-
1
-
-
79955663580
-
Regulated intramembrane proteolysis: lessons from amyloid precursor protein processing
-
Lichtenthaler SF, Haass C, Steiner H. 2011. Regulated intramembrane proteolysis: lessons from amyloid precursor protein processing. J. Neurochem. 117:779-796. http://dx.doi.org/10.1111/j.1471-4159.2011.07248.x.
-
(2011)
J. Neurochem.
, vol.117
, pp. 779-796
-
-
Lichtenthaler, S.F.1
Haass, C.2
Steiner, H.3
-
2
-
-
0036777494
-
Intramembrane proteolysis controls diverse signalling pathways throughout evolution
-
Urban S, Freeman M. 2002. Intramembrane proteolysis controls diverse signalling pathways throughout evolution. Curr. Opin. Genet. Dev. 12: 512-518. http://dx.doi.org/10.1016/S0959-437X(02)00334-9.
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 512-518
-
-
Urban, S.1
Freeman, M.2
-
3
-
-
84885092137
-
Mechanism, specificity, and physiology of signal peptide peptidase (SPP) and SPP-like proteases
-
Voss M, Schröder B, Fluhrer R. 2013. Mechanism, specificity, and physiology of signal peptide peptidase (SPP) and SPP-like proteases. Biochim. Biophys. Acta 1828:2828-2839. http://dx.doi.org/10.1016/j.bbamem.2013.03.033.
-
(2013)
Biochim. Biophys. Acta
, vol.1828
, pp. 2828-2839
-
-
Voss, M.1
Schröder, B.2
Fluhrer, R.3
-
4
-
-
84874524255
-
The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain
-
Schneppenheim J, Dressel R, Hüttl S, Lüllmann-Rauch R, Engelke M, Dittmann K, Wienands J, Eskelinen EL, Hermans-Borgmeyer I, Fluhrer R, Saftig P, Schröder B. 2013. The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain. J. Exp. Med. 210:41-58. http://dx.doi.org/10.1084/jem.20121069.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 41-58
-
-
Schneppenheim, J.1
Dressel, R.2
Hüttl, S.3
Lüllmann-Rauch, R.4
Engelke, M.5
Dittmann, K.6
Wienands, J.7
Eskelinen, E.L.8
Hermans-Borgmeyer, I.9
Fluhrer, R.10
Saftig, P.11
Schröder, B.12
-
5
-
-
84874516142
-
The intramembrane protease Sppl2a is required for B cell andDCdevelopment and survival via cleavage of the invariant chain
-
Beisner DR, Langerak P, Parker AE, Dahlberg C, Otero FJ, Sutton SE, Poirot L, Barnes W, Young MA, Niessen S, Wiltshire T, Bodendorf U, Martoglio B, Cravatt B, Cooke MP. 2013. The intramembrane protease Sppl2a is required for B cell andDCdevelopment and survival via cleavage of the invariant chain. J. Exp. Med. 210:23-30. http://dx.doi.org/10.1084/jem.20121072.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 23-30
-
-
Beisner, D.R.1
Langerak, P.2
Parker, A.E.3
Dahlberg, C.4
Otero, F.J.5
Sutton, S.E.6
Poirot, L.7
Barnes, W.8
Young, M.A.9
Niessen, S.10
Wiltshire, T.11
Bodendorf, U.12
Martoglio, B.13
Cravatt, B.14
Cooke, M.P.15
-
6
-
-
84874520391
-
B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A
-
Bergmann H, Yabas M, Short A, Miosge L, Barthel N, Teh CE, Roots CM, Bull-Jeelall KRY, Horikawa K, Whittle B, Balakishnan B, Sjollema G, Bertram EM, MacKay F, Rimmer AJ, Cornall RJ, Field MA, Andrews TD, Goodnow CC, Enders A. 2013. B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A. J. Exp. Med. 210:31-40. http://dx.doi.org/10.1084/jem.20121076.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 31-40
-
-
Bergmann, H.1
Yabas, M.2
Short, A.3
Miosge, L.4
Barthel, N.5
Teh, C.E.6
Roots, C.M.7
Bull-Jeelall, K.R.Y.8
Horikawa, K.9
Whittle, B.10
Balakishnan, B.11
Sjollema, G.12
Bertram, E.M.13
MacKay, F.14
Rimmer, A.J.15
Cornall, R.J.16
Field, M.A.17
Andrews, T.D.18
Goodnow, C.C.19
Enders, A.20
more..
