-
1
-
-
34547134198
-
Lysosomes: Fusion and function
-
Luzio, J. P., Pryor, P. R., & Bright, N. A. Lysosomes: fusion and function. Nat. Rev. Mol. Cell Biol. 8, 622-632 (2007
-
(2007)
Nat. Rev. Mol. Cell Biol
, vol.8
, pp. 622-632
-
-
Luzio, J.P.1
Pryor, P.R.2
Bright, N.A.3
-
2
-
-
84901670787
-
Lysosomal exocytosis and lipid storage disorders
-
Samie, M. A., & Xu, H. Lysosomal exocytosis and lipid storage disorders. J. Lipid Res. 55, 995-1009 (2014
-
(2014)
J. Lipid Res
, vol.55
, pp. 995-1009
-
-
Samie, M.A.1
Xu, H.2
-
3
-
-
84884154195
-
A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis
-
Samie, M., et al. A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis. Dev. Cell 26, 511-524 (2013
-
(2013)
Dev. Cell
, vol.26
, pp. 511-524
-
-
Samie, M.1
-
4
-
-
77953699711
-
Termination of autophagy and reformation of lysosomes regulated by mTOR
-
Yu, L., et al. Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature 465, 942-946 (2010
-
(2010)
Nature
, vol.465
, pp. 942-946
-
-
Yu, L.1
-
5
-
-
77955057326
-
3rd Linking molecular motors to membrane cargo
-
Akhmanova, A., & Hammer, J. A. 3rd Linking molecular motors to membrane cargo. Curr. Opin. Cell Biol. 22, 479-487 (2010
-
(2010)
Curr. Opin. Cell Biol
, vol.22
, pp. 479-487
-
-
Akhmanova, A.1
Hammer, J.A.2
-
6
-
-
79953316595
-
Lysosomal positioning coordinates cellular nutrient responses
-
Korolchuk, V. I., et al. Lysosomal positioning coordinates cellular nutrient responses. Nat. Cell Biol. 13, 453-460 (2011
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 453-460
-
-
Korolchuk, V.I.1
-
7
-
-
0032559260
-
And dynein superfamily proteins and the mechanism of organelle transport
-
Hirokawa, N. Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science 279, 519-526 (1998
-
(1998)
Science
, vol.279
, pp. 519-526
-
-
Hirokawa, N.1
Kinesin2
-
8
-
-
0034677929
-
The dynein microtubule motor
-
King, S. M. The dynein microtubule motor. Biochim. Biophys. Acta 1496, 60-75 (2000
-
(2000)
Biochim. Biophys. Acta
, vol.1496
, pp. 60-75
-
-
King, S.M.1
-
10
-
-
54049156405
-
The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel
-
Dong, X. P., et al. The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel. Nature 455, 992-996 (2008
-
(2008)
Nature
, vol.455
, pp. 992-996
-
-
Dong, X.P.1
-
11
-
-
77949696020
-
Mucolipins: Intracellular TRPML1-3 channels
-
Cheng, X., Shen, D., Samie, M., & Xu, H. Mucolipins: intracellular TRPML1-3 channels. FEBS Lett. 584, 2013-2021 (2010
-
(2010)
FEBS Lett
, vol.584
, pp. 2013-2021
-
-
Cheng, X.1
Shen, D.2
Samie, M.3
Xu, H.4
-
12
-
-
0033760264
-
Cloning of the gene encoding a novel integral membrane protein, mucolipidin-and identification of the two major founder mutations causing mucolipidosis type IV
-
Bassi, M. T., et al. Cloning of the gene encoding a novel integral membrane protein, mucolipidin-and identification of the two major founder mutations causing mucolipidosis type IV. Am. J. Human Genet. 67, 1110-1120 (2000
-
(2000)
Am. J. Human Genet
, vol.67
, pp. 1110-1120
-
-
Bassi, M.T.1
-
13
-
-
0032568565
-
Abnormal transport along the lysosomal pathway in mucolipidosis, type IV disease
-
Chen, C. S., Bach, G., & Pagano, R. E. Abnormal transport along the lysosomal pathway in mucolipidosis, type IV disease. Proc. Natl Acad. Sci. USA 95, 6373-6378 (1998
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 6373-6378
-
-
Chen, C.S.1
Bach, G.2
Pagano, R.E.3
-
14
-
-
35348829780
-
Neurologic, gastric, and opthalmologic pathologies in a murine model of mucolipidosis type IV
-
Venugopal, B., et al. Neurologic, gastric, and opthalmologic pathologies in a murine model of mucolipidosis type IV. Am. J. Human Genet. 81, 1070-1083 (2007
-
(2007)
Am. J. Human Genet
, vol.81
, pp. 1070-1083
-
-
Venugopal, B.1
-
15
-
-
84939778375
-
The phosphoinositide-gated lysosomal Ca(2+) channel, TRPML1, is required for phagosome maturation
-
Dayam, R. M., Saric, A., Shilliday, R. E., & Botelho, R. J. The phosphoinositide-gated lysosomal Ca(2+) channel, TRPML1, is required for phagosome maturation. Traffic 16, 1010-1026 (2015)
-
(2015)
Traffic
, vol.16
, pp. 1010-1026
-
-
Dayam, R.M.1
Saric, A.2
Shilliday, R.E.3
Botelho, R.J.4
-
16
-
-
84922794140
-
Lysosomal physiology
-
Xu, H., & Ren, D. Lysosomal physiology. Annu. Rev. Physiol. 77, 57-80 (2015
-
(2015)
Annu. Rev. Physiol.
