-
1
-
-
84878864199
-
The Hallmarks of Aging
-
López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G: The Hallmarks of Aging. Cell 2013, 153:1194-217.
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
López-Otín, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
2
-
-
44849094781
-
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
-
Morimoto RI: Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging. Genes Dev 2008, 22:1427-38.
-
(2008)
Genes Dev
, vol.22
, pp. 1427-1438
-
-
Morimoto, R.I.1
-
3
-
-
77956795163
-
Widespread protein aggregation as an inherent part of aging in C. elegans
-
Della David C, Ollikainen N, Trinidad JC, Cary MP, Burlingame AL, Kenyon C: Widespread protein aggregation as an inherent part of aging in C. elegans. PLoS Biol 2010, 8:e1000450.
-
(2010)
PLoS Biol
, vol.8
-
-
Della David, C.1
Ollikainen, N.2
Trinidad, J.C.3
Cary, M.P.4
Burlingame, A.L.5
Kenyon, C.6
-
4
-
-
84866272849
-
Quantitative in vivo redox sensors uncover oxidative stress as an early event in life
-
Knoefler D, Thamsen M, Koniczek M, Niemuth NJ, Diederich A, Jakob U: Quantitative in vivo redox sensors uncover oxidative stress as an early event in life. Mol Cell 2012, 47:767-76.
-
(2012)
Mol Cell
, vol.47
, pp. 767-776
-
-
Knoefler, D.1
Thamsen, M.2
Koniczek, M.3
Niemuth, N.J.4
Diederich, A.5
Jakob, U.6
-
5
-
-
84878118233
-
Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
-
Rana A, Rera M, Walker DW: Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan. Proc Natl Acad Sci USA 2013, 110:8638-43.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 8638-8643
-
-
Rana, A.1
Rera, M.2
Walker, D.W.3
-
6
-
-
78650918920
-
FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
-
Demontis F, Perrimon N: FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell 2010, 143:813-25.
-
(2010)
Cell
, vol.143
, pp. 813-825
-
-
Demontis, F.1
Perrimon, N.2
-
7
-
-
84855823950
-
Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan
-
Reis-Rodrigues P, Czerwieniec G, Peters TW, Evani US, Alavez S, Gaman EA, Vantipalli M, Mooney SD, Gibson BW, Lithgow GJ, Hughes RE: Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan. Aging Cell 2012, 11:120-7.
-
(2012)
Aging Cell
, vol.11
, pp. 120-127
-
-
Reis-Rodrigues, P.1
Czerwieniec, G.2
Peters, T.W.3
Evani, U.S.4
Alavez, S.5
Gaman, E.A.6
Vantipalli, M.7
Mooney, S.D.8
Gibson, B.W.9
Lithgow, G.J.10
Hughes, R.E.11
-
8
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
DOI 10.1126/science.1141448
-
Balch WE, Morimoto RI, Dillin A, Kelly JW: Adapting proteostasis for disease intervention. Science 2008, 319:916-9. (Pubitemid 351263754)
-
(2008)
Science
, vol.319
, Issue.5865
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
-
9
-
-
70349266064
-
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
-
Ben-Zvi A, Miller EA, Morimoto RI: Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging. Proc Natl Acad Sci USA 2009, 106:14914-9.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14914-14919
-
-
Ben-Zvi, A.1
Miller, E.A.2
Morimoto, R.I.3
-
11
-
-
33847251514
-
Genetic and pharmacological factors that influence reproductive aging in nematodes
-
Hughes SE, Evason K, Xiong C, Kornfeld K: Genetic and pharmacological factors that influence reproductive aging in nematodes. PLoS Genet 2007, 3:e25.
-
(2007)
PLoS Genet
, vol.3
-
-
Hughes, S.E.1
Evason, K.2
Xiong, C.3
Kornfeld, K.4
-
12
-
-
84862848780
-
Ribosome-associated chaperones as key players in proteostasis
-
Preissler S, Deuerling E: Ribosome-associated chaperones as key players in proteostasis. Trends Biochem Sci 2012, 37:274-83.
