-
1
-
-
84895895175
-
Skelett, Muskulatur und Bindegewebe
-
5th edn. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart
-
Thews G, Mutschler E, Vaupel P. (1999) Skelett, Muskulatur und Bindegewebe. In: Anatomie, Physiologie, Pathophysiologie des Menschen, 5th edn. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, pp. 553-603
-
(1999)
Anatomie, Physiologie, Pathophysiologie des Menschen
, pp. 553-603
-
-
Thews, G.1
Mutschler, E.2
Vaupel, P.3
-
2
-
-
84895893885
-
Cellular energetics
-
6th edn. W.H. Freeman and Company, New York
-
Lodish H, Berk A, Kaiser CA, Krieger M, Scott MP, Bretscher A, Ploegh H, Matsudaira P (2007) Cellular energetics. In: Molecular cell biology, 6th edn. W.H. Freeman and Company, New York, pp 479-532
-
(2007)
Molecular Cell Biology
, pp. 479-532
-
-
Lodish, H.1
Berk, A.2
Kaiser, C.A.3
Krieger, M.4
Scott, M.P.5
Bretscher, A.6
Ploegh, H.7
Matsudaira, P.8
-
3
-
-
84857861919
-
Mechanisms for insulin resistance: Common threads and missing links
-
Samuel VT, Shulman GI (2012) Mechanisms for insulin resistance: common threads and missing links. Cell 148:852-871
-
(2012)
Cell
, vol.148
, pp. 852-871
-
-
Samuel, V.T.1
Shulman, G.I.2
-
4
-
-
0036796875
-
Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
-
DOI 10.1210/er.2001-0039
-
Evans JL, Goldfine ID, Maddux BA, Grodsky GM (2002) Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 23:599-622 (Pubitemid 35191625)
-
(2002)
Endocrine Reviews
, vol.23
, Issue.5
, pp. 599-622
-
-
Evans, J.L.1
Goldfine, I.D.2
Maddux, B.A.3
Grodsky, G.M.4
-
5
-
-
26444442450
-
Endoplasmic reticulum stress: Cell life and death decisions
-
DOI 10.1172/JCI26373
-
Xu C, Bailly-Maitre B, Reed JC (2005) Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 115:2656-2664 (Pubitemid 41434389)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.10
, pp. 2656-2664
-
-
Xu, C.1
Bailly-Maitre, B.2
Reed, J.C.3
-
6
-
-
84856737149
-
Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells
-
Hage Hassan R, Hainault I, Vilquin JT, Samama C, Lasnier F, Ferre P, Foufelle F, Hajduch E (2012) Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells. Diabetologia 55:204-214
-
(2012)
Diabetologia
, vol.55
, pp. 204-214
-
-
Hage Hassan, R.1
Hainault, I.2
Vilquin, J.T.3
Samama, C.4
Lasnier, F.5
Ferre, P.6
Foufelle, F.7
Hajduch, E.8
-
7
-
-
84855791512
-
Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance
-
Rieusset J, Chauvin MA, Durand A, Bravard A, Laugerette F, Michalski MC, Vidal H (2012) Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance. Biochem Biophys Res Commun 417:439-445
-
(2012)
Biochem Biophys Res Commun
, vol.417
, pp. 439-445
-
-
Rieusset, J.1
Chauvin, M.A.2
Durand, A.3
Bravard, A.4
Laugerette, F.5
Michalski, M.C.6
Vidal, H.7
-
8
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
DOI 10.1016/S0092-8674(00)81410-5
-
Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM(1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92:829-839 (Pubitemid 28155321)
-
(1998)
Cell
, vol.92
, Issue.6
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
9
-
-
0033977890
-
The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes
-
DOI 10.1128/MCB.20.5.1868-1876.2000
-
Vega RB, Huss JM, Kelly DP (2000) The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes. Mol Cell Biol 20:1868-1876 (Pubitemid 30100203)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.5
, pp. 1868-1876
-
-
Vega, R.B.1
Huss, J.M.2
Kelly, D.P.3
-
10
-
-
0037453718
-
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity
-
DOI 10.1016/S0092-8674(03)00269-1
-
Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM (2003) Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell 113:159-170 (Pubitemid 36514968)
-
(2003)
Cell
, vol.113
, Issue.2
, pp. 159-170
-
-
Wang, Y.-X.1
Lee, C.-H.2
Tiep, S.3
Yu, R.T.4
Ham, J.5
Kang, H.6
Evans, R.M.7
-
11
-
-
0037394603
-
Potentiation of liver X receptor transcriptional activity by peroxisome-proliferator-activated receptor gamma co-activator 1alpha
-
DOI 10.1042/BJ20021665
-
Oberkofler H, Schraml E, Krempler F, Patsch W (2003) Potentiation of liver X receptor transcriptional activity by peroxisome-proliferator-activated receptor gamma co-activator 1 alpha. Biochem J 371:89-96 (Pubitemid 36458082)
-
(2003)
Biochemical Journal
, vol.371
, Issue.1
, pp. 89-96
-
-
Oberkofler, H.1
Schraml, E.2
Krempler, F.3
Patsch, W.4
-
12
-
-
0942279602
-
Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR
-
DOI 10.1101/gad.1138104
-
Zhang Y, Castellani LW, Sinal CJ, Gonzalez FJ, Edwards PA (2004) Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR. Genes Dev 18:157-169 (Pubitemid 38141784)
-
(2004)
Genes and Development
, vol.18
, Issue.2
, pp. 157-169
-
-
Zhang, Y.1
Castellani, L.W.2
Sinal, C.J.3
Gonzalez, F.J.4
Edwards, P.A.5
-
13
-
-
23044438299
-
Coactivation of the human vitamin D receptor by the peroxisome proliferator-activated receptor gamma coactivator-1 alpha
-
DOI 10.1124/mol.105.012708
-
Savkur RS, Bramlett KS, Stayrook KR, Nagpal S, Burris TP (2005) Coactivation of the human vitamin D receptor by the peroxisome proliferator-activated receptor gamma coactivator-1 alpha. Mol Pharmacol 68:511-517 (Pubitemid 41058314)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.2
, pp. 511-517
-
-
Savkur, R.S.1
Bramlett, K.S.2
Stayrook, K.R.3
Nagpal, S.4
Burris, T.P.5
-
14
-
-
0038514189
-
Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor gamma coactivator-1alpha: A possible link between xenobiotic response and nutritional state
-
DOI 10.1074/jbc.M212859200
-
Shiraki T, Sakai N, Kanaya E, Jingami H (2003) Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor gamma coactivator-1 alpha, a possible link between xenobiotic response and nutritional state. J Biol Chem 278:11344-11350 (Pubitemid 36792692)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.13
, pp. 11344-11350
-
-
Shiraki, T.1
Sakai, N.2
Kanaya, E.3
Jingami, H.4
-
15
-
-
7244243931
-
Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism
-
DOI 10.1074/jbc.M405423200
-
Bhalla S, Ozalp C, Fang S, Xiang L, Kemper JK (2004) Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha, functional implications in hepatic cholesterol and glucose metabolism. J Biol Chem 279:45139-45147 (Pubitemid 39430929)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.43
, pp. 45139-45147
-
-
Bhalla, S.1
Ozalp, C.2
Fang, S.3
Xiang, L.4
Kemper, J.K.5
-
16
-
-
0034717075
-
Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1
-
DOI 10.1074/jbc.M001364200
-
Tcherepanova I, Puigserver P, Norris JD, Spiegelman BM, McDonnell DP (2000) Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1. J Biol Chem 275: 16302-16308 (Pubitemid 30366945)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.21
, pp. 16302-16308
-
-
Tcherepanova, I.1
Puigserver, P.2
Norris, J.D.3
Spiegelman, B.M.4
McDonnell, D.P.5
-
17
-
-
0037174798
-
Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma: Identification of novel Leucine-rich interaction motif within PGC-1alpha
-
DOI 10.1074/jbc.M206324200
-
Huss JM, Kopp RP, Kelly DP (2002) Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha. J Biol Chem 277:40265-40274 (Pubitemid 35215598)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.43
, pp. 40265-40274
-
-
Huss, J.M.1
Kopp, R.P.2
Kelly, D.P.3
-
18
-
-
0035855858
-
Control of hepatic gluconeogenesis through the transcriptional coaotivator PGC-1
-
DOI 10.1038/35093050
-
Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, Newgard CB, Spiegelman BM (2001) Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413:131-138 (Pubitemid 32867868)
-
(2001)
Nature
, vol.413
, Issue.6852
, pp. 131-138
-
-
Yoon, J.C.1
Puigserver, P.2
Chen, G.3
Donovan, J.4
Wu, Z.5
Rhee, J.6
Adelmant, G.7
Stafford, J.8
Kahn, C.R.9
Granner, D.K.10
Newgard, C.B.11
Spiegelman, B.M.12
-
19
-
-
0242349197
-
Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): Requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis
-
DOI 10.1073/pnas.0730870100
-
Rhee J, Inoue Y, Yoon JC, Puigserver P, Fan M, Gonzalez FJ, Spiegelman BM (2003) Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. Proc Natl Acad Sci U S A 100:4012-4017 (Pubitemid 36418148)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 4012-4017
-
-
Rhee, J.1
Inoue, Y.2
Yoon, J.C.3
Puigserver, P.4
Fan, M.5
Gonzalez, F.J.6
Spiegelman, B.M.7
-
20
-
-
0037040253
-
PGC-1 functions as a transcriptional coactivator for the retinoid X receptors
-
DOI 10.1074/jbc.M109409200
-
Delerive P, Wu Y, Burris TP, Chin WW, Suen CS (2002) PGC-1 functions as a transcriptional coactivator for the retinoid X receptors. J Biol Chem 277:3913-3917 (Pubitemid 34968643)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.6
, pp. 3913-3917
-
-
Delerive, P.1
Wu, Y.2
Burris, T.P.3
Chin, W.W.4
Suen, C.S.5
-
21
-
-
0034116143
-
A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen
-
DOI 10.1128/MCB.20.7.2411-2422.2000
-
Knutti D, Kaul A, Kralli A (2000) A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen. Mol Cell Biol 20:2411-2422 (Pubitemid 30152049)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.7
, pp. 2411-2422
-
-
Knutti, D.1
Kaul, A.2
Kralli, A.3
-
22
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
-
DOI 10.1038/nature01667
-
Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D, Spiegelman BM (2003) Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature 423:550-555 (Pubitemid 36648580)
-
(2003)
Nature
, vol.423
, Issue.6939
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
Walkey, C.J.4
Yoon, J.C.5
Oriente, F.6
Kitamura, Y.7
Altomonte, J.8
Dong, H.9
Accili, D.10
Spiegelman, B.M.11
-
23
-
-
67649819237
-
Mutual dependence of Foxo3a and PGC-1alpha in the induction of oxidative stress genes
-
Olmos Y, Valle I, Borniquel S, Tierrez A, Soria E, Lamas S, Monsalve M (2009) Mutual dependence of Foxo3a and PGC-1alpha in the induction of oxidative stress genes. J Biol Chem 284:14476-14484
-
(2009)
J Biol Chem
, vol.284
, pp. 14476-14484
-
-
Olmos, Y.1
Valle, I.2
Borniquel, S.3
Tierrez, A.4
Soria, E.5
Lamas, S.6
Monsalve, M.7
-
24
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
DOI 10.1016/S0092-8674(00)80611-X
-
Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC, Spiegelman BM(1999) Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98:115-124 (Pubitemid 29331201)
-
(1999)
Cell
, vol.98
, Issue.1
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
Mootha, V.6
Troy, A.7
Cinti, S.8
Lowell, B.9
Scarpulla, R.C.10
Spiegelman, B.M.11
-
25
-
-
0038269020
-
Upstream stimulatory factor represses the induction of carnitine palmitoyltransferase-Ibeta expression by PGC-1
-
DOI 10.1074/jbc.M210486200
-
Moore ML, Park EA, McMillin JB (2003) Upstream stimulatory factor represses the induction of carnitine palmitoyltransferase-Ibeta expression by PGC-1. J Biol Chem 278:17263-17268 (Pubitemid 36799608)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.19
, pp. 17263-17268
-
-
Moore, M.L.1
Park, E.A.2
McMillin, J.B.3
-
26
-
-
0035957375
-
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
-
DOI 10.1073/pnas.061035098
-
Michael LF, Wu Z, Cheatham RB, Puigserver P, Adelmant G, Lehman JJ, Kelly DP, Spiegelman BM (2001) Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proc Natl Acad Sci U S A 98:3820-3825 (Pubitemid 32249855)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.7
, pp. 3820-3825
-
-
Michael, L.F.1
Wu, Z.2
Cheatham, R.B.3
Puigserver, P.4
Adelmant, G.5
Lehman, J.J.6
Kelly, D.P.7
Spiegelman, B.M.8
-
27
-
-
0037127204
-
Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta), a novel PGC-1-related transcription coactivator associated with host cell factor
-
DOI 10.1074/jbc.C100631200
-
Lin J, Puigserver P, Donovan J, Tarr P, Spiegelman BM (2002) Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta), a novel PGC-1-related transcription coactivator associated with host cell factor. J Biol Chem 277:1645-1648 (Pubitemid 34968733)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.3
, pp. 1645-1648
-
-
Lin, J.1
Puigserver, P.2
Donovan, J.3
Tarr, P.4
Spiegelman, B.M.5
-
28
-
-
0037134493
-
The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha
-
DOI 10.1074/jbc.M201134200
-
Kressler D, Schreiber SN, Knutti D, Kralli A (2002) The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha. J Biol Chem 277:13918-13925 (Pubitemid 34967998)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.16
, pp. 13918-13925
-
-
Kressler, D.1
Schreiber, S.N.2
Knutti, D.3
Kralli, A.4
-
29
-
-
0142091356
-
PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity
-
DOI 10.1073/pnas.2135217100
-
Kamei Y, Ohizumi H, Fujitani Y, Nemoto T, Tanaka T, Takahashi N, Kawada T, Miyoshi M, Ezaki O, Kakizuka A (2003) PPAR{gamma} coactivator 1{beta}/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity. Proc Natl Acad Sci U S A 100:12378-12383 (Pubitemid 37271568)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.21
, pp. 12378-12383
-
-
Kamei, Y.1
Ohizumi, H.2
Fujitani, Y.3
Nemoto, T.4
Tanaka, T.5
Takahashi, N.6
Kawada, T.7
Miyoshi, M.8
Ezaki, O.9
Kakizuka, A.10
-
30
-
-
0036921549
-
PGC-1 and PERC, coactivators of the estrogen receptor-related receptor gamma
-
DOI 10.1016/S0006-291X(02)02753-5, PII S0006291X02027535
-
Hentschke M, Susens U, Borgmeyer U (2002) PGC-1 and PERC, coactivators of the estrogen receptor-related receptor gamma. Biochem Biophys Res Commun 299:872-879 (Pubitemid 36034567)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.299
, Issue.5
, pp. 872-879
-
-
Hentschke, M.1
Susens, U.2
Borgmeyer, U.3
-
31
-
-
19944430411
-
Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP
-
DOI 10.1016/j.cell.2004.11.043, PII S009286740401147X
-
Lin J, Yang R, Tarr PT, Wu PH, Handschin C, Li S, Yang W, Pei L, Uldry M, Tontonoz P, Newgard CB, Spiegelman BM (2005) Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP. Cell 120:261-273 (Pubitemid 40174768)
-
(2005)
Cell
, vol.120
, Issue.2
, pp. 261-273
-
-
Lin, J.1
Yang, R.2
Tarr, P.T.3
Wu, P.-H.4
Handschin, C.5
Li, S.6
Yang, W.7
Pei, L.8
Uldry, M.9
Tontonoz, P.10
Newgard, C.B.11
Spiegelman, B.M.12
-
32
-
-
60549086405
-
Transcriptional co-activator peroxisome proliferator-activated receptor (PPAR)gamma co-activator-1beta is involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells
-
Oberkofler H, Hafner M, Felder T, Krempler F, Patsch W (2009) Transcriptional co-activator peroxisome proliferator-activated receptor (PPAR)gamma co-activator-1beta is involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells. J Mol Med 87:299-306
-
(2009)
J Mol Med
, vol.87
, pp. 299-306
-
-
Oberkofler, H.1
Hafner, M.2
Felder, T.3
Krempler, F.4
Patsch, W.5
-
33
-
-
32444451567
-
Coactivation of Foxa2 through Pgc-1beta promotes liver fatty acid oxidation and triglyceride/VLDL secretion
-
Wolfrum C, Stoffel M (2006) Coactivation of Foxa2 through Pgc-1beta promotes liver fatty acid oxidation and triglyceride/VLDL secretion. Cell Metab 3:99-110
-
(2006)
Cell Metab
, vol.3
, pp. 99-110
-
-
Wolfrum, C.1
Stoffel, M.2
-
34
-
-
75149134754
-
Estrogen-related receptor alpha and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria
-
Mirebeau-Prunier D, Le Pennec S, Jacques C, Gueguen N, Poirier J, Malthiery Y, Savagner F (2010) Estrogen-related receptor alpha and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria. FEBS J 277:713-725
-
(2010)
FEBS J
, vol.277
, pp. 713-725
-
-
Mirebeau-Prunier, D.1
Le Pennec, S.2
Jacques, C.3
Gueguen, N.4
Poirier, J.5
Malthiery, Y.6
Savagner, F.7
-
35
-
-
0035016566
-
PGC-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells
-
DOI 10.1128/MCB.21.11.3738-3749.2001
-
Andersson U, Scarpulla RC (2001) Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells. Mol Cell Biol 21:3738-3749 (Pubitemid 32466987)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.11
, pp. 3738-3749
-
-
Andersson, U.1
Scarpulla, R.C.2
-
36
-
-
0032589689
-
Activation of PPARgamma coactivator-1 through transcription factor docking
-
Puigserver P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B, Spiegelman BM (1999) Activation of PPARgamma coactivator-1 through transcription factor docking. Science 286:1368-1371
-
(1999)
Science
, vol.286
, pp. 1368-1371
-
-
Puigserver, P.1
Adelmant, G.2
Wu, Z.3
Fan, M.4
Xu, J.5
O'Malley, B.6
Spiegelman, B.M.7
-
37
-
-
48349108293
-
Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism
-
Li S, Liu C, Li N, Hao T, Han T, Hill DE, Vidal M, Lin JD (2008) Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism. Cell Metab 8:105-117
-
(2008)
Cell Metab
, vol.8
, pp. 105-117
-
-
Li, S.1
Liu, C.2
Li, N.3
Hao, T.4
Han, T.5
Hill, D.E.6
Vidal, M.7
Lin, J.D.8
-
38
-
-
0344413490
-
Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha
-
DOI 10.1016/S1097-2765(03)00391-5
-
Wallberg AE, Yamamura S, Malik S, Spiegelman BM, Roeder RG (2003) Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha. Mol Cell 12:1137-1149 (Pubitemid 37487924)
-
(2003)
Molecular Cell
, vol.12
, Issue.5
, pp. 1137-1149
-
-
Wallberg, A.E.1
Yamamura, S.2
Malik, S.3
Spiegelman, B.M.4
Roeder, R.G.5
-
39
-
-
0037147304
-
Glucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHP
-
DOI 10.1074/jbc.M205641200
-
Borgius LJ, Steffensen KR, Gustafsson JA, Treuter E (2002) Glucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHP. J Biol Chem 277:49761-49766 (Pubitemid 36014422)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.51
, pp. 49761-49766
-
-
Borgius, L.J.1
Steffensen, K.R.2
Gustafsson, J.-A.3
Treuter, E.4
-
40
-
-
70350371629
-
Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation
-
Xie YB, Park JH, Kim DK, Hwang JH, Oh S, Park SB, Shong M, Lee IK, Choi HS (2009) Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. J Biol Chem 284:28762-28774
-
(2009)
J Biol Chem
, vol.284
, pp. 28762-28774
-
-
Xie, Y.B.1
Park, J.H.2
Kim, D.K.3
Hwang, J.H.4
Oh, S.5
Park, S.B.6
Shong, M.7
Lee, I.K.8
Choi, H.S.9
-
41
-
-
29244434047
-
An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRgamma
-
DOI 10.1093/nar/gki976
-
Park YY, Ahn SW, Kim HJ, Kim JM, Lee IK, Kang H, Choi HS (2005) An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRgamma. Nucleic Acids Res 33:6756-6768 (Pubitemid 41830482)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.21
, pp. 6756-6768
-
-
Park, Y.-Y.1
Ahn, S.-W.2
Kim, H.-J.3
Kim, J.-M.4
Lee, I.-K.5
Kang, H.6
Choi, H.-S.7
-
42
-
-
70350463602
-
DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expression
-
Nedumaran B, Hong S, Xie YB, Kim YH, Seo WY, Lee MW, Lee CH, Koo SH, Choi HS (2009) DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expression. J Biol Chem 284:27511-27523
-
(2009)
J Biol Chem
, vol.284
, pp. 27511-27523
-
-
Nedumaran, B.1
Hong, S.2
Xie, Y.B.3
Kim, Y.H.4
Seo, W.Y.5
Lee, M.W.6
Lee, C.H.7
Koo, S.H.8
Choi, H.S.9
-
43
-
-
0033638283
-
Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
-
Monsalve M, Wu Z, Adelmant G, Puigserver P, Fan M, Spiegelman BM (2000) Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol Cell 6:307-316
-
(2000)
Mol Cell
, vol.6
, pp. 307-316
-
-
Monsalve, M.1
Wu, Z.2
Adelmant, G.3
Puigserver, P.4
Fan, M.5
Spiegelman, B.M.6
-
44
-
-
0038682372
-
Characterization of the human, mouse and rat PGC1beta (peroxisomeproliferator-activated receptor-gamma co-activator 1beta) gene in vitro and in vivo
-
DOI 10.1042/BJ20030200