, vol.77
, pp. 57-80
-
-
Xu, H.1
Ren, D.2
-
17
-
-
84885821254
-
Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes
-
Xu, M., et al. Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes. Biochim. Biophys. Acta 1833, 3228-3236 (2013
-
(2013)
Biochim. Biophys. Acta 1833
, pp. 3228-3236
-
-
Xu, M.1
-
18
-
-
47149089713
-
Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes
-
Kimura, S., Noda, T., & Yoshimori, T. Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes. Cell Struct. Funct. 33, 109-122 (2008
-
(2008)
Cell Struct. Funct
, vol.33
, pp. 109-122
-
-
Kimura, S.1
Noda, T.2
Yoshimori, T.3
-
19
-
-
65549145048
-
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
-
Thoreen, C. C., et al. An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. J. Biol. Chem. 284, 8023-8032 (2009
-
(2009)
J. Biol. Chem
, vol.284
, pp. 8023-8032
-
-
Thoreen, C.C.1
-
20
-
-
79955075253
-
Macroautophagy is defective in mucolipin-1-deficient mouse neurons
-
Curcio-Morelli, C., et al. Macroautophagy is defective in mucolipin-1-deficient mouse neurons. Neurobiol. Dis. 40, 370-377 (2010
-
(2010)
Neurobiol. Dis
, vol.40
, pp. 370-377
-
-
Curcio-Morelli, C.1
-
21
-
-
49649089300
-
Autophagic dysfunction in mucolipidosis type IV patients
-
Vergarajauregui, S., Connelly, P. S., Daniels, M. P., & Puertollano, R. Autophagic dysfunction in mucolipidosis type IV patients. Human Mol. Genet. 17, 2723-2737 (2008
-
(2008)
Human Mol. Genet
, vol.17
, pp. 2723-2737
-
-
Vergarajauregui, S.1
Connelly, P.S.2
Daniels, M.P.3
Puertollano, R.4
-
22
-
-
84921960605
-
The intracellular Ca channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy
-
Cheng, X., et al. The intracellular Ca channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy. Nat. Med. 20, 1187-1192 (2014
-
(2014)
Nat. Med
, vol.20
, pp. 1187-1192
-
-
Cheng, X.1
-
23
-
-
84925324770
-
Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation
-
Wang, W., et al. Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation. Proc. Natl Acad. Sci. USA 112, E1373-E1381 (2015
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. E1373-E1381
-
-
Wang, W.1
-
24
-
-
84859175854
-
Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release
-
Shen, D., et al. Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release. Nat. Commun. 3, 731 (2012
-
(2012)
Nat. Commun
, vol.3
, pp. 731
-
-
Shen, D.1
-
25
-
-
38949156866
-
Cholesterol level regulates endosome motility via Rab proteins
-
Chen, H., Yang, J., Low, P. S., & Cheng, J. X. Cholesterol level regulates endosome motility via Rab proteins. Biophys. J. 94, 1508-1520 (2008
-
(2008)
Biophys. J.