-
(2012)
Trends Biochem Sci
, vol.37
, pp. 274-283
-
-
Preissler, S.1
Deuerling, E.2
-
13
-
-
84878658572
-
The nascent polypeptide-associated complex is a key regulator of proteostasis
-
Kirstein-Miles J, Scior A, Deuerling E, Morimoto RI: The nascent polypeptide-associated complex is a key regulator of proteostasis. EMBO J 2013, 32:1451-68.
-
(2013)
EMBO J
, vol.32
, pp. 1451-1468
-
-
Kirstein-Miles, J.1
Scior, A.2
Deuerling, E.3
Morimoto, R.I.4
-
14
-
-
0038701745
-
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
-
DOI 10.1126/science.1083701
-
Hsu A, Murphy CT, Kenyon C: Regulation of aging and agerelated disease by DAF-16 and heat-shock factor. Science 2003, 300:1142-5. (Pubitemid 36583098)
-
(2003)
Science
, vol.300
, Issue.5622
, pp. 1142-1145
-
-
Hsu, A.-L.1
Murphy, C.T.2
Kenyon, C.3
-
15
-
-
79953231709
-
A longer and healthier life with TOR down-regulation: Genetics and drugs
-
Bjedov I, Partridge L: A longer and healthier life with TOR down-regulation: genetics and drugs. Biochem Soc Trans 2011, 39:460-5.
-
(2011)
Biochem Soc Trans
, vol.39
, pp. 460-465
-
-
Bjedov, I.1
Partridge, L.2
-
16
-
-
84878741907
-
Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse
-
Geiger T, Velic A, Macek B, Lundberg E, Kampf C, Nagaraj N, Uhlen M, Cox J, Mann M: Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse. Mol Cell Proteomics 2013, 12:1709-22.
-
(2013)
Mol Cell Proteomics
, vol.12
, pp. 1709-1722
-
-
Geiger, T.1
Velic, A.2
Macek, B.3
Lundberg, E.4
Kampf, C.5
Nagaraj, N.6
Uhlen, M.7
Cox, J.8
Mann, M.9
-
17
-
-
65649115267
-
Recognition and processing of ubiquitin-protein conjugates by the proteasome
-
Finley D: Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu Rev Biochem 2009, 78:477-513.
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 477-513
-
-
Finley, D.1
-
18
-
-
84883750565
-
Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging
-
Tsakiri EN, Sykiotis GP, Papassideri IS, Terpos E, Dimopoulos MA, Gorgoulis VG, Bohmann D, Trougakos IP: Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging. Aging Cell 2013, 12:802-13.
-
(2013)
Aging Cell
, vol.12
, pp. 802-813
-
-
Tsakiri, E.N.1
Sykiotis, G.P.2
Papassideri, I.S.3
Terpos, E.4
Dimopoulos, M.A.5
Gorgoulis, V.G.6
Bohmann, D.7
Trougakos, I.P.8
-
19
-
-
84879721350
-
REGg deficiency promotes premature aging via the casein kinase 1 pathway
-
Li L, Zhao D, Wei H, Yao L, Dang Y, Amjad A, Xu J, Liu J, Guo L, Li D, Li Z, Di Zuo, Zhang Y, Liu J, Huang S, Jia C, Wang L, Wang Y, Xie Y, Luo J, Zhang B, Luo H, Donehower LA, Moses RE, Xiao J, O'Malley BW, Li X: REGg deficiency promotes premature aging via the casein kinase 1 pathway. Proc Natl Acad Sci USA 2013, 110:11005-10.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 11005-11010
-
-
Li, L.1
Zhao, D.2
Wei, H.3
Yao, L.4
Dang, Y.5
Amjad, A.6
Xu, J.7
Liu, J.8
Guo, L.9
Li, D.10
Li, Z.11
Zuo, D.12
Zhang, Y.13
Liu, J.14
Huang, S.15
Jia, C.16
Wang, L.17
Wang, Y.18
Xie, Y.19
Luo, J.20
Zhang, B.21
Luo, H.22
Donehower, L.A.23
Moses, R.E.24
Xiao, J.25
O'Malley, B.W.26
Li, X.27
more..
