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Volumn 6, Issue , 2014, Pages

Proteostasis and longevity: When does aging really begin?

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EID: 84894254592     PISSN: None     EISSN: 20517599     Source Type: Journal    
DOI: 10.12703/P6-7     Document Type: Review
Times cited : (100)

References (63)
  • 2
    • 44849094781 scopus 로고    scopus 로고
    • Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
    • Morimoto RI: Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging. Genes Dev 2008, 22:1427-38.
    • (2008) Genes Dev , vol.22 , pp. 1427-1438
    • Morimoto, R.I.1
  • 4
    • 84866272849 scopus 로고    scopus 로고
    • Quantitative in vivo redox sensors uncover oxidative stress as an early event in life
    • Knoefler D, Thamsen M, Koniczek M, Niemuth NJ, Diederich A, Jakob U: Quantitative in vivo redox sensors uncover oxidative stress as an early event in life. Mol Cell 2012, 47:767-76.
    • (2012) Mol Cell , vol.47 , pp. 767-776
    • Knoefler, D.1    Thamsen, M.2    Koniczek, M.3    Niemuth, N.J.4    Diederich, A.5    Jakob, U.6
  • 5
    • 84878118233 scopus 로고    scopus 로고
    • Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
    • Rana A, Rera M, Walker DW: Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan. Proc Natl Acad Sci USA 2013, 110:8638-43.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 8638-8643
    • Rana, A.1    Rera, M.2    Walker, D.W.3
  • 6
    • 78650918920 scopus 로고    scopus 로고
    • FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
    • Demontis F, Perrimon N: FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell 2010, 143:813-25.
    • (2010) Cell , vol.143 , pp. 813-825
    • Demontis, F.1    Perrimon, N.2
  • 8
    • 39349083915 scopus 로고    scopus 로고
    • Adapting proteostasis for disease intervention
    • DOI 10.1126/science.1141448
    • Balch WE, Morimoto RI, Dillin A, Kelly JW: Adapting proteostasis for disease intervention. Science 2008, 319:916-9. (Pubitemid 351263754)
    • (2008) Science , vol.319 , Issue.5865 , pp. 916-919
    • Balch, W.E.1    Morimoto, R.I.2    Dillin, A.3    Kelly, J.W.4
  • 9
    • 70349266064 scopus 로고    scopus 로고
    • Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
    • Ben-Zvi A, Miller EA, Morimoto RI: Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging. Proc Natl Acad Sci USA 2009, 106:14914-9.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14914-14919
    • Ben-Zvi, A.1    Miller, E.A.2    Morimoto, R.I.3
  • 11
    • 33847251514 scopus 로고    scopus 로고
    • Genetic and pharmacological factors that influence reproductive aging in nematodes
    • Hughes SE, Evason K, Xiong C, Kornfeld K: Genetic and pharmacological factors that influence reproductive aging in nematodes. PLoS Genet 2007, 3:e25.
    • (2007) PLoS Genet , vol.3
    • Hughes, S.E.1    Evason, K.2    Xiong, C.3    Kornfeld, K.4
  • 12
    • 84862848780 scopus 로고    scopus 로고
    • Ribosome-associated chaperones as key players in proteostasis
    • Preissler S, Deuerling E: Ribosome-associated chaperones as key players in proteostasis. Trends Biochem Sci 2012, 37:274-83.
    • (2012) Trends Biochem Sci , vol.37 , pp. 274-283
    • Preissler, S.1    Deuerling, E.2
  • 13
    • 84878658572 scopus 로고    scopus 로고
    • The nascent polypeptide-associated complex is a key regulator of proteostasis
    • Kirstein-Miles J, Scior A, Deuerling E, Morimoto RI: The nascent polypeptide-associated complex is a key regulator of proteostasis. EMBO J 2013, 32:1451-68.
    • (2013) EMBO J , vol.32 , pp. 1451-1468
    • Kirstein-Miles, J.1    Scior, A.2    Deuerling, E.3    Morimoto, R.I.4
  • 14
    • 0038701745 scopus 로고    scopus 로고
    • Regulation of aging and age-related disease by DAF-16 and heat-shock factor
    • DOI 10.1126/science.1083701
    • Hsu A, Murphy CT, Kenyon C: Regulation of aging and agerelated disease by DAF-16 and heat-shock factor. Science 2003, 300:1142-5. (Pubitemid 36583098)
    • (2003) Science , vol.300 , Issue.5622 , pp. 1142-1145
    • Hsu, A.-L.1    Murphy, C.T.2    Kenyon, C.3
  • 15
    • 79953231709 scopus 로고    scopus 로고
    • A longer and healthier life with TOR down-regulation: Genetics and drugs
    • Bjedov I, Partridge L: A longer and healthier life with TOR down-regulation: genetics and drugs. Biochem Soc Trans 2011, 39:460-5.