-
Meirhaeghe A, Crowley V, Lenaghan C, Lelliott C, Green K, Stewart A, Hart K, Schinner S, Sethi JK, Yeo G, Brand MD, Cortright RN, O'Rahilly S, Montague C, Vidal-Puig AJ (2003) Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo. Biochem J 373:155-165 (Pubitemid 36819511)
-
(2003)
Biochemical Journal
, vol.373
, Issue.1
, pp. 155-165
-
-
Meirhaeghe, A.1
Crowley, V.2
Lenaghan, C.3
Lelliott, C.4
Green, K.5
Stewart, A.6
Hart, K.7
Schinner, S.8
Sethi, J.K.9
Yeo, G.10
Brand, M.D.11
Cortright, R.N.12
O'Rahilly, S.13
Montague, C.14
Vidal-Puig, A.J.15
-
45
-
-
70450252013
-
Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha
-
Zhang Y, Huypens P, Adamson AW, Chang JS, Henagan TM, Boudreau A, Lenard NR, Burk D, Klein J, Perwitz N, Shin J, Fasshauer M, Kralli A, Gettys TW (2009) Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha. J Biol Chem 284:32813-32826
-
(2009)
J Biol Chem
, vol.284
, pp. 32813-32826
-
-
Zhang, Y.1
Huypens, P.2
Adamson, A.W.3
Chang, J.S.4
Henagan, T.M.5
Boudreau, A.6
Lenard, N.R.7
Burk, D.8
Klein, J.9
Perwitz, N.10
Shin, J.11
Fasshauer, M.12
Kralli, A.13
Gettys, T.W.14
-
46
-
-
62649165344
-
Identification and characterization of an alternative promoter of the human PGC-1alpha gene
-
Yoshioka T, Inagaki K, Noguchi T, Sakai M, Ogawa W, Hosooka T, Iguchi H, Watanabe E, Matsuki Y, Hiramatsu R, Kasuga M (2009) Identification and characterization of an alternative promoter of the human PGC-1alpha gene. Biochem Biophys Res Commun 381:537-543
-
(2009)
Biochem Biophys Res Commun
, vol.381
, pp. 537-543
-
-
Yoshioka, T.1
Inagaki, K.2
Noguchi, T.3
Sakai, M.4
Ogawa, W.5
Hosooka, T.6
Iguchi, H.7
Watanabe, E.8
Matsuki, Y.9
Hiramatsu, R.10
Kasuga, M.11
-
47
-
-
50449102941
-
Isoform-specific increases in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to beta2-adrenergic receptor activation and exercise
-
Miura S, Kai Y, Kamei Y, Ezaki O (2008) Isoform-specific increases in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to beta2-adrenergic receptor activation and exercise. Endocrinology 149:4527-4533
-
(2008)
Endocrinology
, vol.149
, pp. 4527-4533
-
-
Miura, S.1
Kai, Y.2
Kamei, Y.3
Ezaki, O.4
-
48
-
-
84870921992
-
A PGC-1alpha isoform induced by resistance training regulates skeletal muscle hypertrophy
-
Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, Leinwand LA, Spiegelman BM (2012) A PGC-1alpha isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell 151:1319-1331
-
(2012)
Cell
, vol.151
, pp. 1319-1331
-
-
Ruas, J.L.1
White, J.P.2
Rao, R.R.3
Kleiner, S.4
Brannan, K.T.5
Harrison, B.C.6
Greene, N.P.7
Wu, J.8
Estall, J.L.9
Irving, B.A.10
Lanza, I.R.11
Rasbach, K.A.12
Okutsu, M.13
Nair, K.S.14
Yan, Z.15
Leinwand, L.A.16
Spiegelman, B.M.17
-
49
-
-
0035855905
-
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
-
DOI 10.1038/35093131
-
Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M (2001) CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 413:179-183 (Pubitemid 32867880)
-
(2001)
Nature
, vol.413
, Issue.6852
, pp. 179-183
-
-
Herzig, S.1
Long, F.2
Jhala, U.S.3
Hedrick, S.4
Quinn, R.5
Bauer, A.6
Rudolph, D.7
Schutz, G.8
Yoon, C.9
Puigserver, P.10
Spiegelman, B.11
Montminy, M.12
-
50
-
-
0038810035
-
An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle
-
DOI 10.1073/pnas.1232352100
-
Handschin C, Rhee J, Lin J, Tarr PT, Spiegelman BM (2003) An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle. Proc Natl Acad Sci U S A 100:7111-7116 (Pubitemid 36706401)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.12
, pp. 7111-7116
-
-
Handschin, C.1
Rhee, J.2
Lin, J.3
Tarr, P.T.4
Spiegelman, B.M.5
-
51
-
-
30044436829
-
p38 mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis
-
DOI 10.1074/jbc.M506223200
-
Cao W, Collins QF, Becker TC, Robidoux J, Lupo EG Jr, Xiong Y, Daniel KW, Floering L, Collins S (2005) p38 mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis. J Biol Chem 280:42731-42737 (Pubitemid 43049233)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.52
, pp. 42731-42737
-
-
Cao, W.1
Collins, Q.F.2
Becker, T.C.3
Robidoux, J.4
Lupo Jr., E.G.5
Xiong, Y.6
Daniel, K.W.7
Floering, L.8
Collins, S.9
-
52
-
-
21244477127
-
Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway
-
DOI 10.1074/jbc.M408862200
-
Akimoto T, Pohnert SC, Li P, Zhang M, Gumbs C, Rosenberg PB, Williams RS, Yan Z (2005) Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway. J Biol Chem 280:19587-19593 (Pubitemid 41379480)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.20
, pp. 19587-19593
-
-
Akimoto, T.1
Pohnert, S.C.2
Li, P.3
Zhang, M.4
Gumbs, C.5
Rosenberg, P.B.6
Williams, R.S.7
Yan, Z.8
-
53
-
-
34547545892
-
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
-
DOI 10.1073/pnas.0705070104
-
Jager S, Handschin C, St-Pierre J, Spiegelman BM (2007) AMP-activated protein kinase (AMPK) action in skeletalmuscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci U S A 104: 12017-12022 (Pubitemid 47185622)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.29
, pp. 12017-12022
-
-
Jaer, S.1
Handschin, C.2
St-Pierre, J.3
Spiegelman, B.M.4
-
54
-
-
33646782581
-
Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1alpha gene transcription: An autoregulatory loop controls PGC-1alpha expression in adipocytes via peroxisome proliferator- activated receptor-gamma coactivation
-
DOI 10.1210/en.2006-0070
-
Hondares E, Mora O, Yubero P, de la Concepcion MR, Iglesias R, Giralt M, Villarroya F (2006) Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1alpha gene transcription: an autoregulatory loop controls PGC-1alpha expression in adipocytes via peroxisome proliferator-activated receptor-gamma coactivation. Endocrinology 147:2829-2838 (Pubitemid 43764595)
-
(2006)
Endocrinology
, vol.147
, Issue.6
, pp. 2829-2838
-
-
Hondares, E.1
Mora, O.2
Yubero, P.3
De La, C.M.R.4
Iglesias, R.5
Giralt, M.6
Villarroya, F.7
-
55
-
-
83355163350
-
Peroxisome proliferator-activated receptor alpha (PPARalpha) induces PPARgamma coactivator 1alpha (PGC-1alpha) gene expression and contributes to thermogenic activation of brown fat: Involvement of PRDM16
-
Hondares E, Rosell M, Diaz-Delfin J, Olmos Y, Monsalve M, Iglesias R, Villarroya F, Giralt M (2011) Peroxisome proliferator-activated receptor alpha (PPARalpha) induces PPARgamma coactivator 1alpha (PGC-1alpha) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16. J Biol Chem 286:43112-43122
-
(2011)
J Biol Chem
, vol.286
, pp. 43112-43122
-
-
Hondares, E.1
Rosell, M.2
Diaz-Delfin, J.3
Olmos, Y.4
Monsalve, M.5
Iglesias, R.6
Villarroya, F.7
Giralt, M.8
-
56
-
-
0037342151
-
Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR
-
DOI 10.2337/diabetes.52.3.642
-
Daitoku H, Yamagata K, Matsuzaki H, Hatta M, Fukamizu A (2003) Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR. Diabetes 52:642-649 (Pubitemid 36323569)
-
(2003)
Diabetes
, vol.52
, Issue.3
, pp. 642-649
-
-
Daitoku, H.1
Yamagata, K.2
Matsuzaki, H.3
Hatta, M.4
Fukamizu, A.5
-
57
-
-
0037452677
-
Regulation of peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) and mitochondrial function by MEF2 and HDAC5
-
DOI 10.1073/pnas.0337639100
-
Czubryt MP, McAnally J, Fishman GI, Olson EN (2003) Regulation of peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) and mitochondrial function by MEF2 and HDAC5. Proc Natl Acad Sci U S A 100:1711-1716 (Pubitemid 36254513)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.4
, pp. 1711-1716
-
-
Czubryt, M.P.1
McAnally, J.2
Fishman, G.I.3
Olson, E.N.4
-
58
-
-
27844551588
-
The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes
-
Wang L, Liu J, Saha P, Huang J, Chan L, Spiegelman B, Moore DD (2005) The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes. Cell Metab 2:227-238
-
(2005)
Cell Metab
, vol.2
, pp. 227-238
-
-
Wang, L.1
Liu, J.2
Saha, P.3
Huang, J.4
Chan, L.5
Spiegelman, B.6
Moore, D.D.7
-
59
-
-
70349142240
-
Negative feedback maintenance of heme homeostasis by its receptor, Reverbalpha
-
Wu N, Yin L, Hanniman EA, Joshi S, Lazar MA (2009) Negative feedback maintenance of heme homeostasis by its receptor, Reverbalpha. Genes Dev 23:2201-2209
-
(2009)
Genes Dev
, vol.23
, pp. 2201-2209
-
-
Wu, N.1
Yin, L.2
Hanniman, E.A.3
Joshi, S.4
Lazar, M.A.5
-
60
-
-
69149087790
-
Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density
-
Barres R, Osler ME, Yan J, Rune A, Fritz T, Caidahl K, Krook A, Zierath JR (2009) Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density. Cell Metab 10:189-198
-
(2009)
Cell Metab
, vol.10
, pp. 189-198
-
-
Barres, R.1
Osler, M.E.2
Yan, J.3
Rune, A.4
Fritz, T.5
Caidahl, K.6
Krook, A.7
Zierath, J.R.8
-
61
-
-
18244399631
-
Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPARgamma Coactivator-1
-
DOI 10.1016/S1097-2765(01)00390-2
-
Puigserver P, Rhee J, Lin J, Wu Z, Yoon JC, Zhang C-Y, Krauss S, Mootha VK, Lowell BB, Spiegelman BM (2001) Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. Mol Cell 8:971-982 (Pubitemid 34031800)
-
(2001)
Molecular Cell
, vol.8
, Issue.5
, pp. 971-982
-
-
Puigserver, P.1
Rhee, J.2
Lin, J.3
Wu, Z.4
Yoon J.Cliff5
Zhang, C.-Y.6
Krauss, S.7
Mootha, V.K.8
Lowell, B.B.9
Spiegelman, B.M.10
-
62
-
-
10744222588
-
Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: Modulation by p38 MAPK
-
DOI 10.1101/gad.1152204
-
Fan M, Rhee J, St-Pierre J, Handschin C, Puigserver P, Lin J, Jaeger S, Erdjument-Bromage H, Tempst P, Spiegelman BM (2004) Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. Genes Dev 18:278-289 (Pubitemid 38199253)
-
(2004)
Genes and Development
, vol.18
, Issue.3
, pp. 278-289
-
-
Fan, M.1
Rhee, J.2
St-Pierre, J.3
Handschin, C.4
Puigserver, P.5
Lin, J.6
Jaeger, S.7
Erdjument-Bromage, H.8
Tempst, P.9
Spiegelman, B.M.10
-
63
-
-
77952931582
-
Regulation of NT-PGC-1alpha subcellular localization and function by protein kinase A-dependent modulation of nuclear export by CRM1
-
Chang JS, Huypens P, Zhang Y, Black C, Kralli A, Gettys TW (2010) Regulation of NT-PGC-1alpha subcellular localization and function by protein kinase A-dependent modulation of nuclear export by CRM1. J Biol Chem 285:18039-18050
-
(2010)
J Biol Chem
, vol.285
, pp. 18039-18050
-
-
Chang, J.S.1
Huypens, P.2
Zhang, Y.3
Black, C.4
Kralli, A.5
Gettys, T.W.6
-
64
-
-
34250740323
-
Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator
-
DOI 10.1038/nature05861, PII NATURE05861
-
Li X, Monks B, Ge Q, Birnbaum MJ (2007) Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator. Nature 447:1012-1016 (Pubitemid 46975750)
-
(2007)
Nature
, vol.447
, Issue.7147
, pp. 1012-1016
-
-
Li, X.1
Monks, B.2
Ge, Q.3
Birnbaum, M.J.4
-
65
-
-
38349130508
-
Dynamic regulation of PGC-1alpha localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response
-
Anderson RM, Barger JL, Edwards MG, Braun KH, O'Connor CE, Prolla TA, Weindruch R (2008) Dynamic regulation of PGC-1alpha localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response. Aging Cell 7:101-111
-
(2008)
Aging Cell
, vol.7
, pp. 101-111
-
-
Anderson, R.M.1
Barger, J.L.2
Edwards, M.G.3
Braun, K.H.4
O'Connor, C.E.5
Prolla, T.A.6
Weindruch, R.7
-
66
-
-
38349057556
-
SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis
-
Olson BL, Hock MB, Ekholm-Reed S, Wohlschlegel JA, Dev KK, Kralli A, Reed SI (2008) SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis. Genes Dev 22:252-264
-
(2008)
Genes Dev
, vol.22
, pp. 252-264
-
-
Olson, B.L.1
Hock, M.B.2
Ekholm-Reed, S.3
Wohlschlegel, J.A.4
Dev, K.K.5
Kralli, A.6
Reed, S.I.7
-
67
-
-
33744534726
-
GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha
-
DOI 10.1016/j.cmet.2006.04.013, PII S1550413106001537
-
Lerin C, Rodgers JT, Kalume DE, Kim SH, Pandey A, Puigserver P (2006) GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha. Cell Metab 3:429-438 (Pubitemid 43811779)
-
(2006)
Cell Metabolism
, vol.3
, Issue.6
, pp. 429-438
-
-
Lerin, C.1
Rodgers, J.T.2
Kalume, D.E.3
Kim, S.-h.4
Pandey, A.5
Puigserver, P.6
-
68
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
DOI 10.1038/nature03354
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P (2005) Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434:113-118 (Pubitemid 40349395)
-
(2005)
Nature
, vol.434
, Issue.7029
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
69
-
-
18144411313
-
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1alpha
-
DOI 10.1074/jbc.M501485200
-
Nemoto S, Fergusson MM, Finkel T (2005) SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}. J Biol Chem 280:16456-16460 (Pubitemid 40616776)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.16
, pp. 16456-16460
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
70
-
-
64549127790
-
PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
-
Canto C, Auwerx J (2009) PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure. Curr Opin Lipidol 20:98-105
-
(2009)
Curr Opin Lipidol
, vol.20
, pp. 98-105
-
-
Canto, C.1
Auwerx, J.2
-
71
-
-
70350031566
-
SUMOylation attenuates the function of PGC-1alpha
-
Rytinki MM, Palvimo JJ (2009) SUMOylation attenuates the function of PGC-1alpha. J Biol Chem 284:26184-26193
-
(2009)
J Biol Chem
, vol.284
, pp. 26184-26193
-
-
Rytinki, M.M.1
Palvimo, J.J.2
-
72
-
-
55849147331
-
A functional interaction between RIP140 and PGC-1alpha regulates the expression of the lipid droplet protein CIDEA
-
Hallberg M, Morganstein DL, Kiskinis E, Shah K, Kralli A, Dilworth SM, White R, Parker MG, Christian M (2008) A functional interaction between RIP140 and PGC-1alpha regulates the expression of the lipid droplet protein CIDEA. Mol Cell Biol 28:6785-6795
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6785-6795
-
-
Hallberg, M.1
Morganstein, D.L.2
Kiskinis, E.3
Shah, K.4
Kralli, A.5
Dilworth, S.M.6
White, R.7
Parker, M.G.8
Christian, M.9
-
73
-
-
64149111641
-
A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose
-
Housley MP, Udeshi ND, Rodgers JT, Shabanowitz J, Puigserver P, Hunt DF, Hart GW (2009) A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose. J Biol Chem 284:5148-5157
-
(2009)
J Biol Chem
, vol.284
, pp. 5148-5157
-
-
Housley, M.P.1
Udeshi, N.D.2
Rodgers, J.T.3
Shabanowitz, J.4
Puigserver, P.5
Hunt, D.F.6
Hart, G.W.7
-
74
-
-
22344440666
-
Activation of nuclear receptor coactivator PGC-1alpha by arginine methylation
-
DOI 10.1101/gad.1295005
-
Teyssier C, Ma H, Emter R, Kralli A, Stallcup MR (2005) Activation of nuclear receptor coactivator PGC-1alpha by arginine methylation. Genes Dev 19:1466-1473 (Pubitemid 41003013)
-
(2005)
Genes and Development
, vol.19
, Issue.12
, pp. 1466-1473
-
-
Teyssier, C.1
Ma, H.2
Emter, R.3
Kralli, A.4
Stallcup, M.R.5
-
76
-
-
75649131899
-
The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling
-
Tiefenbock SK, Baltzer C, Egli NA, Frei C (2009) The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling. Embo J 29:171-183
-
(2009)
Embo J
, vol.29
, pp. 171-183
-
-
Tiefenbock, S.K.1
Baltzer, C.2
Egli, N.A.3
Frei, C.4
-
77
-
-
2342592545
-
The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis
-
DOI 10.1073/pnas.0308686101
-
Schreiber SN, Emter R, Hock MB, Knutti D, Cardenas J, Podvinec M, Oakeley EJ, Kralli A (2004) The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis. Proc Natl Acad Sci U S A 101:6472-6477 (Pubitemid 38585998)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.17
, pp. 6472-6477
-
-
Schreiber, S.N.1
Emter, R.2
Hock, M.B.3
Knutti, D.4
Cardenas, J.5
Podvinec, M.6
Oakeley, E.J.7
Kralli, A.8
-
78
-
-
0038660688
-
The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha)
-
DOI 10.1074/jbc.M212923200
-
Schreiber SN, Knutti D, Brogli K, Uhlmann T, Kralli A (2003) The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha). J Biol Chem 278:9013-9018 (Pubitemid 36800379)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.11
, pp. 9013-9018
-
-
Schreiber, S.N.1
Knutti, D.2
Brogli, K.3
Uhlmann, T.4
Kralli, A.5
-
79
-
-
2342477730
-
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle
-
DOI 10.1073/pnas.0401401101
-
Mootha VK, Handschin C, Arlow D, Xie X, St Pierre J, Sihag S, Yang W, Altshuler D, Puigserver P, Patterson N, Willy PJ, Schulman IG, Heyman RA, Lander ES, Spiegelman BM (2004) Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proc Natl Acad Sci U S A 101:6570-6575 (Pubitemid 38586015)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.17
, pp. 6570-6575
-
-
Mootha, V.K.1
Handschin, C.2
Arlow, D.3
Xie, X.4
St., P.J.5
Sihag, S.6
Yang, W.7
Altshuler, D.8
Puigserver, P.9
Patterson, N.10
Willy, P.J.11
Schulman, I.G.12
Heyman, R.A.13
Lander, E.S.14
Spiegelman, B.M.15
-
80
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
-
DOI 10.1016/j.cell.2004.09.013, PII S0092867404008864
-
Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, Zhang CY, Mootha VK, Jager S, Vianna CR, Reznick RM, Cui L, Manieri M, Donovan MX, Wu Z, Cooper MP, Fan MC, Rohas LM, Zavacki AM, Cinti S, Shulman GI, Lowell BB, Krainc D, Spiegelman BM (2004) Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell 119:121-135 (Pubitemid 39349325)
-
(2004)
Cell
, vol.119
, Issue.1
, pp. 121-135
-
-
Lin, J.1
Wu, P.-H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
Zhang, C.-Y.6
Mootha, V.K.7
Jager, S.8
Vianna, C.R.9
Reznick, R.M.10
Cui, L.11
Manieri, M.12
Donovan, M.X.13
Wu, Z.14
Cooper, M.P.15
Fan, M.C.16
Rohas, L.M.17
Zavacki, A.M.18
Cinti, S.19
Shulman, G.I.20
Lowell, B.B.21
Krainc, D.22
Spiegelman, B.M.23
more..
-
81
-
-
21144446106
-
PGC-1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis
-
Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED, Semenkovich CF, Kelly DP (2005) PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol 3:e101
-
(2005)
PLoS Biol
, vol.3
-
-
Leone, T.C.1
Lehman, J.J.2
Finck, B.N.3
Schaeffer, P.J.4
Wende, A.R.5
Boudina, S.6
Courtois, M.7
Wozniak, D.F.8
Sambandam, N.9
Bernal-Mizrachi, C.10
Chen, Z.11
Holloszy, J.O.12
Medeiros, D.M.13
Schmidt, R.E.14
Saffitz, J.E.15
Abel, E.D.16
Semenkovich, C.F.17
Kelly, D.P.18
-
82
-
-
34247590356
-
PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis
-
DOI 10.1073/pnas.0611623104
-
Sonoda J, Mehl IR, Chong LW, Nofsinger RR, Evans RM (2007) PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis. Proc Natl Acad Sci U S A 104:5223-5228 (Pubitemid 47186203)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.12
, pp. 5223-5228
-
-
Sonoda, J.1
Mehl, I.R.2
Chong, L.-W.3
Nofsinger, R.R.4
Evans, R.M.5
-
83
-
-
33751022208
-
Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance
-
Lelliott CJ, Medina-Gomez G, Petrovic N, Kis A, Feldmann HM, Bjursell M, Parker N, Curtis K, Campbell M, Hu P, Zhang D, Litwin SE, Zaha VG, Fountain KT, Boudina S, Jimenez-Linan M, Blount M, Lopez M, Meirhaeghe A, Bohlooly YM, Storlien L, Stromstedt M, Snaith M, Oresic M, Abel ED, Cannon B, Vidal-Puig A (2006) Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance. PLoS Biol 4:e369
-
(2006)
PLoS Biol
, vol.4
-
-
Lelliott, C.J.1
Medina-Gomez, G.2
Petrovic, N.3
Kis, A.4
Feldmann, H.M.5
Bjursell, M.6
Parker, N.7
Curtis, K.8
Campbell, M.9
Hu, P.10
Zhang, D.11
Litwin, S.E.12
Zaha, V.G.13
Fountain, K.T.14
Boudina, S.15
Jimenez-Linan, M.16
Blount, M.17
Lopez, M.18
Meirhaeghe, A.19
Bohlooly, Y.M.20
Storlien, L.21
Stromstedt, M.22
Snaith, M.23
Oresic, M.24
Abel, E.D.25
Cannon, B.26
Vidal-Puig, A.27
more..