-
20
-
-
77953020414
-
A photoconvertible reporter of the ubiquitin-proteasome system in vivo
-
Hamer G, Matilainen O, Holmberg CI: A photoconvertible reporter of the ubiquitin-proteasome system in vivo. Nat Methods 2010, 7:473-8.
-
(2010)
Nat Methods
, vol.7
, pp. 473-478
-
-
Hamer, G.1
Matilainen, O.2
Holmberg, C.I.3
-
21
-
-
79961023008
-
EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan
-
Liu G, Rogers J, Murphy CT, Rongo C: EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan. EMBO J 2011, 30:2990-3003.
-
(2011)
EMBO J
, vol.30
, pp. 2990-3003
-
-
Liu, G.1
Rogers, J.2
Murphy, C.T.3
Rongo, C.4
-
22
-
-
79955366725
-
A screenable in vivo assay to study proteostasis networks in Caenorhabditis elegans
-
Segref A, Torres S, Hoppe T: A screenable in vivo assay to study proteostasis networks in Caenorhabditis elegans. Genetics 2011, 187:1235-40.
-
(2011)
Genetics
, vol.187
, pp. 1235-1240
-
-
Segref, A.1
Torres, S.2
Hoppe, T.3
-
23
-
-
0037167855
-
Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans
-
DOI 10.1038/nature01135
-
Herndon LA, Schmeissner PJ, Dudaronek JM, Brown PA, Listner KM, Sakano Y, Paupard MC, Hall DH, Driscoll M: Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 2002, 419:808-14. (Pubitemid 35238561)
-
(2002)
Nature
, vol.419
, Issue.6909
, pp. 808-814
-
-
Herndon, L.A.1
Schmeissner, P.J.2
Dudaronek, J.M.3
Brown, P.A.4
Listner, K.M.5
Sakano, Y.6
Paupard, M.C.7
Hall, D.H.8
Driscoll, M.9
-
24
-
-
84883477931
-
Functional aging in the nervous system contributes to age-dependent motor activity decline in C. elegans
-
Liu J, Zhang B, Lei H, Feng Z, Liu J, Hsu A, Xu XZS: Functional aging in the nervous system contributes to age-dependent motor activity decline in C. elegans. Cell Metab 2013, 18:392-402.
-
(2013)
Cell Metab
, vol.18
, pp. 392-402
-
-
Liu, J.1
Zhang, B.2
Lei, H.3
Feng, Z.4
Liu, J.5
Hsu, A.6
Xu, X.Z.S.7
-
25
-
-
59449095881
-
Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process
-
Tonoki A, Kuranaga E, Tomioka T, Hamazaki J, Murata S, Tanaka K, Miura M: Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process. Mol Cell Biol 2009, 29:1095-106.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 1095-1106
-
-
Tonoki, A.1
Kuranaga, E.2
Tomioka, T.3
Hamazaki, J.4
Murata, S.5
Tanaka, K.6
Miura, M.7
-
26
-
-
0034087369
-
Decreased levels of proteasome activity and proteasome expression in aging spinal cord
-
DOI 10.1016/S0306-4522(00)00067-1, PII S0306452200000671
-
Keller JN, Huang FF, Markesbery WR: Decreased levels of proteasome activity and proteasome expression in aging spinal cord. Neuroscience 2000, 98:149-56. (Pubitemid 30349153)
-
(2000)
Neuroscience
, vol.98
, Issue.1
, pp. 149-156
-
-
Keller, J.N.1
Huang, F.F.2
Markesbery, W.R.3
-
27
-
-
67651004289
-
A conserved ubiquitination pathway determines longevity in response to diet restriction
-
Carrano AC, Liu Z, Dillin A, Hunter T: A conserved ubiquitination pathway determines longevity in response to diet restriction. Nature 2009, 460:396-9.
