Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

Nature Medicine

Volumn 13, Issue 4, 2007, Pages 432-438

  El Khoury, Joseph ^a   Toft, Michelle ^a   Hickman, Suzanne E ^a   Means, Terry K ^a   Terada, Kinya ^b   Geula, Changiz ^c,d   Luster, Andrew D ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CHEMOKINE RECEPTOR CCR2; NEUROTOXIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; BRAIN CELL; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; FLOW CYTOMETRY; GENE DOSAGE; IMMUNOCOMPETENT CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MICROGLIA; MONONUCLEAR PHAGOCYTE; MOUSE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; NUTRITIONAL DEFICIENCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENILE PLAQUE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANALYSIS OF VARIANCE; ANIMALS; BRAIN; CHEMOKINES; CROSSES, GENETIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; MICROGLIA; MODELS, IMMUNOLOGICAL; MONOCYTES; RECEPTORS, CCR2;

MUS; MUS MUSCULUS;

EID: 34147115541     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1555     Document Type: Article

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