-
1
-
-
34648859471
-
Oxidative damage in mild cognitive impairment and early Alzheimer's disease
-
DOI 10.1002/jnr.21346
-
Lovell MA, Markesbery WR. Oxidative damage in mild cognitive impairment and early Alzheimer's disease. J Neurosci Res. 2007;85(14):3036-3040. (Pubitemid 350057358)
-
(2007)
Journal of Neuroscience Research
, vol.85
, Issue.14
, pp. 3036-3040
-
-
Lovell, M.A.1
Markesbery, W.R.2
-
2
-
-
0036710931
-
Lipid peroxidation in aging brain and Alzheimer's disease
-
DOI 10.1016/S0891-5849(02)00807-9, PII S0891584902008079
-
Montine TJ, Neely MD, Quinn JF, et al. Lipid peroxidation in aging brain and Alzheimer's disease. Free Radic Biol Med. 2002;33(5):620-626. (Pubitemid 35245834)
-
(2002)
Free Radical Biology and Medicine
, vol.33
, Issue.5
, pp. 620-626
-
-
Montine, T.J.1
Neely, M.D.2
Quinn, J.F.3
Beal, M.F.4
Markesbery, W.R.5
Roberts II, L.J.6
Morrow, J.D.7
-
3
-
-
69149089066
-
The role of nutrition in Alzheimer's disease: Epidemiological evidence
-
Morris MC. The role of nutrition in Alzheimer's disease: epidemiological evidence. Eur J Neurol. 2009;16(suppl 1):1-7.
-
(2009)
Eur J Neurol
, vol.16
, Issue.SUPPL. 1
, pp. 1-7
-
-
Morris, M.C.1
-
4
-
-
8644272506
-
Impact of antioxidants, zinc, and copper on cognition in the elderly: A randomized, controlled trial
-
Yaffe K, Clemons TE, McBee WL, Lindblad AS; Age-Related Eye Disease Study Research Group. Impact of antioxidants, zinc, and copper on cognition in the elderly: a randomized, controlled trial. Neurology. 2004;63(9):1705-1707. (Pubitemid 39507595)
-
(2004)
Neurology
, vol.63
, Issue.9
, pp. 1705-1707
-
-
Yaffe, K.1
Clemons, T.E.2
McBee, W.L.3
Lindblad, A.S.4
-
5
-
-
0037031094
-
MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: A randomised placebo-controlled trial
-
Heart Protection Study Collaborative Group
-
Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet. 2002;360(9326):23-33.
-
(2002)
Lancet
, vol.360
, Issue.9326
, pp. 23-33
-
-
-
6
-
-
0030967165
-
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease
-
DOI 10.1056/NEJM199704243361704
-
Sano M, Ernesto C, Thomas RG, et al. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease: the Alzheimer's Disease Cooperative Study. N Engl J Med. 1997;336(17):1216-1222. (Pubitemid 27183651)
-
(1997)
New England Journal of Medicine
, vol.336
, Issue.17
, pp. 1216-1222
-
-
Sano, M.1
Ernesto, C.2
Thomas, R.G.3
Klauber, M.R.4
Schafer, K.5
Grundman, M.6
Woodbury, P.7
Growdon, J.8
Cotman, C.W.9
Pfeiffer, E.10
Schneider, L.S.11
Thal, L.J.12
-
7
-
-
20344381835
-
Vitamin E and donepezil for the treatment of mild cognitive impairment
-
DOI 10.1056/NEJMoa050151
-
Petersen RC, Thomas RG, Grundman M, et al Alzheimer's Disease Cooperative Study Group. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med. 2005;352(23):2379-2388. (Pubitemid 40958434)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.23
, pp. 2379-2388
-
-
Petersen, R.C.1
Thomas, R.G.2
Grundman, M.3
Bennett, D.4
Doody, R.5
Ferris, S.6
Galasko, D.7
Jin, S.8
Kaye, J.9
Levey, A.10
Pfeiffer, E.11
Sano, M.12
Van Dyck, C.H.13
Thal, L.J.14
-
8
-
-
0036751954
-
Oxidative stress in brain aging: Implications for therapeutics of neurodegenerative diseases
-
DOI 10.1016/S0197-4580(02)00019-2, PII S0197458002000192
-
Floyd RA, Hensley K. Oxidative stress in brain aging: implications for therapeutics of neurodegenerative diseases. Neurobiol Aging. 2002;23(5):795-807. (Pubitemid 35217704)
-
(2002)
Neurobiology of Aging
, vol.23
, Issue.5
, pp. 795-807
-
-
Floyd, R.A.1
Hensley, K.2
-
9
-
-
2342544918
-
Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress
-
Smith AR, Shenvi SV, Widlansky M, Suh JH, Hagen TM. Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. Curr Med Chem. 2004;11(9):1135-1146. (Pubitemid 38585058)
-
(2004)
Current Medicinal Chemistry
, vol.11
, Issue.9
, pp. 1135-1146
-
-
Smith, A.R.1
Shenvi, S.V.2
Widlansky, M.3
Suh, J.H.4
Hagen, T.M.5
-
10
-
-
1442314722
-
Early vitamin e supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease
-
Sung S, Yao Y, Uryu K, et al. Early vitamin E supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease. FASEB J. 2004;18(2):323-325.