-
(2009)
Nature
, vol.460
, pp. 396-399
-
-
Carrano, A.C.1
Liu, Z.2
Dillin, A.3
Hunter, T.4
-
28
-
-
0033792614
-
Fibroblast cultures from healthy centenarians have an active proteasome
-
Chondrogianni N, Petropoulos I, Franceschi C, Friguet B, Gonos ES: Fibroblast cultures from healthy centenarians have an active proteasome. Exp Gerontol 2000, 35:721-8.
-
(2000)
Exp Gerontol
, vol.35
, pp. 721-728
-
-
Chondrogianni, N.1
Petropoulos, I.2
Franceschi, C.3
Friguet, B.4
Gonos, E.S.5
-
29
-
-
80053445278
-
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae
-
Kruegel U, Robison B, Dange T, Kahlert G, Delaney JR, Kotireddy S, Tsuchiya M, Tsuchiyama S, Murakami CJ, Schleit J, Sutphin G, Carr D, Tar K, Dittmar G, Kaeberlein M, Kennedy BK, Schmidt M: Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae. PLoS Genet 2011, 7:e1002253.
-
(2011)
PLoS Genet
, vol.7
-
-
Kruegel, U.1
Robison, B.2
Dange, T.3
Kahlert, G.4
Delaney, J.R.5
Kotireddy, S.6
Tsuchiya, M.7
Tsuchiyama, S.8
Murakami, C.J.9
Schleit, J.10
Sutphin, G.11
Carr, D.12
Tar, K.13
Dittmar, G.14
Kaeberlein, M.15
Kennedy, B.K.16
Schmidt, M.17
-
30
-
-
62549088648
-
Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat
-
Pérez VI, Buffenstein R, Masamsetti V, Leonard S, Salmon AB, Mele J, Andziak B, Yang T, Edrey Y, Friguet B, Ward W, Richardson A, Chaudhuri A: Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. Proc Natl Acad Sci USA 2009, 106:3059-64.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3059-3064
-
-
Pérez, V.I.1
Buffenstein, R.2
Masamsetti, V.3
Leonard, S.4
Salmon, A.B.5
Mele, J.6
Andziak, B.7
Yang, T.8
Edrey, Y.9
Friguet, B.10
Ward, W.11
Richardson, A.12
Chaudhuri, A.13
-
31
-
-
84866182143
-
RPN-6 determines C. elegans longevity under proteotoxic stress conditions
-
Vilchez D, Morantte I, Liu Z, Douglas PM, Merkwirth C, Rodrigues APC, Manning G, Dillin A: RPN-6 determines C. elegans longevity under proteotoxic stress conditions. Nature 2012, 489:263-8.
-
(2012)
Nature
, vol.489
, pp. 263-268
-
-
Vilchez, D.1
Morantte, I.2
Liu, Z.3
Douglas, P.M.4
Merkwirth, C.5
Rodrigues, A.P.C.6
Manning, G.7
Dillin, A.8
-
34
-
-
79955631150
-
Autophagy in the cellular energetic balance
-
Singh R, Cuervo AM: Autophagy in the cellular energetic balance. Cell Metab 2011, 13:495-504.
-
(2011)
Cell Metab
, vol.13
, pp. 495-504
-
-
Singh, R.1
Cuervo, A.M.2
-
35
-
-
77954955686
-
Heat shock factors: Integrators of cell stress, development and lifespan
-
Akerfelt M, Morimoto RI, Sistonen L: Heat shock factors: integrators of cell stress, development and lifespan. Nat Rev Mol Cell Biol 2010, 11:545-55.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 545-555
-
-
Akerfelt, M.1
Morimoto, R.I.2
Sistonen, L.3
-
36
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
Walter P, Ron D: The unfolded protein response: from stress pathway to homeostatic regulation. Science 2011, 334:1081-6.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
37
-
-
77953012548
-
Stress-activated cap'n'collar transcription factors in aging and human disease
-
Sykiotis GP, Bohmann D: Stress-activated cap'n'collar transcription factors in aging and human disease. Sci Signal 2010, 3:re3.
