메뉴 건너뛰기




Volumn 8, Issue 1, 2002, Pages 75-79

Interleukin-6-deficient mice develop mature-onset obesity

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOBESITY AGENT; CYTOKINE; INTERLEUKIN 6;

EID: 0036152683     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0102-75     Document Type: Article
Times cited : (1071)

References (36)
  • 4
    • 0028328436 scopus 로고
    • Impaired immune and acute-phase responses in interleukin-6-deficient mice
    • (1994) Nature , vol.368 , pp. 339-342
    • Kopf, M.1
  • 10
    • 0032523908 scopus 로고    scopus 로고
    • The expressions of mRNAs for interleukin-6 (IL-6) and the IL-6 receptor (IL-6R) in the rat hypothalamus and midbrain during restraint stress
    • (1998) Life Sci. , vol.62 , pp. 2315-2320
    • Shizuya, K.1
  • 11
    • 18144435991 scopus 로고    scopus 로고
    • Immune and inflammatory responses in the CNS: Modulation by astrocytes
    • (1998) Toxicol. Lett. , vol.102-103 , pp. 283-287
    • Aschner, M.1
  • 12
  • 13
    • 0026669452 scopus 로고
    • Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: A possible role for interleukin 6 in cancer cachexia
    • (1992) Cancer Res. , vol.52 , pp. 4113-4116
    • Greenberg, A.S.1
  • 14
    • 0028929156 scopus 로고
    • Interleukin-6 stimulates hepatic triglyceride secretion in rats
    • (1995) Endocrinology , vol.136 , pp. 2143-2149
    • Nonogaki, K.1
  • 17
    • 0343683306 scopus 로고    scopus 로고
    • Body fat distribution, insulin resistance, and metabolic diseases
    • (1997) Nutrition , vol.13 , pp. 795-803
    • Bjorntorp, P.1
  • 19
    • 0032565868 scopus 로고    scopus 로고
    • Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators
    • (1998) Nature , vol.393 , pp. 790-793
    • Staels, B.1
  • 20
    • 0033037150 scopus 로고    scopus 로고
    • Interleukin-6 as a central mediator of cardiovascular risk associated with chronic inflammation, smoking, diabetes, and visceral obesity: Down-regulation with essential fatty acids, ethanol and pentoxifylline
    • (1999) Med. Hypotheses , vol.52 , pp. 465-477
    • McCarty, M.F.1
  • 25
    • 0035836760 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 4652-4657
    • Lambert, P.D.1
  • 28
    • 0029818204 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor is catabolic and shares with IL-6 the capacity to induce an acute phase response
    • (1996) Am. J. Physiol. , vol.271 , pp. R185-R190
    • Espat, N.J.1
  • 29
    • 0033324777 scopus 로고    scopus 로고
    • Activation of SOCS-3 messenger ribonucleic acid in the hypothalamus by ciliary neurotrophic factor
    • (1999) Endocrinology , vol.140 , pp. 2035-2043
    • Bjorbaek, C.1
  • 30
    • 0032518415 scopus 로고    scopus 로고
    • IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses
    • (1998) J. Clin. Invest. , vol.101 , pp. 311-320
    • Xing, Z.1
  • 32
    • 0035408211 scopus 로고    scopus 로고
    • Liver-derived IGF-1 is of importance for normal carbohydrate and lipid metabolism
    • (2001) Diabetes , vol.50 , pp. 1539-1545
    • Sjogren, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.