-
7
-
-
82255164138
-
Towards a systems understanding of MHC class I and MHC class II antigen presentation
-
Neefjes J, Jongsma ML, Paul P, Bakke O. 2011. Towards a systems understanding of MHC class I and MHC class II antigen presentation. Nat. Rev. Immunol. 11:823-836. http://dx.doi.org/10.1038/nri3084.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 823-836
-
-
Neefjes, J.1
Jongsma, M.L.2
Paul, P.3
Bakke, O.4
-
8
-
-
27644575670
-
CD74 is a member of the regulated intramembrane proteolysis-processed protein family
-
Becker-Herman S, Arie G, Medvedovsky H, Kerem A, Shachar I. 2005. CD74 is a member of the regulated intramembrane proteolysis-processed protein family. Mol. Biol. Cell 16:5061-5069. http://dx.doi.org/10.1091/mbc. E05-04-0327.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 5061-5069
-
-
Becker-Herman, S.1
Arie, G.2
Medvedovsky, H.3
Kerem, A.4
Shachar, I.5
-
9
-
-
33746618450
-
SPPL2a and SPPL2b promote intramembrane proteolysis of TNFα in activated dendritic cells to trigger IL-12 production
-
Friedmann E, Hauben E, Maylandt K, Schleeger S, Vreugde S, Lichtenthaler SF, Kuhn PH, Stauffer D, Rovelli G, Martoglio B. 2006. SPPL2a and SPPL2b promote intramembrane proteolysis of TNFα in activated dendritic cells to trigger IL-12 production. Nat. Cell Biol. 8:843-848. http://dx.doi.org/10.1038/ncb1440.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 843-848
-
-
Friedmann, E.1
Hauben, E.2
Maylandt, K.3
Schleeger, S.4
Vreugde, S.5
Lichtenthaler, S.F.6
Kuhn, P.H.7
Stauffer, D.8
Rovelli, G.9
Martoglio, B.10
-
10
-
-
33746608185
-
A gamma-secretase-like intramembrane cleavage of TNFα by the GxGD aspartyl protease SPPL2b
-
Fluhrer R, Grammer G, Israel L, Condron MM, Haffner C, Friedmann E, Bohland C, Imhof A, Martoglio B, Teplow DB, Haass C. 2006. A gamma-secretase-like intramembrane cleavage of TNFα by the GxGD aspartyl protease SPPL2b. Nat. Cell Biol. 8:894-896. http://dx.doi.org/10.1038/ncb1450.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 894-896
-
-
Fluhrer, R.1
Grammer, G.2
Israel, L.3
Condron, M.M.4
Haffner, C.5
Friedmann, E.6
Bohland, C.7
Imhof, A.8
Martoglio, B.9
Teplow, D.B.10
Haass, C.11
-
11
-
-
34548040200
-
The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T cells
-
Kirkin V, Cahuzac N, Guardiola-Serrano F, Huault S, Luckerath K, Friedmann E, Novac N, Wels WS, Martoglio B, Hueber AO, Zornig M. 2007. The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T cells. Cell Death. Differ. 14:1678-1687. http://dx.doi.org/10.1038/sj.cdd.4402175.
-
(2007)
Cell Death. Differ.
