A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model

Journal of Neuroscience

Volumn 25, Issue 12, 2005, Pages 3032-3040

  Lim, Giselle P ^a,c   Calon, Frédéric ^a,c,f   Morihara, Takashi ^a,c   Yang, Fusheng ^a,c   Teter, Bruce ^a,c   Ubeda, Oliver ^a,c   Salem Jr , Norman ^e   Frautschy, Sally A ^a,b,c,d   Cole, Greg M ^a,b,c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d Education and Clinical Center   (United States)

^e NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^f LAVAL UNIVERSITY   (Canada)

Author keywords

A ; Alzheimer; APP; DHA; Polyunsaturated fatty acid; Secretase

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; COMPLEMENTARY DNA; DOCOSAHEXAENOIC ACID; FATTY ACID; OMEGA 3 FATTY ACID; POLYUNSATURATED FATTY ACID; RNA;

AGING; ALZHEIMER DISEASE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEGENERATIVE DISEASE; DIET SUPPLEMENTATION; DIETARY INTAKE; FEMALE; GENE EXPRESSION; IMAGE ANALYSIS; IMMUNOBLOTTING; MALE; MOUSE; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SENILE PLAQUE;

ADMINISTRATION, ORAL; ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANALYSIS OF VARIANCE; ANIMALS; APOLIPOPROTEINS E; ASPARTIC ENDOPEPTIDASES; BLOTTING, WESTERN; CENTRAL NERVOUS SYSTEM; DIAGNOSTIC IMAGING; DIETARY FATS, UNSATURATED; DISEASE MODELS, ANIMAL; DOCOSAHEXAENOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FATTY ACIDS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; PREALBUMIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENILE PLAQUES; STATISTICS;

EID: 16244416174     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4225-04.2005     Document Type: Article

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