Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits

Neurochemistry International

Volumn 57, Issue 4, 2010, Pages 375-382

  Jardanhazi Kurutz, Daniel ^a,b   Kummer, Markus P ^b   Terwel, Dick ^b   Vogel, Kim ^a   Dyrks, Thomas ^a   Thiele, Andrea ^a   Heneka, Michael T ^b  

^a BAYER PHARMA AG   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Alzheimer's disease; Dsp4; Locus ceruleus; Neuroinflammation; Norepinephrine transporter; Spatial memory

Indexed keywords

2 BROMO N (2 CHLOROETHYL) N ETHYLBENZYLAMINE; AMYLOID PRECURSOR PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NORADRENALIN; NORADRENALIN TRANSPORTER; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEGENERATION; COGNITIVE DEFECT; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LOCUS CERULEUS; MAZE TEST; MOUSE; NEUROPATHOLOGY; NONHUMAN; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL; SPATIAL MEMORY; TRANSGENIC MOUSE;

AGING; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOIDOSIS; ANIMALS; BEHAVIOR, ANIMAL; BENZYLAMINES; COGNITION DISORDERS; EXPLORATORY BEHAVIOR; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LOCUS COERULEUS; MAZE LEARNING; MEMORY; MICE; MICE, TRANSGENIC; NERVE DEGENERATION; NEUROTRANSMITTER UPTAKE INHIBITORS; NOREPINEPHRINE; PRESENILIN-1; RECOGNITION (PSYCHOLOGY); RNA, MESSENGER;

MUS; MUS MUSCULUS;

EID: 77956225289     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2010.02.001     Document Type: Article

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