, vol.14
, pp. 1678-1687
-
-
Kirkin, V.1
Cahuzac, N.2
Guardiola-Serrano, F.3
Huault, S.4
Luckerath, K.5
Friedmann, E.6
Novac, N.7
Wels, W.S.8
Martoglio, B.9
Hueber, A.O.10
Zornig, M.11
-
12
-
-
38349144907
-
Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b
-
Martin L, Fluhrer R, Reiss K, Kremmer E, Saftig P, Haass C. 2008. Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b. J. Biol. Chem. 283:1644-1652. http://dx.doi.org/10.1074/jbc. M706661200.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1644-1652
-
-
Martin, L.1
Fluhrer, R.2
Reiss, K.3
Kremmer, E.4
Saftig, P.5
Haass, C.6
-
13
-
-
84875828276
-
The transferrin receptor-1 membrane stub undergoes intramembrane proteolysis by signal peptide peptidase-like 2b
-
Zahn C, Kaup M, Fluhrer R, Fuchs H. 2013. The transferrin receptor-1 membrane stub undergoes intramembrane proteolysis by signal peptide peptidase-like 2b. FEBS J. 280:1653-1663. http://dx.doi.org/10.1111/febs.12176.
-
(2013)
FEBS J.
, vol.280
, pp. 1653-1663
-
-
Zahn, C.1
Kaup, M.2
Fluhrer, R.3
Fuchs, H.4
-
14
-
-
0038401145
-
Invariant chain, a chain of command
-
Matza D, Kerem A, Shachar I. 2003. Invariant chain, a chain of command. Trends Immunol. 24:264-268. http://dx.doi.org/10.1016/S1471-4906(03)00073-5.
-
(2003)
Trends Immunol.
, vol.24
, pp. 264-268
-
-
Matza, D.1
Kerem, A.2
Shachar, I.3
-
15
-
-
63949088399
-
Signal peptide peptidases: a family of intramembrane-cleaving proteases that cleave type 2 transmembrane proteins
-
Golde TE, Wolfe MS, Greenbaum DC. 2009. Signal peptide peptidases: a family of intramembrane-cleaving proteases that cleave type 2 transmembrane proteins. Semin. Cell Dev. Biol. 20:225-230. http://dx.doi.org/10.1016/j.semcdb.2009.02.003.
-
(2009)
Semin. Cell Dev. Biol.
, vol.20
, pp. 225-230
-
-
Golde, T.E.1
Wolfe, M.S.2
Greenbaum, D.C.3
-
16
-
-
84896502816
-
-
Reference deleted
-
Reference deleted.
-
-
-
-
17
-
-
80053248954
-
Signal-peptide-peptidase-like 2a (SPPL2a) is targeted to lysosomes/late endosomes by a tyrosine motif in its C-terminal tail
-
Behnke J, Schneppenheim J, Koch-Nolte F, Haag F, Saftig P, Schröder B. 2011. Signal-peptide-peptidase-like 2a (SPPL2a) is targeted to lysosomes/late endosomes by a tyrosine motif in its C-terminal tail. FEBS Lett. 585:2951-2957. http://dx.doi.org/10.1016/j.febslet.2011.08.043.
-
(2011)
FEBS Lett.
, vol.585
, pp. 2951-2957
-
-
Behnke, J.1
Schneppenheim, J.2
Koch-Nolte, F.3
Haag, F.4
Saftig, P.5
Schröder, B.6
-
18
-
-
12444285441
-
MIF signal transduction initiated by binding to CD74
-
Leng L, Metz CN, Fang Y, Xu J, Donnelly S, Baugh J, Delohery T, Chen Y, Mitchell RA, Bucala R. 2003. MIF signal transduction initiated by binding to CD74. J. Exp. Med. 197:1467-1476. http://dx.doi.org/10.1084/jem.20030286.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1467-1476
-
-
Leng, L.1
Metz, C.N.2
Fang, Y.3
Xu, J.4
Donnelly, S.5
Baugh, J.6
Delohery, T.7
Chen, Y.8
Mitchell, R.A.9
Bucala, R.10
-
19
-
-
33749508911
-
CD44 is the signaling component of the macrophage migration inhibitory factor- CD74 receptor complex
-
Shi X, Leng L, Wang T, Wang W, Du X, Li J, McDonald C, Chen Z, Murphy JW, Lolis E, Noble P, Knudson W, Bucala R. 2006. CD44 is the signaling component of the macrophage migration inhibitory factor- CD74 receptor complex. Immunity 25:595-606. http://dx.doi.org/10.1016/j.immuni.2006.08.020.