-
84
-
-
0038036024
-
Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells
-
DOI 10.1074/jbc.M301850200
-
St-Pierre J, Lin J, Krauss S, Tarr PT, Yang R, Newgard CB, Spiegelman BM (2003) Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. J Biol Chem 278:26597-26603 (Pubitemid 36876804)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.29
, pp. 26597-26603
-
-
St-Pierre, J.1
Lin, J.2
Krauss, S.3
Tarr, P.T.4
Yang, R.5
Newgard, C.B.6
Spiegelman, B.M.7
-
85
-
-
33749999530
-
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
-
DOI 10.1016/j.cell.2006.09.024, PII S0092867406012281
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, Jager S, Handschin C, Zheng K, Lin J, Yang W, Simon DK, Bachoo R, Spiegelman BM (2006) Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127:397-408 (Pubitemid 44572377)
-
(2006)
Cell
, vol.127
, Issue.2
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jager, S.6
Handschin, C.7
Zheng, K.8
Lin, J.9
Yang, W.10
Simon, D.K.11
Bachoo, R.12
Spiegelman, B.M.13
-
86
-
-
0042232315
-
PGC-1beta in the regulation of hepatic glucose and energy metabolism
-
DOI 10.1074/jbc.M303643200
-
Lin J, Tarr PT, Yang R, Rhee J, Puigserver P, Newgard CB, Spiegelman BM (2003) PGC-1beta in the regulation of hepatic glucose and energy metabolism. J Biol Chem 278:30843-30848 (Pubitemid 36994593)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.33
, pp. 30843-30848
-
-
Lin, J.1
Tarr, P.T.2
Yang, R.3
Rhee, J.4
Puigserver, P.5
Newgard, C.B.6
Spiegelman, B.M.7
-
87
-
-
78650575544
-
Transcriptional co-activator PGC-1alpha promotes peroxisomal remodeling and biogenesis
-
Bagattin A, Hugendubler L, Mueller E (2010) Transcriptional co-activator PGC-1alpha promotes peroxisomal remodeling and biogenesis. Proc Natl Acad Sci U S A 107:20376-20381
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 20376-20381
-
-
Bagattin, A.1
Hugendubler, L.2
Mueller, E.3
-
88
-
-
0037102256
-
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres
-
Lin J, Wu H, Tarr PT, Zhang CY, Wu Z, Boss O, Michael LF, Puigserver P, Isotani E, Olson EN, Lowell BB, Bassel-Duby R, Spiegelman BM (2002) Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature 418:797-801
-
(2002)
Nature
, vol.418
, pp. 797-801
-
-
Lin, J.1
Wu, H.2
Tarr, P.T.3
Zhang, C.Y.4
Wu, Z.5
Boss, O.6
Michael, L.F.7
Puigserver, P.8
Isotani, E.9
Olson, E.N.10
Lowell, B.B.11
Bassel-Duby, R.12
Spiegelman, B.M.13
-
89
-
-
33845674997
-
The Transcriptional Coactivator PGC-1beta Drives the Formation of Oxidative Type IIX Fibers in Skeletal Muscle
-
DOI 10.1016/j.cmet.2006.12.003, PII S1550413106004001
-
Arany Z, Lebrasseur N, Morris C, Smith E, Yang W, Ma Y, Chin S, Spiegelman BM (2007) The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle. Cell Metab 5:35-46 (Pubitemid 44939399)
-
(2007)
Cell Metabolism
, vol.5
, Issue.1
, pp. 35-46
-
-
Arany, Z.1
Lebrasseur, N.2
Morris, C.3
Smith, E.4
Yang, W.5
Ma, Y.6
Chin, S.7
Spiegelman, B.M.8
-
90
-
-
0036386911
-
Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle
-
Terada S, Goto M, Kato M, Kawanaka K, Shimokawa T, Tabata I (2002) Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle. Biochem Biophys Res Commun 296:350-354
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 350-354
-
-
Terada, S.1
Goto, M.2
Kato, M.3
Kawanaka, K.4
Shimokawa, T.5
Tabata, I.6
-
91
-
-
0034596268
-
cDNA cloning and mRNA analysis of PGC-1 in epitrochlearis muscle in swimming-exercised rats
-
DOI 10.1006/bbrc.2000.3134
-
Goto M, Terada S, Kato M, Katoh M, Yokozeki T, Tabata I, Shimokawa T (2000) cDNA cloning and mRNA analysis of PGC-1 in epitrochlearis muscle in swimming-exercised rats. Biochem Biophys Res Commun 274:350-354 (Pubitemid 30614322)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.274
, Issue.2
, pp. 350-354
-
-
Goto, M.1
Terada, S.2
Kato, M.3
Katoh, M.4
Yokozeki, T.5
Tabata, I.6
Shimokawa, T.7
-
92
-
-
0037322888
-
Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle
-
DOI 10.1113/jphysiol.2002.034850
-
Pilegaard H, Saltin B, Neufer PD (2003) Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle. J Physiol 546:851-858 (Pubitemid 36204518)
-
(2003)
Journal of Physiology
, vol.546
, Issue.3
, pp. 851-858
-
-
Pilegaard, H.1
Saltin, B.2
Neufer, D.P.3
-
93
-
-
33846992686
-
Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1alpha expression
-
DOI 10.1074/jbc.M606116200
-
Wright DC, Han DH, Garcia-Roves PM, Geiger PC, Jones TE, Holloszy JO (2007) Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1alpha expression. J Biol Chem 282:194-199 (Pubitemid 47076618)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.1
, pp. 194-199
-
-
Wright, D.C.1
Han, D.-H.2
Garcia-Roves, P.M.3
Geiger, P.C.4
Jones, T.E.5
Holloszy, J.O.6
-
94
-
-
37549025047
-
A role for the transcriptional coactivator PGC-1alpha in muscle refueling
-
Wende AR, Schaeffer PJ, Parker GJ, Zechner C, Han DH, Chen MM, Hancock CR, Lehman JJ, Huss JM, McClain DA, Holloszy JO, Kelly DP (2007) A role for the transcriptional coactivator PGC-1alpha in muscle refueling. J Biol Chem 282:36642-36651
-
(2007)
J Biol Chem
, vol.282
, pp. 36642-36651
-
-
Wende, A.R.1
Schaeffer, P.J.2
Parker, G.J.3
Zechner, C.4
Han, D.H.5
Chen, M.M.6
Hancock, C.R.7
Lehman, J.J.8
Huss, J.M.9
McClain, D.A.10
Holloszy, J.O.11
Kelly, D.P.12
-
95
-
-
28544438180
-
PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: A mechanism for transcriptional control of muscle glucose metabolism
-
DOI 10.1128/MCB.25.24.10684-10694.2005
-
Wende AR, Huss JM, Schaeffer PJ, Giguere V, Kelly DP (2005) PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism. Mol Cell Biol 25:10684-10694 (Pubitemid 41747115)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.24
, pp. 10684-10694
-
-
Wende, A.R.1
Huss, J.M.2
Schaeffer, P.J.3
Giguere, V.4
Kelly, D.P.5
-
96
-
-
45149108625
-
Muscle-specific expression of PPARgamma coactivator-1alpha improves exercise performance and increases peak oxygen uptake
-
Calvo JA, Daniels TG, Wang X, Paul A, Lin J, Spiegelman BM, Stevenson SC, Rangwala SM (2008) Muscle-specific expression of PPARgamma coactivator-1alpha improves exercise performance and increases peak oxygen uptake. J Appl Physiol 104:1304-1312
-
(2008)
J Appl Physiol
, vol.104
, pp. 1304-1312
-
-
Calvo, J.A.1
Daniels, T.G.2
Wang, X.3
Paul, A.4
Lin, J.5
Spiegelman, B.M.6
Stevenson, S.C.7
Rangwala, S.M.8
-
97
-
-
77958453583
-
Peroxisome proliferator-activated receptor gamma coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway
-
Summermatter S, Baum O, Santos G, Hoppeler H, Handschin C (2010) Peroxisome proliferator-activated receptor gamma coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway. J Biol Chem 285:32793-32800
-
(2010)
J Biol Chem
, vol.285
, pp. 32793-32800
-
-
Summermatter, S.1
Baum, O.2
Santos, G.3
Hoppeler, H.4
Handschin, C.5
-
98
-
-
79955410387
-
Coordinated balancing of muscle oxidative metabolism through PGC-1alpha increases metabolic flexibility and preserves insulin sensitivity
-
Summermatter S, Troxler H, Santos G, Handschin C (2011) Coordinated balancing of muscle oxidative metabolism through PGC-1alpha increases metabolic flexibility and preserves insulin sensitivity. Biochem Biophys Res Commun 408:180-185
-
(2011)
Biochem Biophys Res Commun
, vol.408
, pp. 180-185
-
-
Summermatter, S.1
Troxler, H.2
Santos, G.3
Handschin, C.4
-
99
-
-
33748313028
-
The contraction induced increase in gene expression of peroxisome proliferator-activated receptor (PPAR)-gamma coactivator 1alpha (PGC-1alpha), mitochondrial uncoupling protein 3 (UCP3) and hexokinase II (HKII) in primary rat skeletal muscle cells is dependent on reactive oxygen species
-
DOI 10.1016/j.bbamcr.2006.06.010, PII S0167488906001467
-
Silveira LR, Pilegaard H, Kusuhara K, Curi R, Hellsten Y (2006) The contraction induced increase in gene expression of peroxisome proliferator-activated receptor (PPAR)-gamma coactivator 1alpha (PGC-1alpha), mitochondrial uncoupling protein 3 (UCP3) and hexokinase II (HKII) in primary rat skeletal muscle cells is dependent on reactive oxygen species. Biochim Biophys Acta 1763:969-976 (Pubitemid 44332599)
-
(2006)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1763
, Issue.9
, pp. 969-976
-
-
Silveira, L.R.1
Pilegaard, H.2
Kusuhara, K.3
Curi, R.4
Hellsten, Y.5
-
100
-
-
73949099327
-
Increased muscle PGC-1alpha expression protects from sarcopenia and metabolic disease during aging
-
Wenz T, Rossi SG, Rotundo RL, Spiegelman BM, Moraes CT (2009) Increased muscle PGC-1alpha expression protects from sarcopenia and metabolic disease during aging. Proc Natl Acad Sci U S A 106:20405-20410
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 20405-20410
-
-
Wenz, T.1
Rossi, S.G.2
Rotundo, R.L.3
Spiegelman, B.M.4
Moraes, C.T.5
-
101
-
-
34147109662
-
PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy
-
DOI 10.1101/gad.1525107
-
Handschin C, Kobayashi YM, Chin S, Seale P, Campbell KP, Spiegelman BM (2007) PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy. Genes Dev 21:770-783 (Pubitemid 46572357)
-
(2007)
Genes and Development
, vol.21
, Issue.7
, pp. 770-783
-
-
Handschin, C.1
Kobayashi, Y.M.2
Chin, S.3
Seale, P.4
Campbell, K.P.5
Spiegelman, B.M.6
-
102
-
-
83455223600
-
Remodeling of calcium handling in skeletal muscle through PGC-1alpha: Impact on force, fatigability, and fiber type
-
Summermatter S, Thurnheer R, Santos G, Mosca B, Baum O, Treves S, Hoppeler H, Zorzato F, Handschin C (2012) Remodeling of calcium handling in skeletal muscle through PGC-1alpha: impact on force, fatigability, and fiber type. Am J Physiol Cell Physiol 302:C88-C99
-
(2012)
Am J Physiol Cell Physiol
, vol.302
-
-
Summermatter, S.1
Thurnheer, R.2
Santos, G.3
Mosca, B.4
Baum, O.5
Treves, S.6
Hoppeler, H.7
Zorzato, F.8
Handschin, C.9
-
103
-
-
39749140405
-
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha
-
DOI 10.1038/nature06613, PII NATURE06613
-
Arany Z, Foo SY, Ma Y, Ruas JL, Bommi-Reddy A, Girnun G, Cooper M, Laznik D, Chinsomboon J, Rangwala SM, Baek KH, Rosenzweig A, Spiegelman BM (2008) HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha. Nature 451:1008-1012 (Pubitemid 351301733)
-
(2008)
Nature
, vol.451
, Issue.7181
, pp. 1008-1012
-
-
Arany, Z.1
Foo, S.-Y.2
Ma, Y.3
Ruas, J.L.4
Bommi-Reddy, A.5
Girnun, G.6
Cooper, M.7
Laznik, D.8
Chinsomboon, J.9
Rangwala, S.M.10
Baek, K.H.11
Rosenzweig, A.12
Spiegelman, B.M.13
-
104
-
-
75849155745
-
The transcriptional coactivator PGC-1alphamediates exercise-induced angiogenesis in skeletal muscle
-
Chinsomboon J, Ruas J, Gupta RK, Thom R, Shoag J, Rowe GC, Sawada N, Raghuram S, Arany Z (2009) The transcriptional coactivator PGC-1alphamediates exercise-induced angiogenesis in skeletal muscle. Proc Natl Acad Sci U S A 106:21401-21406
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 21401-21406
-
-
Chinsomboon, J.1
Ruas, J.2
Gupta, R.K.3
Thom, R.4
Shoag, J.5
Rowe, G.C.6
Sawada, N.7
Raghuram, S.8
Arany, Z.9
-
105
-
-
35648937073
-
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals
-
DOI 10.1074/jbc.M704817200
-
Handschin C, Chin S, Li P, Liu F, Maratos-Flier E, Lebrasseur NK, Yan Z, Spiegelman BM (2007) Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals. J Biol Chem 282:30014-30021 (Pubitemid 350035265)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.41
, pp. 30014-30021
-
-
Handschin, C.1
Chin, S.2
Li, P.3
Liu, F.4
Maratos-Flier, E.5
LeBrasseur, N.K.6
Yan, Z.7
Spiegelman, B.M.8
-
106
-
-
78649508058
-
Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity
-
Zechner C, Lai L, Zechner JF, Geng T, Yan Z, Rumsey JW, Collia D, Chen Z, Wozniak DF, Leone TC, Kelly DP (2011) Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity. Cell Metab 12:633-642
-
(2011)
Cell Metab
, vol.12
, pp. 633-642
-
-
Zechner, C.1
Lai, L.2
Zechner, J.F.3
Geng, T.4
Yan, Z.5
Rumsey, J.W.6
Collia, D.7
Chen, Z.8
Wozniak, D.F.9
Leone, T.C.10
Kelly, D.P.11
-
108
-
-
33646819995
-
Myogenic basic helix-loop-helix proteins regulate the expression of peroxisomal proliferator activated receptor-gamma coactivator-1alpha
-
Chang JH, Lin KH, Shih CH, Chang YJ, Chi HC, Chen SL (2006) Myogenic basic helix-loop-helix proteins regulate the expression of peroxisomal proliferator activated receptor-gamma coactivator-1alpha. Endocrinology 147:3093-3106
-
(2006)
Endocrinology
, vol.147
, pp. 3093-3106
-
-
Chang, J.H.1
Lin, K.H.2
Shih, C.H.3
Chang, Y.J.4
Chi, H.C.5
Chen, S.L.6
-
109
-
-
34249275727
-
Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism
-
DOI 10.1038/nature05767, PII NATURE05767
-
Liu C, Li S, Liu T, Borjigin J, Lin JD (2007) Transcriptional coactivator PGC-1alpha integrates themammalian clock and energy metabolism. Nature 447:477-481 (Pubitemid 46816732)
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 477-481
-
-
Liu, C.1
Li, S.2
Liu, T.3
Borjigin, J.4
Lin, J.D.5
-
110
-
-
78650501389
-
CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function
-
Andrews JL, Zhang X, McCarthy JJ, McDearmon EL, Hornberger TA, Russell B, Campbell KS, Arbogast S, Reid MB, Walker JR, Hogenesch JB, Takahashi JS, Esser KA (2010) CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function. Proc Natl Acad Sci U S A 107:19090-19095
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 19090-19095
-
-
Andrews, J.L.1
Zhang, X.2
McCarthy, J.J.3
McDearmon, E.L.4
Hornberger, T.A.5
Russell, B.6
Campbell, K.S.7
Arbogast, S.8
Reid, M.B.9
Walker, J.R.10
Hogenesch, J.B.11
Takahashi, J.S.12
Esser, K.A.13
-
111
-
-
58149395124
-
Selenoprotein P expression is controlled through interaction of the coactivator PGC-1alpha with FoxO1a and hepatocyte nuclear factor 4alpha transcription factors
-
Speckmann B, Walter PL, Alili L, Reinehr R, Sies H, Klotz LO, Steinbrenner H (2008) Selenoprotein P expression is controlled through interaction of the coactivator PGC-1alpha with FoxO1a and hepatocyte nuclear factor 4alpha transcription factors. Hepatol 48:1998-2006
-
(2008)
Hepatol
, vol.48
, pp. 1998-2006
-
-
Speckmann, B.1
Walter, P.L.2
Alili, L.3
Reinehr, R.4
Sies, H.5
Klotz, L.O.6
Steinbrenner, H.7
-
112
-
-
23944476164
-
Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha
-
DOI 10.1016/j.cell.2005.06.040, PII S0092867405006604
-
Handschin C, Lin J, Rhee J, Peyer AK, Chin S, Wu PH, Meyer UA, Spiegelman BM (2005) Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha. Cell 122:505-515 (Pubitemid 41191150)
-
(2005)
Cell
, vol.122
, Issue.4
, pp. 505-515
-
-
Handschin, C.1
Lin, J.2
Rhee, J.3
Peyer, A.-K.4
Chin, S.5
Wu, P.-H.6
Meyer, U.A.7
Spiegelman, B.M.8
-
113
-
-
0346118926
-
PGC-1alpha Activates CYP7A1 and Bile Acid Biosynthesis
-
DOI 10.1074/jbc.M309736200
-
Shin DJ, Campos JA, Gil G, Osborne TF (2003) PGC-1alpha activates CYP7A1 and bile acid biosynthesis. J Biol Chem 278:50047-50052 (Pubitemid 37548841)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.50
, pp. 50047-50052
-
-
Shin, D.-J.1
Campos, J.A.2
Gil, G.3
Osborne, T.F.4
-
114
-
-
64749096339
-
Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1alpha
-
Li S, Arning E, Liu C, Vitvitsky V, Hernandez C, Banerjee R, Bottiglieri T, Lin JD (2009) Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1alpha. Am J Physiol Endocrinol Metab 296:E543-E548
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
-
-
Li, S.1
Arning, E.2
Liu, C.3
Vitvitsky, V.4
Hernandez, C.5
Banerjee, R.6
Bottiglieri, T.7
Lin, J.D.8
-
115
-
-
22144434964
-
Transcriptional coactivator PGC-1alpha controls the energy state and contractile function of cardiac muscle
-
DOI 10.1016/j.cmet.2005.03.002, PII S1550413105000811
-
Arany Z, He H, Lin J, Hoyer K, Handschin C, Toka O, Ahmad F, Matsui T, Chin S, Wu PH, Rybkin II, Shelton JM, Manieri M, Cinti S, Schoen FJ, Bassel-Duby R, Rosenzweig A, Ingwall JS, Spiegelman BM (2005) Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle. Cell Metab 1:259-271 (Pubitemid 43960608)
-
(2005)
Cell Metabolism
, vol.1
, Issue.4
, pp. 259-271
-
-
Arany, Z.1
He, H.2
Lin, J.3
Hoyer, K.4
Handschin, C.5
Toka, O.6
Ahmad, F.7
Matsui, T.8
Chin, S.9
Wu, P.-H.10
Rybkin, I.I.11
Shelton, J.M.12
Manieri, M.13
Cinti, S.14
Schoen, F.J.15
Bassel-Duby, R.16
Rosenzweig, A.17
Ingwall, J.S.18
Spiegelman, B.M.19
-
116
-
-
33745627066
-
Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha
-
DOI 10.1073/pnas.0603615103
-
Arany Z, Novikov M, Chin S, Ma Y, Rosenzweig A, Spiegelman BM (2006) Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha. Proc Natl Acad Sci U S A 103:10086-10091 (Pubitemid 43993627)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.26
, pp. 10086-10091
-
-
Arany, Z.1
Novikov, M.2
Chin, S.3
Ma, Y.4
Rosenzweig, A.5
Spiegelman, B.M.6
-
117
-
-
80052970004
-
PGC-1beta deficiency accelerates the transition to heart failure in pressure overload hypertrophy
-
Riehle C, Wende AR, Zaha VG, Pires KM, Wayment B, Olsen C, Bugger H, Buchanan J, Wang X, Moreira AB, Doenst T, Medina-Gomez G, Litwin SE, Lelliott CJ, Vidal-Puig A, Abel ED (2011) PGC-1beta deficiency accelerates the transition to heart failure in pressure overload hypertrophy. Circ Res 109:783-793
-
(2011)
Circ Res
, vol.109
, pp. 783-793
-
-
Riehle, C.1
Wende, A.R.2
Zaha, V.G.3
Pires, K.M.4
Wayment, B.5
Olsen, C.6
Bugger, H.7
Buchanan, J.8
Wang, X.9
Moreira, A.B.10
Doenst, T.11
Medina-Gomez, G.12
Litwin, S.E.13
Lelliott, C.J.14
Vidal-Puig, A.15
Abel, E.D.16
-
118
-
-
47549114849
-
Transcriptional coactivators PGC-lalpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart
-
DOI 10.1101/gad.1661708
-
Lai L, Leone TC, Zechner C, Schaeffer PJ, Kelly SM, Flanagan DP, Medeiros DM, Kovacs A, Kelly DP (2008) Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart. Genes Dev 22:1948-1961 (Pubitemid 352008642)
-
(2008)
Genes and Development
, vol.22
, Issue.14
, pp. 1948-1961
-
-
Lai, L.1
Leone, T.C.2
Zechner, C.3
Schaeffer, P.J.4
Kelly, S.M.5
Flanagan, D.P.6
Medeiros, D.M.7
Kovacs, A.8
Kelly, D.P.9
-
119
-
-
0033803048
-
Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis
-
Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP (2000) Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest 106:847-856
-
(2000)
J Clin Invest
, vol.106
, pp. 847-856
-
-
Lehman, J.J.1
Barger, P.M.2
Kovacs, A.3
Saffitz, J.E.4
Medeiros, D.M.5
Kelly, D.P.6
-
120
-
-
33646124709
-
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
-
Uldry M, Yang W, St-Pierre J, Lin J, Seale P, Spiegelman BM (2006) Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metab 3:333-341
-
(2006)
Cell Metab
, vol.3
, pp. 333-341
-
-
Uldry, M.1
Yang, W.2
St-Pierre, J.3
Lin, J.4
Seale, P.5
Spiegelman, B.M.6
-
121
-
-
44149113548
-
Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex
-
DOI 10.1101/gad.1666108
-
Kajimura S, Seale P, Tomaru T, Erdjument-Bromage H, Cooper MP, Ruas JL, Chin S, Tempst P, Lazar MA, Spiegelman BM (2008) Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes Dev 22:1397-1409 (Pubitemid 351717529)
-
(2008)
Genes and Development
, vol.22
, Issue.10
, pp. 1397-1409
-
-
Kajimura, S.1
Seale, P.2
Tomaru, T.3
Erdjument-Bromage, H.4
Cooper, M.P.5
Ruas, J.L.6
Chin, S.7
Tempst, P.8
Lazar, M.A.9
Spiegelman, B.M.10
-
122
-
-
82955187865
-
Skeletal muscle-specific expression of PGC-1alpha-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake
-
Tadaishi M, Miura S, Kai Y, Kano Y, Oishi Y, Ezaki O (2011) Skeletal muscle-specific expression of PGC-1alpha-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake. PLoS One 6:e28290
-
(2011)
PLoS One
, vol.6
-
-
Tadaishi, M.1
Miura, S.2
Kai, Y.3
Kano, Y.4
Oishi, Y.5
Ezaki, O.6
-
123
-
-
84863012022
-
FGF21 regulates PGC-1alpha and browning of white adipose tissues in adaptive thermogenesis
-
Fisher FM, Kleiner S, Douris N, Fox EC, Mepani RJ, Verdeguer F, Wu J, Kharitonenkov A, Flier JS, Maratos-Flier E, Spiegelman BM (2012) FGF21 regulates PGC-1alpha and browning of white adipose tissues in adaptive thermogenesis. Genes Dev 26:271-281
-
(2012)
Genes Dev
, vol.26
, pp. 271-281
-
-
Fisher, F.M.1
Kleiner, S.2
Douris, N.3
Fox, E.C.4
Mepani, R.J.5
Verdeguer, F.6
Wu, J.7
Kharitonenkov, A.8
Flier, J.S.9
Maratos-Flier, E.10
Spiegelman, B.M.11
-
124
-
-
33645064540
-
Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1alpha
-
Scime A, Grenier G, Huh MS, Gillespie MA, Bevilacqua L, Harper ME, Rudnicki MA (2005) Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1alpha. Cell Metab 2:283-295
-
(2005)
Cell Metab
, vol.2
, pp. 283-295
-
-
Scime, A.1
Grenier, G.2
Huh, M.S.3
Gillespie, M.A.4