    • (2011) Biochem Soc Trans , vol.39 , pp. 460-465
    • Bjedov, I.1    Partridge, L.2
  • 17
    • 65649115267 scopus 로고    scopus 로고
    • Recognition and processing of ubiquitin-protein conjugates by the proteasome
    • Finley D: Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu Rev Biochem 2009, 78:477-513.
    • (2009) Annu Rev Biochem , vol.78 , pp. 477-513
    • Finley, D.1
  • 20
    • 77953020414 scopus 로고    scopus 로고
    • A photoconvertible reporter of the ubiquitin-proteasome system in vivo
    • Hamer G, Matilainen O, Holmberg CI: A photoconvertible reporter of the ubiquitin-proteasome system in vivo. Nat Methods 2010, 7:473-8.
    • (2010) Nat Methods , vol.7 , pp. 473-478
    • Hamer, G.1    Matilainen, O.2    Holmberg, C.I.3
  • 21
    • 79961023008 scopus 로고    scopus 로고
    • EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan
    • Liu G, Rogers J, Murphy CT, Rongo C: EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan. EMBO J 2011, 30:2990-3003.
    • (2011) EMBO J , vol.30 , pp. 2990-3003
    • Liu, G.1    Rogers, J.2    Murphy, C.T.3    Rongo, C.4
  • 22
    • 79955366725 scopus 로고    scopus 로고
    • A screenable in vivo assay to study proteostasis networks in Caenorhabditis elegans
    • Segref A, Torres S, Hoppe T: A screenable in vivo assay to study proteostasis networks in Caenorhabditis elegans. Genetics 2011, 187:1235-40.
    • (2011) Genetics , vol.187 , pp. 1235-1240
    • Segref, A.1    Torres, S.2    Hoppe, T.3
  • 24
    • 84883477931 scopus 로고    scopus 로고
    • Functional aging in the nervous system contributes to age-dependent motor activity decline in C. elegans
    • Liu J, Zhang B, Lei H, Feng Z, Liu J, Hsu A, Xu XZS: Functional aging in the nervous system contributes to age-dependent motor activity decline in C. elegans. Cell Metab 2013, 18:392-402.
    • (2013) Cell Metab , vol.18 , pp. 392-402
    • Liu, J.1    Zhang, B.2    Lei, H.3    Feng, Z.4    Liu, J.5    Hsu, A.6    Xu, X.Z.S.7
  • 25
    • 59449095881 scopus 로고    scopus 로고
    • Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process
    • Tonoki A, Kuranaga E, Tomioka T, Hamazaki J, Murata S, Tanaka K, Miura M: Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process. Mol Cell Biol 2009, 29:1095-106.
    • (2009) Mol Cell Biol , vol.29 , pp. 1095-1106
    • Tonoki, A.1    Kuranaga, E.2    Tomioka, T.3    Hamazaki, J.4    Murata, S.5    Tanaka, K.6    Miura, M.7
  • 26
    • 0034087369 scopus 로고    scopus 로고
    • Decreased levels of proteasome activity and proteasome expression in aging spinal cord
    • DOI 10.1016/S0306-4522(00)00067-1, PII S0306452200000671
    • Keller JN, Huang FF, Markesbery WR: Decreased levels of proteasome activity and proteasome expression in aging spinal cord. Neuroscience 2000, 98:149-56. (Pubitemid 30349153)
    • (2000) Neuroscience , vol.98 , Issue.1 , pp. 149-156
    • Keller, J.N.1    Huang, F.F.2    Markesbery, W.R.3
  • 27
    • 67651004289 scopus 로고    scopus 로고
    • A conserved ubiquitination pathway determines longevity in response to diet restriction
    • Carrano AC, Liu Z, Dillin A, Hunter T: A conserved ubiquitination pathway determines longevity in response to diet restriction. Nature 2009, 460:396-9.
    • (2009) Nature , vol.460 , pp. 396-399
    • Carrano, A.C.1    Liu, Z.2    Dillin, A.3    Hunter, T.4
  • 34
    • 79955631150 scopus 로고    scopus 로고
    • Autophagy in the cellular energetic balance
    • Singh R, Cuervo AM: Autophagy in the cellular energetic balance. Cell Metab 2011, 13:495-504.
    • (2011) Cell Metab , vol.13 , pp. 495-504
    • Singh, R.1    Cuervo, A.M.2
  • 35
    • 77954955686 scopus 로고    scopus 로고
    • Heat shock factors: Integrators of cell stress, development and lifespan
    • Akerfelt M, Morimoto RI, Sistonen L: Heat shock factors: integrators of cell stress, development and lifespan. Nat Rev Mol Cell Biol 2010, 11:545-55.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 545-555
    • Akerfelt, M.1    Morimoto, R.I.2    Sistonen, L.3
  • 36
    • 82255173966 scopus 로고    scopus 로고
    • The unfolded protein response: From stress pathway to homeostatic regulation
    • Walter P, Ron D: The unfolded protein response: from stress pathway to homeostatic regulation. Science 2011, 334:1081-6.
