Intramembrane proteolysis within lysosomes

Ageing Research Reviews

Volumn 32, Issue , 2016, Pages 51-64

  Schröder, Bernd ^a   Saftig, Paul ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Alzheimer Disease; CD74; Intramembrane proteolysis; Lysosome; Signal peptide peptidase like 2a protease; Secretase

Indexed keywords

AMYLOID BETA PROTEIN; CD74 ANTIGEN; FAS LIGAND; GAMMA SECRETASE; INTRAMEMBRANE PROTEOLYSIS OF BRI2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMBRANE PROTEIN; MUTANT PROTEIN; PRESENILIN; SIGNAL PEPTIDE; SIGNAL PEPTIDE PEPTIDASE LIKE PROTEASE 2A; TRANSMEMBRANE PROTEIN 106B; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ASPARTIC PROTEINASE; B LYMPHOCYTE ANTIGEN; HLA ANTIGEN CLASS 2; INVARIANT CHAIN; SECRETASE; SIGNAL PEPTIDE PEPTIDASE;

ALZHEIMER DISEASE; CATALYSIS; CLINICAL TRIAL (TOPIC); ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME SUBSTRATE; HUMAN; INTRAMEMBRANE PROTEOLYSIS; LYSOSOME MEMBRANE; MOUSE MODEL; NONHUMAN; PHASE 3 CLINICAL TRIAL (TOPIC); PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN TARGETING; REVIEW; AGING; CELL MEMBRANE; ENZYMOLOGY; LYSOSOME; METABOLISM; NERVE DEGENERATION; PHYSIOLOGY;

AGING; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; ASPARTIC ACID ENDOPEPTIDASES; CELL MEMBRANE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; LYSOSOMES; MEMBRANE PROTEINS; NERVE DEGENERATION; PROTEOLYSIS;

EID: 84965140076     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2016.04.012     Document Type: Review

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