메뉴 건너뛰기




Volumn 12, Issue 1, 2013, Pages

A TrkB-STAT3-miR-204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cells

Author keywords

Endometrial carcinoma; Invasion; miR 204 5p; Prognosis; Proliferation; Regulatory circuitry; STAT3; TrkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MICRORNA; MICRORNA 204 5P; STAT3 PROTEIN; UNCLASSIFIED DRUG;

EID: 84889766586     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-12-155     Document Type: Article
Times cited : (118)

References (56)
  • 1
    • 84872967522 scopus 로고    scopus 로고
    • Cancer statistics, 2013
    • 10.3322/caac.21166, 23335087
    • Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin 2013, 63:11-30. 10.3322/caac.21166, 23335087.
    • (2013) CA Cancer J Clin , vol.63 , pp. 11-30
    • Siegel, R.1    Naishadham, D.2    Jemal, A.3
  • 3
    • 0020660717 scopus 로고
    • Two pathogenetic types of endometrial carcinoma
    • 10.1016/0090-8258(83)90111-7, 6822361
    • Bokhman JV. Two pathogenetic types of endometrial carcinoma. Gynecol Oncol 1983, 15:10-17. 10.1016/0090-8258(83)90111-7, 6822361.
    • (1983) Gynecol Oncol , vol.15 , pp. 10-17
    • Bokhman, J.V.1
  • 4
    • 84865687920 scopus 로고    scopus 로고
    • The dualistic model of endometrial cancer: the challenge of classifying grade 3 endometrioid carcinoma
    • 10.1016/j.ygyno.2011.09.036, 22014629
    • Zannoni GF, Scambia G, Gallo D. The dualistic model of endometrial cancer: the challenge of classifying grade 3 endometrioid carcinoma. Gynecol Oncol 2012, 127:262-263. 10.1016/j.ygyno.2011.09.036, 22014629.
    • (2012) Gynecol Oncol , vol.127 , pp. 262-263
    • Zannoni, G.F.1    Scambia, G.2    Gallo, D.3
  • 5
    • 84867186124 scopus 로고    scopus 로고
    • Risk factors for recurrence amongst high intermediate risk patients with endometrioid adenocarcinoma
    • 10.3802/jgo.2012.23.4.257, 3469861, 23094129
    • Bahng AY, Chu C, Wileyto P, Rubin S, Lin LL. Risk factors for recurrence amongst high intermediate risk patients with endometrioid adenocarcinoma. J Gynecol Oncol 2012, 23:257-264. 10.3802/jgo.2012.23.4.257, 3469861, 23094129.
    • (2012) J Gynecol Oncol , vol.23 , pp. 257-264
    • Bahng, A.Y.1    Chu, C.2    Wileyto, P.3    Rubin, S.4    Lin, L.L.5
  • 7
    • 79955509427 scopus 로고    scopus 로고
    • Role and relevance of TrkB mutations and expression in non-small cell lung cancer
    • 10.1158/1078-0432.CCR-10-3034, 3086954, 21242122
    • Harada T, Yatabe Y, Takeshita M, Koga T, Yano T, Wang Y, Giaccone G. Role and relevance of TrkB mutations and expression in non-small cell lung cancer. Clin Cancer Res 2011, 17:2638-2645. 10.1158/1078-0432.CCR-10-3034, 3086954, 21242122.
    • (2011) Clin Cancer Res , vol.17 , pp. 2638-2645
    • Harada, T.1    Yatabe, Y.2    Takeshita, M.3    Koga, T.4    Yano, T.5    Wang, Y.6    Giaccone, G.7
  • 8
    • 79953300722 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and neurotrophin-4/5 are expressed in breast cancer and can be targeted to inhibit tumor cell survival
    • 10.1158/1078-0432.CCR-10-1890, 21350004
    • Vanhecke E, Adriaenssens E, Verbeke S, Meignan S, Germain E, Berteaux N, Nurcombe V, Le Bourhis X, Hondermarck H. Brain-derived neurotrophic factor and neurotrophin-4/5 are expressed in breast cancer and can be targeted to inhibit tumor cell survival. Clin Cancer Res 2011, 17:1741-1752. 10.1158/1078-0432.CCR-10-1890, 21350004.
