Genetic mouse models of brain ageing and Alzheimer's disease

Pharmacology and Therapeutics

Volumn 142, Issue 2, 2014, Pages 244-257

  Bilkei Gorzo, Andras ^a,b  

^a UNIVERSITY OF BONN   (Germany)

^b NONE   (Germany)

Author keywords

Amyloid plaque; Cognitive ageing; Life span; Neuronal loss; Oxidative load; Translational model validity

Indexed keywords

AMYLOID PRECURSOR PROTEIN; INSULIN; SOMATOMEDIN;

3XTG MOUSE; 5XFAD MOUSE; AGING; ALZHEIMER DISEASE; APP PS1 MOUSE; APP23 MOUSE; BRAIN; CELL STRESS; COGNITIVE DEFECT; EXPERIMENTAL MOUSE; LIFESPAN; MACROMOLECULE; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; TG2576 MOUSE; TRANSGENIC MOUSE;

AMYLOID PLAQUE; COGNITIVE AGEING; LIFE SPAN; NEURONAL LOSS; OXIDATIVE LOAD; TRANSLATIONAL MODEL VALIDITY;

AGE FACTORS; AGING; ALZHEIMER DISEASE; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LONGEVITY; MICE; MICE, TRANSGENIC; PHENOTYPE;

EID: 84896395043     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2013.12.009     Document Type: Review

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