Bevilacqua, L.5
Harper, M.E.6
Rudnicki, M.A.7
-
125
-
-
63049083171
-
Twist-1 is a PPARdelta-inducible, negative-feedback regulator of PGC-1alpha in brown fat metabolism
-
Pan D, Fujimoto M, Lopes A, Wang YX (2009) Twist-1 is a PPARdelta-inducible, negative-feedback regulator of PGC-1alpha in brown fat metabolism. Cell 137:73-86
-
(2009)
Cell
, vol.137
, pp. 73-86
-
-
Pan, D.1
Fujimoto, M.2
Lopes, A.3
Wang, Y.X.4
-
126
-
-
84862162100
-
Development of insulin resistance in mice lacking PGC-1alpha in adipose tissues
-
Kleiner S, Mepani RJ, Laznik D, Ye L, Jurczak MJ, Jornayvaz FR, Estall JL, Chatterjee Bhowmick D, Shulman GI, Spiegelman BM (2012) Development of insulin resistance in mice lacking PGC-1alpha in adipose tissues. Proc Natl Acad Sci U S A 109:9635-9640
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 9635-9640
-
-
Kleiner, S.1
Mepani, R.J.2
Laznik, D.3
Ye, L.4
Jurczak, M.J.5
Jornayvaz, F.R.6
Estall, J.L.7
Chatterjee Bhowmick, D.8
Shulman, G.I.9
Spiegelman, B.M.10
-
127
-
-
0038686576
-
Suppression of beta cell energy metabolism and insulin release by PGC-1alpha
-
DOI 10.1016/S1534-5807(03)00170-9, PII S1534580703001709
-
Yoon JC, Xu G, Deeney JT, Yang SN, Rhee J, Puigserver P, Levens AR, Yang R, Zhang CY, Lowell BB, Berggren PO, Newgard CB, Bonner-Weir S, Weir G, Spiegelman BM (2003) Suppression of beta cell energy metabolism and insulin release by PGC-1alpha. Dev Cell 5:73-83 (Pubitemid 36827343)
-
(2003)
Developmental Cell
, vol.5
, Issue.1
, pp. 73-83
-
-
Yoon, J.C.1
Xu, G.2
Deeney, J.T.3
Yang, S.-N.4
Rhee, J.5
Puigserver, P.6
Levens, A.R.7
Yang, R.8
Zhang, C.-Y.9
Lowell, B.B.10
Berggren, P.-O.11
Newgard, C.B.12
Bonner-Weir, S.13
Weir, G.14
Spiegelman, B.M.15
-
128
-
-
41149172495
-
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion
-
Ling C, Del Guerra S, Lupi R, Ronn T, Granhall C, Luthman H, Masiello P, Marchetti P, Groop L, Del Prato S (2008) Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion. Diabetologia 51:615-622
-
(2008)
Diabetologia
, vol.51
, pp. 615-622
-
-
Ling, C.1
Del Guerra, S.2
Lupi, R.3
Ronn, T.4
Granhall, C.5
Luthman, H.6
Masiello, P.7
Marchetti, P.8
Groop, L.9
Del Prato, S.10
-
129
-
-
69249084890
-
PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons
-
Wareski P, Vaarmann A, Choubey V, Safiulina D, Liiv J, Kuum M, Kaasik A (2009) PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons. J Biol Chem 284:21379-21385
-
(2009)
J Biol Chem
, vol.284
, pp. 21379-21385
-
-
Wareski, P.1
Vaarmann, A.2
Choubey, V.3
Safiulina, D.4
Liiv, J.5
Kuum, M.6
Kaasik, A.7
-
130
-
-
81555206662
-
PGC-1alpha protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model
-
Liang H, Ward WF, Jang YC, Bhattacharya A, Bokov AF, Li Y, Jernigan A, Richardson A, Van Remmen H (2011) PGC-1alpha protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model. Muscle Nerve 44:947-956
-
(2011)
Muscle Nerve
, vol.44
, pp. 947-956
-
-
Liang, H.1
Ward, W.F.2
Jang, Y.C.3
Bhattacharya, A.4
Bokov, A.F.5
Li, Y.6
Jernigan, A.7
Richardson, A.8
Van Remmen, H.9
-
131
-
-
33749042331
-
Transcriptional Repression of PGC-1alpha by Mutant Huntingtin Leads to Mitochondrial Dysfunction and Neurodegeneration
-
DOI 10.1016/j.cell.2006.09.015, PII S0092867406012050
-
Cui L, Jeong H, Borovecki F, Parkhurst CN, Tanese N, Krainc D (2006) Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 127:59-69 (Pubitemid 44466642)
-
(2006)
Cell
, vol.127
, Issue.1
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
Parkhurst, C.N.4
Tanese, N.5
Krainc, D.6
-
132
-
-
62449166389
-
PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia
-
Qin W, Haroutunian V, Katsel P, Cardozo CP, Ho L, Buxbaum JD, Pasinetti GM (2009) PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia. Arch Neurol 66:352-361
-
(2009)
Arch Neurol
, vol.66
, pp. 352-361
-
-
Qin, W.1
Haroutunian, V.2
Katsel, P.3
Cardozo, C.P.4
Ho, L.5
Buxbaum, J.D.6
Pasinetti, G.M.7
-
133
-
-
78649819597
-
Neuronal inactivation of peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) protects mice from diet-induced obesity and leads to degenerative lesions
-
Ma D, Li S, Lucas EK, Cowell RM, Lin JD (2010) Neuronal inactivation of peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) protects mice from diet-induced obesity and leads to degenerative lesions. J Biol Chem 285:39087-39095
-
(2010)
J Biol Chem
, vol.285
, pp. 39087-39095
-
-
Ma, D.1
Li, S.2
Lucas, E.K.3
Cowell, R.M.4
Lin, J.D.5
-
134
-
-
84856905436
-
PGC-1alpha determines light damage susceptibility of the murine retina
-
Egger A, Samardzija M, Sothilingam V, Tanimoto N, Lange C, Salatino S, Fang L, Garcia-Garrido M, Beck S, Okoniewski MJ, Neutzner A, Seeliger MW, Grimm C, Handschin C (2012) PGC-1alpha determines light damage susceptibility of the murine retina. PLoS One 7:e31272
-
(2012)
PLoS One
, vol.7
-
-
Egger, A.1
Samardzija, M.2
Sothilingam, V.3
Tanimoto, N.4
Lange, C.5
Salatino, S.6
Fang, L.7
Garcia-Garrido, M.8
Beck, S.9
Okoniewski, M.J.10
Neutzner, A.11
Seeliger, M.W.12
Grimm, C.13
Handschin, C.14
-
135
-
-
20044369930
-
Transcriptional coactivator PGC-1alpha regulates chondrogenesis via association with Sox9
-
DOI 10.1073/pnas.0407510102
-
Kawakami Y, Tsuda M, Takahashi S, Taniguchi N, Esteban CR, Zemmyo M, Furumatsu T, Lotz M, Belmonte JC, Asahara H (2005) Transcriptional coactivator PGC-1alpha regulates chondrogenesis via association with Sox9. Proc Natl Acad Sci U S A 102:2414-2419 (Pubitemid 40279390)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.7
, pp. 2414-2419
-
-
Kawakami, Y.1
Tsuda, M.2
Takahashi, S.3
Taniguchi, N.4
Esteban, C.R.5
Zemmyo, M.6
Furumatsu, T.7
Lotz, M.8
Belmonte, J.C.I.9
Asahara, H.10
-
136
-
-
62049085382
-
Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation
-
Ishii KA, Fumoto T, Iwai K, Takeshita S, Ito M, Shimohata N, Aburatani H, Taketani S, Lelliott CJ, Vidal-Puig A, Ikeda K (2009) Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation. Nat Med 15:259-266
-
(2009)
Nat Med
, vol.15
, pp. 259-266
-
-
Ishii, K.A.1
Fumoto, T.2
Iwai, K.3
Takeshita, S.4
Ito, M.5
Shimohata, N.6
Aburatani, H.7
Taketani, S.8
Lelliott, C.J.9
Vidal-Puig, A.10
Ikeda, K.11
-
137
-
-
33749630419
-
PGC-1-related coactivator: Immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth
-
DOI 10.1128/MCB.00585-06
-
Vercauteren K, Pasko RA, Gleyzer N, Marino VM, Scarpulla RC (2006) PGC-1-related coactivator: immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth. Mol Cell Biol 26:7409-7419 (Pubitemid 44547693)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.20
, pp. 7409-7419
-
-
Vercauteren, K.1
Pasko, R.A.2
Gleyzer, N.3
Marino, V.M.4
Scarpulla, R.C.5
-
138
-
-
33846015010
-
Rapid disuse and denervation atrophy involve transcriptional changes similar to those of muscle wasting during systemic diseases
-
DOI 10.1096/fj.06-6604com
-
Sacheck JM, Hyatt JP, Raffaello A, Jagoe RT, Roy RR, Edgerton VR, Lecker SH, Goldberg AL (2007) Rapid disuse and denervation atrophy involve transcriptional changes similar to those of muscle wasting during systemic diseases. FASEB J 21:140-155 (Pubitemid 46052553)
-
(2007)
FASEB Journal
, vol.21
, Issue.1
, pp. 140-155
-
-
Sacheck, J.M.1
Hyatt, J.-P.K.2
Raffaello, A.3
Jagoe, R.T.4
Roy, R.R.5
Edgerton, V.R.6
Lecker, S.H.7
Goldberg, A.L.8
-
139
-
-
33847730262
-
Effect of denervation on mitochondrially mediated apoptosis in skeletal muscle
-
DOI 10.1152/japplphysiol.00768.2006
-
Adhihetty PJ, O'Leary MF, Chabi B, Wicks KL, Hood DA (2007) Effect of denervation on mitochondrially mediated apoptosis in skeletal muscle. J Appl Physiol 102:1143-1151 (Pubitemid 46377042)
-
(2007)
Journal of Applied Physiology
, vol.102
, Issue.3
, pp. 1143-1151
-
-
Adhihetty, P.J.1
O'Leary, M.F.N.2
Chabi, B.3
Wicks, K.L.4
Hood, D.A.5
-
140
-
-
33750825245
-
PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription
-
DOI 10.1073/pnas.0607795103
-
Sandri M, Lin J, Handschin C, Yang W, Arany ZP, Lecker SH, Goldberg AL, Spiegelman BM(2006) PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription. Proc Natl Acad Sci U S A 103:16260-16265 (Pubitemid 44715184)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.44
, pp. 16260-16265
-
-
Sandri, M.1
Lin, J.2
Handschin, C.3
Yang, W.4
Arany, Z.P.5
Lecker, S.H.6
Goldberg, A.L.7
Spiegelman, B.M.8
-
141
-
-
36849045916
-
The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity
-
DOI 10.1172/JCI32741.
-
Hanai J, Cao P, Tanksale P, Imamura S, Koshimizu E, Zhao J, Kishi S, Yamashita M, Phillips PS, Sukhatme VP, Lecker SH (2007) The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity. J Clin Invest 117:3940-3951 (Pubitemid 350224103)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.12
, pp. 3940-3951
-
-
Hanai, J.-I.1
Cao, P.2
Tanksale, P.3
Imamura, S.4
Koshimizu, E.5
Zhao, J.6
Kishi, S.7
Yamashita, M.8
Phillips, P.S.9
Sukhatme, V.P.10
Lecker, S.H.11
-
142
-
-
77953495952
-
Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy
-
Brault JJ, Jespersen JG, Goldberg AL (2010) Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy. J Biol Chem 285:19460-19471
-
(2010)
J Biol Chem
, vol.285
, pp. 19460-19471
-
-
Brault, J.J.1
Jespersen, J.G.2
Goldberg, A.L.3
-
143
-
-
50049118173
-
Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype
-
Wenz T, Diaz F, Spiegelman BM, Moraes CT (2008) Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype. Cell Metab 8:249-256
-
(2008)
Cell Metab
, vol.8
, pp. 249-256
-
-
Wenz, T.1
Diaz, F.2
Spiegelman, B.M.3
Moraes, C.T.4
-
144
-
-
66349120223
-
Endurance exercise is protective for mice with mitochondrial myopathy
-
Wenz T, Diaz F, Hernandez D, Moraes CT (2009) Endurance exercise is protective for mice with mitochondrial myopathy. J Appl Physiol 106:1712-1719
-
(2009)
J Appl Physiol
, vol.106
, pp. 1712-1719
-
-
Wenz, T.1
Diaz, F.2
Hernandez, D.3
Moraes, C.T.4
-
145
-
-
67650061723
-
Impaired PGC-1alpha function in muscle in Huntington's disease
-
Chaturvedi RK, Adhihetty P, Shukla S, Hennessy T, Calingasan N, Yang L, Starkov A, Kiaei M, Cannella M, Sassone J, Ciammola A, Squitieri F, Beal MF (2009) Impaired PGC-1alpha function in muscle in Huntington's disease. Hum Mol Genet 18:3048-3065
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3048-3065
-
-
Chaturvedi, R.K.1
Adhihetty, P.2
Shukla, S.3
Hennessy, T.4
Calingasan, N.5
Yang, L.6
Starkov, A.7
Kiaei, M.8
Cannella, M.9
Sassone, J.10
Ciammola, A.11
Squitieri, F.12
Beal, M.F.13
-
146
-
-
34447511610
-
Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: Potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation
-
DOI 10.1074/jbc.M611214200
-
Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, Espinoza D, Faucette R, Barry K, Bianco AC, Patti ME (2007) Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. J Biol Chem 282:15439-15450 (Pubitemid 47093279)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.21
, pp. 15439-15450
-
-
Crunkhorn, S.1
Dearie, F.2
Mantzoros, C.3
Gami, H.4
Da, S.W.S.5
Espinoza, D.6
Faucette, R.7
Barry, K.8
Bianco, A.C.9
Patti, M.E.10
-
147
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
DOI 10.1038/ng1180
-
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstrale M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman BM, Lander ES, Hirschhorn JN, Altshuler D, Groop LC (2003) PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34:267-273 (Pubitemid 36792858)
-
(2003)
Nature Genetics
, vol.34
, Issue.3
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.-F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstrale, M.9
Laurila, E.10
Houstis, N.11
Daly, M.J.12
Patterson, N.13
Mesirov, J.P.14
Golub, T.R.15
Tamayo, P.16
Spiegelman, B.17
Lander, E.S.18
Hirschhorn, J.N.19
Altshuler, D.20
Groop, L.C.21
more..
-
148
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
DOI 10.1073/pnas.1032913100
-
Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, Kahn CR, Mandarino LJ (2003) Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc Natl Acad Sci U S A 100:8466-8471 (Pubitemid 36842568)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.14
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
Cusi, K.4
Berria, R.5
Kashyap, S.6
Miyazaki, Y.7
Kohane, I.8
Costello, M.9
Saccone, R.10
Landaker, E.J.11
Goldfine, A.B.12
Mun, E.13
DeFronzo, R.14
Finlayson, J.15
Kahn, C.R.16
Mandarino, L.J.17
-
149
-
-
31044433308
-
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents
-
DOI 10.1172/JCI25151
-
Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI (2005) Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents. J Clin Invest 115:3587-3593 (Pubitemid 43121847)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.12
, pp. 3587-3593
-
-
Morino, K.1
Petersen, K.F.2
Dufour, S.3
Befroy, D.4
Frattini, J.5
Shatzkes, N.6
Neschen, S.7
White, M.F.8
Bilz, S.9
Sono, S.10
Pypaert, M.11
Shulman, G.I.12
-
150
-
-
42949083922
-
Modest PGC-1alpha overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria
-
Benton CR, Nickerson JG, Lally J, Han XX, Holloway GP, Glatz JF, Luiken JJ, Graham TE, Heikkila JJ, Bonen A (2008) Modest PGC-1alpha overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria. J Biol Chem 283:4228-4240
-
(2008)
J Biol Chem
, vol.283
, pp. 4228-4240
-
-
Benton, C.R.1
Nickerson, J.G.2
Lally, J.3
Han, X.X.4
Holloway, G.P.5
Glatz, J.F.6
Luiken, J.J.7
Graham, T.E.8
Heikkila, J.J.9
Bonen, A.10
-
151
-
-
36048931015
-
Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk
-
DOI 10.1172/JCI31785
-
Handschin C, Choi CS, Chin S, Kim S, Kawamori D, Kurpad AJ, Neubauer N, Hu J, Mootha VK, Kim YB, Kulkarni RN, Shulman GI, Spiegelman BM(2007) Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk. J Clin Invest 117:3463-3474 (Pubitemid 350097002)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.11
, pp. 3463-3474
-
-
Handschin, C.1
Cheol, S.C.2
Chin, S.3
Kim, S.4
Kawamori, D.5
Kurpad, A.J.6
Neubauer, N.7
Hu, J.8
Mootha, V.K.9
Kim, Y.-B.10
Kulkarni, R.N.11
Shulman, G.I.12
Spiegelman, B.M.13
-
152
-
-
58149401189
-
Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism
-
Choi CS, Befroy DE, Codella R, Kim S, Reznick RM, Hwang YJ, Liu ZX, Lee HY, Distefano A, Samuel VT, Zhang D, Cline GW, Handschin C, Lin J, Petersen KF, Spiegelman BM, Shulman GI (2008) Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism. Proc Natl Acad Sci U S A 105:19926-19931
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19926-19931
-
-
Choi, C.S.1
Befroy, D.E.2
Codella, R.3
Kim, S.4
Reznick, R.M.5
Hwang, Y.J.6
Liu, Z.X.7
Lee, H.Y.8
Distefano, A.9
Samuel, V.T.10
Zhang, D.11
Cline, G.W.12
Handschin, C.13
Lin, J.14
Petersen, K.F.15
Spiegelman, B.M.16
Shulman, G.I.17
-
153
-
-
85047691371
-
Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins
-
DOI 10.1172/JCI200421889
-
Ling C, Poulsen P, Carlsson E, Ridderstrale M, Almgren P, Wojtaszewski J, Beck-Nielsen H, Groop L, Vaag A (2004) Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins. J Clin Invest 114:1518-1526 (Pubitemid 40385582)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.10
, pp. 1518-1526
-
-
Ling, C.1
Poulsen, P.2
Carlsson, E.3
Ridderstrale, M.4
Almgren, P.5
Wojtaszewski, J.6
Beck-Nielsen, H.7
Groop, L.8
Vaag, A.9
-
154
-
-
0035676129
-
Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus
-
DOI 10.1007/s001250100032
-
Ek J, Andersen G, Urhammer SA, Gaede PH, Drivsholm T, Borch-Johnsen K, Hansen T, Pedersen O (2001) Mutation analysis of peroxisome proliferator- activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus. Diabetologia 44:2220-2226 (Pubitemid 34015475)
-
(2001)
Diabetologia
, vol.44
, Issue.12
, pp. 2220-2226
-
-
Ek, J.1
Andersen, G.2
Urhammer, S.A.3
Gaede, P.H.4
Drivsholm, T.5
Borch-Johnsen, K.6
Hansen, T.7
Pedersen, O.8
-
155
-
-
0036094896
-
No association between the G482S polymorphism of the proliferator- activated receptor- gamma coactivator-1 (PGC-1) gene and type II diabetes in French Caucasians
-
discussion 4
-
Lacquemant C, Chikri M, Boutin P, Samson C, Froguel P (2002) No association between the G482S polymorphism of the proliferator-activated receptor- gamma coactivator-1 (PGC-1) gene and type II diabetes in French Caucasians. Diabetologia 45:602-603, discussion 4
-
(2002)
Diabetologia
, vol.45
, pp. 602-603
-
-
Lacquemant, C.1
Chikri, M.2
Boutin, P.3
Samson, C.4
Froguel, P.5
-
156
-
-
33845770418
-
Analysis of PGC-1alpha variants Gly482Ser and Thr612Met concerning their PPARgamma2-coactivation function
-
DOI 10.1016/j.bbrc.2006.12.042, PII S0006291X06027045
-
Nitz I, Ewert A, Klapper M, Doring F (2007) Analysis of PGC-1alpha variants Gly482Ser and Thr612Met concerning their PPARgamma2-coactivation function. Biochem Biophys Res Commun 353:481-486 (Pubitemid 46014589)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.353
, Issue.2
, pp. 481-486
-
-
Nitz, I.1
Ewert, A.2
Klapper, M.3
Doring, F.4
-
157
-
-
23944504923
-
Peroxisome proliferator-activated receptor gamma coactivator 1 alpha promoter polymorphisms are associated with early-onset type 2 diabetes mellitus in the Korean population
-
DOI 10.1007/s00125-005-1793-4
-
Kim JH, Shin HD, Park BL, Cho YM, Kim SY, Lee HK, Park KS (2005) Peroxisome proliferator-activated receptor gamma coactivator 1 alpha promoter polymorphisms are associated with early-onset type 2 diabetes mellitus in the Korean population. Diabetologia 48:1323-1330 (Pubitemid 41186097)
-
(2005)
Diabetologia
, vol.48
, Issue.7
, pp. 1323-1330
-
-
Kim, J.H.1
Shin, H.D.2
Park, B.L.3
Cho, Y.M.4
Kim, S.Y.5
Lee, H.K.6
Park, K.S.7
-
158
-
-
2342625303
-
Complex Haplotypes of the PGC-1alpha Gene Are Associated with Carbohydrate Metabolism and Type 2 Diabetes
-
DOI 10.2337/diabetes.53.5.1385
-
Oberkofler H, Linnemayr V, Weitgasser R, Klein K, Xie M, Iglseder B, Krempler F, Paulweber B, Patsch W (2004) Complex haplotypes of the PGC-1alpha gene are associated with carbohydrate metabolism and type 2 diabetes. Diabetes 53:1385-1393 (Pubitemid 38569027)
-
(2004)
Diabetes
, vol.53
, Issue.5
, pp. 1385-1393
-
-
Oberkofler, H.1
Linnemayr, V.2
Weitgasser, R.3
Klein, K.4
Xie, M.5
Iglseder, B.6
Krempler, F.7
Paulweber, B.8
Patsch, W.9
-
159
-
-
33751400561
-
Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance
-
DOI 10.1016/j.cmet.2006.11.003, PII S1550413106003652
-
Vianna CR, Huntgeburth M, Coppari R, Choi CS, Lin J, Krauss S, Barbatelli G, Tzameli I, Kim YB, Cinti S, Shulman GI, Spiegelman BM, Lowell BB (2006) Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance. Cell Metab 4:453-464 (Pubitemid 44817352)
-
(2006)
Cell Metabolism
, vol.4
, Issue.6
, pp. 453-464
-
-
Vianna, C.R.1
Huntgeburth, M.2
Coppari, R.3
Choi, C.S.4
Lin, J.5
Krauss, S.6
Barbatelli, G.7
Tzameli, I.8
Kim, Y.-B.9
Cinti, S.10
Shulman, G.I.11
Spiegelman, B.M.12
Lowell, B.B.13
-
160
-
-
21044442671
-
Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity
-
DOI 10.1136/jmg.2004.026278
-
Andersen G, Wegner L, Yanagisawa K, Rose CS, Lin J, Glumer C, Drivsholm T, Borch-Johnsen K, Jorgensen T, Hansen T, Spiegelman BM, Pedersen O (2005) Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity. J Med Genet 42:402-407 (Pubitemid 40685681)
-
(2005)
Journal of Medical Genetics
, vol.42
, Issue.5
, pp. 402-407
-
-
Andersen, G.1
Wegner, L.2
Yanagisawa, K.3
Rose, C.S.4
Lin, J.5
Glumer, C.6
Drivsholm, T.7
Borch-Johnsen, K.8
Jorgensen, T.9
Hansen, T.10
Spiegelman, B.M.11
Pedersen, O.12
-
161
-
-
34447120855
-
Impact of the peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) Ala203Pro polymorphism on in vivo metabolism, PGC-1beta expression and fibre type composition in human skeletal muscle
-
DOI 10.1007/s00125-007-0729-6
-
Ling C, Wegner L, Andersen G, Almgren P, Hansen T, Pedersen O, Groop L, Vaag A, Poulsen P (2007) Impact of the peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) Ala203Pro polymorphism on in vivo metabolism, PGC-1beta expression and fibre type composition in human skeletal muscle. Diabetologia 50:1615-1620 (Pubitemid 47036667)
-
(2007)
Diabetologia
, vol.50
, Issue.8
, pp. 1615-1620
-
-
Ling, C.1
Wegner, L.2
Andersen, G.3
Almgren, P.4
Hansen, T.5
Pedersen, O.6
Groop, L.7
Vaag, A.8
Poulsen, P.9
-
162
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
DOI 10.1038/nature05354, PII NATURE05354
-
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444:337-342 (Pubitemid 44764104)
-
(2006)
Nature
, vol.444
, Issue.7117
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le, C.D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
De Cabo, R.26
Sinclair, D.A.27
more..