-
(2004)
FASEB J
, vol.18
, Issue.2
, pp. 323-325
-
-
Sung, S.1
Yao, Y.2
Uryu, K.3
-
11
-
-
71049178586
-
Antioxidants and cognitive training interact to affect oxidative stress and memory in APP/PSEN1 mice
-
Harrison FE, Allard J, Bixler R, et al. Antioxidants and cognitive training interact to affect oxidative stress and memory in APP/PSEN1 mice. Nutr Neurosci. 2009;12(5):203-218.
-
(2009)
Nutr Neurosci
, vol.12
, Issue.5
, pp. 203-218
-
-
Harrison, F.E.1
Allard, J.2
Bixler, R.3
-
12
-
-
33750580699
-
Plaque-derived oxidative stress mediates distorted neurite trajectories in the Alzheimer mouse model
-
DOI 10.1097/01.jnen.0000240468.12543.af, PII 0000507220061100000007
-
Garcia-Alloza M, Dodwell SA, Meyer-Luehmann M, Hyman BT, Bacskai BJ. Plaque-derived oxidative stress mediates distorted neurite trajectories in the Alzheimer mouse model. J Neuropathol Exp Neurol. 2006;65(11):1082-1089. (Pubitemid 44684666)
-
(2006)
Journal of Neuropathology and Experimental Neurology
, vol.65
, Issue.11
, pp. 1082-1089
-
-
Garcia-Alloza, M.1
Dodwell, S.A.2
Meyer-Luehmann, M.3
Hyman, B.T.4
Bacskai, B.J.5
-
13
-
-
58149380028
-
The canine (dog) model of human aging and disease: Dietary, environmental and immunotherapy approaches
-
Cotman CW, Head E. The canine (dog) model of human aging and disease: dietary, environmental and immunotherapy approaches. J Alzheimers Dis. 2008;15(4):685-707.
-
(2008)
J Alzheimers Dis
, vol.15
, Issue.4
, pp. 685-707
-
-
Cotman, C.W.1
Head, E.2
-
14
-
-
33845442944
-
Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice
-
DOI 10.1016/j.neurobiolaging.2005.12.014, PII S0197458005004537
-
Quinn JF, Bussiere JR, Hammond RS, et al. Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice. Neurobiol Aging. 2007;28(2):213-225. (Pubitemid 44894634)
-
(2007)
Neurobiology of Aging
, vol.28
, Issue.2
, pp. 213-225
-
-
Quinn, J.F.1
Bussiere, J.R.2
Hammond, R.S.3
Montine, T.J.4
Henson, E.5
Jones, R.E.6
Stackman Jr., R.W.7
-
15
-
-
60349086658
-
Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease
-
Siedlak SL, Casadesus G, Webber KM, et al. Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease. Free Radic Res. 2009;43(2):156-164.