-
(2006)
Immunity
, vol.25
, pp. 595-606
-
-
Shi, X.1
Leng, L.2
Wang, T.3
Wang, W.4
Du, X.5
Li, J.6
McDonald, C.7
Chen, Z.8
Murphy, J.W.9
Lolis, E.10
Noble, P.11
Knudson, W.12
Bucala, R.13
-
20
-
-
69249228563
-
A functional heteromeric MIF receptor formed by CD74 and CXCR4
-
Schwartz V, Lue H, Kraemer S, Korbiel J, Krohn R, Ohl K, Bucala R, Weber C, Bernhagen J. 2009. A functional heteromeric MIF receptor formed by CD74 and CXCR4. FEBS Lett. 583:2749-2757. http://dx.doi.org/10.1016/j.febslet.2009.07.058.
-
(2009)
FEBS Lett.
, vol.583
, pp. 2749-2757
-
-
Schwartz, V.1
Lue, H.2
Kraemer, S.3
Korbiel, J.4
Krohn, R.5
Ohl, K.6
Bucala, R.7
Weber, C.8
Bernhagen, J.9
-
21
-
-
0142259734
-
Macrophage migration inhibitory factor: a regulator of innate immunity
-
Calandra T, Roger T. 2003. Macrophage migration inhibitory factor: a regulator of innate immunity. Nat. Rev. Immunol. 3:791-800. http://dx.doi.org/10.1038/nri1200.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 791-800
-
-
Calandra, T.1
Roger, T.2
-
22
-
-
40949087882
-
Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex
-
Gore Y, Starlets D, Maharshak N, Becker-Herman S, Kaneyuki U, Leng L, Bucala R, Shachar I. 2008. Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex. J. Biol. Chem. 283:2784-2792. http://dx.doi.org/10.1074/jbc. M703265200.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 2784-2792
-
-
Gore, Y.1
Starlets, D.2
Maharshak, N.3
Becker-Herman, S.4
Kaneyuki, U.5
Leng, L.6
Bucala, R.7
Shachar, I.8
-
23
-
-
40949140467
-
Perivascular clusters of dendritic cells provide critical survival signals to B cells in bone marrow niches
-
Sapoznikov A, Pewzner-Jung Y, Kalchenko V, Krauthgamer R, Shachar I, Jung S. 2008. Perivascular clusters of dendritic cells provide critical survival signals to B cells in bone marrow niches. Nat. Immunol. 9:388-395. http://dx.doi.org/10.1038/ni1571.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 388-395
-
-
Sapoznikov, A.1
Pewzner-Jung, Y.2
Kalchenko, V.3
Krauthgamer, R.4
Shachar, I.5
Jung, S.6
-
24
-
-
0346980633
-
Exchangeable gene trap using the Cre/mutated lox system
-
Araki K, Imaizumi T, Sekimoto T, Yoshinobu K, Yoshimuta J, Akizuki M, Miura K, Araki M, Yamamura K. 1999. Exchangeable gene trap using the Cre/mutated lox system. Cell Mol. Biol. 45:737-750.
-
(1999)
Cell Mol. Biol.
, vol.45
, pp. 737-750
-
-
Araki, K.1
Imaizumi, T.2
Sekimoto, T.3
Yoshinobu, K.4
Yoshimuta, J.5
Akizuki, M.6
Miura, K.7
Araki, M.8
Yamamura, K.9
-
25
-
-
21044449884
-
Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette
-
Taniwaki T, Haruna K, Nakamura H, Sekimoto T, Oike Y, Imaizumi T, Saito F, Muta M, Soejima Y, Utoh A, Nakagata N, Araki M, Yamamura K, Araki K. 2005. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Dev. Growth Differ. 47: 163-172. http://dx.doi.org/10.1111/j.1440-169X.2005.00792.x.
