S.M.9
  • 30
    • 84858336969 scopus 로고    scopus 로고
    • MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1
    • Xu Y, Zhao F, Wang Z, Song Y, Luo Y, Zhang X, Jiang L, Sun Z, Miao Z and Xu H: MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1. Oncogene 31: 1398-1407, 2012.
    • (2012) Oncogene , vol.31 , pp. 1398-1407
    • Xu, Y.1    Zhao, F.2    Wang, Z.3    Song, Y.4    Luo, Y.5    Zhang, X.6    Jiang, L.7    Sun, Z.8    Miao, Z.9    Xu, H.10
  • 31
    • 68649114571 scopus 로고    scopus 로고
    • AngiomiRs - Key regulators of angiogenesis
    • Wang S and Olson EN: AngiomiRs - key regulators of angiogenesis. Curr Opin Genet Dev 19: 205-211, 2009.
    • (2009) Curr Opin Genet Dev , vol.19 , pp. 205-211
    • Wang, S.1    Olson, E.N.2
  • 32
    • 84855813448 scopus 로고    scopus 로고
    • A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells
    • Png KJ, Halberg N, Yoshida M and Tavazoie SF: A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells. Nature 481: 190-194, 2011.
    • (2011) Nature , vol.481 , pp. 190-194
    • Png, K.J.1    Halberg, N.2    Yoshida, M.3    Tavazoie, S.F.4
  • 33
    • 84861878901 scopus 로고    scopus 로고
    • MiR-126 enhances the sensitivity of non-small cell lung cancer cells to anticancer agents by targeting vascular endothelial growth factor A
    • Zhu X, Li H, Long L, Hui L, Chen H, Wang X, Shen H and Xu W: miR-126 enhances the sensitivity of non-small cell lung cancer cells to anticancer agents by targeting vascular endothelial growth factor A. Acta Biochim Biophys Sin 44: 519-526, 2012.
    • (2012) Acta Biochim Biophys Sin , vol.44 , pp. 519-526
    • Zhu, X.1    Li, H.2    Long, L.3    Hui, L.4    Chen, H.5    Wang, X.6    Shen, H.7    Xu, W.8
  • 36
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M: Epigenetics in cancer. N Engl J Med 358: 1148-1159, 2008.
    • (2008) N Engl J Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 38
    • 49249121155 scopus 로고    scopus 로고
    • Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
    • Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y and Tokino T: Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res 68: 4123-4132, 2008.
    • (2008) Cancer Res , vol.68 , pp. 4123-4132
    • Toyota, M.1    Suzuki, H.2    Sasaki, Y.3    Maruyama, R.4    Imai, K.5    Shinomura, Y.6    Tokino, T.7
  • 40
    • 33749598345 scopus 로고    scopus 로고
    • Epigenetic activation of tumor suppressor microRNAs in human cancer cells
    • Saito Y and Jones PA: Epigenetic activation of tumor suppressor microRNAs in human cancer cells. Cell Cycle 5: 2220-2222, 2006.
    • (2006) Cell Cycle , vol.5 , pp. 2220-2222
    • Saito, Y.1    Jones, P.A.2
  • 41
    • 63049090100 scopus 로고    scopus 로고
    • Metastasis: From dissemination to organ-specific colonization
    • Nguyen DX, Bos PD and Massagué J: Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer 9: 274-284, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 274-284
    • Nguyen, D.X.1    Bos, P.D.2    Massagué, J.3
  • 42
    • 70350233470 scopus 로고    scopus 로고
    • Metastamir: The field of metastasis-regulatory microRNA is spreading
    • Hurst DR, Edmonds MD and Welch DR: Metastamir: the field of metastasis-regulatory microRNA is spreading. Cancer Res 69: 7495-7498, 2009.
    • (2009) Cancer Res , vol.69 , pp. 7495-7498
    • Hurst, D.R.1    Edmonds, M.D.2    Welch, D.R.3
  • 44
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani IA, Rasheed SA, Nikolova SA, Leupold JH, Colburn NH, Post S and Allgayer H: MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27: 2128-2136, 2008.
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, S.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6    Allgayer, H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.