Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency

Stroke

Volumn 30, Issue 9, 1999, Pages 1962-1968

  Kawase, Makoto ^a,d   Murakami, Kensuke ^a   Fujimura, Miki ^b   Morita Fujimura, Yuiko ^c   Gasche, Yvan ^a   Kondo, Takeo ^b   Scott, Richard W ^c   Chan, Pak H ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CEPHALON INC   (United States)

^d STANFORD UNIVERSITY   (United States)

Author keywords

Cerebral ischemia, global; Free radicals; Hippocampus; Mice; Oxidative stress; Superoxide dismutase; Superoxides

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; ETHIDIUM; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; CELL DAMAGE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; FLUORESCENCE; HIPPOCAMPUS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032883894     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.30.9.1962     Document Type: Article

References (35)

1. Kontos HA. George E. Brown memorial lecture: oxygen radicals in cerebral vascular injury. Circ Res. 1985;57:508-516.
2. Coyle JT, Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science. 1993;262:689-695.
3. Chan PH. Oxygen radicals in focal cerebral ischemia. Brain Pathol. 1994;4:59-65.
4. Chan PH. Role of oxidants in ischémie brain damage. Stroke. 1996;27: 1124-1129.
5. Fridovich I. Biological effects of the Superoxide radical. Arch Biochem Biophys. 1986;247:1-11.
6. Patel M, Day BJ, Crapo JD, Fridovich I, McNamara JO. Requirement for Superoxide in excitotoxic cell death. Neuron. 1996:16:345-355.
7. Chan PH, Yang GY, Chen SF, Carlson E, Epstein CJ. Cold-induced brain edema and infarction are reduced in transgenic mice overexpressing CuZn-superoxide dismutase. Ann Neural 1991;29:482-486.
8. Kinouchi H, Epstein CJ, Mizui T, Carlson E, Chen SF, Chan PH. Attenuation of focal cerebral ischémie injury in transgenic mice overexpressing CuZn Superoxide dismutase. Proc Natl Acad Sei USA. 1991;88: 11158-11162.
9. Mikawa S, Kinouchi H, Kamii H, Gobbel GT, Chen SF, Carlson E, Epstein CJ, Chan PH. Attenuation of acute and chronic damage following traumatic brain injury in copper, zinc-superoxide dismutase transgenic mice. J Neurosurg. 1996;85:885-891.
10. Yang G, Chan PH, Chen J, Carlson E, Chen SF, Weinstein P, Epstein CJ, Kamii H. Human copper-zinc Superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. Stroke. 1994:25:165-170.
11. Ito U, Spatz M, Walker JJ, Klatzo I. Experimental cerebral ischemia in. Mongolian gerbils, I: light microscopic observations. Acta Neuropathol (Berl). 1975:32:209-223.
12. Pulsinelli WA, Brierley JB, Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neural. 1982:11:491-498.
13. Kirino T. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 1982;239:57-69.
14. MacManus JP, Buchan AM, Hill IE, Rasquinha I, Preston E. Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain. Neurosci Lett. 1993:164:89-92.
15. Nitatori T, Sato N, Waguri S, Karasawa Y, Araki H, Shibanai K, Kominami E, Uchiyama Y. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J Neurosci. 1995:15:1001-1011.
16. Greenlund L. Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron. 1995; 14:303-315.
17. Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell. 1993;75:241-245.
18. Kane DJ, Sarafian TA, Anton R, Hahn H, Gralla EB, Valentine JS, Ord T, Bredesen DE. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science. 1993:262:1274-1277.
19. Kawase M, Fujimura M, Morita-Fujimura Y, Chan PH. Reduction of apurinic/apyrimidinic endonuclease expression after transient global cerebral ischemia in rats: implication of the failure of DNA repair in neuronal apoptosis. Stroke. 1999:30:441-449.
20. Chan PH, Kawase M, Murakami K, Chen SF, Li Y, Calagui B, Reola L, Carlson E, Epstein CJ. Overexpression of SOD 1 rats protects vulnerable neurons against ischémie damage after global cerebral ischemia and reperfusion. J Neurosci. 1998;18:8292-8299.
21. Murakami K, Kondo T, Epstein CJ, Chan PH. Overexpression of CuZnsuperoxide dismutase reduces hippocampal injury after global ischemia in transgenic mice. Stroke. 1997;28:1797-1804.
22. Reaume AG, Elliott JL, Huffman EK, Kowall NW, Ferrante RJ, Siwek DF, Wilcox HM, Flood DG, Béai MF, Brown RJ, Scott RW, Snider \VD. Motor neurons in Cu/Zn Superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat Genet. 1996;13:43-47.
23. Epstein CJ, Avraham KB, Lovett M, Smith S, Elroy SO, Rotman G, Bry C, Groner Y. Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome. Proc NatlAcadSci USA. 1987;84:8044-8048.
24. Bindokas VP, Jordan J, Lee CC, Miller RJ. Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J Neurosd. 1996;16:1324-1336.
25. Murakami K, Kondo T, Kawase M, Li Y, Sato S, Chen SF, Chan PH. Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese Superoxide dismutase deficiency. J Neurosd. 1998;18: 205-213.
26. Fujimura M, Morita-Fujimura Y, Kawase M, Copin J-C, Calagui B, Epstein CJ, Chan PH. Manganese Superoxide dismutase mediates the early release of mitochondria! cytochrome c and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. J Neurosd. 1999;19:3414-3422.
27. Kondo T, Reaume AC, Huang TT, Carlson E, Murakami K, Chen SF, Hoffman EK, Scott RW, Epstein CJ, Chan PH. Reduction of CuZnsuperoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. J Neurosd. 1997;17: 4180-4189.
28. Murakami K, Kondo T, Kawase M, Chan PH. The development of a new mouse model of global ischemia: focus on the relationships between ischemia duration, anesthesia, cerebral vasculature, and neuronal injury following global ischemia in mice. Brain Res. 1998;780:304-310.
29. Kondo T, Li Y, Sato S, Murakami K, Copin J, Huang T, Epstein C, Chan P. Subcellular localization of Superoxide anions following focal cerebral ischemia and reperfusion. J Cereb Blood Flow Melab. 1997;17(suppl 1):S102. Abstract.
30. Greenlund LJ, Deckwerth TL, Johnson EM Jr. Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron. 1995;14:303-315.
31. Sei Y, Von Lubitz KJ, Basile AS, Borner MM, Lin RC, Skolnick P, Fossom LH. Intemucleosomal DNA fragmentation in gerbil hippocampus following forebrain ischemia. Neurosci Lett. 1994;171:179-182.
32. Petito CK, Torres-Munoz J, Roberts B, Olarte J-P, Nowak TS Jr, Pulsinelli \VA. DNA fragmentation follows delayed neuronal death in CA1 neurons exposed to transient global ischemia in the rat. J Cereb Blood Flow Utetab. 1997;17:967-976.
33. Heron A, Pollard H, Dessi F, Moreau J, Lasbennes F, Ben-Ari Y. Regional variability in DNA fragmentation after global ischemia evidenced by combined histological and gel electrophoresis observation in the rat brain. J Neuwchem. 1993;61:1973-1976.
34. Chen J, Nagayama T, Jin K, Stetler RA, Zhu RL, Graham SH, Simon RP. Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. J Neurosci. 1998; 18:4914-4928.
35. Mitra S, Hazra TK, Roy R, Ikeda S, Biswas T, Lock J, Boldogh I, Izumi T. Complexities of DNA base excision repair in mammalian cells. Mol Cells. 1997;7:305-312.