, vol.94
, pp. 1508-1520
-
-
Chen, H.1
Yang, J.2
Low, P.S.3
Cheng, J.X.4
-
26
-
-
67649600680
-
Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning
-
Rocha, N., et al. Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning. J. Cell Biol. 185, 1209-1225 (2009
-
(2009)
J. Cell Biol
, vol.185
, pp. 1209-1225
-
-
Rocha, N.1
-
27
-
-
84899976153
-
Visualization of cholesterol deposits in lysosomes of Niemann- Pick type C fibroblasts using recombinant perfringolysin O
-
Kwiatkowska, K., et al. Visualization of cholesterol deposits in lysosomes of Niemann- Pick type C fibroblasts using recombinant perfringolysin O. Orphanet J. Rare Dis. 9, 64 (2014
-
(2014)
Orphanet J. Rare Dis
, vol.9
, pp. 64
-
-
Kwiatkowska, K.1
-
28
-
-
0042163785
-
Trafficking defects in endogenously synthesized cholesterol in fibroblasts, macrophages, hepatocytes, and glial cells from Niemann- Pick type C1 mice
-
Reid, P. C., Sugii, S., & Chang, T. Y. Trafficking defects in endogenously synthesized cholesterol in fibroblasts, macrophages, hepatocytes, and glial cells from Niemann- Pick type C1 mice. J. Lipid Res. 44, 1010-1019 (2003
-
(2003)
J. Lipid Res
, vol.44
, pp. 1010-1019
-
-
Reid, P.C.1
Sugii, S.2
Chang, T.Y.3
-
30
-
-
39549098329
-
Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease
-
Spinosa, M. R., et al. Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease. J. Neurosci. 28, 1640-1648 (2008
-
(2008)
J. Neurosci
, vol.28
, pp. 1640-1648
-
-
Spinosa, M.R.1
-
31
-
-
0035865135
-
Rab-interacting lysosomal protein (RILP): The Rab7 effector required for transport to lysosomes
-
Cantalupo, G., Alifano, P., Roberti, V., Bruni, C. B., & Bucci, C. Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes. EMBO J. 20, 683-693 (2001
-
(2001)
EMBO J.
, vol.20
, pp. 683-693
-
-
Cantalupo, G.1
Alifano, P.2
Roberti, V.3
Bruni, C.B.4
Bucci, C.5
-
32
-
-
0033999818
-
Rab7: A key to lysosome biogenesis
-
Bucci, C., Thomsen, P., Nicoziani, P., McCarthy, J., & vanDeurs, B. Rab7: a key to lysosome biogenesis. Mol. Biol. Cell 11, 467-480 (2000
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 467-480
-
-
Bucci, C.1
Thomsen, P.2
Nicoziani, P.3
McCarthy, J.4
Van Deurs, B.5
-
33
-
-
84891368628
-
Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics
-
Li, X., et al. Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics. Proc. Natl Acad. Sci. USA 110, 21165-21170 (2013
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 21165-21170
-
-
Li, X.1
-
34
-
-
84921615639
-
PI(5)P regulates autophagosome biogenesis
-
Vicinanza, M., et al. PI(5)P regulates autophagosome biogenesis. Mol. Cell 57, 219-234 (2015
-
(2015)
Mol. Cell
, vol.57
, pp. 219-234
-
-
Vicinanza, M.1
-
35
-
-
80051473235
-
PI(35)P(2) controls membrane trafficking by direct activation of mucolipin Ca2C release channels in the endolysosome
-
Dong, X. P., et al. PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca2C release channels in the endolysosome. Nat. Commun. 1, 38 (2010
-
(2010)
Nat. Commun.
, vol.1
, pp. 38
-
-
Dong, X.P.1
-
36
-
-
84863922724
-
Phosphoinositide isoforms determine compartment-specific ion channel activity
-
Zhang, X., Li, X., & Xu, H. Phosphoinositide isoforms determine compartment-specific ion channel activity. Proc. Natl Acad. Sci. USA 109, 11384-11389 (2012
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 11384-11389
-
-
Zhang, X.1
Li, X.2
Xu, H.3
-
37
-
-
38949207192
-
A selective PIKfyve inhibitor blocks PtdIns(35)P2 production and disrupts endomembrane transport and retroviral budding
-
Jefferies, H. B., et al. A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding. EMBO Rep. 9, 164-170 (2008
-
(2008)
EMBO Rep.