-
163
-
-
33845399894
-
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1alpha
-
DOI 10.1016/j.cell.2006.11.013, PII S0092867406014280
-
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J (2006) Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell 127:1109-1122 (Pubitemid 44894520)
-
(2006)
Cell
, vol.127
, Issue.6
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
164
-
-
53049085274
-
PGC-1alpha integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscle
-
Pagel-Langenickel I, Bao J, Joseph JJ, Schwartz DR, Mantell BS, Xu X, Raghavachari N, Sack MN (2008) PGC-1alpha integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscle. J Biol Chem 283:22464-22472
-
(2008)
J Biol Chem
, vol.283
, pp. 22464-22472
-
-
Pagel-Langenickel, I.1
Bao, J.2
Joseph, J.J.3
Schwartz, D.R.4
Mantell, B.S.5
Xu, X.6
Raghavachari, N.7
Sack, M.N.8
-
165
-
-
68649109608
-
The biology of PGC-1alpha and its therapeutic potential
-
Handschin C (2009) The biology of PGC-1alpha and its therapeutic potential. Trends Pharmacol Sci 30:322-329
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 322-329
-
-
Handschin, C.1
-
166
-
-
54949101585
-
Cytokines and their relationship to the symptoms and outcome of cancer
-
Seruga B, Zhang H, Bernstein LJ, Tannock IF (2008) Cytokines and their relationship to the symptoms and outcome of cancer. Nat Rev Cancer 8:887-899
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 887-899
-
-
Seruga, B.1
Zhang, H.2
Bernstein, L.J.3
Tannock, I.F.4
-
167
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11:373-384
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
168
-
-
84856641109
-
NF-kappaB, the first quarter-century: Remarkable progress and outstanding questions
-
Hayden MS, Ghosh S (2012) NF-kappaB, the first quarter-century: remarkable progress and outstanding questions. Gene Dev 26:203-234
-
(2012)
Gene Dev
, vol.26
, pp. 203-234
-
-
Hayden, M.S.1
Ghosh, S.2
-
169
-
-
0037044575
-
The IkappaB-NF-kappaB signaling module: Temporal control and selective gene activation
-
DOI 10.1126/science.1071914
-
Hoffmann A, Levchenko A, Scott ML, Baltimore D (2002) The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science 298:1241-1245 (Pubitemid 35285493)
-
(2002)
Science
, vol.298
, Issue.5596
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
-
170
-
-
0027462682
-
Mutual regulation of the transcriptional activator NF-kappaB and its inhibitor, IkappaB-alpha
-
Brown K, Park S, Kanno T, Franzoso G, Siebenlist U (1993) Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha. Proc Natl Acad Sci U S A 90:2532-2536 (Pubitemid 23078662)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.6
, pp. 2532-2536
-
-
Brown, K.1
Park, S.2
Kanno, T.3
Franzoso, G.4
Siebenlist, U.5
-
171
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IkappaB kinases essential for NF-kappaB activation
-
DOI 10.1126/science.278.5339.860
-
Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li J, Young DB, Barbosa M, Mann M, Manning A, Rao A (1997) IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NFkappaB activation. Science 278:860-866 (Pubitemid 27467923)
-
(1997)
Science
, vol.278
, Issue.5339
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
Shevchenko, A.4
Bennett, B.L.5
Li, J.W.6
Young, D.B.7
Barbosa, M.8
Mann, M.9
Manning, A.10
Rao, A.11
-
172
-
-
17944378526
-
Activation by IKKalpha of a second, evolutionary conserved, NF-kappaB signaling pathway
-
DOI 10.1126/science.1062677
-
Senftleben U, Cao Y, Xiao G, Greten FR, Krahn G, Bonizzi G, Chen Y, Hu Y, Fong A, Sun SC, Karin M (2001) Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science 293:1495-1499 (Pubitemid 32801552)
-
(2001)
Science
, vol.293
, Issue.5534
, pp. 1495-1499
-
-
Senftleben, U.1
Cao, Y.2
Xiao, G.3
Greten, F.R.4
Krahn, G.5
Bonizzi, G.6
Chen, Y.7
Hu, Y.8
Fong, A.9
Sun, S.-C.10
Karin, M.11
-
173
-
-
0034745420
-
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100
-
DOI 10.1016/S1097-2765(01)00187-3
-
Xiao G, Harhaj EW, Sun SC (2001) NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol Cell 7:401-409 (Pubitemid 32206507)
-
(2001)
Molecular Cell
, vol.7
, Issue.2
, pp. 401-409
-
-
Xiao, G.1
Harhaj, E.W.2
Sun, S.-C.3
-
174
-
-
0037107399
-
CD40 regulates the processing of NF-kappaB2 p100 to p52
-
DOI 10.1093/emboj/cdf542
-
Coope HJ, Atkinson PG, Huhse B, Belich M, Janzen J, Holman MJ, Klaus GG, Johnston LH, Ley SC (2002) CD40 regulates the processing of NF-kappaB2 p100 to p52. EMBO J 21:5375-5385 (Pubitemid 35231017)
-
(2002)
EMBO Journal
, vol.21
, Issue.20
, pp. 5375-5385
-
-
Coope, H.J.1
Atkinson, P.G.P.2
Huhse, B.3
Belich, M.4
Janzen, J.5
Holman, M.J.6
Klaus, G.G.B.7
Johnston, L.H.8
Ley, S.C.9
-
175
-
-
18644380147
-
The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways
-
DOI 10.1016/S1074-7613(02)00423-5
-
Dejardin E, Droin NM, Delhase M, Haas E, Cao Y, Makris C, Li ZW, Karin M, Ware CF, Green DR (2002) The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity 17:525-535 (Pubitemid 35223540)
-
(2002)
Immunity
, vol.17
, Issue.4
, pp. 525-535
-
-
Dejardin, E.1
Droin, N.M.2
Delhase, M.3
Haas, E.4
Cao, Y.5
Makris, C.6
Li, Z.-W.7
Karin, M.8
Ware, C.F.9
Green, D.R.10
-
176
-
-
0036794398
-
BAFF-induced NEMO-independent processing of NF-kappaB2 in maturing B cells
-
DOI 10.1038/ni842
-
Claudio E, Brown K, Park S, Wang H, Siebenlist U (2002) BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells. Nat Immunol 3:958-965 (Pubitemid 35154010)
-
(2002)
Nature Immunology
, vol.3
, Issue.10
, pp. 958-965
-
-
Claudio, E.1
Brown, K.2
Park, S.3
Wang, H.4
Siebenlist, U.5
-
177
-
-
0024503589
-
Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha
-
DOI 10.1038/337661a0
-
Brenner DA, O'Hara M, Angel P, Chojkier M, Karin M (1989) Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha. Nature 337:661-663 (Pubitemid 19054296)
-
(1989)
Nature
, vol.337
, Issue.6208
, pp. 661-663
-
-
Brenner, D.A.1
O'Hara, M.2
Angel, P.3
Chojkier, M.4
Karin, M.5
-
178
-
-
28544434439
-
Fos/AP-1 proteins in bone and the immune system
-
Wagner EF, Eferl R (2005) Fos/AP-1 proteins in bone and the immune system. Immunol Rev 208:126-140 (Pubitemid 41746389)
-
(2005)
Immunological Reviews
, vol.208
, pp. 126-140
-
-
Wagner, E.F.1
Eferl, R.2
-
179
-
-
33748051738
-
IRFs: Master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
-
DOI 10.1038/nri1900, PII NRI1900
-
Honda K, Taniguchi T (2006) IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol 6:644-658 (Pubitemid 44298214)
-
(2006)
Nature Reviews Immunology
, vol.6
, Issue.9
, pp. 644-658
-
-
Honda, K.1
Taniguchi, T.2
-
180
-
-
0347955360
-
Regulation of NF-kappaB Signaling by Pin1-Dependent Prolyl Isomerization and Ubiquitin-Mediated Proteolysis of p65/RelA
-
DOI 10.1016/S1097-2765(03)00490-8
-
Ryo A, Suizu F, Yoshida Y, Perrem K, Liou YC, Wulf G, Rottapel R, Yamaoka S, Lu KP (2003) Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol Cell 12:1413-1426 (Pubitemid 38037011)
-
(2003)
Molecular Cell
, vol.12
, Issue.6
, pp. 1413-1426
-
-
Ryo, A.1
Suizu, F.2
Yoshida, Y.3
Perrem, K.4
Liou, Y.-C.5
Wulf, G.6
Rottapel, R.7
Yamaoka, S.8
Lu, K.P.9
-
181
-
-
0034730713
-
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice
-
Lee EG, Boone DL, Chai S, Libby SL, Chien M, Lodolce JP, Ma A (2000) Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice. Science 289:2350-2354
-
(2000)
Science
, vol.289
, pp. 2350-2354
-
-
Lee, E.G.1
Boone, D.L.2
Chai, S.3
Libby, S.L.4
Chien, M.5
Lodolce, J.P.6
Ma, A.7
-
182
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
-
DOI 10.1038/nature02794
-
Wertz IE, O'Rourke KM, Zhou H, Eby M, Aravind L, Seshagiri S, Wu P, Wiesmann C, Baker R, Boone DL, Ma A, Koonin EV, Dixit VM (2004) De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature 430:694-699 (Pubitemid 39061687)
-
(2004)
Nature
, vol.430
, Issue.7000
, pp. 694-699
-
-
Wartz, I.E.1
O'Rourke, K.M.2
Zhou, H.3
Eby, M.4
Aravind, L.5
Seshagiri, S.6
Wu, P.7
Wiesmann, C.8
Baker, R.9
Boone, D.L.10
Ma, A.11
Koonin, E.V.12
Dixit, V.M.13
-
183
-
-
0037039665
-
Distinct roles of the IkappaB kinase alpha and beta subunits in liberating nuclear factor kappaB (NF-kappaB) from IkappaB and in phosphorylating the p65 subunit of NF-kappaB
-
DOI 10.1074/jbc.M110572200
-
Sizemore N, Lerner N, Dombrowski N, Sakurai H, Stark GR (2002) Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B. J Biol Chem 277:3863-3869 (Pubitemid 34968637)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.6
, pp. 3863-3869
-
-
Sizemore, N.1
Lerner, N.2
Dombrowski, N.3
Sakurai, H.4
Stark, G.R.5
-
184
-
-
67349245931
-
WIP1 phosphatase is a negative regulator of NF-kappaB signalling
-
Chew J, Biswas S, Shreeram S, Humaidi M, Wong ET, Dhillion MK, Teo H, Hazra A, Fang CC, Lopez-Collazo E, Bulavin DV, Tergaonkar V (2009) WIP1 phosphatase is a negative regulator of NF-kappaB signalling. Nat Cell Biol 11:659-666
-
(2009)
Nat Cell Biol
, vol.11
, pp. 659-666
-
-
Chew, J.1
Biswas, S.2
Shreeram, S.3
Humaidi, M.4
Wong, E.T.5
Dhillion, M.K.6
Teo, H.7
Hazra, A.8
Fang, C.C.9
Lopez-Collazo, E.10
Bulavin, D.V.11
Tergaonkar, V.12
-
185
-
-
0032565868
-
Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators
-
DOI 10.1038/31701
-
Staels B, Koenig W, Habib A, Merval R, Lebret M, Torra IP, Delerive P, Fadel A, Chinetti G, Fruchart JC, Najib J, Maclouf J, Tedgui A (1998) Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators. Nature 393:790-793 (Pubitemid 28299490)
-
(1998)
Nature
, vol.393
, Issue.6687
, pp. 790-793
-
-
Staels, B.1
Koenig, W.2
Habib, A.3
Merval, R.4
Lebret, M.5
Torra, I.P.6
Delerive, P.7
Fadel, A.8
Chinetti, G.9
Fruchart, J.-C.10
Najib, J.11
Maclouf, J.12
Tedgui, A.13
-
186
-
-
0033594810
-
PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells
-
Marx N, Sukhova GK, Collins T, Libby P, Plutzky J (1999) PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation 99:3125-3131 (Pubitemid 29289077)
-
(1999)
Circulation
, vol.99
, Issue.24
, pp. 3125-3131
-
-
Marx, N.1
Sukhova, G.K.2
Collins, T.3
Libby, P.4
Plutzky, J.5
-
187
-
-
0033527569
-
Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1
-
Delerive P, De Bosscher K, Besnard S, Vanden Berghe W, Peters JM, Gonzalez FJ, Fruchart JC, Tedgui A, Haegeman G, Staels B (1999) Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J Biol Chem 274:32048-32054
-
(1999)
J Biol Chem
, vol.274
, pp. 32048-32054
-
-
Delerive, P.1
De Bosscher, K.2
Besnard, S.3
Vanden Berghe, W.4
Peters, J.M.5
Gonzalez, F.J.6
Fruchart, J.C.7
Tedgui, A.8
Haegeman, G.9
Staels, B.10
-
188
-
-
0031888958
-
PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
-
DOI 10.1038/34184
-
Jiang C, Ting AT, Seed B (1998) PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391:82-86 (Pubitemid 28079219)
-
(1998)
Nature
, vol.391
, Issue.6662
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
189
-
-
0031886864
-
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
-
DOI 10.1038/34178
-
Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK (1998) The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391:79-82 (Pubitemid 28079218)
-
(1998)
Nature
, vol.391
, Issue.6662
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
190
-
-
0025130179
-
Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor
-
Schule R, Rangarajan P, Kliewer S, Ransone LJ, Bolado J, Yang N, Verma IM, Evans RM (1990) Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell 62:1217-1226
-
(1990)
Cell
, vol.62
, pp. 1217-1226
-
-
Schule, R.1
Rangarajan, P.2
Kliewer, S.3
Ransone, L.J.4
Bolado, J.5
Yang, N.6
Verma, I.M.7
Evans, R.M.8
-
191
-
-
0025015647
-
Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
-
Jonat C, Rahmsdorf HJ, Park KK, Cato AC, Gebel S, Ponta H, Herrlich P (1990) Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell 62:1189-1204
-
(1990)
Cell
, vol.62
, pp. 1189-1204
-
-
Jonat, C.1
Rahmsdorf, H.J.2
Park, K.K.3
Cato, A.C.4
Gebel, S.5
Ponta, H.6
Herrlich, P.7
-
192
-
-
0028867899
-
Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis
-
Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M (1995) Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 270:286-290
-
(1995)
Science
, vol.270
, pp. 286-290
-
-
Auphan, N.1
DiDonato, J.A.2
Rosette, C.3
Helmberg, A.4
Karin, M.5
-
193
-
-
0028879819
-
Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
-
Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS Jr (1995) Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270:283-286
-
(1995)
Science
, vol.270
, pp. 283-286
-
-
Scheinman, R.I.1
Cogswell, P.C.2
Lofquist, A.K.3
Baldwin Jr., A.S.4
-
194
-
-
0036255486
-
DNA binding-independent induction of IkappaBalpha gene transcription by PPARalpha
-
DOI 10.1210/me.16.5.1029
-
Delerive P, De Bosscher K, Vanden Berghe W, Fruchart JC, Haegeman G, Staels B (2002) DNA binding-independent induction of IkappaBalpha gene transcription by PPARalpha. Mol Endocrinol 16:1029-1039 (Pubitemid 34478539)
-
(2002)
Molecular Endocrinology
, vol.16
, Issue.5
, pp. 1029-1039
-
-
Delerive, P.1
De Bosscher, K.2
Berghe, W.V.3
Fruchart, J.-C.4
Haegeman, G.5
Staels, B.6
-
195
-
-
0242587820
-
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
-
DOI 10.1016/S0092-8674(00)81118-6
-
Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, Lin SC, Heyman RA, Rose DW, Glass CK, Rosenfeld MG (1996) A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403-414 (Pubitemid 26160711)
-
(1996)
Cell
, vol.85
, Issue.3
, pp. 403-414
-
-
Kamei, Y.1
Xu, L.2
Heinzel, T.3
Torchia, J.4
Kurokawa, R.5
Gloss, B.6
Lin, S.-C.7
Heyman, R.A.8
Rose, D.W.9
Glass, C.K.10
Rosenfeld, M.G.11
-
196
-
-
0032491483
-
Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1
-
DOI 10.1074/jbc.273.45.29291
-
Sheppard KA, Phelps KM, Williams AJ, Thanos D, Glass CK, Rosenfeld MG, Gerritsen ME, Collins T (1998) Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1. J Biol Chem 273:29291-29294 (Pubitemid 28509926)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.45
, pp. 29291-29294
-
-
Sheppard, K.-A.1
Phelps, K.M.2
Williams, A.J.3
Thanos, D.4
Glass, C.K.5
Rosenfeld, M.G.6
Gerritsen, M.E.7
Collins, T.8
-
197
-
-
24144465889
-
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors
-
DOI 10.1016/j.cell.2005.06.029, PII S0092867405006483
-
Ogawa S, Lozach J, Benner C, Pascual G, Tangirala RK, Westin S, Hoffmann A, Subramaniam S, David M, Rosenfeld MG, Glass CK (2005) Molecular determinants of crosstalk between nuclear receptors and Toll-like receptors. Cell 122:707-721 (Pubitemid 41242636)
-
(2005)
Cell
, vol.122
, Issue.5
, pp. 707-721
-
-
Ogawa, S.1
Lozach, J.2
Benner, C.3
Pascual, G.4
Tangirala, R.K.5
Westin, S.6
Hoffmann, A.7
Subramaniam, S.8
David, M.9
Rosenfeld, M.G.10
Glass, C.K.11
-
198
-
-
5444233785
-
A nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1- and NF-kappaB-regulated promoters
-
DOI 10.1101/gad.322404
-
Kassel O, Schneider S, Heilbock C, Litfin M, Gottlicher M, Herrlich P (2004) A nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1-and NF-kappaB-regulated promoters. Genes Dev 18:2518-2528 (Pubitemid 39362894)
-
(2004)
Genes and Development
, vol.18
, Issue.20
, pp. 2518-2528
-
-
Kassel, O.1
Schneider, S.2
Heilbock, C.3
Litfin, M.4
Gottlicher, M.5
Herrlich, P.6
-
199
-
-
0037168648
-
Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts
-
DOI 10.1073/pnas.262671599
-
Rogatsky I, Luecke HF, Leitman DC, Yamamoto KR (2002) Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts. Proc Natl Acad Sci U S A 99:16701-16706 (Pubitemid 36034036)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.26
, pp. 16701-16706
-
-
Rogatsky, I.1
Luecke, H.F.2
Leitman, D.C.3
Yamamoto, K.R.4
-
200
-
-
63049083734
-
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death
-
Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG, Gage FH, Glass CK (2009) A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell 137:47-59
-
(2009)
Cell
, vol.137
, pp. 47-59
-
-
Saijo, K.1
Winner, B.2
Carson, C.T.3
Collier, J.G.4
Boyer, L.5
Rosenfeld, M.G.6
Gage, F.H.7
Glass, C.K.8
-
201
-
-
26444471700
-
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma
-
DOI 10.1038/nature03988, PII N03988
-
Pascual G, Fong AL, Ogawa S, Gamliel A, Li AC, Perissi V, Rose DW, Willson TM, Rosenfeld MG, Glass CK (2005) A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature 437:759-763 (Pubitemid 41486547)
-
(2005)
Nature
, vol.437
, Issue.7059
, pp. 759-763
-
-
Pascual, G.1
Fong, A.L.2
Ogawa, S.3
Gamliel, A.4
Li, A.C.5
Perissi, V.6
Rose, D.W.7
Willson, T.M.8
Rosenfeld, M.G.9
Glass, C.K.10
-
202
-
-
33845970925
-
Parallel SUMOylation-Dependent Pathways Mediate Gene- and Signal-Specific Transrepression by LXRs and PPARgamma
-
DOI 10.1016/j.molcel.2006.11.022, PII S1097276506008161
-
Ghisletti S, Huang W, Ogawa S, Pascual G, Lin ME, Willson TM, Rosenfeld MG, Glass CK (2007) Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma. Mol Cell 25:57-70 (Pubitemid 46049061)
-
(2007)
Molecular Cell
, vol.25
, Issue.1
, pp. 57-70
-
-
Ghisletti, S.1
Huang, W.2
Ogawa, S.3
Pascual, G.4
Lin, M.-E.5
Willson, T.M.6
Rosenfeld, M.G.7
Glass, C.K.8
-
203
-
-
70349191359
-
Differential SUMOylation of LXRalpha and LXRbeta mediates transrepression of STAT1 inflammatory signaling in IFN-gamma-stimulated brain astrocytes
-
Lee JH, Park SM, Kim OS, Lee CS, Woo JH, Park SJ, Joe EH, Jou I (2009) Differential SUMOylation of LXRalpha and LXRbeta mediates transrepression of STAT1 inflammatory signaling in IFN-gamma-stimulated brain astrocytes. Mol Cell 35:806-817
-
(2009)
Mol Cell
, vol.35
, pp. 806-817
-
-
Lee, J.H.1
Park, S.M.2
Kim, O.S.3
Lee, C.S.4
Woo, J.H.5
Park, S.J.6
Joe, E.H.7
Jou, I.8
-
204
-
-
0033520304
-
Peroxisome proliferator-activated receptor activators inhibit thrombin- induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway
-
Delerive P, Martin-Nizard F, Chinetti G, Trottein F, Fruchart JC, Najib J, Duriez P, Staels B (1999) Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway. Circ Res 85:394-402 (Pubitemid 29409616)
-
(1999)
Circulation Research
, vol.85
, Issue.5
, pp. 394-402
-
-
Delerive, P.1
Martin-Nizard, F.2
Chinetti, G.3
Trottein, F.4
Fruchart, J.-C.5
Najib, J.6
Duriez, P.7
Staels, B.8
-
205
-
-
0034665748
-
The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain
-
Nissen RM, Yamamoto KR (2000) The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev 14:2314-2329
-
(2000)
Genes Dev
, vol.14
, pp. 2314-2329
-
-
Nissen, R.M.1
Yamamoto, K.R.2
-
206
-
-
18244381020
-
The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression
-
DOI 10.1101/gad.1297105
-
Luecke HF, Yamamoto KR (2005) The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression. Genes Dev 19:1116-1127 (Pubitemid 40632456)
-
(2005)
Genes and Development
, vol.19
, Issue.9
, pp. 1116-1127
-
-
Luecke, H.F.1
Yamamoto, K.R.2
-
207
-
-
0033821409
-
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12
-
Ito K, Barnes PJ, Adcock IM (2000) Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12. Mol Cell Biol 20:6891-6903
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6891-6903
-
-
Ito, K.1
Barnes, P.J.2
Adcock, I.M.3
-
208
-
-
31344446119
-
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
-
DOI 10.1084/jem.20050466
-
Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, Barnes PJ, Adcock IM (2006) Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med 203:7-13 (Pubitemid 43139638)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.1