-
(2010)
Sci Signal
, vol.3
-
-
Sykiotis, G.P.1
Bohmann, D.2
-
38
-
-
77950200010
-
The genetics of ageing
-
Kenyon CJ: The genetics of ageing. Nature 2010, 464:504-12.
-
(2010)
Nature
, vol.464
, pp. 504-512
-
-
Kenyon, C.J.1
-
39
-
-
84877309346
-
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity
-
Riedel CG, Dowen RH, Lourenco GF, Kirienko NV, Heimbucher T, West JA, Bowman SK, Kingston RE, Dillin A, Asara JM, Ruvkun G: DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity. Nat Cell Biol 2013, 15:491-501.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 491-501
-
-
Riedel, C.G.1
Dowen, R.H.2
Lourenco, G.F.3
Kirienko, N.V.4
Heimbucher, T.5
West, J.A.6
Bowman, S.K.7
Kingston, R.E.8
Dillin, A.9
Asara, J.M.10
Ruvkun, G.11
-
40
-
-
84879602902
-
Evaluating and responding to mitochondrial dysfunction: The mitochondrial unfoldedprotein response and beyond
-
Haynes CM, Fiorese CJ, Lin Y: Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfoldedprotein response and beyond. Trends Cell Biol 2013, 23:311-8.
-
(2013)
Trends Cell Biol
, vol.23
, pp. 311-318
-
-
Haynes, C.M.1
Fiorese, C.J.2
Lin, Y.3
-
41
-
-
77953091249
-
Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity
-
Henis-Korenblit S, Zhang P, Hansen M, McCormick M, Lee S, Cary M, Kenyon C: Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity. Proc Natl Acad Sci USA 2010, 107:9730-5.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 9730-9735
-
-
Henis-Korenblit, S.1
Zhang, P.2
Hansen, M.3
McCormick, M.4
Lee, S.5
Cary, M.6
Kenyon, C.7
-
42
-
-
0742323000
-
Regulation of Longevity in Caenorhabditis elegans by Heat Shock Factor and Molecular Chaperones
-
DOI 10.1091/mbc.E03-07-0532
-
Morley JF, Morimoto RI: Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones. Mol Biol Cell 2004, 15:657-64. (Pubitemid 38146482)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.2
, pp. 657-664
-
-
Morley, J.F.1
Morimoto, R.I.2
-
43
-
-
84879343155
-
XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity
-
Taylor RC, Dillin A: XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity. Cell 2013, 153:1435-47.
-
(2013)
Cell
, vol.153
, pp. 1435-1447
-
-
Taylor, R.C.1
Dillin, A.2
-
44
-
-
40849118472
-
Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans
-
DOI 10.1016/j.cell.2008.01.030, PII S009286740800130X
-
Tullet JMA, Hertweck M, An JH, Baker J, Hwang JY, Liu S, Oliveira RP, Baumeister R, Blackwell TK: Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell 2008, 132:1025-38. (Pubitemid 351391953)
-
(2008)
Cell
, vol.132
, Issue.6
, pp. 1025-1038
-
-
Tullet, J.M.A.1
Hertweck, M.2
An, J.H.3
Baker, J.4
Hwang, J.Y.5
Liu, S.6
Oliveira, R.P.7
Baumeister, R.8
Blackwell, T.K.9
-
45
-
-
84880514122
-
Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes
-
Rahman MM, Sykiotis GP, Nishimura M, Bodmer R, Bohmann D: Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes. Aging Cell 2013, 12:554-62.
-
(2013)
Aging Cell
, vol.12
, pp. 554-562
-
-
Rahman, M.M.1
Sykiotis, G.P.2
Nishimura, M.3
Bodmer, R.4
Bohmann, D.5
-
46
-
-
60749101582
-
Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1
-
Westerheide SD, Anckar J, Stevens SM, Sistonen L, Morimoto RI: Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1. Science 2009, 323:1063-6.
