Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

Nature Medicine

Volumn 15, Issue 8, 2009, Pages 930-939

  Feuerer, Markus ^a,c   Herrero, Laura ^a,c,d   Cipolletta, Daniela ^a,b,c   Naaz, Afia ^a   Wong, Jamie ^a,c,e   Nayer, Ali ^a   Lee, Jongsoon ^a   Goldfine, Allison B ^a   Benoist, Christophe ^a,c   Shoelson, Steven ^a   Mathis, Diane ^a,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b European School of Molecular Medicine   (Italy)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF BARCELONA   (Spain)

^e ALNYLAM PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INTERLEUKIN 10; RANTES; SERUM AMYLOID A; SERUM AMYLOID A 3; STROMELYSIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ABDOMINAL FAT; ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CD25+ T LYMPHOCYTE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL FUNCTION; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE MODEL; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; INSULIN RESISTANCE; INTRAABDOMINAL FAT; LEAN BODY WEIGHT; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; LYMPHOCYTE SUBPOPULATION; MALE; METABOLIC PARAMETERS; MOUSE; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SUBCUTANEOUS FAT;

ADIPOSE TISSUE; ANIMALS; CELL PROLIFERATION; CELL SEPARATION; GENE EXPRESSION PROFILING; LYMPHOCYTE COUNT; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED C57BL; MICE, OBESE; OBESITY; T-LYMPHOCYTES, REGULATORY; THINNESS; UP-REGULATION;

MUS;

EID: 68349148211     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2002     Document Type: Article

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