    • (2011) Clin Cancer Res , vol.17 , pp. 1741-1752
    • Vanhecke, E.1    Adriaenssens, E.2    Verbeke, S.3    Meignan, S.4    Germain, E.5    Berteaux, N.6    Nurcombe, V.7    Le Bourhis, X.8    Hondermarck, H.9
  • 9
    • 84880840836 scopus 로고    scopus 로고
    • Upregulation of TrkB Promotes Epithelial-Mesenchymal Transition and Anoikis Resistance in Endometrial Carcinoma
    • 10.1371/journal.pone.0070616, 3728299, 23936232
    • Bao W, Qiu H, Yang T, Luo X, Zhang H, Wan X. Upregulation of TrkB Promotes Epithelial-Mesenchymal Transition and Anoikis Resistance in Endometrial Carcinoma. PloS one 2013, 8:e70616. 10.1371/journal.pone.0070616, 3728299, 23936232.
    • (2013) PloS one , vol.8
    • Bao, W.1    Qiu, H.2    Yang, T.3    Luo, X.4    Zhang, H.5    Wan, X.6
  • 10
    • 4344627055 scopus 로고    scopus 로고
    • Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB
    • 10.1038/nature02765, 15329723
    • Douma S, Van Laar T, Zevenhoven J, Meuwissen R, Van Garderen E, Peeper DS. Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB. Nature 2004, 430:1034-1039. 10.1038/nature02765, 15329723.
    • (2004) Nature , vol.430 , pp. 1034-1039
    • Douma, S.1    Van Laar, T.2    Zevenhoven, J.3    Meuwissen, R.4    Van Garderen, E.5    Peeper, D.S.6
  • 12
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • 10.1016/S0092-8674(04)00045-5, 14744438
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297. 10.1016/S0092-8674(04)00045-5, 14744438.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 16
    • 34547555796 scopus 로고    scopus 로고
    • Global and local architecture of the mammalian microRNA-transcription factor regulatory network
    • 10.1371/journal.pcbi.0030131, 1914371, 17630826
    • Shalgi R, Lieber D, Oren M, Pilpel Y. Global and local architecture of the mammalian microRNA-transcription factor regulatory network. PLoS Comput Biol 2007, 3:e131. 10.1371/journal.pcbi.0030131, 1914371, 17630826.
    • (2007) PLoS Comput Biol , vol.3
    • Shalgi, R.1    Lieber, D.2    Oren, M.3    Pilpel, Y.4
  • 18
    • 58149213891 scopus 로고    scopus 로고
    • Expression profile of mammalian microRNAs in endometrioid adenocarcinoma
    • 10.1097/CEJ.0b013e328305a07a, 19077565
    • Wu W, Lin Z, Zhuang Z, Liang X. Expression profile of mammalian microRNAs in endometrioid adenocarcinoma. Eur J Cancer Prev 2009, 18:50-55. 10.1097/CEJ.0b013e328305a07a, 19077565.
    • (2009) Eur J Cancer Prev , vol.18 , pp. 50-55
    • Wu, W.1    Lin, Z.2    Zhuang, Z.3    Liang, X.4
  • 19
    • 84155168994 scopus 로고    scopus 로고
    • Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1
    • 10.1002/ijc.26060, 21400511
    • Chung TK, Lau TS, Cheung TH, Yim SF, Lo KW, Siu NS, Chan LK, Yu MY, Kwong J, Doran G, et al. Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1. Int J Cancer 2012, 130:1036-1045. 10.1002/ijc.26060, 21400511.
