Subcellular localization and activation of ADAM proteases in the context of FasL shedding in T lymphocytes

Molecular Immunology

Volumn 65, Issue 2, 2015, Pages 416-428

  Ebsen, Henriette ^a   Lettau, Marcus ^a   Kabelitz, Dieter ^a   Janssen, Ottmar ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

ADAM proteases; Fas Ligand; Lipid rafts; Proteolysis; Secretory lysosomes; T Lymphocytes

Indexed keywords

ADAM PROTEIN; ADAM10 ENDOPEPTIDASE; ADAM17 PROTEIN; CD3 ANTIGEN; FAS LIGAND; GRANZYME B; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; NCK PROTEIN; PROTEIN KINASE C; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; ADAM10 PROTEIN, HUMAN; CD28 ANTIGEN; FASLG PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; SECRETASE; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIPID RAFT; LYSOSOME; PALMITOYLATION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; CELL LINE; CELL MEMBRANE; CLINICAL TRIAL; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MALE; SECRETORY VESICLE; T LYMPHOCYTE;

ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; ANTIGENS, CD28; ANTIGENS, CD3; CELL LINE; ENZYME ACTIVATION; FAS LIGAND PROTEIN; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LYMPHOCYTE ACTIVATION; LYSOSOMES; MALE; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; PROTEOLYSIS; RECEPTORS, ANTIGEN, T-CELL; SECRETORY VESICLES; T-LYMPHOCYTES;

EID: 84924025819     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2015.02.008     Document Type: Article

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