-
(2009)
Science
, vol.323
, pp. 1063-1066
-
-
Westerheide, S.D.1
Anckar, J.2
Stevens, S.M.3
Sistonen, L.4
Morimoto, R.I.5
-
47
-
-
0025821986
-
Concomitant decline in heat-induced hyperthermia and HSP70 mRNA expression in aged rats
-
Blake MJ, Fargnoli J, Gershon D, Holbrook NJ: Concomitant decline in heat-induced hyperthermia and HSP70 mRNA expression in aged rats. Am J Physiol 1991, 260:R663-7.
-
(1991)
Am J Physiol
, vol.260
-
-
Blake, M.J.1
Fargnoli, J.2
Gershon, D.3
Holbrook, N.J.4
-
48
-
-
84883767608
-
Germline stem cell arrest inhibits the collapse of somatic proteostasis early in Caenorhabditis elegans adulthood
-
Shemesh N, Shai N, Ben-Zvi A: Germline stem cell arrest inhibits the collapse of somatic proteostasis early in Caenorhabditis elegans adulthood. Aging Cell 2013, 12:814-22.
-
(2013)
Aging Cell
, vol.12
, pp. 814-822
-
-
Shemesh, N.1
Shai, N.2
Ben-Zvi, A.3
-
49
-
-
0025998329
-
Stress-induced heat shock protein 70 expression in adrenal cortex: An adrenocorticotropic hormone-sensitive, age-dependent response
-
Blake MJ, Udelsman R, Feulner GJ, Norton DD, Holbrook NJ: Stress-induced heat shock protein 70 expression in adrenal cortex: an adrenocorticotropic hormone-sensitive, age-dependent response. Proc Natl Acad Sci USA 1991, 88:9873-7. (Pubitemid 21915736)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.21
, pp. 9873-9877
-
-
Blake, M.J.1
Udelsman, R.2
Feulner, G.J.3
Norton, D.D.4
Holbrook, N.J.5
-
50
-
-
33847266842
-
Posteclosion decline in 'knock-down' thermal resistance and reduced effect of heat hardening in Drosophila melanogaster
-
Pappas C, Hyde D, Bowler K, Loeschcke V, Sørensen JG: Posteclosion decline in 'knock-down' thermal resistance and reduced effect of heat hardening in Drosophila melanogaster. Comp Biochem Physiol., Part A Mol Integr Physiol 2007, 146:355-9.
-
(2007)
Comp Biochem Physiol., Part A Mol Integr Physiol
, vol.146
, pp. 355-359
-
-
Pappas, C.1
Hyde, D.2
Bowler, K.3
Loeschcke, V.4
Sørensen, J.G.5
-
51
-
-
33751420477
-
Microarray analysis of variation in individual aging C. elegans: Approaches and challenges
-
DOI 10.1016/j.exger.2006.06.034, PII S0531556506002166
-
Golden TR, Hubbard A, Melov S: Microarray analysis of variation in individual aging C. elegans: approaches and challenges. Exp Gerontol 2006, 41:1040-5. (Pubitemid 44821688)
-
(2006)
Experimental Gerontology
, vol.41
, Issue.10
, pp. 1040-1045
-
-
Golden, T.R.1
Hubbard, A.2
Melov, S.3
-
52
-
-
0037125942
-
Transcriptional profile of aging in C. elegans
-
Lund J, Tedesco P, Duke K, Wang J, Kim SK, Johnson TE: Transcriptional profile of aging in C. elegans. Curr Biol 2002, 12:1566-73.
-
(2002)
Curr Biol
, vol.12
, pp. 1566-1573
-
-
Lund, J.1
Tedesco, P.2
Duke, K.3
Wang, J.4
Kim, S.K.5
Johnson, T.E.6
-
53
-
-
84864622015
-
Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways
-
Shore DE, Carr CE, Ruvkun G: Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways. PLoS Genet 2012, 8:e1002792.