-
(2005)
Dev. Growth Differ.
, vol.47
, pp. 163-172
-
-
Taniwaki, T.1
Haruna, K.2
Nakamura, H.3
Sekimoto, T.4
Oike, Y.5
Imaizumi, T.6
Saito, F.7
Muta, M.8
Soejima, Y.9
Utoh, A.10
Nakagata, N.11
Araki, M.12
Yamamura, K.13
Araki, K.14
-
26
-
-
80052701566
-
Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L
-
Savalas LR, Gasnier B, Damme M, Lubke T, Wrocklage C, Debacker C, Jezegou A, Reinheckel T, Hasilik A, Saftig P, Schröder B. 2011. Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L. Biochem. J. 439: 113-128. http://dx.doi.org/10.1042/BJ20110166.
-
(2011)
Biochem. J.
, vol.439
, pp. 113-128
-
-
Savalas, L.R.1
Gasnier, B.2
Damme, M.3
Lubke, T.4
Wrocklage, C.5
Debacker, C.6
Jezegou, A.7
Reinheckel, T.8
Hasilik, A.9
Saftig, P.10
Schröder, B.11
-
27
-
-
0018388062
-
Establishment and characterization of BALB/c lymphoma lines with B cell properties
-
Kim KJ, Kanellopoulos-Langevin C, Merwin RM, Sachs DH, Asofsky R. 1979. Establishment and characterization of BALB/c lymphoma lines with B cell properties. J. Immunol. 122:549-554.
-
(1979)
J. Immunol.
, vol.122
, pp. 549-554
-
-
Kim, K.J.1
Kanellopoulos-Langevin, C.2
Merwin, R.M.3
Sachs, D.H.4
Asofsky, R.5
-
28
-
-
77956646290
-
Molecular characterisation of "transmembrane protein 192" (TMEM192), a novel protein of the lysosomal membrane
-
Schröder B, Wrocklage C, Hasilik A, Saftig P. 2010. Molecular characterisation of "transmembrane protein 192" (TMEM192), a novel protein of the lysosomal membrane. Biol. Chem. 391:695-704. http://dx.doi.org/10.1515/BC.2010.062.
-
(2010)
Biol. Chem.
, vol.391
, pp. 695-704
-
-
Schröder, B.1
Wrocklage, C.2
Hasilik, A.3
Saftig, P.4
-
29
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685. http://dx.doi.org/10.1038/227680a0.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
30
-
-
34248679167
-
-
Tricine-SDS-PAGE
-
Schagger H. 2006. Tricine-SDS-PAGE. Nat. Protoc. 1:16-22. http://dx.doi.org/10.1038/nprot.2006.4.
-
(2006)
Nat. Protoc.
, vol.1
, pp. 16-22
-
-
Schagger, H.1
-
31
-
-
0033012030
-
An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
-
Lutz MB, Kukutsch N, Ogilvie AL, Rossner S, Koch F, Romani N, Schuler G. 1999. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J. Immunol. Methods 223:77-92. http://dx.doi.org/10.1016/S0022-1759(98)00204-X.