    • (2012) Int J Cancer , vol.130 , pp. 1036-1045
    • Chung, T.K.1    Lau, T.S.2    Cheung, T.H.3    Yim, S.F.4    Lo, K.W.5    Siu, N.S.6    Chan, L.K.7    Yu, M.Y.8    Kwong, J.9    Doran, G.10
  • 21
    • 19344367302 scopus 로고    scopus 로고
    • A neurotrophin axis in myeloma: TrkB and BDNF promote tumor-cell survival
    • 10.1182/blood-2004-08-3096, 15657181
    • Pearse RN, Swendeman SL, Li Y, Rafii D, Hempstead BL. A neurotrophin axis in myeloma: TrkB and BDNF promote tumor-cell survival. Blood 2005, 105:4429-4436. 10.1182/blood-2004-08-3096, 15657181.
    • (2005) Blood , vol.105 , pp. 4429-4436
    • Pearse, R.N.1    Swendeman, S.L.2    Li, Y.3    Rafii, D.4    Hempstead, B.L.5
  • 24
    • 70349659954 scopus 로고    scopus 로고
    • On Trk-the TrkB signal transduction pathway is an increasingly important target in cancer biology
    • 10.1158/1078-0432.CCR-08-0651, 2756331, 19755385
    • Thiele CJ, Li Z, McKee AE. On Trk-the TrkB signal transduction pathway is an increasingly important target in cancer biology. Clin Cancer Res 2009, 15:5962-5967. 10.1158/1078-0432.CCR-08-0651, 2756331, 19755385.
    • (2009) Clin Cancer Res , vol.15 , pp. 5962-5967
    • Thiele, C.J.1    Li, Z.2    McKee, A.E.3
  • 25
    • 67650045932 scopus 로고    scopus 로고
    • A Twist-Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis
    • 10.1128/MCB.01164-08, 2698746, 19414595
    • Smit MA, Geiger TR, Song JY, Gitelman I, Peeper DS. A Twist-Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis. Mol Cell Biol 2009, 29:3722-3737. 10.1128/MCB.01164-08, 2698746, 19414595.
    • (2009) Mol Cell Biol , vol.29 , pp. 3722-3737
    • Smit, M.A.1    Geiger, T.R.2    Song, J.Y.3    Gitelman, I.4    Peeper, D.S.5
  • 26
    • 80052285316 scopus 로고    scopus 로고
    • Zeb1 is required for TrkB-induced epithelial-mesenchymal transition, anoikis resistance and metastasis
    • 10.1038/onc.2011.96, 21478908
    • Smit MA, Peeper DS. Zeb1 is required for TrkB-induced epithelial-mesenchymal transition, anoikis resistance and metastasis. Oncogene 2011, 30:3735-3744. 10.1038/onc.2011.96, 21478908.
    • (2011) Oncogene , vol.30 , pp. 3735-3744
    • Smit, M.A.1    Peeper, D.S.2
  • 29
    • 76149122103 scopus 로고    scopus 로고
    • Overexpression of TrkB promotes the progression of colon cancer
    • 10.1111/j.1600-0463.2009.02577.x, 20132184
    • Yu Y, Zhang S, Wang X, Yang Z, Ou G. Overexpression of TrkB promotes the progression of colon cancer. APMIS 2010, 118:188-195. 10.1111/j.1600-0463.2009.02577.x, 20132184.
    • (2010) APMIS , vol.118 , pp. 188-195
    • Yu, Y.1    Zhang, S.2    Wang, X.3    Yang, Z.4    Ou, G.5
  • 31
    • 38949109297 scopus 로고    scopus 로고
    • Suppression of anoikis by the neurotrophic receptor TrkB in human ovarian cancer
    • 10.1111/j.1349-7006.2007.00722.x, 18201274
    • Yu X, Liu L, Cai B, He Y, Wan X. Suppression of anoikis by the neurotrophic receptor TrkB in human ovarian cancer. Cancer Sci 2008, 99:543-552. 10.1111/j.1349-7006.2007.00722.x, 18201274.
    • (2008) Cancer Sci , vol.99 , pp. 543-552
    • Yu, X.1    Liu, L.2    Cai, B.3    He, Y.4    Wan, X.5
  • 32
    • 74049141478 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • 10.1093/carcin/bgp220, 2802667, 19752007
    • Sharma S, Kelly TK, Jones PA. Epigenetics in cancer. Carcinogenesis 2010, 31:27-36. 10.1093/carcin/bgp220, 2802667, 19752007.