-
(2009)
Free Radic Res
, vol.43
, Issue.2
, pp. 156-164
-
-
Siedlak, S.L.1
Casadesus, G.2
Webber, K.M.3
-
16
-
-
38449099641
-
Alpha-lipoic acid as a new treatment option for Alzheimer's disease: A 48months follow-up analysis
-
Hager K, Kenklies M, McAfoose J, Engel J, Münch G. Alpha-lipoic acid as a new treatment option for Alzheimer's disease: a 48months follow-up analysis. J Neural Transm Suppl. 2007;72(72):189-193.
-
(2007)
J Neural Transm Suppl
, vol.72
, Issue.72
, pp. 189-193
-
-
Hager, K.1
Kenklies, M.2
McAfoose, J.3
Engel, J.4
Münch, G.5
-
17
-
-
10244246626
-
10 as a potential treatment
-
DOI 10.1023/B:JOBB.0000041772.74810.92
-
Beal MF.Mitochondrial dysfunction and oxidative damage in Alzheimer's and Parkinson's diseases and coenzyme Q10 as a potential treatment. J Bioenerg Biomembr. 2004;36(4):381-386. (Pubitemid 39619845)
-
(2004)
Journal of Bioenergetics and Biomembranes
, vol.36
, Issue.4 SPEC.ISS.
, pp. 381-386
-
-
Beal, M.F.1
-
18
-
-
42949122109
-
Coenzyme Q10 attenuates beta-amyloid pathology in the aged transgenic mice with Alzheimer presenilin 1mutation
-
Yang X, Yang Y, Li G, Wang J, Yang ES. Coenzyme Q10 attenuates beta-amyloid pathology in the aged transgenic mice with Alzheimer presenilin 1mutation. J Mol Neurosci. 2008;34(2):165-171.
-
(2008)
J Mol Neurosci
, vol.34
, Issue.2
, pp. 165-171
-
-
Yang, X.1
Yang, Y.2
Li, G.3
Wang, J.4
Yang, E.S.5
-
19
-
-
47849101646
-
Evaluation of coenzyme Q as an antioxidant strategy for Alzheimer's disease
-
Wadsworth TL, Bishop JA, Pappu AS, Woltjer RL, Quinn JF. Evaluation of coenzyme Q as an antioxidant strategy for Alzheimer's disease. J Alzheimers Dis. 2008;14(2):225-234. (Pubitemid 352040040)
-
(2008)
Journal of Alzheimer's Disease
, vol.14
, Issue.2
, pp. 225-234
-
-
Wadsworth, T.L.1
Bishop, J.A.2
Pappu, A.S.3
Woltjer, R.L.4
Quinn, J.F.5
-
20
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
-
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34(7):939-944. (Pubitemid 14076461)
-
(1984)
Neurology
, vol.34
, Issue.7
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
-
21
-
-
0016823810
-
"Mini-mental state": A practical method for grading the cognitive state of patients for the clinician
-
Folstein MF, Folstein SE, McHugh PR. "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-198.
-
(1975)
J Psychiatr Res
, vol.12
, Issue.3
, pp. 189-198
-
-
Folstein, M.F.1
Folstein, S.E.2
McHugh, P.R.3
-
22
-
-
3042814742
-
Galantamine maintains ability to perform activities of daily living in patients with Alzheimer's disease
-
DOI 10.1111/j.1532-5415.2004.52303.x
-
Galasko D, Kershaw PR, Schneider L, Zhu Y, Tariot PN. Galantamine maintains ability to perform activities of daily living in patients with Alzheimer's disease. J Am Geriatr Soc. 2004;52(7):1070-1076. (Pubitemid 38869064)
-
(2004)
Journal of the American Geriatrics Society
, vol.52
, Issue.7
, pp. 1070-1076
-
-
Galasko, D.1
Kershaw, P.R.2
Schneider, L.3
Zhu, Y.4
Tariot, P.N.5
-
23
-
-
33744946694
-
The role of biomarkers in clinical trials for Alzheimer disease
-
DOI 10.1097/01.wad.0000191420.61260.a8, PII 0000209320060100000003
-
Thal LJ, Kantarci K, Reiman EM, et al. The role of biomarkers in clinical trials for Alzheimer disease. Alzheimer Dis Assoc Disord. 2006;20(1):6-15. (Pubitemid 44356888)
-
(2006)
Alzheimer Disease and Associated Disorders
, vol.20
, Issue.1
, pp. 6-15
-
-
Thal, L.J.1
Kantarci, K.2
Reiman, E.M.3
Klunk, W.E.4
Weiner, M.W.5
Zetterberg, H.6
Galasko, D.7
Pratico, D.8
Griffin, S.9
Schenk, D.10
Siemers, E.11
-
24
-
-
77949423619
-
Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
-
Blennow K, Hampel H, Weiner M, Zetterberg H. Cerebrospinal fluid and plasma biomarkers in Alzheimer disease. Nat Rev Neurol. 2010;6(3):131-144.