-
(1999)
J. Immunol. Methods
, vol.223
, pp. 77-92
-
-
Lutz, M.B.1
Kukutsch, N.2
Ogilvie, A.L.3
Rossner, S.4
Koch, F.5
Romani, N.6
Schuler, G.7
-
32
-
-
0031032648
-
Selective modulation of the major histocompatibility complex class II antigen presentation pathway following B cell receptor ligation and protein kinase C activation
-
Barois N, Forquet F, Davoust J. 1997. Selective modulation of the major histocompatibility complex class II antigen presentation pathway following B cell receptor ligation and protein kinase C activation. J. Biol. Chem. 272:3641-3647. http://dx.doi.org/10.1074/jbc.272.6.3641.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3641-3647
-
-
Barois, N.1
Forquet, F.2
Davoust, J.3
-
33
-
-
0026586892
-
Stimulation of the biosynthesis of lactosamine repeats in glycoproteins in differentiating U937 cells and its suppression in the presence of NH4Cl
-
Radons J, Faber V, Buhrmester H, Volker W, Horejsi V, Hasilik A. 1992. Stimulation of the biosynthesis of lactosamine repeats in glycoproteins in differentiating U937 cells and its suppression in the presence of NH4Cl. Eur. J. Cell Biol. 57:184-192.
-
(1992)
Eur. J. Cell Biol.
, vol.57
, pp. 184-192
-
-
Radons, J.1
Faber, V.2
Buhrmester, H.3
Volker, W.4
Horejsi, V.5
Hasilik, A.6
-
34
-
-
0017698250
-
Human α-N-acetylglucosaminidase. 1. Purification and properties.
-
von Figura K. 1977. Human α-N-acetylglucosaminidase. 1. Purification and properties. Eur. J. Biochem. 80:523-533.
-
(1977)
Eur. J. Biochem
, vol.80
, pp. 523-533
-
-
von Figura, K.1
-
35
-
-
10944270703
-
Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins
-
Friedmann E, Lemberg MK, Weihofen A, Dev Dengler KKU, Rovelli G, Martoglio B. 2004. Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins. J. Biol. Chem. 279:50790-50798. http://dx.doi.org/10.1074/jbc. M407898200.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 50790-50798
-
-
Friedmann, E.1
Lemberg, M.K.2
Weihofen, A.3
Dev Dengler, K.K.U.4
Rovelli, G.5
Martoglio, B.6
-
36
-
-
0029837980
-
Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface
-
Wubbolts R, Fernandez-Borja M, Oomen L, Verwoerd D, Janssen H, Calafat J, Tulp A, Dusseljee S, Neefjes J. 1996. Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface. J. Cell Biol. 135:611-622. http://dx.doi.org/10.1083/jcb.135.3.611.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 611-622
-
-
Wubbolts, R.1
Fernandez-Borja, M.2
Oomen, L.3
Verwoerd, D.4
Janssen, H.5
Calafat, J.6
Tulp, A.7
Dusseljee, S.8
Neefjes, J.9
-
37
-
-
63649164073
-
Trafficking, a key player in regulated intramembrane proteolysis
-
Sannerud R, Annaert W. 2009. Trafficking, a key player in regulated intramembrane proteolysis. Semin. Cell Dev. Biol. 20:183-190. http://dx.doi.org/10.1016/j.semcdb.2008.11.004.
-
(2009)
Semin. Cell Dev. Biol.
, vol.20
, pp. 183-190
-
-
Sannerud, R.1
Annaert, W.2
-
38
-
-
77954232611
-
Transmembrane TNF-alpha: structure, function and interaction with anti- TNF agents
-
Horiuchi T, Mitoma H, Harashima S, Tsukamoto H, Shimoda T. 2010. Transmembrane TNF-alpha: structure, function and interaction with anti- TNF agents. Rheumatology (Oxford) 49:1215-1228. http://dx.doi.org/10.1093/rheumatology/keq031.
-
(2010)
Rheumatology (Oxford)
, vol.49
, pp. 1215-1228
-
-
Horiuchi, T.1
Mitoma, H.2
Harashima, S.3
Tsukamoto, H.4
Shimoda, T.5
-
39
-
-
59049098098
-
BRI2 as a central protein involved in neurodegeneration
-
Tsachaki M, Ghiso J, Efthimiopoulos S. 2008. BRI2 as a central protein involved in neurodegeneration. Biotechnol. J. 3:1548-1554. http://dx.doi.org/10.1002/biot.200800247.