    • (2010) Carcinogenesis , vol.31 , pp. 27-36
    • Sharma, S.1    Kelly, T.K.2    Jones, P.A.3
  • 34
    • 60549101101 scopus 로고    scopus 로고
    • Dysregulated microRNAs and their predicted targets associated with endometrioid endometrial adenocarcinoma in Hong Kong women
    • 10.1002/ijc.24071, 19065659
    • Chung TK, Cheung TH, Huen NY, Wong KW, Lo KW, Yim SF, Siu NS, Wong YM, Tsang PT, Pang MW, et al. Dysregulated microRNAs and their predicted targets associated with endometrioid endometrial adenocarcinoma in Hong Kong women. Int J Cancer 2009, 124:1358-1365. 10.1002/ijc.24071, 19065659.
    • (2009) Int J Cancer , vol.124 , pp. 1358-1365
    • Chung, T.K.1    Cheung, T.H.2    Huen, N.Y.3    Wong, K.W.4    Lo, K.W.5    Yim, S.F.6    Siu, N.S.7    Wong, Y.M.8    Tsang, P.T.9    Pang, M.W.10
  • 35
    • 77953089193 scopus 로고    scopus 로고
    • RNA interference: MicroRNAs as biomarkers
    • Baker M. RNA interference: MicroRNAs as biomarkers. Nature 2010, 464:1227.
    • (2010) Nature , vol.464 , pp. 1227
    • Baker, M.1
  • 36
    • 84871377399 scopus 로고    scopus 로고
    • Genomic loss of tumor suppressor miRNA-204 promotes cancer cell migration and invasion by activating AKT/mTOR/Rac1 signaling and actin reorganization
    • 10.1371/journal.pone.0052397, 3528651, 23285024
    • Imam JS, Plyler JR, Bansal H, Prajapati S, Bansal S, Rebeles J, Chen HI, Chang YF, Panneerdoss S, Zoghi B, et al. Genomic loss of tumor suppressor miRNA-204 promotes cancer cell migration and invasion by activating AKT/mTOR/Rac1 signaling and actin reorganization. PLoS One 2012, 7:e52397. 10.1371/journal.pone.0052397, 3528651, 23285024.
    • (2012) PLoS One , vol.7
    • Imam, J.S.1    Plyler, J.R.2    Bansal, H.3    Prajapati, S.4    Bansal, S.5    Rebeles, J.6    Chen, H.I.7    Chang, Y.F.8    Panneerdoss, S.9    Zoghi, B.10
  • 38
    • 84864674258 scopus 로고    scopus 로고
    • MicroRNA-204 critically regulates carcinogenesis in malignant peripheral nerve sheath tumors
    • Gong M, Ma J, Li M, Zhou M, Hock JM, Yu X. MicroRNA-204 critically regulates carcinogenesis in malignant peripheral nerve sheath tumors. Neurooncol 2012, 14:1007-1017.
    • (2012) Neurooncol , vol.14 , pp. 1007-1017
    • Gong, M.1    Ma, J.2    Li, M.3    Zhou, M.4    Hock, J.M.5    Yu, X.6
  • 39
    • 84863602818 scopus 로고    scopus 로고
    • Interleukin 11 regulates endometrial cancer cell adhesion and migration via STAT3
    • Lay V, Yap J, Sonderegger S, Dimitriadis E. Interleukin 11 regulates endometrial cancer cell adhesion and migration via STAT3. Int J Oncol 2012, 41:759-764.
    • (2012) Int J Oncol , vol.41 , pp. 759-764
    • Lay, V.1    Yap, J.2    Sonderegger, S.3    Dimitriadis, E.4
  • 40
    • 84883439228 scopus 로고    scopus 로고
    • A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth
    • 10.1002/emmm.201302507, 3799489, 23857777
    • Zhang Y, Yang J, Cui X, Chen Y, Zhu VF, Hagan JP, Wang H, Yu X, Hodges SE, Fang J, et al. A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth. EMBO Mol Med 2013, 5:1322-1334. 10.1002/emmm.201302507, 3799489, 23857777.