, vol.9
, pp. 164-170
-
-
Jefferies, H.B.1
-
38
-
-
84875435923
-
Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death
-
Martin, S., et al. Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death. PLoS ONE 8, e60152 (2013
-
(2013)
PLoS ONE
, vol.8
, pp. e60152
-
-
Martin, S.1
-
39
-
-
84926644537
-
The Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole
-
Ho, C. Y., Choy, C. H., Wattson, C. A., Johnson, D. E., & Botelho, R. J. The Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole. J. Biol. Chem. 290, 9919-9928 (2015
-
(2015)
J. Biol. Chem
, vol.290
, pp. 9919-9928
-
-
Ho, C.Y.1
Choy, C.H.2
Wattson, C.A.3
Johnson, D.E.4
Botelho, R.J.5
-
40
-
-
84880888092
-
PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling
-
Cai, X., et al. PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling. Chem. Biol. 20, 912-921 (2013
-
(2013)
Chem. Biol
, vol.20
, pp. 912-921
-
-
Cai, X.1
-
41
-
-
70350446761
-
Traffic control: Regulation of kinesin motors
-
Verhey, K. J., & Hammond, J. W. Traffic control: regulation of kinesin motors. Nat. Rev. Mol. Cell Biol. 10, 765-777 (2009
-
(2009)
Nat. Rev. Mol. Cell Biol
, vol.10
, pp. 765-777
-
-
Verhey, K.J.1
Hammond, J.W.2
-
42
-
-
83455229793
-
Arl8 and SKIP act together to link lysosomes to kinesin-1
-
Rosa-Ferreira, C., & Munro, S. Arl8 and SKIP act together to link lysosomes to kinesin-1. Dev. Cell 21, 1171-1178 (2011
-
(2011)
Dev. Cell
, vol.21
, pp. 1171-1178
-
-
Rosa-Ferreira, C.1
Munro, S.2
-
43
-
-
0032568790
-
Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria
-
Tanaka, Y., et al. Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell 93, 1147-1158 (1998
-
(1998)
Cell
, vol.93
, pp. 1147-1158
-
-
Tanaka, Y.1
-
44
-
-
0035975946
-
The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors
-
Jordens, I., et al. The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors. Curr. Biol. 11, 1680-1685 (2001
-
(2001)
Curr. Biol
, vol.11
, pp. 1680-1685
-
-
Jordens, I.1
-
45
-
-
33847003020
-
Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued ORP1L and the receptor betalll spectrin
-
Johansson, M., et al. Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin. J. Cell Biol. 176, 459-471 (2007
-
(2007)
J. Cell Biol
, vol.176
, pp. 459-471
-
-
Johansson, M.1
-
46
-
-
79251563457
-
Kinesin 5B is necessary for delivery of membrane and receptors during FcgammaR-mediated phagocytosis
-
Silver, K. E., & Harrison, R. E. Kinesin 5B is necessary for delivery of membrane and receptors during FcgammaR-mediated phagocytosis. J. Immunol. 186, 816-825 (2011
-
(2011)
J. Immunol
, vol.186
, pp. 816-825
-
-
Silver, K.E.1
Harrison, R.E.2
-
47
-
-
0345306571
-
Analysis of the dynein-dynactin interaction in vitro and in vivo
-
King, S. J., Brown, C. L., Maier, K. C., Quintyne, N. J., & Schroer, T. A. Analysis of the dynein-dynactin interaction in vitro and in vivo. Mol. Biol. Cell 14, 5089-5097 (2003
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 5089-5097
-
-
King, S.J.1
Brown, C.L.2
Maier, K.C.3
Quintyne, N.J.4
Schroer, T.A.5
-
48
-
-
84931022346
-
The dynein inhibitor Ciliobrevin D inhibits the bidirectional transport of organelles along sensory axons and impairs NGF-mediated regulation of growth cones and axon branches
