High-level neuronal expression of Aβ(1-42) in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation

Journal of Neuroscience

Volumn 20, Issue 11, 2000, Pages 4050-4058

  Mucke, Lennart ^a,b,e   Masliah, Eliezer ^c   Yu, Gui Qiu ^a   Mallory, Margaret ^c   Rockenstein, Edward M ^c   Tatsuno, Gwen ^d   Hu, Kang ^d   Kholodenko, Dora ^d   Johnson Wood, Kelly ^d   McConlogue, Lisa ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d ELAN PHARMACEUTICALS   (United States)

^e GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

Author keywords

Alzheimer's disease; Amyloid; APP; Neurodegeneration; Synapses; Transgenic mice

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AMYLOID PROTEIN;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; BRAIN REGION; COGNITIVE DEFECT; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; GENE MUTATION; MOUSE; NERVE DEGENERATION; NERVE ENDING; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SENILE PLAQUE; TRANSGENIC MOUSE;

EID: 0034213718     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-11-04050.2000     Document Type: Article

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