-
2
-
-
0033536163
-
Immunization with amyloid-p attenuates Alzheimer-diseaselike pathology in the PDAPP mouse
-
Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, et al. Immunization with amyloid-p attenuates Alzheimer-diseaselike pathology in the PDAPP mouse. Nature 400: 173-177 (1999).
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
-
3
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F p-amyloid precursor protein
-
Games D, Adams D, Alessandrini R, Barbour R, Berthelette P, Blackwell R, et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F p-amyloid precursor protein. Nature 373: 523-527 (1995).
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, R.6
-
4
-
-
84984755327
-
Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey G, Hardy J, et al. Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 408: 982-985 (2000).
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, G.5
Hardy, J.6
-
5
-
-
0034700471
-
Aβ peptide immunization reduces behavioral impairment and plaques in a model of Alzheimer's disease
-
Janus C, Pearson J, McLaurin J, Mathews PM, Jiang Y, Schimdt SD, et al. Aβ peptide immunization reduces behavioral impairment and plaques in a model of Alzheimer's disease. Nature 408: 979-982 (2000).
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schimdt, S.D.6
-
6
-
-
0036852750
-
Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis
-
McLaurin J, Cecal R, Kierstead ME, Tian X, Phinney AL, Manea M, et al. Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis. Nat Med 8: 1263-1269 (2002).
-
(2002)
Nat Med
, vol.8
, pp. 1263-1269
-
-
McLaurin, J.1
Cecal, R.2
Kierstead, M.E.3
Tian, X.4
Phinney, A.L.5
Manea, M.6
-
7
-
-
11444267243
-
Evaluation of the safety and immunogenicity of synthetic Abeta42 (AN1792) in patients with AD
-
Bayer AJ, Bullock R, Jones RW, Wilkinson D, Paterson KR, Jenkins L, et al. Evaluation of the safety and immunogenicity of synthetic Abeta42 (AN1792) in patients with AD. Neurology 64: 94101 (2005).
-
(2005)
Neurology
, vol.64
, pp. 94101
-
-
Bayer, A.J.1
Bullock, R.2
Jones, R.W.3
Wilkinson, D.4
Paterson, K.R.5
Jenkins, L.6
-
8
-
-
10744230547
-
Subacute meningoencephalitis in a subset of patients with AD after Aβ42 immunization
-
Orgogozo J-M, Gilman S, Dartigues J-F, Laurent B, Puel M, Kirby LC, et al. Subacute meningoencephalitis in a subset of patients with AD after Aβ42 immunization. Neurology 61: 46-54 (2003).
-
(2003)
Neurology
, vol.61
, pp. 46-54
-
-
Orgogozo, J.-M.1
Gilman, S.2
Dartigues, J.-F.3
Laurent, B.4
Puel, M.5
Kirby, L.C.6
-
9
-
-
18144415471
-
Clinical effects of Aβ immunization (AN1792) in patients with AD in an interrupted trial
-
Gilman S, Killer M, Black RS, Jenkins L, Griffith SG, Fox NC, et al. Clinical effects of Aβ immunization (AN1792) in patients with AD in an interrupted trial. Neurology 64: 1563-1572 (2005).
-
(2005)
Neurology
, vol.64
, pp. 1563-1572
-
-
Gilman, S.1
Killer, M.2
Black, R.S.3
Jenkins, L.4
Griffith, S.G.5
Fox, N.C.6
-
10
-
-
20944448555
-
Effects of Aβ immunization (AN1792) on MRI measures of cerebral volume in Alzheimer's disease
-
Fox NC, Black RS, Gilman S, Rossor MN, Griffith SG, Jenkins L, et al. Effects of Aβ immunization (AN1792) on MRI measures of cerebral volume in Alzheimer's disease. Neurology 64: 1553-1562 (2005).
-
(2005)
Neurology
, vol.64
, pp. 1553-1562
-
-
Fox, N.C.1
Black, R.S.2
Gilman, S.3
Rossor, M.N.4
Griffith, S.G.5
Jenkins, L.6
-
11
-
-
1042265187
-
Neuropathology and pathogenesis of encephalitis following amyloid-p immunization in Alzheimer's disease
-
Ferrer I, Boada RM, Sanchez Guerra ML, Rossor MN, Griffith SG, Jenkins L, et al. Neuropathology and pathogenesis of encephalitis following amyloid-p immunization in Alzheimer's disease. Brain Pathol 14: 11-20 (2004).