-
Sainath, R., & Gallo, G. The dynein inhibitor Ciliobrevin D inhibits the bidirectional transport of organelles along sensory axons and impairs NGF-mediated regulation of growth cones and axon branches. Dev. Neurobiol. 75, 757-777 (2014
-
(2014)
Dev. Neurobiol
, vol.75
, pp. 757-777
-
-
Sainath, R.1
Gallo, G.2
-
49
-
-
84862814996
-
Small-molecule inhibitors of the AAAC ATPase motor cytoplasmic dynein
-
Firestone, A. J., et al. Small-molecule inhibitors of the AAAC ATPase motor cytoplasmic dynein. Nature 484, 125-129 (2012
-
(2012)
Nature
, vol.484
, pp. 125-129
-
-
Firestone, A.J.1
-
50
-
-
79960623087
-
Structure and function of ALG-2, a penta-EFhand calcium-dependent adaptor protein
-
Maki, M., Suzuki, H., & Shibata, H. Structure and function of ALG-2, a penta-EFhand calcium-dependent adaptor protein. Sci. China Life Sci. 54, 770-779 (2011
-
(2011)
Sci. China Life Sci
, vol.54
, pp. 770-779
-
-
Maki, M.1
Suzuki, H.2
Shibata, H.3
-
51
-
-
73649127260
-
Identification of the penta-EFhand protein ALG-2 as a Ca2C-dependent interactor of mucolipin-1
-
Vergarajauregui, S., Martina, J. A., & Puertollano, R. Identification of the penta-EFhand protein ALG-2 as a Ca2C-dependent interactor of mucolipin-1. J. Biol. Chem. 284, 36357-36366 (2009
-
(2009)
J. Biol. Chem
, vol.284
, pp. 36357-36366
-
-
Vergarajauregui, S.1
Martina, J.A.2
Puertollano, R.3
-
52
-
-
84950126700
-
Genome engineering using CRISPR-Cas9 system
-
Cong, L., & Zhang, F. Genome engineering using CRISPR-Cas9 system. Methods Mol. Biol. 1239, 197-217 (2015
-
(2015)
Methods Mol. Biol
, vol.1239
, pp. 197-217
-
-
Cong, L.1
Zhang, F.2
-
53
-
-
84955200036
-
Rab7 and Arl8 GTPases are necessary for lysosome tubulation in macrophages
-
Mrakovic, A., Kay, J. G., Furuya, W., Brumell, J. H., & Botelho, R. J. Rab7 and Arl8 GTPases are necessary for lysosome tubulation in macrophages. Traffic 13, 1667-1679 (2012
-
(2012)
Traffic
, vol.13
, pp. 1667-1679
-
-
Mrakovic, A.1
Kay, J.G.2
Furuya, W.3
Brumell, J.H.4
Botelho, R.J.5
-
54
-
-
0019333905
-
New calcium indicators and buffers with high selectivity against magnesium and protons: Design synthesis and properties of prototype structures
-
Tsien, R. Y. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry 19, 2396-2404 (1980
-
(1980)
Biochemistry
, vol.19
, pp. 2396-2404
-
-
Tsien, R.Y.1
-
55
-
-
58049198294
-
VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(35)P(2) in yeast and mouse
-
Jin, N., et al. VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse. EMBO J. 27, 3221-3234 (2008
-
(2008)
EMBO J.
, vol.27
, pp. 3221-3234
-
-
Jin, N.1
-
56
-
-
84867908738
-
In vivo Pikfyve generates PI(35)P2, which serves as both a signaling lipid and the major precursor for PI5P
-
Zolov, S. N., et al. In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P. Proc. Natl Acad. Sci. USA 109, 17472-17477 (2012
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 17472-17477
-
-
Zolov, S.N.1
-
57
-
-
84941354274
-
The mucolipidosis IV Ca2C channel TRPML1 (MCOLN1) is regulated by the TOR kinase
-
Onyenwoke, R. U., et al. The mucolipidosis IV Ca2C channel TRPML1 (MCOLN1) is regulated by the TOR kinase. Biochem. J. 470, 331-342 (2015
-
(2015)
Biochem. J.