-
(2010)
Nat Rev Neurol
, vol.6
, Issue.3
, pp. 131-144
-
-
Blennow, K.1
Hampel, H.2
Weiner, M.3
Zetterberg, H.4
-
25
-
-
77951689435
-
Biomarkers of oxidative damage and inflammation in Alzheimer's disease
-
Galasko D, Montine TJ. Biomarkers of oxidative damage and inflammation in Alzheimer's disease. Biomark Med. 2010;4(1):27-36.
-
(2010)
Biomark Med
, vol.4
, Issue.1
, pp. 27-36
-
-
Galasko, D.1
Montine, T.J.2
-
26
-
-
0032588611
-
2-isoprostane concentration in probable AD
-
Montine TJ, Beal MF, Cudkowicz ME, et al. Increased CSF F2-isoprostane concentration in probable AD. Neurology. 1999;52(3):562-565. (Pubitemid 29075604)
-
(1999)
Neurology
, vol.52
, Issue.3
, pp. 562-565
-
-
Montine, T.J.1
Beal, M.F.2
Cudkowicz, M.E.3
O'Donnell, H.4
Margolin, R.A.5
McFarland, L.6
Bachrach, A.F.7
Zackert, W.E.8
Roberts, L.J.9
Morrow, J.D.10
-
27
-
-
47549117283
-
Biochemical markers in persons with preclinical familial Alzheimer disease
-
Ringman JM, Younkin SG, Pratico D, et al. Biochemical markers in persons with preclinical familial Alzheimer disease. Neurology. 2008;71(2):85-92.
-
(2008)
Neurology
, vol.71
, Issue.2
, pp. 85-92
-
-
Ringman, J.M.1
Younkin, S.G.2
Pratico, D.3
-
28
-
-
12944312683
-
181) in cerebrospinal fluid by the xMAP technology
-
DOI 10.1373/clinchem.2004.039347
-
Olsson A, Vanderstichele H, Andreasen N, et al. Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology. Clin Chem. 2005;51(2):336-345. (Pubitemid 40175803)
-
(2005)
Clinical Chemistry
, vol.51
, Issue.2
, pp. 336-345
-
-
Olsson, A.1
Vanderstichele, H.2
Andreasen, N.3
De Meyer, G.4
Wallin, A.5
Holmberg, B.6
Rosengren, L.7
Vanmechelen, E.8
Blennow, K.9
-
29
-
-
33645762226
-
A sharper Bonferroni procedure for multiple tests of significance
-
doi:10.2307/2336325
-
Hochberg Y. A sharper Bonferroni procedure for multiple tests of significance. Biometrika. 1988;75(4):800-802. doi:10.2307/2336325.
-
(1988)
Biometrika
, vol.75
, Issue.4
, pp. 800-802
-
-
Hochberg, Y.1
-
30
-
-
34247893817
-
Longitudinal stability of CSF biomarkers in Alzheimer's disease
-
DOI 10.1016/j.neulet.2007.03.064, PII S0304394007003424
-
Blennow K, Zetterberg H, Minthon L, et al. Longitudinal stability of CSF biomarkers in Alzheimer's disease. Neurosci Lett. 2007;419(1):18-22. (Pubitemid 46694097)
-
(2007)
Neuroscience Letters
, vol.419
, Issue.1
, pp. 18-22
-
-
Blennow, K.1
Zetterberg, H.2
Minthon, L.3
Lannfelt, L.4
Strid, S.5
Annas, P.6
Basun, H.7
Andreasen, N.8
-
31
-
-
0032555066
-
Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects
-
Matthews RT, Yang L, Browne S, Baik M, Beal MF. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci U S A. 1998;95(15):8892-8897.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.15
, pp. 8892-8897
-
-
Matthews, R.T.1
Yang, L.2
Browne, S.3
Baik, M.4
Beal, M.F.5
-
32
-
-
0036771852
-
Effects of coenzyme Q10 in early Parkinson disease: Evidence of slowing of the functional decline
-
Parkinson Study Group
-
Shults CW, Oakes D, Kieburtz K, et al Parkinson Study Group. Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline. Arch Neurol. 2002;59(10):1541-1550.