-
(2008)
Biotechnol. J.
, vol.3
, pp. 1548-1554
-
-
Tsachaki, M.1
Ghiso, J.2
Efthimiopoulos, S.3
-
40
-
-
28244456207
-
Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3
-
Krawitz P, Haffner C, Fluhrer R, Steiner H, Schmid B, Haass C. 2005. Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3. J. Biol. Chem. 280:39515-39523. http://dx.doi.org/10.1074/jbc. M501645200.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39515-39523
-
-
Krawitz, P.1
Haffner, C.2
Fluhrer, R.3
Steiner, H.4
Schmid, B.5
Haass, C.6
-
41
-
-
33645105621
-
Presenilin clinical mutations can affect gamma- secretase activity by different mechanisms
-
Bentahir M, Nyabi O, Verhamme J, Tolia A, Horre K, Wiltfang J, Esselmann H, De SB. 2006. Presenilin clinical mutations can affect gamma- secretase activity by different mechanisms. J. Neurochem. 96:732-742. http://dx.doi.org/10.1111/j.1471-4159.2005.03578.x.
-
(2006)
J. Neurochem.
, vol.96
, pp. 732-742
-
-
Bentahir, M.1
Nyabi, O.2
Verhamme, J.3
Tolia, A.4
Horre, K.5
Wiltfang, J.6
Esselmann, H.7
De, S.B.8
-
42
-
-
0037590902
-
Presenilin-1 and presenilin-2 exhibit distinct yet overlapping gamma-secretase activities
-
Lai MT, Chen E, Crouthamel MC, Muzio-Mower J, Xu M, Huang Q, Price E, Register RB, Shi XP, Donoviel DB, Bernstein A, Hazuda D, Gardell SJ, Li YM. 2003. Presenilin-1 and presenilin-2 exhibit distinct yet overlapping gamma-secretase activities. J. Biol. Chem. 278:22475-22481. http://dx.doi.org/10.1074/jbc. M300974200.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22475-22481
-
-
Lai, M.T.1
Chen, E.2
Crouthamel, M.C.3
Muzio-Mower, J.4
Xu, M.5
Huang, Q.6
Price, E.7
Register, R.B.8
Shi, X.P.9
Donoviel, D.B.10
Bernstein, A.11
Hazuda, D.12
Gardell, S.J.13
Li, Y.M.14
-
43
-
-
0030779784
-
Skeletal and CNS defects in presenilin-1-deficient mice
-
Shen J, Bronson RT, Chen DF, Xia W, Selkoe DJ, Tonegawa S. 1997. Skeletal and CNS defects in presenilin-1-deficient mice. Cell 89:629-639. http://dx.doi.org/10.1016/S0092-8674(00)80244-5.
-
(1997)
Cell
, vol.89
, pp. 629-639
-
-
Shen, J.1
Bronson, R.T.2
Chen, D.F.3
Xia, W.4
Selkoe, D.J.5
Tonegawa, S.6
-
44
-
-
13044278313
-
Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency
-
Herreman A, Hartmann D, Annaert W, Saftig P, Craessaerts K, Serneels L, Umans L, Schrijvers V, Checler F, Vanderstichele H, Baekelandt V, Dressel R, Cupers P, Huylebroeck D, Zwijsen A, Van Leuven F, De Strooper B. 1999. Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency. Proc. Natl. Acad. Sci. U. S. A. 96:11872-11877. http://dx.doi.org/10.1073/pnas.96.21.11872.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 11872-11877
-
-
Herreman, A.1
Hartmann, D.2
Annaert, W.3
Saftig, P.4
Craessaerts, K.5
Serneels, L.6
Umans, L.7
Schrijvers, V.8
Checler, F.9
Vanderstichele, H.10
Baekelandt, V.11
Dressel, R.12
Cupers, P.13
Huylebroeck, D.14
Zwijsen, A.15
Van Leuven, F.16
De Strooper, B.17
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