, vol.470
, pp. 331-342
-
-
Onyenwoke, R.U.1
-
58
-
-
84866163103
-
Drosophila TRPML is required for TORC1 activation
-
Wong, C. O., Li, R., Montell, C., & Venkatachalam, K. Drosophila TRPML is required for TORC1 activation. Curr. Biol. 22, 1616-1621 (2012
-
(2012)
Curr. Biol
, vol.22
, pp. 1616-1621
-
-
Wong, C.O.1
Li, R.2
Montell, C.3
Venkatachalam, K.4
-
59
-
-
84923228346
-
Mucolipidosis type IV protein TRPML1-dependent lysosome formation
-
Miller, A., et al. Mucolipidosis type IV protein TRPML1-dependent lysosome formation. Traffic 16, 284-297 (2014
-
(2014)
Traffic
, vol.16
, pp. 284-297
-
-
Miller, A.1
-
60
-
-
84923820926
-
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
-
Medina, D. L., et al. Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB. Nat. Cell Biol. 17, 288-299 (2015
-
(2015)
Nat. Cell Biol
, vol.17
, pp. 288-299
-
-
Medina, D.L.1
-
61
-
-
84906544287
-
Apoptosis-linked gene-2 (ALG-2)/Sec31 interactions regulate endoplasmic reticulum (ER)-to-Golgi transport: A potential effector pathway for luminal calcium
-
Helm, J. R., et al. Apoptosis-linked gene-2 (ALG-2)/Sec31 interactions regulate endoplasmic reticulum (ER)-to-Golgi transport: a potential effector pathway for luminal calcium. J. Biol. Chem. 289, 23609-23628 (2014
-
(2014)
J. Biol. Chem
, vol.289
, pp. 23609-23628
-
-
Helm, J.R.1
-
62
-
-
0346018912
-
Tubular lysosome morphology and distribution within macrophages depend on the integrity of cytoplasmic microtubules
-
Swanson, J., Bushnell, A., & Silverstein, S. C. Tubular lysosome morphology and distribution within macrophages depend on the integrity of cytoplasmic microtubules. Proc. Natl Acad. Sci. USA 84, 1921-1925 (1987
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 1921-1925
-
-
Swanson, J.1
Bushnell, A.2
Silverstein, S.C.3
-
63
-
-
84870730914
-
Autophagic lysosome reformation
-
Chen, Y., & Yu, L. Autophagic lysosome reformation. Exp. Cell Res. 319, 142-146 (2013
-
(2013)
Exp. Cell Res
, vol.319
, pp. 142-146
-
-
Chen, Y.1
Yu, L.2
-
64
-
-
84865776097
-
Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation
-
Rong, Y., et al. Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation. Nat. Cell Biol. 14, 924-934 (2012
-
(2012)
Nat. Cell Biol
, vol.14
, pp. 924-934
-
-
Rong, Y.1
-
65
-
-
79956346329
-
Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation
-
Rong, Y., et al. Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation. Proc. Natl Acad. Sci. USA 108, 7826-7831 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 7826-7831
-
-
Rong, Y.1
-
66
-
-
84915793059
-
Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation
-
Chang, J., Lee, S., & Blackstone, C. Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation. J. Clin. Invest. 124, 5249-5262 (2014
-
(2014)
J. Clin. Invest
, vol.124
, pp. 5249-5262
-
-
Chang, J.1
Lee, S.2
Blackstone, C.3
-
67
-
-
0030727535
-
Overexpression of the dynamitin p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution
-
Burkhardt, J. K., Echeverri, C. J., Nilsson, T., & Vallee, R. B. Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J. Cell Biol. 139, 469-484 (1997
-
(1997)
J. Cell Biol
, vol.139
, pp. 469-484
-
-
Burkhardt, J.K.1
Echeverri, C.J.2
Nilsson, T.3
Vallee, R.B.4
-
68
-
-
83255193923
-
The enlarged lysosomes in beigej cells result from decreased lysosome fission and not increased lysosome fusion
-
Durchfort, N., et al. The enlarged lysosomes in beigej cells result from decreased lysosome fission and not increased lysosome fusion. Traffic 13, 108-119 (2012
-
(2012)
Traffic
, vol.13
, pp. 108-119
-
-
Durchfort, N.1
-
69
-
-
84927126103
-
Cholesterol transport through lysosome-peroxisome membrane contacts
-
Chu, B. B., et al. Cholesterol transport through lysosome-peroxisome membrane contacts. Cell 161, 291-306 (2015
-
(2015)
Cell
, vol.161
, pp. 291-306
-
-
Chu, B.B.1
-
70
-
-
84867565289
-
TPC proteins are phosphoinositide-activated sodium-selective ion channels in endosomes and lysosomes
-
Wang, X., et al. TPC proteins are phosphoinositide-activated sodium-selective ion channels in endosomes and lysosomes. Cell 151, 372-383 (2012
-
(2012)
Cell
, vol.151
, pp. 372-383
-
-
Wang, X.1
|