Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase

Biological Psychiatry

Volumn 68, Issue 10, 2010, Pages 922-929

  Yang, Hengxuan ^a   Zhuo, Jia Min ^a   Chu, Jin ^a   Chinnici, Cinzia ^a,b   Pratic, Domenico ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDITERRANEAN INSTITUTE FOR TRANSPLANTATION AND ADVANCED SPECIALIZED THERAPIES ISMETT   (Italy)

Author keywords

Alzheimer's disease; amyloid beta; lipoxygenase; transgenic animal models

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; BETA SECRETASE; BETA SECRETASE 1; BIOLOGICAL MARKER; BRAIN PROTEIN; CHOLESTEROL; GLIAL FIBRILLARY ACIDIC PROTEIN; POLYUNSATURATED FATTY ACID; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; RNA; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONDITIONING; CONTROLLED STUDY; ENZYME ACTIVITY; FEAR; FEMALE; GENE DELETION; HIPPOCAMPUS; HUMAN; INFLAMMATION; MALE; MEMORY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PROCESSING; SOMATOSENSORY CORTEX; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; BRAIN; CELL LINE, TRANSFORMED; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; FEMALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PLAQUE, AMYLOID; SIGNAL TRANSDUCTION;

EID: 78049423493     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2010.04.010     Document Type: Article

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