    • (2011) Science , vol.334 , pp. 1081-1086
    • Walter, P.1    Ron, D.2
  • 37
    • 77953012548 scopus 로고    scopus 로고
    • Stress-activated cap'n'collar transcription factors in aging and human disease
    • Sykiotis GP, Bohmann D: Stress-activated cap'n'collar transcription factors in aging and human disease. Sci Signal 2010, 3:re3.
    • (2010) Sci Signal , vol.3
    • Sykiotis, G.P.1    Bohmann, D.2
  • 38
    • 77950200010 scopus 로고    scopus 로고
    • The genetics of ageing
    • Kenyon CJ: The genetics of ageing. Nature 2010, 464:504-12.
    • (2010) Nature , vol.464 , pp. 504-512
    • Kenyon, C.J.1
  • 40
    • 84879602902 scopus 로고    scopus 로고
    • Evaluating and responding to mitochondrial dysfunction: The mitochondrial unfoldedprotein response and beyond
    • Haynes CM, Fiorese CJ, Lin Y: Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfoldedprotein response and beyond. Trends Cell Biol 2013, 23:311-8.
    • (2013) Trends Cell Biol , vol.23 , pp. 311-318
    • Haynes, C.M.1    Fiorese, C.J.2    Lin, Y.3
  • 42
    • 0742323000 scopus 로고    scopus 로고
    • Regulation of Longevity in Caenorhabditis elegans by Heat Shock Factor and Molecular Chaperones
    • DOI 10.1091/mbc.E03-07-0532
    • Morley JF, Morimoto RI: Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones. Mol Biol Cell 2004, 15:657-64. (Pubitemid 38146482)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.2 , pp. 657-664
    • Morley, J.F.1    Morimoto, R.I.2
  • 43
    • 84879343155 scopus 로고    scopus 로고
    • XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity
    • Taylor RC, Dillin A: XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity. Cell 2013, 153:1435-47.
    • (2013) Cell , vol.153 , pp. 1435-1447
    • Taylor, R.C.1    Dillin, A.2
  • 44
    • 40849118472 scopus 로고    scopus 로고
    • Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans
    • DOI 10.1016/j.cell.2008.01.030, PII S009286740800130X
    • Tullet JMA, Hertweck M, An JH, Baker J, Hwang JY, Liu S, Oliveira RP, Baumeister R, Blackwell TK: Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell 2008, 132:1025-38. (Pubitemid 351391953)
    • (2008) Cell , vol.132 , Issue.6 , pp. 1025-1038
    • Tullet, J.M.A.1    Hertweck, M.2    An, J.H.3    Baker, J.4    Hwang, J.Y.5    Liu, S.6    Oliveira, R.P.7    Baumeister, R.8    Blackwell, T.K.9
  • 45
    • 84880514122 scopus 로고    scopus 로고
    • Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes
    • Rahman MM, Sykiotis GP, Nishimura M, Bodmer R, Bohmann D: Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes. Aging Cell 2013, 12:554-62.
    • (2013) Aging Cell , vol.12 , pp. 554-562
    • Rahman, M.M.1    Sykiotis, G.P.2    Nishimura, M.3    Bodmer, R.4    Bohmann, D.5
  • 46
  • 47
    • 0025821986 scopus 로고
    • Concomitant decline in heat-induced hyperthermia and HSP70 mRNA expression in aged rats
    • Blake MJ, Fargnoli J, Gershon D, Holbrook NJ: Concomitant decline in heat-induced hyperthermia and HSP70 mRNA expression in aged rats. Am J Physiol 1991, 260:R663-7.
    • (1991) Am J Physiol , vol.260
    • Blake, M.J.1    Fargnoli, J.2    Gershon, D.3    Holbrook, N.J.4
  • 48
    • 84883767608 scopus 로고    scopus 로고
    • Germline stem cell arrest inhibits the collapse of somatic proteostasis early in Caenorhabditis elegans adulthood
    • Shemesh N, Shai N, Ben-Zvi A: Germline stem cell arrest inhibits the collapse of somatic proteostasis early in Caenorhabditis elegans adulthood. Aging Cell 2013, 12:814-22.
