Age-dependent cerebrovascular abnormalities and blood flow disturbances in APP23 mice modeling Alzheimer's disease

Journal of Neuroscience

Volumn 23, Issue 24, 2003, Pages 8453-8459

  Beckmann, Nicolau ^a   Schuler, Alexandra ^b   Mueggler, Thomas ^a,d   Meyer, Eric P ^b   Wiederhold, Karl Heinz ^a   Staufenbiel, Matthias ^a   Krucker, Thomas ^c  

^a NOVARTIS PHARMA AG   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Alzheimer's disease; Amyloid precursor protein (APP); Angiography; Angiopathy; Cerebral amyloid angiopathy (CAA); Circle of Willis; Magnetic resonance angiography (MRA); Magnetic resonance imaging (MRI); Soluble amyloid; Transgenic mice

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

AGE; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL FUNCTION; BRAIN BLOOD VESSEL; BRAIN CIRCULUS ARTERIOSUS; CEREBROVASCULAR ACCIDENT; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; GENE MUTATION; GENE OVEREXPRESSION; HEMODYNAMICS; INTERNAL CAROTID ARTERY; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SENILE PLAQUE; TRANSGENIC MOUSE; VASCULAR AMYLOIDOSIS;

EID: 0141457931     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-24-08453.2003     Document Type: Article

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