    • (2013) EMBO Mol Med , vol.5 , pp. 1322-1334
    • Zhang, Y.1    Yang, J.2    Cui, X.3    Chen, Y.4    Zhu, V.F.5    Hagan, J.P.6    Wang, H.7    Yu, X.8    Hodges, S.E.9    Fang, J.10
  • 42
    • 84878318949 scopus 로고    scopus 로고
    • Identification of four serum microRNAs from a genome-wide serum microRNA expression profile as potential non-invasive biomarkers for endometrioid endometrial cancer
    • 3742699, 23946815
    • Jia W, Wu Y, Zhang Q, Gao G, Zhang C, Xiang Y. Identification of four serum microRNAs from a genome-wide serum microRNA expression profile as potential non-invasive biomarkers for endometrioid endometrial cancer. Oncol Lett 2013, 6:261-267. 3742699, 23946815.
    • (2013) Oncol Lett , vol.6 , pp. 261-267
    • Jia, W.1    Wu, Y.2    Zhang, Q.3    Gao, G.4    Zhang, C.5    Xiang, Y.6
  • 44
  • 45
    • 77149136767 scopus 로고    scopus 로고
    • MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation
    • 2837600, 20039258
    • Huang J, Zhao L, Xing L, Chen D. MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation. Stem Cells 2010, 28:357-364. 2837600, 20039258.
    • (2010) Stem Cells , vol.28 , pp. 357-364
    • Huang, J.1    Zhao, L.2    Xing, L.3    Chen, D.4
  • 46
    • 78650843340 scopus 로고    scopus 로고
    • MiRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues
    • 2933889, 20634564
    • Saunders LR, Sharma AD, Tawney J, Nakagawa M, Okita K, Yamanaka S, Willenbring H, Verdin E. miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues. Aging 2010, 2:415-431. 2933889, 20634564.
    • (2010) Aging , vol.2 , pp. 415-431
    • Saunders, L.R.1    Sharma, A.D.2    Tawney, J.3    Nakagawa, M.4    Okita, K.5    Yamanaka, S.6    Willenbring, H.7    Verdin, E.8
  • 47
    • 84883645042 scopus 로고    scopus 로고
    • MiR-204 mediated loss of Myeloid cell leukemia-1 results in pancreatic cancer cell death
    • 10.1186/1476-4598-12-105, 3848798, 24025188
    • Chen Z, Sangwan V, Banerjee S, Mackenzie T, Dudeja V, Li X, Wang H, Vickers SM, Saluja AK. miR-204 mediated loss of Myeloid cell leukemia-1 results in pancreatic cancer cell death. Mol Cancer 2013, 12:105. 10.1186/1476-4598-12-105, 3848798, 24025188.
    • (2013) Mol Cancer , vol.12 , pp. 105
    • Chen, Z.1    Sangwan, V.2    Banerjee, S.3    Mackenzie, T.4    Dudeja, V.5    Li, X.6    Wang, H.7    Vickers, S.M.8    Saluja, A.K.9
  • 48
    • 84865861738 scopus 로고    scopus 로고
    • MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome
    • 10.1038/bjc.2012.356, 3464768, 22892391
    • Ryan J, Tivnan A, Fay J, Bryan K, Meehan M, Creevey L, Lynch J, Bray IM, O'Meara A, Davidoff AM, Stallings RL. MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome. Br J Cancer 2012, 107:967-976. 10.1038/bjc.2012.356, 3464768, 22892391.
