A decamer duplication in the 3′ region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 9, 2000, Pages 4920-4925

  Vidal, Ruben ^a   Révész, Tamas ^b   Rostagno, Agueda ^a   Kim, Eugene ^a   Holton, Janice L ^b   Bek, Toke ^c   Bojsen Møller, Marie ^c   Braendgaard, Hans ^c   Plant, Gordon ^d   Ghiso, Jorge ^a   Frangione, Blas ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

^d NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PROTEIN;

3' UNTRANSLATED REGION; ALZHEIMER DISEASE; AMYLOIDOSIS; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEMENTIA; DENMARK; FAMILIAL DISEASE; FRAMESHIFT MUTATION; GENE DUPLICATION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; LEPTOMENINX; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; SENILE PLAQUE; STOP CODON;

3' UNTRANSLATED REGIONS; AMINO ACID SEQUENCE; AMYLOID; BASE SEQUENCE; DEMENTIA; DENMARK; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE DUPLICATION; HUMANS; MALE; MOLECULAR SEQUENCE DATA; PEDIGREE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TEMPORAL LOBE;

ATAXIA; HIPPOCAMPUS HIPPOCAMPUS;

EID: 0034712749     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.080076097     Document Type: Article

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