    • (2013) Aging Cell , vol.12 , pp. 814-822
    • Shemesh, N.1    Shai, N.2    Ben-Zvi, A.3
  • 51
    • 33751420477 scopus 로고    scopus 로고
    • Microarray analysis of variation in individual aging C. elegans: Approaches and challenges
    • DOI 10.1016/j.exger.2006.06.034, PII S0531556506002166
    • Golden TR, Hubbard A, Melov S: Microarray analysis of variation in individual aging C. elegans: approaches and challenges. Exp Gerontol 2006, 41:1040-5. (Pubitemid 44821688)
    • (2006) Experimental Gerontology , vol.41 , Issue.10 , pp. 1040-1045
    • Golden, T.R.1    Hubbard, A.2    Melov, S.3
  • 53
    • 84864622015 scopus 로고    scopus 로고
    • Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways
    • Shore DE, Carr CE, Ruvkun G: Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways. PLoS Genet 2012, 8:e1002792.
    • (2012) PLoS Genet , vol.8
    • Shore, D.E.1    Carr, C.E.2    Ruvkun, G.3
  • 54
    • 78650944949 scopus 로고    scopus 로고
    • The cell-non-autonomous nature of electron transport chain-mediated longevity
    • Durieux J, Wolff S, Dillin A: The cell-non-autonomous nature of electron transport chain-mediated longevity. Cell 2011, 144:79-91.
    • (2011) Cell , vol.144 , pp. 79-91
    • Durieux, J.1    Wolff, S.2    Dillin, A.3
  • 55
    • 84870166429 scopus 로고    scopus 로고
    • The unfolded protein response in secretory cell function
    • Moore KA, Hollien J: The unfolded protein response in secretory cell function. Annu Rev Genet 2012, 46:165-83.
    • (2012) Annu Rev Genet , vol.46 , pp. 165-183
    • Moore, K.A.1    Hollien, J.2
  • 56
    • 0017782437 scopus 로고
    • Evolution of ageing
    • Kirkwood TB: Evolution of ageing. Nature 1977, 270:301-4.
    • (1977) Nature , vol.270 , pp. 301-304
    • Kirkwood, T.B.1
  • 57
    • 84873633910 scopus 로고    scopus 로고
    • Genetics of longevity in model organisms: Debates and paradigm shifts
    • Gems D, Partridge L: Genetics of longevity in model organisms: debates and paradigm shifts. Annu Rev Physiol 2013, 75: 621-44.
    • (2013) Annu Rev Physiol , vol.75 , pp. 621-644
    • Gems, D.1    Partridge, L.2
  • 58
    • 80053312481 scopus 로고    scopus 로고
    • Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans
    • Lapierre LR, Gelino S, Meléndez A, Hansen M: Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans. Curr Biol 2011, 21:1507-14.
    • (2011) Curr Biol , vol.21 , pp. 1507-1514
    • Lapierre, L.R.1    Gelino, S.2    Meléndez, A.3    Hansen, M.4
  • 59
    • 76249101649 scopus 로고    scopus 로고
    • The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity
    • Alper S, McElwee MK, Apfeld J, Lackford B, Freedman JH, Schwartz DA: The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity. J Biol Chem 2010, 285:1822-8.
    • (2010) J Biol Chem , vol.285 , pp. 1822-1828
    • Alper, S.1    McElwee, M.K.2    Apfeld, J.3    Lackford, B.4    Freedman, J.H.5    Schwartz, D.A.6
  • 60
    • 0037127026 scopus 로고    scopus 로고
    • Regulation of life-span by germ-line stem cells in Caenorhabditis elegans
    • DOI 10.1126/science.1065768
    • Arantes-Oliveira N, Apfeld J, Dillin A, Kenyon C: Regulation of lifespan by germ-line stem cells in Caenorhabditis elegans. Science 2002, 295:502-5. (Pubitemid 34101641)
    • (2002) Science , vol.295 , Issue.5554 , pp. 502-505
    • Arantes-Oliveira, N.1    Apfeld, J.2    Dillin, A.3    Kenyon, C.4
  • 61
    • 0033609291 scopus 로고    scopus 로고
    • Signals from the reproductive system regulate the lifespan of C. elegans
    • DOI 10.1038/20694
    • Hsin H, Kenyon C: Signals from the reproductive system regulate the lifespan of C. elegans. Nature 1999, 399:362-6. (Pubitemid 29318134)
    • (1999) Nature , vol.399 , Issue.6734 , pp. 362-366
    • Hsin, H.1    Kenyon, C.2
  • 62
    • 84872143888 scopus 로고    scopus 로고
    • Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: Roles for GATA factors and lipid gene regulators
    • Zhang P, Judy M, Lee S, Kenyon C: Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators. Cell Metab 2013, 17:85-100.
    • (2013) Cell Metab , vol.17 , pp. 85-100
    • Zhang, P.1    Judy, M.2    Lee, S.3    Kenyon, C.4
  • 63
    • 80052137410 scopus 로고    scopus 로고
    • Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins
    • Prahlad V, Morimoto RI: Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins. Proc Natl Acad Sci USA 2011, 108:14204-9.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 14204-14209
    • Prahlad, V.1    Morimoto, R.I.2


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