Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes

Molecular Brain

Volumn 8, Issue 1, 2015, Pages

  Tang, Weihao ^a,b   Tam, Joshua H K ^a,b   Seah, Claudia ^a   Chiu, Justin ^a,b   Tyrer, Andrea ^a,b   Cregan, Sean P ^a,b   Meakin, Susan O ^a,b   Pasternak, Stephen H ^a,b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b WESTERN UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 6; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; ACTIN; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 1; ADP-RIBOSYLATION FACTOR 6; ALCOHOL DEHYDROGENASE; C-TERMINAL BINDING PROTEIN; CROSS LINKING REAGENT; DEXTRAN; DNA BINDING PROTEIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MUTANT PROTEIN; RAC1 PROTEIN; SMALL INTERFERING RNA;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; BRAIN CORTEX; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENDOSOME; HIPPOCAMPUS; LYSOSOME; MOUSE; NONHUMAN; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN TRANSPORT; REGULATORY MECHANISM; ANIMAL; BIOSYNTHESIS; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CELL SURVIVAL; GENE SILENCING; HUMAN; METABOLISM; PATHOLOGY; TUMOR CELL LINE; ULTRASTRUCTURE;

ACTINS; ADP-RIBOSYLATION FACTOR 1; ADP-RIBOSYLATION FACTORS; ALCOHOL OXIDOREDUCTASES; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CELL COMPARTMENTATION; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; CROSS-LINKING REAGENTS; DEXTRANS; DNA-BINDING PROTEINS; ENDOSOMES; GENE KNOCKDOWN TECHNIQUES; HIPPOCAMPUS; HUMANS; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOMES; MICE; MUTANT PROTEINS; PINOCYTOSIS; PROTEIN TRANSPORT; RAC1 GTP-BINDING PROTEIN; RNA, SMALL INTERFERING;

EID: 84937216724     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/s13041-015-0129-7     Document Type: Article

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