    • (2012) Br J Cancer , vol.107 , pp. 967-976
    • Ryan, J.1    Tivnan, A.2    Fay, J.3    Bryan, K.4    Meehan, M.5    Creevey, L.6    Lynch, J.7    Bray, I.M.8    O'Meara, A.9    Davidoff, A.M.10    Stallings, R.L.11
  • 49
    • 84873089670 scopus 로고    scopus 로고
    • Diagnostic and prognostic significance of miRNA signatures in tissues and plasma of endometrioid endometrial carcinoma patients
    • 10.1002/ijc.27840, 22987275
    • Torres A, Torres K, Pesci A, Ceccaroni M, Paszkowski T, Cassandrini P, Zamboni G, Maciejewski R. Diagnostic and prognostic significance of miRNA signatures in tissues and plasma of endometrioid endometrial carcinoma patients. Int J Cancer 2013, 132:1633-1645. 10.1002/ijc.27840, 22987275.
    • (2013) Int J Cancer , vol.132 , pp. 1633-1645
    • Torres, A.1    Torres, K.2    Pesci, A.3    Ceccaroni, M.4    Paszkowski, T.5    Cassandrini, P.6    Zamboni, G.7    Maciejewski, R.8
  • 50
    • 79955102595 scopus 로고    scopus 로고
    • Targets of miR-200c mediate suppression of cell motility and anoikis resistance
    • 10.1186/bcr2867, 3219208, 21501518
    • Howe EN, Cochrane DR, Richer JK. Targets of miR-200c mediate suppression of cell motility and anoikis resistance. Breast Cancer Res 2011, 13:R45. 10.1186/bcr2867, 3219208, 21501518.
    • (2011) Breast Cancer Res , vol.13
    • Howe, E.N.1    Cochrane, D.R.2    Richer, J.K.3
  • 51
    • 84859720222 scopus 로고    scopus 로고
    • A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition
    • 10.1371/journal.pone.0035440, 3325969, 22514743
    • Moes M, Le Bechec A, Crespo I, Laurini C, Halavatyi A, Vetter G, Del Sol A, Friederich E. A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition. PLoS One 2012, 7:e35440. 10.1371/journal.pone.0035440, 3325969, 22514743.
    • (2012) PLoS One , vol.7
    • Moes, M.1    Le Bechec, A.2    Crespo, I.3    Laurini, C.4    Halavatyi, A.5    Vetter, G.6    Del Sol, A.7    Friederich, E.8
  • 52
    • 64049100937 scopus 로고    scopus 로고
    • Revised FIGO staging for carcinoma of the endometrium
    • 10.1016/j.ijgo.2009.02.010, 19345353
    • Creasman W. Revised FIGO staging for carcinoma of the endometrium. Int J Gynaecol Obstet 2009, 105:109. 10.1016/j.ijgo.2009.02.010, 19345353.
    • (2009) Int J Gynaecol Obstet , vol.105 , pp. 109
    • Creasman, W.1
  • 53
    • 84865039286 scopus 로고    scopus 로고
    • High TrkB expression levels are associated with poor prognosis and EMT induction in colorectal cancer cells
    • 10.1007/s00535-012-0532-0, 22361863
    • Fujikawa H, Tanaka K, Toiyama Y, Saigusa S, Inoue Y, Uchida K, Kusunoki M. High TrkB expression levels are associated with poor prognosis and EMT induction in colorectal cancer cells. J Gastroenterol 2012, 47:775-784. 10.1007/s00535-012-0532-0, 22361863.
    • (2012) J Gastroenterol , vol.47 , pp. 775-784
    • Fujikawa, H.1    Tanaka, K.2    Toiyama, Y.3    Saigusa, S.4    Inoue, Y.5    Uchida, K.6    Kusunoki, M.7
  • 54
    • 84873307557 scopus 로고    scopus 로고
    • STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells
    • 10.1016/j.cellsig.2013.01.011, 23333463
    • Wei Z, Jiang X, Qiao H, Zhai B, Zhang L, Zhang Q, Wu Y, Jiang H, Sun X. STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells. Cell Signal 2013, 25:931-938. 10.1016/j.cellsig.2013.01.011, 23333463.
    • (2013) Cell Signal , vol.25 , pp. 931-938
    • Wei, Z.1    Jiang, X.2    Qiao, H.3    Zhai, B.4    Zhang, L.5    Zhang, Q.6    Wu, Y.7    Jiang, H.8    Sun, X.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.