-
(2004)
Brain Pathol
, vol.14
, pp. 11-20
-
-
Ferrer, I.1
Boada, R.M.2
Sanchez Guerra, M.L.3
Rossor, M.N.4
Griffith, S.G.5
Jenkins, L.6
-
12
-
-
19944429065
-
Aβ vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer's disease
-
Masliah E, Hansen L, Adame A, Crews L, Bard F, Lee C, et al. Aβ vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer's disease. Neurology 64: 129-131 (2005).
-
(2005)
Neurology
, vol.64
, pp. 129-131
-
-
Masliah, E.1
Hansen, L.2
Adame, A.3
Crews, L.4
Bard, F.5
Lee, C.6
-
13
-
-
0037393454
-
Neuropathology of human Alzheimer's disease after immunization with amyloid-β peptide: A case report
-
Nicoll JAR, Wilkinson D, Holmes C, Steart P, Markham H and Weller RO. Neuropathology of human Alzheimer's disease after immunization with amyloid-β peptide: a case report. Nat Med 9: 448-452 (2003).
-
(2003)
Nat Med
, vol.9
, pp. 448-452
-
-
Nicoll, J.A.R.1
Wilkinson, D.2
Holmes, C.3
Steart, P.4
Markham, H.5
Weller, R.O.6
-
14
-
-
0031452321
-
Functional disability in Alzheimer's disease
-
Gauthier S, Gelinas I and Gauthier L. Functional disability in Alzheimer's disease. Int Psychogeriatr 9(suppl 1): 163-165 (1997).
-
(1997)
Int Psychogeriatr
, vol.9
, Issue.SUPPL. 1
, pp. 163-165
-
-
Gauthier, S.1
Gelinas, I.2
Gauthier, L.3
-
15
-
-
0028100503
-
Assessing patient dependence in Alzheimer's disease
-
Stern Y, Albert SM, Sano M, Jacobs DM, Tang MX, Marder K, et al. Assessing patient dependence in Alzheimer's disease. J Gerontol 49: M216-222 (1994).
-
(1994)
J Gerontol
, vol.49
-
-
Stern, Y.1
Albert, S.M.2
Sano, M.3
Jacobs, D.M.4
Tang, M.X.5
Marder, K.6
-
16
-
-
0027425211
-
The Clinical Dementia Rating (CDR): Current version and scoring rules
-
Morris JC. The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 43: 2412-2414 (1993).
-
(1993)
Neurology
, vol.43
, pp. 2412-2414
-
-
Morris, J.C.1
-
17
-
-
34548639338
-
A neuropsychological test battery for use in Alzheimer's disease clinical trials
-
Harrison J, Minassian SL, Jenkins L, Black RS, Koller M and Grundman M. A neuropsychological test battery for use in Alzheimer's disease clinical trials. Arch Neurol 64: 1323-1329 (2007).
-
(2007)
Arch Neurol
, vol.64
, pp. 1323-1329
-
-
Harrison, J.1
Minassian, S.L.2
Jenkins, L.3
Black, R.S.4
Koller, M.5
Grundman, M.6
-
18
-
-
0016823810
-
Mini-mental state: A practical method for grading the cognitive state of patients for the clinician
-
Folstein MF, Folstein SE and McHugh PR. "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12: 189-198 (1975).
-
(1975)
J Psychiatr Res
, vol.12
, pp. 189-198
-
-
Folstein, M.F.1
Folstein, S.E.2
McHugh, P.R.3
-
19
-
-
0021520020
-
A new rating scale for Alzheimer's disease
-
Rosen WG, Mohs RC and Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry 141: 1356-1364 (1984).
-
(1984)
Am J Psychiatry
, vol.141
, pp. 1356-1364
-
-
Rosen, W.G.1
Mohs, R.C.2
Davis, K.L.3
|