-
(2012)
PLoS Genet
, vol.8
-
-
Shore, D.E.1
Carr, C.E.2
Ruvkun, G.3
-
54
-
-
78650944949
-
The cell-non-autonomous nature of electron transport chain-mediated longevity
-
Durieux J, Wolff S, Dillin A: The cell-non-autonomous nature of electron transport chain-mediated longevity. Cell 2011, 144:79-91.
-
(2011)
Cell
, vol.144
, pp. 79-91
-
-
Durieux, J.1
Wolff, S.2
Dillin, A.3
-
55
-
-
84870166429
-
The unfolded protein response in secretory cell function
-
Moore KA, Hollien J: The unfolded protein response in secretory cell function. Annu Rev Genet 2012, 46:165-83.
-
(2012)
Annu Rev Genet
, vol.46
, pp. 165-183
-
-
Moore, K.A.1
Hollien, J.2
-
56
-
-
0017782437
-
Evolution of ageing
-
Kirkwood TB: Evolution of ageing. Nature 1977, 270:301-4.
-
(1977)
Nature
, vol.270
, pp. 301-304
-
-
Kirkwood, T.B.1
-
57
-
-
84873633910
-
Genetics of longevity in model organisms: Debates and paradigm shifts
-
Gems D, Partridge L: Genetics of longevity in model organisms: debates and paradigm shifts. Annu Rev Physiol 2013, 75: 621-44.
-
(2013)
Annu Rev Physiol
, vol.75
, pp. 621-644
-
-
Gems, D.1
Partridge, L.2
-
58
-
-
80053312481
-
Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans
-
Lapierre LR, Gelino S, Meléndez A, Hansen M: Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans. Curr Biol 2011, 21:1507-14.
-
(2011)
Curr Biol
, vol.21
, pp. 1507-1514
-
-
Lapierre, L.R.1
Gelino, S.2
Meléndez, A.3
Hansen, M.4
-
59
-
-
76249101649
-
The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity
-
Alper S, McElwee MK, Apfeld J, Lackford B, Freedman JH, Schwartz DA: The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity. J Biol Chem 2010, 285:1822-8.
-
(2010)
J Biol Chem
, vol.285
, pp. 1822-1828
-
-
Alper, S.1
McElwee, M.K.2
Apfeld, J.3
Lackford, B.4
Freedman, J.H.5
Schwartz, D.A.6
-
60
-
-
0037127026
-
Regulation of life-span by germ-line stem cells in Caenorhabditis elegans
-
DOI 10.1126/science.1065768
-
Arantes-Oliveira N, Apfeld J, Dillin A, Kenyon C: Regulation of lifespan by germ-line stem cells in Caenorhabditis elegans. Science 2002, 295:502-5. (Pubitemid 34101641)
-
(2002)
Science
, vol.295
, Issue.5554
, pp. 502-505
-
-
Arantes-Oliveira, N.1
Apfeld, J.2
Dillin, A.3
Kenyon, C.4
-
61
-
-
0033609291
-
Signals from the reproductive system regulate the lifespan of C. elegans
-
DOI 10.1038/20694
-
Hsin H, Kenyon C: Signals from the reproductive system regulate the lifespan of C. elegans. Nature 1999, 399:362-6. (Pubitemid 29318134)
-
(1999)
Nature
, vol.399
, Issue.6734
, pp. 362-366
-
-
Hsin, H.1
Kenyon, C.2
-
62
-
-
84872143888
-
Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: Roles for GATA factors and lipid gene regulators
-
Zhang P, Judy M, Lee S, Kenyon C: Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators. Cell Metab 2013, 17:85-100.
-
(2013)
Cell Metab
, vol.17
, pp. 85-100
-
-
Zhang, P.1
Judy, M.2
Lee, S.3
Kenyon, C.4
-
63
-
-
80052137410
-
Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins
-
Prahlad V, Morimoto RI: Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins. Proc Natl Acad Sci USA 2011, 108:14204-9.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 14204-14209
-
-
Prahlad, V.1
Morimoto, R.I.2
|