Longitudinal characterization of the brain proteomes for the Tg2576 amyloid mouse model using shotgun based mass spectrometry

Journal of Proteome Research

Volumn 11, Issue 12, 2012, Pages 6159-6174

  Shevchenko, Ganna ^a   Wetterhall, Magnus ^a   Bergquist, Jonas ^a   Höglund, Kina ^b   Andersson, Lars I ^c   Kultima, Kim ^d  

^a UPPSALA UNIVERSITY   (Sweden)

^b SCIENCE FOR LIFE LABORATORY   (Sweden)

^c ASTRAZENECA R AND D   (Sweden)

^d UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

cloud point extraction (CPE); label free quantification; mass spectrometry; neurodegeneration; proteomics; Tg2576 mouse model

Indexed keywords

AMYLOID PROTEIN; MITOCHONDRIAL PROTEIN; PROTEOME;

AMYLOID PLAQUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN MAPPING; CONTROLLED STUDY; DISEASE COURSE; FEMALE; LONGITUDINAL STUDY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; QUANTITATIVE ANALYSIS; UPREGULATION;

AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; BRAIN; CLUSTER ANALYSIS; DISEASE PROGRESSION; HUMANS; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MULTIVARIATE ANALYSIS; PLAQUE, AMYLOID; PRINCIPAL COMPONENT ANALYSIS; PROTEIN INTERACTION MAPPING; PROTEIN INTERACTION MAPS; PROTEOME; TANDEM MASS SPECTROMETRY; TIME FACTORS;

MUS MUSCULUS;

EID: 84870935048     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr300808h     Document Type: Article

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