, pp. 7-13
-
-
Ito, K.1
Yamamura, S.2
Essilfie-Quaye, S.3
Cosio, B.4
Ito, M.5
Barnes, P.J.6
Adcock, I.M.7
-
209
-
-
79751496064
-
Alternative macrophage activation and metabolism
-
Odegaard JI, Chawla A (2011) Alternative macrophage activation and metabolism. Annu Rev Pathol 6:275-297
-
(2011)
Annu Rev Pathol
, vol.6
, pp. 275-297
-
-
Odegaard, J.I.1
Chawla, A.2
-
210
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factoralpha in human obesity and insulin resistance
-
Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM (1995) Increased adipose tissue expression of tumor necrosis factoralpha in human obesity and insulin resistance. J Clin Invest 95:2409-2415
-
(1995)
J Clin Invest
, vol.95
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
211
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
-
Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM(1996) IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271:665-668 (Pubitemid 26052915)
-
(1996)
Science
, vol.271
, Issue.5249
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
212
-
-
0037153158
-
A central, role for JNK in obesity and insulin resistance
-
DOI 10.1038/nature01137
-
Hirosumi J, Tuncman G, Chang L, Gorgun CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS (2002) A central role for JNK in obesity and insulin resistance. Nature 420:333-336 (Pubitemid 35398190)
-
(2002)
Nature
, vol.420
, Issue.6913
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Gorgun, C.Z.4
Uysal, K.T.5
Maeda, K.6
Karin, M.7
Hotamisligil, G.S.8
-
213
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF- alpha function
-
DOI 10.1038/39335
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS (1997) Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 389:610-614 (Pubitemid 27446179)
-
(1997)
Nature
, vol.389
, Issue.6651
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
214
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
DOI 10.1172/JCI28898
-
Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS (2006) TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 116:3015-3025 (Pubitemid 44684486)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.11
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
215
-
-
85030434746
-
Increased oxidative stress in obesity and its impact on metabolic syndrome
-
DOI 10.1172/JCI200421625
-
Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, Nakayama O, Makishima M, Matsuda M, Shimomura I (2004) Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest 114:1752-1761 (Pubitemid 40385531)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.12
, pp. 1752-1761
-
-
Furukawa, S.1
Fujita, T.2
Shimabukuro, M.3
Iwaki, M.4
Yamada, Y.5
Nakajima, Y.6
Nakayama, O.7
Makishima, M.8
Matsuda, M.9
Shimomura, I.10
-
216
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
DOI 10.1126/science.1103160
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, Hotamisligil GS (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306:457-461 (Pubitemid 39372439)
-
(2004)
Science
, vol.306
, Issue.5695
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.-H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Gorgun, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
217
-
-
70349484670
-
Mechanisms of obesity and related pathologies: The macro- and microcirculation of adipose tissue
-
Rutkowski JM, Davis KE, Scherer PE (2009) Mechanisms of obesity and related pathologies: the macro- and microcirculation of adipose tissue. FEBS J 276:5738-5746
-
(2009)
FEBS J
, vol.276
, pp. 5738-5746
-
-
Rutkowski, J.M.1
Davis, K.E.2
Scherer, P.E.3
-
218
-
-
27444437321
-
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
-
DOI 10.1194/jlr.M500294-JLR200
-
Cinti S, Mitchell G, Barbatelli G, Murano I, Ceresi E, Faloia E, Wang S, Fortier M, Greenberg AS, Obin MS (2005) Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 46:2347-2355 (Pubitemid 41532523)
-
(2005)
Journal of Lipid Research
, vol.46
, Issue.11
, pp. 2347-2355
-
-
Cinti, S.1
Mitchell, G.2
Barbatelli, G.3
Murano, I.4
Ceresi, E.5
Faloia, E.6
Wang, S.7
Fortier, M.8
Greenberg, A.S.9
Obin, M.S.10
-
219
-
-
44349112305
-
Adipocyte-Derived Th2 Cytokines and Myeloid PPARdelta Regulate Macrophage Polarization and Insulin Sensitivity
-
DOI 10.1016/j.cmet.2008.04.002, PII S1550413108001125
-
Kang K, Reilly SM, Karabacak V, Gangl MR, Fitzgerald K, Hatano B, Lee CH (2008) Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulatemacrophage polarization and insulin sensitivity. Cell Metab 7:485-495 (Pubitemid 351729204)
-
(2008)
Cell Metabolism
, vol.7
, Issue.6
, pp. 485-495
-
-
Kang, K.1
Reilly, S.M.2
Karabacak, V.3
Gangl, M.R.4
Fitzgerald, K.5
Hatano, B.6
Lee, C.-H.7
-
220
-
-
77949881805
-
Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype
-
Ohashi K, Parker JL, Ouchi N, Higuchi A, Vita JA, Gokce N, Pedersen AA, Kalthoff C, Tullin S, Sams A, Summer R, Walsh K (2010) Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. J Biol Chem 285:6153-6160
-
(2010)
J Biol Chem
, vol.285
, pp. 6153-6160
-
-
Ohashi, K.1
Parker, J.L.2
Ouchi, N.3
Higuchi, A.4
Vita, J.A.5
Gokce, N.6
Pedersen, A.A.7
Kalthoff, C.8
Tullin, S.9
Sams, A.10
Summer, R.11
Walsh, K.12
-
221
-
-
59749096280
-
Dietary interventions for metabolic syndrome: Role of modifying dietary fats
-
Kien CL (2009) Dietary interventions for metabolic syndrome: role of modifying dietary fats. Curr Diabet Rep 9:43-50
-
(2009)
Curr Diabet Rep
, vol.9
, pp. 43-50
-
-
Kien, C.L.1
-
222
-
-
34347354309
-
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
-
DOI 10.1038/nature05894, PII NATURE05894
-
Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, Red Eagle A, Vats D, Brombacher F, Ferrante AW, Chawla A (2007) Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature 447:1116-1120 (Pubitemid 47014427)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subramanian, V.5
Mukundan, L.6
Eagle, A.R.7
Vats, D.8
Brombacher, F.9
Ferrante, A.W.10
Chawla, A.11
-
223
-
-
33745428666
-
Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation
-
DOI 10.1016/j.cmet.2006.05.011, PII S1550413106002026
-
Vats D, Mukundan L, Odegaard JI, Zhang L, Smith KL, Morel CR, Wagner RA, Greaves DR, Murray PJ, Chawla A (2006) Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation. Cell Metab 4:13-24 (Pubitemid 43942258)
-
(2006)
Cell Metabolism
, vol.4
, Issue.1
, pp. 13-24
-
-
Vats, D.1
Mukundan, L.2
Odegaard, J.I.3
Zhang, L.4
Smith, K.L.5
Morel, C.R.6
Greaves, D.R.7
Murray, P.J.8
Chawla, A.9
-
224
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
DOI 10.1172/JCI200319246
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr (2003) Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112:1796-1808 (Pubitemid 38063703)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
225
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
DOI 10.1172/JCI200319451
-
Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112:1821-1830 (Pubitemid 38063705)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
226
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
DOI 10.1172/JCI29881
-
Lumeng CN, Bodzin JL, Saltiel AR (2007) Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 117:175-184 (Pubitemid 46048464)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
227
-
-
33748750917
-
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance
-
DOI 10.1074/jbc.M601284200
-
Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T (2006) Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance. J Biol Chem 281:26602-26614 (Pubitemid 44401869)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.36
, pp. 26602-26614
-
-
Kamei, N.1
Tobe, K.2
Suzuki, R.3
Ohsugi, M.4
Watanabe, T.5
Kubota, N.6
Ohtsuka-Kowatari, N.7
Kumagai, K.8
Sakamoto, K.9
Kobayashi, M.10
Yamauchi, T.11
Ueki, K.12
Oishi, Y.13
Nishimura, S.14
Manabe, I.15
Hashimoto, H.16
Ohnishi, Y.17
Ogata, H.18
Tokuyama, K.19
Tsunoda, M.20
Ide, T.21
Murakami, K.22
Nagai, R.23
Kadowaki, T.24
more..
-
228
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
-
Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, Kitazawa R, Kitazawa S, Miyachi H, Maeda S, Egashira K, Kasuga M (2006) MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 116:1494-1505
-
(2006)
J Clin Invest
, vol.116
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
Kotani, K.4
Hiasa, K.5
Kitazawa, R.6
Kitazawa, S.7
Miyachi, H.8
Maeda, S.9
Egashira, K.10
Kasuga, M.11
-
229
-
-
31044456529
-
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
-
DOI 10.1172/JCI24335
-
Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, Charo I, Leibel RL, Ferrante AW Jr (2006) CCR2 modulates inflammatory andmetabolic effects of high-fat feeding. J Clin Invest 116:115-124 (Pubitemid 43121796)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.1
, pp. 115-124
-
-
Weisberg, S.P.1
Hunter, D.2
Huber, R.3
Lemieux, J.4
Slaymaker, S.5
Vaddi, K.6
Charo, I.7
Leibel, R.L.8
Ferrante Jr., A.W.9
-
230
-
-
70350389389
-
Hematopoietic cell-specific deletion of Toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice
-
Saberi M, Woods NB, de Luca C, Schenk S, Lu JC, Bandyopadhyay G, Verma IM, Olefsky JM (2009) Hematopoietic cell-specific deletion of Toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice. Cell Metab 10:419-429
-
(2009)
Cell Metab
, vol.10
, pp. 419-429
-
-
Saberi, M.1
Woods, N.B.2
De Luca, C.3
Schenk, S.4
Lu, J.C.5
Bandyopadhyay, G.6
Verma, I.M.7
Olefsky, J.M.8
-
231
-
-
35548943962
-
JNK1 in Hematopoietically Derived Cells Contributes to Diet-Induced Inflammation and Insulin Resistance without Affecting Obesity
-
DOI 10.1016/j.cmet.2007.09.011, PII S1550413107002926
-
Solinas G, Vilcu C, Neels JG, Bandyopadhyay GK, Luo JL, Naugler W, Grivennikov S, Wynshaw-Boris A, Scadeng M, Olefsky JM, Karin M (2007) JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity. Cell Metab 6:386-397 (Pubitemid 350012000)
-
(2007)
Cell Metabolism
, vol.6
, Issue.5
, pp. 386-397
-
-
Solinas, G.1
Vilcu, C.2
Neels, J.G.3
Bandyopadhyay, G.K.4
Luo, J.-L.5
Naugler, W.6
Grivennikov, S.7
Wynshaw-Boris, A.8
Scadeng, M.9
Olefsky, J.M.10
Karin, M.11
-
232
-
-
20044387026
-
IKK-beta links inflammation to obesity-induced insulin resistance
-
DOI 10.1038/nm1185
-
Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M (2005) IKK-beta links inflammation to obesity-induced insulin resistance. Nat Med 11:191-198 (Pubitemid 40321355)
-
(2005)
Nature Medicine
, vol.11
, Issue.2
, pp. 191-198
-
-
Arkan, M.C.1
Hevener, A.L.2
Greten, F.R.3
Maeda, S.4
Li, Z.-W.5
Long, J.M.6
Wynshaw-Boris, A.7
Poli, G.8
Olefsky, J.9
Karin, M.10
-
233
-
-
79953815551
-
Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis
-
Wu D, Molofsky AB, Liang HE, Ricardo-Gonzalez RR, Jouihan HA, Bando JK, Chawla A, Locksley RM(2011) Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis. Science 332:243-247
-
(2011)
Science
, vol.332
, pp. 243-247
-
-
Wu, D.1
Molofsky, A.B.2
Liang, H.E.3
Ricardo-Gonzalez, R.R.4
Jouihan, H.A.5
Bando, J.K.6
Chawla, A.7
Locksley, R.M.8
-
234
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
Winer S, Chan Y, Paltser G, Truong D, Tsui H, Bahrami J, Dorfman R, Wang Y, Zielenski J, Mastronardi F, Maezawa Y, Drucker DJ, Engleman E, Winer D, Dosch HM (2009) Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med 15:921-929
-
(2009)
Nat Med
, vol.15
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
Truong, D.4
Tsui, H.5
Bahrami, J.6
Dorfman, R.7
Wang, Y.8
Zielenski, J.9
Mastronardi, F.10
Maezawa, Y.11
Drucker, D.J.12
Engleman, E.13
Winer, D.14
Dosch, H.M.15
-
235
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
Feuerer M, Herrero L, Cipolletta D, Naaz A, Wong J, Nayer A, Lee J, Goldfine AB, Benoist C, Shoelson S, Mathis D (2009) Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 15:930-939
-
(2009)
Nat Med
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
Naaz, A.4
Wong, J.5
Nayer, A.6
Lee, J.7
Goldfine, A.B.8
Benoist, C.9
Shoelson, S.10
Mathis, D.11
-
236
-
-
54049086276
-
Interferon-gamma, a Th1 cytokine, regulates fat inflammation: A role for adaptive immunity in obesity
-
Rocha VZ, Folco EJ, Sukhova G, Shimizu K, Gotsman I, Vernon AH, Libby P (2008) Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity. Circ Res 103:467-476
-
(2008)
Circ Res
, vol.103
, pp. 467-476
-
-
Rocha, V.Z.1
Folco, E.J.2
Sukhova, G.3
Shimizu, K.4
Gotsman, I.5
Vernon, A.H.6
Libby, P.7
-
237
-
-
53149119231
-
Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding
-
Elgazar-Carmon V, Rudich A, Hadad N, Levy R (2008) Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding. J Lipid Res 49:1894-1903
-
(2008)
J Lipid Res
, vol.49
, pp. 1894-1903
-
-
Elgazar-Carmon, V.1
Rudich, A.2
Hadad, N.3
Levy, R.4
-
238
-
-
68349150756
-
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M, Otsu M, Hara K, Ueki K, Sugiura S, Yoshimura K, Kadowaki T, Nagai R (2009) CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 15:914-920
-
(2009)
Nat Med
, vol.15
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Eto, K.4
Yamashita, H.5
Ohsugi, M.6
Otsu, M.7
Hara, K.8
Ueki, K.9
Sugiura, S.10
Yoshimura, K.11
Kadowaki, T.12
Nagai, R.13
-
239
-
-
85027938385
-
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
-
Winer DA, Winer S, Shen L, Wadia PP, Yantha J, Paltser G, Tsui H, Wu P, Davidson MG, Alonso MN, Leong HX, Glassford A, Caimol M, Kenkel JA, Tedder TF, McLaughlin T, Miklos DB, Dosch HM, Engleman EG (2011) B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. Nat Med 17:610-617
-
(2011)
Nat Med
, vol.17
, pp. 610-617
-
-
Winer, D.A.1
Winer, S.2
Shen, L.3
Wadia, P.P.4
Yantha, J.5
Paltser, G.6
Tsui, H.7
Wu, P.8
Davidson, M.G.9
Alonso, M.N.10
Leong, H.X.11
Glassford, A.12
Caimol, M.13
Kenkel, J.A.14
Tedder, T.F.15
McLaughlin, T.16
Miklos, D.B.17
Dosch, H.M.18
Engleman, E.G.19
-
240
-
-
77953110535
-
Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice
-
Ilan Y, Maron R, Tukpah AM, Maioli TU, Murugaiyan G, Yang K, Wu HY, Weiner HL (2010) Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice. Proc Natl Acad Sci U S A 107:9765-9770
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 9765-9770
-
-
Ilan, Y.1
Maron, R.2
Tukpah, A.M.3
Maioli, T.U.4
Murugaiyan, G.5
Yang, K.6
Wu, H.Y.7
Weiner, H.L.8
-
241
-
-
84859449180
-
Saturated fatty acid and TLR signaling link beta cell dysfunction and islet inflammation
-
Eguchi K, Manabe I, Oishi-Tanaka Y, Ohsugi M, Kono N, Ogata F, Yagi N, Ohto U, Kimoto M, Miyake K, Tobe K, Arai H, Kadowaki T, Nagai R (2012) Saturated fatty acid and TLR signaling link beta cell dysfunction and islet inflammation. Cell Metab 15:518-533
-
(2012)
Cell Metab
, vol.15
, pp. 518-533
-
-
Eguchi, K.1
Manabe, I.2
Oishi-Tanaka, Y.3
Ohsugi, M.4
Kono, N.5
Ogata, F.6
Yagi, N.7
Ohto, U.8
Kimoto, M.9
Miyake, K.10
Tobe, K.11
Arai, H.12
Kadowaki, T.13
Nagai, R.14
-
242
-
-
52749092267
-
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
-
Patsouris D, Li PP, Thapar D, Chapman J, Olefsky JM, Neels JG (2008) Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metab 8:301-309
-
(2008)
Cell Metab
, vol.8
, pp. 301-309
-
-
Patsouris, D.1
Li, P.P.2
Thapar, D.3
Chapman, J.4
Olefsky, J.M.5
Neels, J.G.6
-
243
-
-
34249907880
-
Macrophage PPARgamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
-
DOI 10.1172/JCI31561
-
Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, Folian B, Subramaniam S, Gonzalez FJ, Glass CK, Ricote M (2007) Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J Clin Invest 117:1658-1669 (Pubitemid 46871350)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.6
, pp. 1658-1669
-
-
Hevener, A.L.1
Olefsky, J.M.2
Reichart, D.3
Nguyen, M.T.A.4
Bandyopadyhay, G.5
Leung, H.-Y.6
Watt, M.J.7
Benner, C.8
Febbraio, M.A.9
Nguyen, A.-K.10
Folian, B.11
Subramaniam, S.12
Gonzalez, F.J.13
Glass, C.K.14
Ricote, M.15
-
244
-
-
1642423481
-
p38 MAPK-induced Nuclear Factor-kappaB Activity Is Required for Skeletal Muscle Differentiation: Role of Interleukin-6
-
DOI 10.1091/mbc.E03-08-0585
-
Baeza-Raja B, Munoz-Canoves P (2004) p38 MAPK-induced nuclear factor-kappaB activity is required for skeletal muscle differentiation: role of interleukin-6. Mol Biol Cell 15:2013-2026 (Pubitemid 38401847)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.4
, pp. 2013-2026
-
-
Baeza-Raja, B.1
Munoz-Canoves, P.2
-
245
-
-
0035827711
-
Nuclear factor kappa B-inducing kinase and Ikappa B kinase-alpha signal skeletal muscle cell differentiation
-
Canicio J, Ruiz-Lozano P, Carrasco M, Palacin M, Chien K, Zorzano A, Kaliman P (2001) Nuclear factor kappa B-inducing kinase and Ikappa B kinase-alpha signal skeletal muscle cell differentiation. J Biol Chem 276:20228-20233
-
(2001)
J Biol Chem
, vol.276
, pp. 20228-20233
-
-
Canicio, J.1
Ruiz-Lozano, P.2
Carrasco, M.3
Palacin, M.4
Chien, K.5
Zorzano, A.6
Kaliman, P.7
-
246
-
-
0035196116
-
Insulin produces myogenesis in C2C12 myoblasts by induction of NFkappaB and downregulation of AP-1 activities
-
Conejo R, Valverde AM, Benito M, Lorenzo M (2001) Insulin produces myogenesis in C2C12 myoblasts by induction of NFkappaB and downregulation of AP-1 activities. J Cell Physiol 186:82-94
-
(2001)
J Cell Physiol
, vol.186
, pp. 82-94
-
-
Conejo, R.1
Valverde, A.M.2
Benito, M.3
Lorenzo, M.4
-
247
-
-
18344415234
-
Down-regulation of transcription factors AP-1, sp-1, and NF-kappaB precedes myocyte differentiation
-
DOI 10.1006/bbrc.1996.1754
-
Lehtinen SK, Rahkila P, Helenius M, Korhonen P, Salminen A (1996) Down-regulation of transcription factors AP-1, Sp-1, and NF-kappa B precedes myocyte differentiation. Biochem Biophys Res Commun 229:36-43 (Pubitemid 27013706)
-
(1996)
Biochemical and Biophysical Research Communications
, vol.229
, Issue.1
, pp. 36-43
-
-
Lehtinen, S.K.1
Rahkila, P.2
Helenius, M.3
Korhonen, P.4
Salminen, A.5
-
248
-
-
33744542153
-
Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein
-
DOI 10.1074/jbc.M511131200
-
Dogra C, Changotra H, Mohan S, Kumar A (2006) Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein. J Biol Chem 281:10327-10336 (Pubitemid 43864571)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.15
, pp. 10327-10336
-
-
Dogra, C.1
Changotra, H.2
Mohan, S.3
Kumar, A.4
-
249
-
-
40849083857
-
IKK/NF-kappaB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis
-
DOI 10.1083/jcb.200707179
-
Bakkar N, Wang J, Ladner KJ, Wang H, Dahlman JM, Carathers M, Acharyya S, Rudnicki MA, Hollenbach AD, Guttridge DC (2008) IKK/NF-kappaB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis. J Cell Biol 180:787-802 (Pubitemid 351397778)
-
(2008)
Journal of Cell Biology
, vol.180
, Issue.4
, pp. 787-802
-
-
Bakkar, N.1
Wang, J.2
Ladner, K.J.3
Wang, H.4
Dahlman, J.M.5
Carathers, M.6
Acharyya, S.7
Rudnicki, M.A.8
Hollenbach, A.D.9
Guttridge, D.C.10
-
250
-
-
0032588186
-
NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1
-
Guttridge DC, Albanese C, Reuther JY, Pestell RG, Baldwin AS Jr (1999) NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol Cell Biol 19:5785-5799 (Pubitemid 29339933)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.8
, pp. 5785-5799
-
-
Guttridge, D.C.1
Albanese, C.2
Reuther, J.Y.3
Pestell, R.G.4
Baldwin Jr., A.S.5
-
251
-
-
58649093547
-
