Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-β accumulation and independently accelerates the development of tau abnormalities

Journal of Neuroscience

Volumn 31, Issue 26, 2011, Pages 9513-9525

  Tran, Hien T ^a   LaFerla, Frank M ^c   Holtzman, David M ^a,b   Brody, David L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; IMMUNOREACTIVITY; MALE; MOUSE; NERVE DEGENERATION; NERVE FIBER; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RISK ASSESSMENT; TRANSGENIC MOUSE; TRAUMATIC BRAIN INJURY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANALYSIS OF VARIANCE; ANIMALS; AXONS; BLOTTING, WESTERN; BRAIN; BRAIN INJURIES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; NEUROFIBRILLARY TANGLES; TAU PROTEINS; TAUOPATHIES;

EID: 79959941349     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0858-11.2011     Document Type: Article

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