-
(2002)
Arch Neurol
, vol.59
, Issue.10
, pp. 1541-1550
-
-
Shults, C.W.1
Oakes, D.2
Kieburtz, K.3
-
33
-
-
70249116820
-
Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III
-
QALS Study Group
-
Kaufmann P, Thompson JL, Levy G, et al QALS Study Group. Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III. Ann Neurol. 2009; 66(2):235-244.
-
(2009)
Ann Neurol
, vol.66
, Issue.2
, pp. 235-244
-
-
Kaufmann, P.1
Thompson, J.L.2
Levy, G.3
-
34
-
-
0344738681
-
Idebenone treatment fails to slow cognitive decline in Alzheimer's disease
-
Thal LJ, Grundman M, Berg J, et al. Idebenone treatment fails to slow cognitive decline in Alzheimer's disease. Neurology. 2003;61(11):1498-1502. (Pubitemid 37505568)
-
(2003)
Neurology
, vol.61
, Issue.11
, pp. 1498-1502
-
-
Thal, L.J.1
Grundman, M.2
Berg, J.3
Ernstrom, K.4
Margolin, R.5
Pfeiffer, E.6
Weiner, M.F.7
Zamrini, E.8
Thomas, R.G.9
-
35
-
-
70350435850
-
Antioxidants and aging: NMR-based evidence of improved skeletal muscle perfusion and energetics
-
Wray DW, Nishiyama SK, Monnet A, et al. Antioxidants and aging: NMR-based evidence of improved skeletal muscle perfusion and energetics. Am J Physiol Heart Circ Physiol. 2009;297(5):H1870-H1875.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
, Issue.5
-
-
Wray, D.W.1
Nishiyama, S.K.2
Monnet, A.3
-
36
-
-
19944427642
-
Meta-analysis: High-dosage vitamin e supplementation may increase all-cause mortality
-
Miller ER III, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med. 2005;142(1):37-46.
-
(2005)
Ann Intern Med
, vol.142
, Issue.1
, pp. 37-46
-
-
Miller III, E.R.1
Pastor-Barriuso, R.2
Dalal, D.3
Riemersma, R.A.4
Appel, L.J.5
Guallar, E.6
-
37
-
-
33745920161
-
Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo
-
DOI 10.1038/nm1438, PII NM1438
-
Bateman RJ, Munsell LY, Morris JC, Swarm R, Yarasheski KE, Holtzman DM. Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Nat Med. 2006;12(7):856-861. (Pubitemid 44050079)
-
(2006)
Nature Medicine
, vol.12
, Issue.7
, pp. 856-861
-
-
Bateman, R.J.1
Munsell, L.Y.2
Morris, J.C.3
Swarm, R.4
Yarasheski, K.E.5
Holtzman, D.M.6
-
38
-
-
0035910638
-
Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke
-
DOI 10.1016/S0304-3940(00)01697-9, PII S0304394000016979
-
Hesse C, Rosengren L, Andreasen N, et al. Transient increase in total tau but not phosphotau in human cerebrospinal fluid after acute stroke. Neurosci Lett. 2001;297(3):187-190. (Pubitemid 32011305)
-
(2001)
Neuroscience Letters
, vol.297
, Issue.3
, pp. 187-190
-
-
Hesse, C.1
Rosengren, L.2
Andreasen, N.3
Davidsson, P.4
Vanderstichele, H.5
Vanmechelen, E.6
Blennow, K.7
|