The RelA/p65 subunit of NF-kappaB specifically regulates cyclin D1 protein stability: Implications for cell cycle withdrawal and skeletal myogenesis
-
Dahlman JM, Wang J, Bakkar N, Guttridge DC (2009) The RelA/p65 subunit of NF-kappaB specifically regulates cyclin D1 protein stability: implications for cell cycle withdrawal and skeletal myogenesis. J Cell Biochem 106:42-51
-
(2009)
J Cell Biochem
, vol.106
, pp. 42-51
-
-
Dahlman, J.M.1
Wang, J.2
Bakkar, N.3
Guttridge, D.C.4
-
252
-
-
34250218193
-
NF-kappaB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes
-
DOI 10.1128/MCB.02020-06
-
Wang H, Hertlein E, Bakkar N, Sun H, Acharyya S, Wang J, Carathers M, Davuluri R, Guttridge DC (2007) NF-kappaB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes. Mol Cell Biol 27:4374-4387 (Pubitemid 46906562)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.12
, pp. 4374-4387
-
-
Wang, H.1
Hertlein, E.2
Bakkar, N.3
Sun, H.4
Acharyya, S.5
Wang, J.6
Carathers, M.7
Davuluri, R.8
Guttridge, D.C.9
-
253
-
-
84858793204
-
IKKalpha and alternative NF-kappaB regulate PGC-1beta to promote oxidative muscle metabolism
-
Bakkar N, Ladner K, Canan BD, Liyanarachchi S, Bal NC, Pant M, Periasamy M, Li Q, Janssen PM, Guttridge DC (2012) IKKalpha and alternative NF-kappaB regulate PGC-1beta to promote oxidative muscle metabolism. J Cell Biol 196:497-511
-
(2012)
J Cell Biol
, vol.196
, pp. 497-511
-
-
Bakkar, N.1
Ladner, K.2
Canan, B.D.3
Liyanarachchi, S.4
Bal, N.C.5
Pant, M.6
Periasamy, M.7
Li, Q.8
Janssen, P.M.9
Guttridge, D.C.10
-
254
-
-
25444492611
-
Regulation of IkappaB kinase and NF-kappaB in contracting adult rat skeletal muscle
-
DOI 10.1152/ajpcell.00632.2004
-
Ho RC, Hirshman MF, Li Y, Cai D, Farmer JR, Aschenbach WG, Witczak CA, Shoelson SE, Goodyear LJ (2005) Regulation of IkappaB kinase and NF-kappaB in contracting adult rat skeletal muscle. Am J Physiol Cell Physiol 289:C794-C801 (Pubitemid 41361634)
-
(2005)
American Journal of Physiology - Cell Physiology
, vol.289
, Issue.4
-
-
Ho, R.C.1
Hirshman, M.F.2
Li, Y.3
Cai, D.4
Farmer, J.R.5
Aschenbach, W.G.6
Witczak, C.A.7
Shoelson, S.E.8
Goodyear, L.J.9
-
255
-
-
5044227528
-
Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle
-
DOI 10.1096/fj.04-1846com
-
Ji LL, Gomez-Cabrera MC, Steinhafel N, Vina J (2004) Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle. FASEB J 18:1499-1506 (Pubitemid 39336631)
-
(2004)
FASEB Journal
, vol.18
, Issue.13
, pp. 1499-1506
-
-
Ji, L.L.1
Gomez-Cabrera, M.-C.2
Steinhafel, N.3
Vina, J.4
-
256
-
-
34447632877
-
Exercise, MAPK, and NF-kappaB signaling in skeletal muscle
-
DOI 10.1152/japplphysiol.00085.2007
-
Kramer HF, Goodyear LJ (2007) Exercise, MAPK, and NF-kappaB signaling in skeletal muscle. J Appl Physiol 103:388-395 (Pubitemid 47092316)
-
(2007)
Journal of Applied Physiology
, vol.103
, Issue.1
, pp. 388-395
-
-
Kramer, H.F.1
Goodyear, L.J.2
-
257
-
-
46149126918
-
NF-kappaB signaling in skeletal muscle: Prospects for intervention in muscle diseases
-
Berl
-
Mourkioti F, Rosenthal N (2008) NF-kappaB signaling in skeletal muscle: prospects for intervention in muscle diseases. J Mol Med (Berl) 86:747-759
-
(2008)
J Mol Med
, vol.86
, pp. 747-759
-
-
Mourkioti, F.1
Rosenthal, N.2
-
258
-
-
5444262078
-
IKKbeta/NF-kappaB activation causes severe muscle wasting in mice
-
DOI 10.1016/j.cell.2004.09.027, PII S0092867404009006
-
Cai D, Frantz JD, Tawa NE Jr, Melendez PA, Oh BC, Lidov HG, Hasselgren PO, Frontera WR, Lee J, Glass DJ, Shoelson SE (2004) IKKbeta/NF-kappaB activation causes severe muscle wasting in mice. Cell 119:285-298 (Pubitemid 39360909)
-
(2004)
Cell
, vol.119
, Issue.2
, pp. 285-298
-
-
Cai, D.1
Frantz, J.D.2
Tawa Jr., N.E.3
Melendez, P.A.4
Oh, B.-C.5
Lidov, H.G.W.6
Hasselgren, P.-O.7
Frontera, W.R.8
Lee, J.9
Glass, D.J.10
Shoelson, S.E.11
-
259
-
-
33750595325
-
Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration
-
DOI 10.1172/JCI28721
-
Mourkioti F, Kratsios P, Luedde T, Song YH, Delafontaine P, Adami R, Parente V, Bottinelli R, Pasparakis M, Rosenthal N (2006) Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration. J Clin Invest 116:2945-2954 (Pubitemid 44684479)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.11
, pp. 2945-2954
-
-
Mourkioti, F.1
Kratsios, P.2
Luedde, T.3
Song, Y.-H.4
Delafontaine, P.5
Adami, R.6
Parente, V.7
Bottinelli, R.8
Pasparakis, M.9
Rosenthal, N.10
-
260
-
-
37449022587
-
Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy
-
Serrano AL, Baeza-Raja B, Perdiguero E, Jardi M, Munoz-Canoves P (2008) Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy. Cell Metab 7:33-44
-
(2008)
Cell Metab
, vol.7
, pp. 33-44
-
-
Serrano, A.L.1
Baeza-Raja, B.2
Perdiguero, E.3
Jardi, M.4
Munoz-Canoves, P.5
-
261
-
-
0037726553
-
IL-4 acts as a myoblast recruitment factor during mammalian muscle growth
-
DOI 10.1016/S0092-8674(03)00319-2
-
Horsley V, Jansen KM, Mills ST, Pavlath GK (2003) IL-4 acts as a myoblast recruitment factor duringmammalian muscle growth. Cell 113:483-494 (Pubitemid 36588751)
-
(2003)
Cell
, vol.113
, Issue.4
, pp. 483-494
-
-
Horsley, V.1
Jansen, K.M.2
Mills, S.T.3
Pavlath, G.K.4
-
262
-
-
0346849710
-
Satellite cells attract monocytes and use macrophages as a support to escape apoptosis and enhance muscle growth
-
DOI 10.1083/jcb.200212046
-
Chazaud B, Sonnet C, Lafuste P, Bassez G, Rimaniol AC, Poron F, Authier FJ, Dreyfus PA, Gherardi RK (2003) Satellite cells attract monocytes and use macrophages as a support to escape apoptosis and enhance muscle growth. J Cell Biol 163:1133-1143 (Pubitemid 37541888)
-
(2003)
Journal of Cell Biology
, vol.163
, Issue.5
, pp. 1133-1143
-
-
Chazaud, B.1
Sonnet, C.2
Lafuste, P.3
Bassez, G.4
Rimaniol, A.-C.5
Poron, F.6
Authier, F.-J.7
Dreyfus, P.A.8
Gherardi, R.K.9
-
263
-
-
0027999739
-
Macrophage activation and muscle remodeling at myotendinous junctions after modifications in muscle loading
-
St Pierre BA, Tidball JG (1994) Macrophage activation and muscle remodeling at myotendinous junctions after modifications in muscle loading. Am J Pathol 145:1463-1471 (Pubitemid 24378500)
-
(1994)
American Journal of Pathology
, vol.145
, Issue.6
, pp. 1463-1471
-
-
St., P.B.A.1
Tidball, J.G.2
-
264
-
-
33845785972
-
Macrophages promote muscle membrane repair and muscle fibre growth and regeneration during modified muscle loading in mice in vivo
-
DOI 10.1113/jphysiol.2006.118265
-
Tidball JG, Wehling-Henricks M (2007) Macrophages promote muscle membrane repair and muscle fibre growth and regeneration during modified muscle loading in mice in vivo. J Physiol 578:327-336 (Pubitemid 44971129)
-
(2007)
Journal of Physiology
, vol.578
, Issue.1
, pp. 327-336
-
-
Tidball, J.G.1
Wehling-Henricks, M.2
-
265
-
-
81455154927
-
IFN-gamma promotes muscle damage in the mdx mouse model of Duchenne muscular dystrophy by suppressing M2 macrophage activation and inhibiting muscle cell proliferation
-
Villalta SA, Deng B, Rinaldi C, Wehling-Henricks M, Tidball JG (2011) IFN-gamma promotes muscle damage in the mdx mouse model of Duchenne muscular dystrophy by suppressing M2 macrophage activation and inhibiting muscle cell proliferation. J Immunol 187:5419-5428
-
(2011)
J Immunol
, vol.187
, pp. 5419-5428
-
-
Villalta, S.A.1
Deng, B.2
Rinaldi, C.3
Wehling-Henricks, M.4
Tidball, J.G.5
-
266
-
-
78751682676
-
Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype
-
Villalta SA, Rinaldi C, Deng B, Liu G, Fedor B, Tidball JG (2010) Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype. Hum Mol Genet 20:790-805
-
(2010)
Hum Mol Genet
, vol.20
, pp. 790-805
-
-
Villalta, S.A.1
Rinaldi, C.2
Deng, B.3
Liu, G.4
Fedor, B.5
Tidball, J.G.6
-
267
-
-
0034668926
-
Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6
-
Steensberg A, van Hall G, Osada T, Sacchetti M, Saltin B, Klarlund Pedersen B (2000) Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6. J Physiol 529(Pt 1):237-242
-
(2000)
J Physiol
, vol.529
, Issue.PART 1
, pp. 237-242
-
-
Steensberg, A.1
Van Hall, G.2
Osada, T.3
Sacchetti, M.4
Saltin, B.5
Klarlund Pedersen, B.6
-
268
-
-
55949119252
-
Muscle as an endocrine organ: Focus on muscle-derived interleukin-6
-
Pedersen BK, Febbraio MA (2008) Muscle as an endocrine organ: focus on muscle-derived interleukin-6. Physiol Rev 88:1379-1406
-
(2008)
Physiol Rev
, vol.88
, pp. 1379-1406
-
-
Pedersen, B.K.1
Febbraio, M.A.2
-
269
-
-
33750859187
-
Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase
-
DOI 10.2337/db05-1404
-
Carey AL, Steinberg GR, Macaulay SL, Thomas WG, Holmes AG, Ramm G, Prelovsek O, Hohnen-Behrens C, Watt MJ, James DE, Kemp BE, Pedersen BK, Febbraio MA (2006) Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase. Diabetes 55:2688-2697 (Pubitemid 44923666)
-
(2006)
Diabetes
, vol.55
, Issue.10
, pp. 2688-2697
-
-
Carey, A.L.1
Steinberg, G.R.2
Macaulay, S.L.3
Thomas, W.G.4
Holmes, A.G.5
Ramm, G.6
Prelovsek, O.7
Hohnen-Behrens, C.8
Watt, M.J.9
James, D.E.10
Kemp, B.E.11
Pedersen, B.K.12
Febbraio, M.A.13
-
270
-
-
0036152683
-
Interleukin-6-deficient mice develop mature-onset obesity
-
DOI 10.1038/nm0102-75
-
Wallenius V, Wallenius K, Ahren B, Rudling M, Carlsten H, Dickson SL, Ohlsson C, Jansson JO (2002) Interleukin-6-deficient mice develop mature-onset obesity. Nat Med 8:75-79 (Pubitemid 34101732)
-
(2002)
Nature Medicine
, vol.8
, Issue.1
, pp. 75-79
-
-
Wallenius, V.1
Wallenius, K.2
Ahren, B.3
Rudling, M.4
Carlsten, H.5
Dickson, S.L.6
Ohlsson, C.7
Jansson, J.-O.8
-
271
-
-
21744456561
-
Interleukin-6 receptor expression in contracting human skeletal muscle: Regulating role of IL-6
-
DOI 10.1096/fj.04-3278fje
-
Keller P, Penkowa M, Keller C, Steensberg A, Fischer CP, Giralt M, Hidalgo J, Pedersen BK (2005) Interleukin-6 receptor expression in contracting human skeletal muscle: regulating role of IL-6. FASEB J 19:1181-1183 (Pubitemid 40946458)
-
(2005)
FASEB Journal
, vol.19
, Issue.9
, pp. 1181-1183
-
-
Keller, P.1
Penkowa, M.2
Keller, C.3
Steensberg, A.4
Fischer, C.P.5
Giralt, M.6
Hidalgo, J.7
Pedersen, B.K.8
-
272
-
-
34547626210
-
Immune function in sport and exercise
-
Gleeson M (2007) Immune function in sport and exercise. J Appl Physiol 103:693-699
-
(2007)
J Appl Physiol
, vol.103
, pp. 693-699
-
-
Gleeson, M.1
-
273
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
DOI 10.1056/NEJMoa012512
-
Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393-403 (Pubitemid 34437694)
-
(2002)
New England Journal of Medicine
, vol.346
, Issue.6
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
Hamman, R.F.4
Lachin, J.M.5
Walker, E.A.6
Nathan, D.M.7
-
274
-
-
0028341292
-
Exercise training and nutritional supplementation for physical frailty in very elderly people
-
DOI 10.1056/NEJM199406233302501
-
Fiatarone MA, O'Neill EF, Ryan ND, Clements KM, Solares GR, Nelson ME, Roberts SB, Kehayias JJ, Lipsitz LA, Evans WJ (1994) Exercise training and nutritional supplementation for physical frailty in very elderly people. N Engl J Med 330:1769-1775 (Pubitemid 24177611)
-
(1994)
New England Journal of Medicine
, vol.330
, Issue.25
, pp. 1769-1775
-
-
Fiatarone, M.A.1
O'Neill, E.F.2
Ryan, N.D.3
Clements, K.M.4
Solares, G.R.5
Nelson, M.E.6
Roberts, S.B.7
Kehayias, J.J.8
Lipsitz, L.A.9
Evans, W.J.10
-
275
-
-
0012849885
-
Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease
-
DOI 10.1016/S0306-4522(03)00096-4
-
Tillerson JL, Caudle WM, Reveron ME, Miller GW (2003) Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease. Neuroscience 119:899-911 (Pubitemid 36694814)
-
(2003)
Neuroscience
, vol.119
, Issue.3
, pp. 899-911
-
-
Tillerson, J.L.1
Caudle, W.M.2
Reveron, M.E.3
Miller, G.W.4
-
276
-
-
0041846867
-
IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans
-
Steensberg A, Fischer CP, Keller C, Moller K, Pedersen BK (2003) IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans. Am J Physiol Endocrinol Metab 285:E433-E437 (Pubitemid 36899719)
-
(2003)
American Journal of Physiology - Endocrinology and Metabolism
, vol.285
, Issue.2
-
-
Steensberg, A.1
Fischer, C.P.2
Keller, C.3
Moller, K.4
Pedersen, B.K.5
-
277
-
-
0038322493
-
Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans
-
Starkie R, Ostrowski SR, Jauffred S, Febbraio M, Pedersen BK (2003) Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans. FASEB J 17:884-886
-
(2003)
FASEB J
, vol.17
, pp. 884-886
-
-
Starkie, R.1
Ostrowski, S.R.2
Jauffred, S.3
Febbraio, M.4
Pedersen, B.K.5
-
278
-
-
15844366621
-
The physiological regulation of toll-like receptor expression and function in humans
-
DOI 10.1113/jphysiol.2004.081224
-
Lancaster GI, Khan Q, Drysdale P, Wallace F, Jeukendrup AE, Drayson MT, Gleeson M (2005) The physiological regulation of toll-like receptor expression and function in humans. J Physiol 563:945-955 (Pubitemid 40425607)
-
(2005)
Journal of Physiology
, vol.563
, Issue.3
, pp. 945-955
-
-
Lancaster, G.I.1
Khan, Q.2
Drysdale, P.3
Wallace, F.4
Jeukendrup, A.E.5
Drayson, M.T.6
Gleeson, M.7
-
279
-
-
25444493937
-
Suppression of estrogen-related receptor alpha and medium-chain acyl-coenzyme A dehydrogenase in the acute-phase response
-
DOI 10.1194/jlr.M500217-JLR200
-
Kim MS, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C (2005) Suppression of estrogen-related receptor alpha and medium-chain acyl-coenzyme A dehydrogenase in the acute-phase response. J Lipid Res 46:2282-2288 (Pubitemid 41377480)
-
(2005)
Journal of Lipid Research
, vol.46
, Issue.10
, pp. 2282-2288
-
-
Kim, M.S.1
Shigenaga, J.K.2
Moser, A.H.3
Feingold, K.R.4
Grunfeld, C.5
-
280
-
-
0942287345
-
Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response
-
Feingold K, Kim MS, Shigenaga J, Moser A, Grunfeld C (2004) Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response. Am J Physiol Endocrinol Metab 286:E201-E207 (Pubitemid 38140310)
-
(2004)
American Journal of Physiology - Endocrinology and Metabolism
, vol.286
, Issue.2
-
-
Feingold, K.1
Kim, M.S.2
Shigenaga, J.3
Moser, A.4
Grunfeld, C.5
-
281
-
-
24344473701
-
Atorvastatin prevents peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) downregulation in lipopolysaccharide-stimulated H9c2 cells
-
DOI 10.1016/j.bbalip.2005.08.001, PII S1388198105001721
-
Planavila A, Sanchez RM, Merlos M, Laguna JC, Vazquez-Carrera M (2005) Atorvastatin prevents peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) downregulation in lipopolysaccharide-stimulated H9c2 cells. Biochim Biophys Acta 1736:120-127 (Pubitemid 41262569)
-
(2005)
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, vol.1736
, Issue.2
, pp. 120-127
-
-
Planavila, A.1
Sanchez, R.M.2
Merlos, M.3
Laguna, J.C.4
Vazquez-Carrera, M.5
-
282
-
-
60149110303
-
TNF-alpha reduces PGC-1alpha expression through NFkappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model
-
Palomer X, Alvarez-Guardia D, Rodriguez-Calvo R, Coll T, Laguna JC, Davidson MM, Chan TO, Feldman AM, Vazquez-Carrera M (2009) TNF-alpha reduces PGC-1alpha expression through NFkappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model. Cardiovasc Res 81:703-712
-
(2009)
Cardiovasc Res
, vol.81
, pp. 703-712
-
-
Palomer, X.1
Alvarez-Guardia, D.2
Rodriguez-Calvo, R.3
Coll, T.4
Laguna, J.C.5
Davidson, M.M.6
Chan, T.O.7
Feldman, A.M.8
Vazquez-Carrera, M.9
-
283
-
-
80053402552
-
PGC-1alpha promotes recovery after acute kidney injury during systemic inflammation inmice
-
Tran M, Tam D, Bardia A, Bhasin M, Rowe GC, Kher A, Zsengeller ZK, Akhavan-Sharif MR, Khankin EV, Saintgeniez M, David S, Burstein D, Karumanchi SA, Stillman IE, Arany Z, Parikh SM (2011) PGC-1alpha promotes recovery after acute kidney injury during systemic inflammation inmice. J Clin Invest 121:4003-4014
-
(2011)
J Clin Invest
, vol.121
, pp. 4003-4014
-
-
Tran, M.1
Tam, D.2
Bardia, A.3
Bhasin, M.4
Rowe, G.C.5
Kher, A.6
Zsengeller, Z.K.7
Akhavan-Sharif, M.R.8
Khankin, E.V.9
Saintgeniez, M.10
David, S.11
Burstein, D.12
Karumanchi, S.A.13
Stillman, I.E.14
Arany, Z.15
Parikh, S.M.16
-
284
-
-
80053151124
-
A toll-like receptor 2 pathway regulates the Ppargc1a/b metabolic co-activators in mice with staphylococcal aureus sepsis
-
Sweeney TE, Suliman HB, Hollingsworth JW, Welty-Wolf KE, Piantadosi CA (2011) A toll-like receptor 2 pathway regulates the Ppargc1a/b metabolic co-activators in mice with staphylococcal aureus sepsis. PLoS One 6:e25249
-
(2011)
PLoS One
, vol.6
-
-
Sweeney, T.E.1
Suliman, H.B.2
Hollingsworth, J.W.3
Welty-Wolf, K.E.4
Piantadosi, C.A.5
-
285
-
-
77957562997
-
Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1beta in skeletal muscle
-
Menconi MJ, Arany ZP, Alamdari N, Aversa Z, Gonnella P, O'Neal P, Smith IJ, Tizio S, Hasselgren PO (2010) Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1beta in skeletal muscle. Am J Physiol Endocrinol Metab 299:E533-E543
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
-
-
Menconi, M.J.1
Arany, Z.P.2
Alamdari, N.3
Aversa, Z.4
Gonnella, P.5
O'Neal, P.6
Smith, I.J.7
Tizio, S.8
Hasselgren, P.O.9
-
286
-
-
70350370459
-
Infection decreases fatty acid oxidation and nuclear hormone receptors in the diaphragm
-
Feingold KR, Moser A, Patzek SM, Shigenaga JK, Grunfeld C (2009) Infection decreases fatty acid oxidation and nuclear hormone receptors in the diaphragm. J Lipid Res 50:2055-2063
-
(2009)
J Lipid Res
, vol.50
, pp. 2055-2063
-
-
Feingold, K.R.1
Moser, A.2
Patzek, S.M.3
Shigenaga, J.K.4
Grunfeld, C.5
-
287
-
-
0033862763
-
Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics
-
Yu XX, Barger JL, Boyer BB, Brand MD, Pan G, Adams SH (2000) Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics. Am J Physiol Endocrinol Metab 279:E433-E446
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
-
-
Yu, X.X.1
Barger, J.L.2
Boyer, B.B.3
Brand, M.D.4
Pan, G.5
Adams, S.H.6
-
288
-
-
84877351666
-
Regulation of skeletal muscle oxidative phenotype by classical NF-kappaB signalling
-
Remels AH, Gosker HR, Bakker J, Guttridge DC, Schols AM, Langen RC (2013) Regulation of skeletal muscle oxidative phenotype by classical NF-kappaB signalling. Biochim Biophys Acta 1832:1313-1325
-
(2013)
Biochim Biophys Acta
, vol.1832
, pp. 1313-1325
-
-
Remels, A.H.1
Gosker, H.R.2
Bakker, J.3
Guttridge, D.C.4
Schols, A.M.5
Langen, R.C.6
-
289
-
-
33750877988
-
Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation
-
DOI 10.2337/db05-1494
-
Coll T, Jove M, Rodriguez-Calvo R, Eyre E, Palomer X, Sanchez RM, Merlos M, Laguna JC, Vazquez-Carrera M (2006) Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation. Diabetes 55:2779-2787 (Pubitemid 44923677)
-
(2006)
Diabetes
, vol.55
, Issue.10
, pp. 2779-2787
-
-
Coll, T.1
Jove, M.2
Rodriguez-Calvo, R.3
Eyre, E.4
Palomer, X.5
Sanchez, R.M.6
Merlos, M.7
Laguna, J.C.8
Vazquez-Carrera, M.9
-
290
-
-
42649104789
-
PGC-1alpha inhibits oleic acid induced proliferation and migration of rat vascular smooth muscle cells
-
Zhang Y, Liu C, Zhu L, Jiang X, Chen X, Qi X, Liang X, Jin S, Zhang P, Li Q, Wang D, Liu X, Zeng K, Zhang J, Xiang Y, Zhang CY (2007) PGC-1alpha inhibits oleic acid induced proliferation and migration of rat vascular smooth muscle cells. PLoS One 2:e1137
-
(2007)
PLoS One
, vol.2
-
-
Zhang, Y.1
Liu, C.2
Zhu, L.3
Jiang, X.4
Chen, X.5
Qi, X.6
Liang, X.7
Jin, S.8
Zhang, P.9
Li, Q.10
Wang, D.11
Liu, X.12
Zeng, K.13
Zhang, J.14
Xiang, Y.15
Zhang, C.Y.16
-
291
-
-
78649743322
-
TNF-alpha impairs regulation of muscle oxidative phenotype: Implications for cachexia?
-
Remels AH, Gosker HR, Schrauwen P, Hommelberg PP, Sliwinski P, Polkey M, Galdiz J, Wouters EF, Langen RC, Schols AM (2010) TNF-alpha impairs regulation of muscle oxidative phenotype: implications for cachexia? FASEB J : Off Publ Fed Am Soc Exp Biol 24:5052-5062
-
(2010)
FASEB J: Off Publ Fed Am Soc Exp Biol
, vol.24
, pp. 5052-5062
-
-
Remels, A.H.1
Gosker, H.R.2
Schrauwen, P.3
Hommelberg, P.P.4
Sliwinski, P.5
Polkey, M.6
Galdiz, J.7
Wouters, E.F.8
Langen, R.C.9
Schols, A.M.10
-
292
-
-
73349101897
-
TNF-alpha-mediated reduction in PGC-1alpha may impair skeletal muscle function after cigarette smoke exposure
-
Tang K, Wagner PD, Breen EC (2010) TNF-alpha-mediated reduction in PGC-1alpha may impair skeletal muscle function after cigarette smoke exposure. J Cell Physiol 222:320-327
-
(2010)
J Cell Physiol
, vol.222
, pp. 320-327
-
-
Tang, K.1
Wagner, P.D.2
Breen, E.C.3
-
293
-
-
34547562005
-
Peroxisome proliferator-activated receptor expression is reduced in skeletal muscle in COPD
-
DOI 10.1183/09031936.00144106
-
Remels AH, Schrauwen P, Broekhuizen R, Willems J, Kersten S, Gosker HR, Schols AM (2007) Peroxisome proliferator-activated receptor expression is reduced in skeletal muscle in COPD. Eur Respir J : Off J Eur Soc Clin Respir Physiol 30:245-252 (Pubitemid 47194177)
-
(2007)
European Respiratory Journal
, vol.30
, Issue.2
, pp. 245-252
-
-
Remels, A.H.1
Schrauwen, P.2
Broekhuizen, R.3
Willems, J.4
Kersten, S.5
Gosker, H.R.6
Schols, A.M.7
-
294
-
-
84873880480
-
The peroxisome proliferator-activated receptor gamma coactivator 1alpha/beta (PGC-1) coactivators repress the transcriptional activity of NF-kappaB in skeletal muscle cells
-
Eisele PS, Salatino S, Sobek J, Hottiger MO, Handschin C (2013) The peroxisome proliferator-activated receptor gamma coactivator 1alpha/beta (PGC-1) coactivators repress the transcriptional activity of NF-kappaB in skeletal muscle cells. J Biol Chem 288:6589
-
(2013)
J Biol Chem
, vol.288
, pp. 6589
-
-
Eisele, P.S.1
Salatino, S.2
Sobek, J.3
Hottiger, M.O.4
Handschin, C.5
-
295
-
-
33846463967
-
Effects of PGC-1alpha on TNF-alpha-induced MCP-1 and VCAM-1 expression and NF-kappaB activation in human aortic smooth muscle and endothelial cells
-
DOI 10.1089/ars.2006.1456
-
Kim HJ, Park KG, Yoo EK, Kim YH, Kim YN, Kim HS, Kim HT, Park JY, Lee KU, Jang WG, Kim JG, Kim BW, Lee IK (2007) Effects of PGC-1alpha on TNF-alpha-induced MCP-1 and VCAM-1 expression and NF-kappaB activation in human aortic smooth muscle and endothelial cells. Antioxid Redox Signal 9:301-307 (Pubitemid 46150964)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.3
, pp. 301-307
-
-
Kim, H.-J.1
Park, K.-G.2
Yoo, E.-K.3
Kim, Y.-H.4
Kim, Y.-N.5
Kim, H.-S.6
Kim, H.T.7
Park, J.-Y.8
Lee, K.-U.9
Jang, W.G.10
Kim, J.-G.11
Kim, B.-W.12
Lee, I.-K.13
-
296
-
-
84857574974
-
Skeletal muscle PGC-1alpha is required for maintaining an acute LPS-induced TNFalpha response
-
Olesen J, Larsson S, Iversen N, Yousafzai S, Hellsten Y, Pilegaard H (2012) Skeletal muscle PGC-1alpha is required for maintaining an acute LPS-induced TNFalpha response. PLoS One 7:e32222
-
(2012)
PLoS One
, vol.7
-
-
Olesen, J.1
Larsson, S.2
Iversen, N.3
Yousafzai, S.4
Hellsten, Y.5
Pilegaard, H.6
-
297
-
-
34547643550
-
Nuclear receptor ERRalpha and coactivator PGC-1beta are effectors of IFN-gamma-induced host defense
-
DOI 10.1101/gad.1553007
-
Sonoda J, Laganiere J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguere V, Evans RM (2007) Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense. Genes Dev 21:1909-1920 (Pubitemid 47204930)
-
(2007)
Genes and Development
, vol.21
, Issue.15
, pp. 1909-1920
-
-
Sonoda, J.1
Laganiere, J.2
Mehl, I.R.3
Barish, G.D.4
Chong, L.-W.5
Li, X.6
Scheffler, I.E.7
Mock, D.C.8
Bataille, A.R.9
Robert, F.10
Lee, C.-H.11
Giguere, V.12
Evans, R.M.13
-
298
-
-
77951822653
-
Dynamic, M2-like remodeling phenotypes of CD11c+adipose tissue macrophages during high-fat diet-induced obesity in mice
-
Shaul ME, Bennett G, Strissel KJ, Greenberg AS, Obin MS (2010) Dynamic, M2-like remodeling phenotypes of CD11c+adipose tissue macrophages during high-fat diet-induced obesity in mice. Diabetes 59:1171-1181
-
(2010)
Diabetes
, vol.59
, pp. 1171-1181
-
-
Shaul, M.E.1
Bennett, G.2
Strissel, K.J.3
Greenberg, A.S.4
Obin, M.S.5
-
299
-
-
72149111665
-
IRAK-1 contributes to lipopolysaccharide-induced reactive oxygen species generation in macrophages by inducing NOX-1 transcription and Rac1 activation and suppressing the expression of antioxidative enzymes
-
Maitra U, Singh N, Gan L, Ringwood L, Li L (2009) IRAK-1 contributes to lipopolysaccharide-induced reactive oxygen species generation in macrophages by inducing NOX-1 transcription and Rac1 activation and suppressing the expression of antioxidative enzymes. J Biol Chem 284:35403-35411
-
(2009)
J Biol Chem
, vol.284
, pp. 35403-35411
-
-
Maitra, U.1
Singh, N.2
Gan, L.3
Ringwood, L.4
Li, L.5
-
300
-
-
0033104946
-
Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma-induced genes by suppressing tyrosine phosphorylation of STAT1
-
Ito S, Ansari P, Sakatsume M, Dickensheets H, Vazquez N, Donnelly RP, Larner AC, Finbloom DS (1999) Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma-induced genes by suppressing tyrosine phosphorylation of STAT1. Blood 93:1456-1463 (Pubitemid 29102470)
-
(1999)
Blood
, vol.93
, Issue.5
, pp. 1456-1463
-
-
Ito, S.1
Ansari, P.2
Sakatsume, M.3
Dickensheets, H.4
Vazquez, N.5
Donnelly, R.P.6
Larner, A.C.7
Finbloom, D.S.8
-
301
-
-
70349275277
-
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB
-
Porta C, Rimoldi M, Raes G, Brys L, Ghezzi P, Di Liberto D, Dieli F, Ghisletti S, Natoli G, De Baetselier P, Mantovani A, Sica A (2009) Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB. Proc Natl Acad Sci U S A 106:14978-14983
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14978-14983
-
-
Porta, C.1
Rimoldi, M.2
Raes, G.3
Brys, L.4
Ghezzi, P.5
Di Liberto, D.6
Dieli, F.7
Ghisletti, S.8
Natoli, G.9
De Baetselier, P.10
Mantovani, A.11
Sica, A.12
-
302
-
-
79960021457
-
Kruppel-like factor 4 regulates macrophage polarization
-
Liao X, Sharma N, Kapadia F, Zhou G, Lu Y, Hong H, Paruchuri K, Mahabeleshwar GH, Dalmas E, Venteclef N, Flask CA, Kim J, Doreian BW, Lu KQ, Kaestner KH, Hamik A, Clement K, Jain MK (2011) Kruppel-like factor 4 regulates macrophage polarization. J Clin Invest 121:2736-2749
-
(2011)
J Clin Invest
, vol.121
, pp. 2736-2749
-
-
Liao, X.1
Sharma, N.2
Kapadia, F.3
Zhou, G.4
Lu, Y.5
Hong, H.6
Paruchuri, K.7
Mahabeleshwar, G.H.8
Dalmas, E.9
Venteclef, N.10
Flask, C.A.11
Kim, J.12
Doreian, B.W.13
Lu, K.Q.14
Kaestner, K.H.15
Hamik, A.16
Clement, K.17
Jain, M.K.18
-
303
-
-
79956305398
-
The myeloid transcription factor KLF2 regulates the host response to polymicrobial infection and endotoxic shock
-
Mahabeleshwar GH, Kawanami D, Sharma N, Takami Y, Zhou G, Shi H, Nayak L, Jeyaraj D, Grealy R, White M, McManus R, Ryan T, Leahy P, Lin Z, Haldar SM, Atkins GB, Wong HR, Lingrel JB, Jain MK (2011) The myeloid transcription factor KLF2 regulates the host response to polymicrobial infection and endotoxic shock. Immunity 34:715-728
-
(2011)
Immunity
, vol.34
, pp. 715-728
-
-
Mahabeleshwar, G.H.1
Kawanami, D.2
Sharma, N.3
Takami, Y.4
Zhou, G.5
Shi, H.6
Nayak, L.7
Jeyaraj, D.8
Grealy, R.9
White, M.10
McManus, R.11
Ryan, T.12
Leahy, P.13
Lin, Z.14
Haldar, S.M.15
Atkins, G.B.16
Wong, H.R.17
Lingrel, J.B.18
Jain, M.K.19
-
304
-
-
44349161098
-
Alternative M2 Activation of Kupffer Cells by PPARdelta Ameliorates Obesity-Induced Insulin Resistance
-
DOI 10.1016/j.cmet.2008.04.003, PII S1550413108001137
-
Odegaard JI, Ricardo-Gonzalez RR, Red Eagle A, Vats D, Morel CR, Goforth MH, Subramanian V, Mukundan L, Ferrante AW, Chawla A (2008) Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance. Cell Metab 7:496-507 (Pubitemid 351729205)
-
(2008)
Cell Metabolism
, vol.7
, Issue.6
, pp. 496-507
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Red, E.A.3
Vats, D.4
Morel, C.R.5
Goforth, M.H.6
Subramanian, V.7
Mukundan, L.8
Ferrante, A.W.9
Chawla, A.10
-
305
-
-
77955392757
-
Co-regulation of nuclear respiratory factor-1 by NFkappaB and CREB links LPS-induced inflammation to mitochondrial biogenesis
-
Suliman HB, Sweeney TE, Withers CM, Piantadosi CA (2010) Co-regulation of nuclear respiratory factor-1 by NFkappaB and CREB links LPS-induced inflammation to mitochondrial biogenesis. J Cell Sci 123:2565-2575
-
(2010)
J Cell Sci
, vol.123
, pp. 2565-2575
-
-
Suliman, H.B.1
Sweeney, T.E.2
Withers, C.M.3
Piantadosi, C.A.4
-
306
-
-
80053539605
-
NF-kappaB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration
-
Mauro C, Leow SC, Anso E, Rocha S, Thotakura AK, Tornatore L, Moretti M, De Smaele E, Beg AA, Tergaonkar V, Chandel NS, Franzoso G (2011) NF-kappaB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration. Nat Cell Biol 13:1272-1279
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1272-1279
-
-
Mauro, C.1
Leow, S.C.2
Anso, E.3
Rocha, S.4
Thotakura, A.K.5
Tornatore, L.6
Moretti, M.7
De Smaele, E.8
Beg, A.A.9
Tergaonkar, V.10
Chandel, N.S.11
Franzoso, G.12
-
307
-
-
79955542142
-
Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression
-
Piantadosi CA, Withers CM, Bartz RR, MacGarvey NC, Fu P, Sweeney TE, Welty-Wolf KE, Suliman HB (2011) Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression. J Biol Chem 286:16374-16385
-
(2011)
J Biol Chem
, vol.286
, pp. 16374-16385
-
-
Piantadosi, C.A.1
Withers, C.M.2
Bartz, R.R.3
MacGarvey, N.C.4
Fu, P.5
Sweeney, T.E.6
Welty-Wolf, K.E.7
Suliman, H.B.8
-
308
-
-
84855826059
-
Energy-sensing factors coactivator peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha) and AMP-activated protein kinase control expression of inflammatory mediators in liver: Induction of interleukin 1 receptor antagonist
-
Buler M, Aatsinki SM, Skoumal R, Komka Z, Toth M, Kerkela R, Georgiadi A, Kersten S, Hakkola J (2012) Energy-sensing factors coactivator peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha) and AMP-activated protein kinase control expression of inflammatory mediators in liver: induction of interleukin 1 receptor antagonist. J Biol Chem 287:1847-1860
-
(2012)
J Biol Chem
, vol.287
, pp. 1847-1860
-
-
Buler, M.1
Aatsinki, S.M.2
Skoumal, R.3
Komka, Z.4
Toth, M.5
Kerkela, R.6
Georgiadi, A.7
Kersten, S.8
Hakkola, J.9
-
309
-
-
4444280899
-
Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease
-
DOI 10.1053/j.gastro.2004.06.049, PII S0016508504011813
-
Bassaganya-Riera J, Reynolds K, Martino-Catt S, Cui Y, Hennighausen L, Gonzalez F, Rohrer J, Benninghoff AU, Hontecillas R (2004) Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease. Gastroenterol 127:777-791 (Pubitemid 39208411)
-
(2004)
Gastroenterology
, vol.127
, Issue.3
, pp. 777-791
-
-
Bassaganya-Riera, J.1
Reynolds, K.2
Martino-Catt, S.3
Cui, Y.4
Hennighausen, L.5
Gonzalez, F.6
Rohrer, J.7
Benninghoff, A.U.8
Hontecillas, R.9
-
310
-
-
39649120375
-
Inhibition of adhesive interaction between multiple myeloma and bone marrow stromal cells by PPARgamma cross talk with NF-kappaB and C/EBP
-
DOI 10.1182/blood-2006-07-038026
-
Wang LH, Yang XY, Zhang X, Farrar WL (2007) Inhibition of adhesive interaction between multiple myeloma and bone marrow stromal cells by PPARgamma cross talk with NF-kappaB and C/EBP. Blood 110:4373-4384 (Pubitemid 351377804)
-
(2007)
Blood
, vol.110
, Issue.13
, pp. 4373-4384
-
-
Li, H.W.1
Xiao, Y.Y.2
Zhang, X.3
Farrar, W.L.4
-
311
-
-
74049092099
-
The role of proliferator-activated receptor gamma coactivator-1alpha in the fatty-acid-dependent transcriptional control of interleukin-10 in hepatic cells of rodents
-
Morari J, Torsoni AS, Anhe GF, Roman EA, Cintra DE, Ward LS, Bordin S, Velloso LA (2010) The role of proliferator-activated receptor gamma coactivator-1alpha in the fatty-acid-dependent transcriptional control of interleukin-10 in hepatic cells of rodents. Metab: Clin Exp 59:215-223
-
(2010)
Metab: Clin Exp
, vol.59
, pp. 215-223
-
-
Morari, J.1
Torsoni, A.S.2
Anhe, G.F.3
Roman, E.A.4
Cintra, D.E.5
Ward, L.S.6
Bordin, S.7
Velloso, L.A.8
-
312
-
-
77954775834
-
The p65 subunit of NF-kappaB binds to PGC-1alpha, linking inflammation and metabolic disturbances in cardiac cells
-
Alvarez-Guardia D, Palomer X, Coll T, Davidson MM, Chan TO, Feldman AM, Laguna JC, Vazquez-Carrera M (2010) The p65 subunit of NF-kappaB binds to PGC-1alpha, linking inflammation and metabolic disturbances in cardiac cells. Cardiovasc Res 87:449-458
-
(2010)
Cardiovasc Res
, vol.87
, pp. 449-458
-
-
Alvarez-Guardia, D.1
Palomer, X.2
Coll, T.3
Davidson, M.M.4
Chan, T.O.5
Feldman, A.M.6
Laguna, J.C.7
Vazquez-Carrera, M.8
-
313
-
-
65649148341
-
Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity
-
Liang H, Balas B, Tantiwong P, Dube J, Goodpaster BH, O'Doherty RM, DeFronzo RA, Richardson A, Musi N, Ward WF (2009) Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity. Am J Physiol Endocrinol Metab 296:E945-E954
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
-
-
Liang, H.1
Balas, B.2
Tantiwong, P.3
Dube, J.4
Goodpaster, B.H.5
O'Doherty, R.M.6
DeFronzo, R.A.7
Richardson, A.8
Musi, N.9
Ward, W.F.10
-
314
-
-
67651236631
-
Bcl3 interacts cooperatively with peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator 1alpha to coactivate nuclear receptors estrogen-related receptor alpha and PPARalpha
-
Yang J, Williams RS, Kelly DP (2009) Bcl3 interacts cooperatively with peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator 1alpha to coactivate nuclear receptors estrogen-related receptor alpha and PPARalpha. Mol Cell Biol 29:4091-4102
-
(2009)
Mol Cell Biol
, vol.29
, pp. 4091-4102
-
-
Yang, J.1
Williams, R.S.2
Kelly, D.P.3
-
315
-
-
84878833173
-
Expression of anti-inflammatory macrophage genes within skeletal muscle correlates with insulin sensitivity in human obesity and type 2 diabetes
-
Fink LN, Oberbach A, Costford SR, Chan KL, Sams A, Bluher M, Klip A (2013) Expression of anti-inflammatory macrophage genes within skeletal muscle correlates with insulin sensitivity in human obesity and type 2 diabetes. Diabetologia 56:1623-1628
-
(2013)
Diabetologia
, vol.56
, pp. 1623-1628
-
-
Fink, L.N.1
Oberbach, A.2
Costford, S.R.3
Chan, K.L.4
Sams, A.5
Bluher, M.6
Klip, A.7
-
316
-
-
84895820360
-
Pro-inflammatory macrophages increase in skeletal muscle of high fat-Fed mice and correlate with metabolic risk markers in humans
-
doi:10.1002/oby.20615
-
Fink LN, Costford SR, Lee YS, Jensen TE, Bilan PJ, Oberbach A, Bluher M, Olefsky JM, Sams A, Klip A (2013) Pro-inflammatory macrophages increase in skeletal muscle of high fat-Fed mice and correlate with metabolic risk markers in humans. Obesity doi:10.1002/oby.20615
-
(2013)
Obesity
-
-
Fink, L.N.1
Costford, S.R.2
Lee, Y.S.3
Jensen, T.E.4
Bilan, P.J.5
Oberbach, A.6
Bluher, M.7
Olefsky, J.M.8
Sams, A.9
Klip, A.10
-
317
-
-
84887439235
-
Exercise-induced enhancement of insulin sensitivity is associated with accumulation of M2-polarized macrophages in mouse skeletal muscle
-
doi:10.1016/j.bbrc.2013.10.005
-
Ikeda SI, Tamura Y, Kakehi S, Takeno K, Kawaguchi M, Watanabe T, Sato F, Ogihara T, Kanazawa A, Fujitani Y, Kawamori R, Watada H (2013) Exercise-induced enhancement of insulin sensitivity is associated with accumulation of M2-polarized macrophages in mouse skeletal muscle. Biochem Biophys Res Commun doi:10.1016/j.bbrc.2013.10.005
-
(2013)
Biochem Biophys Res Commun
-
-
Ikeda, S.I.1
Tamura, Y.2
Kakehi, S.3
Takeno, K.4
Kawaguchi, M.5
Watanabe, T.6
Sato, F.7
Ogihara, T.8
Kanazawa, A.9
Fujitani, Y.10
Kawamori, R.11
Watada, H.12
-
318
-
-
34247860695
-
Characterization of the transactivation domain in the peroxisome- proliferator-activated receptor gamma co-activator (PGC-1)
-
DOI 10.1042/BJ20061526
-
Sadana P, Park EA (2007) Characterization of the transactivation domain in the peroxisome-proliferator-activated receptor gamma co-activator (PGC-1). Biochem J 403:511-518 (Pubitemid 46706979)
-
(2007)
Biochemical Journal
, vol.403
, Issue.3
, pp. 511-518
-
-
Sadana, P.1
Park, E.A.2
|