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Volumn 15, Issue 4, 2012, Pages 518-533

Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; MYELOID DIFFERENTIATION FACTOR 88; PALMITIC ACID; TOLL LIKE RECEPTOR 4;

EID: 84859449180     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2012.01.023     Document Type: Article
Times cited : (442)

References (54)
  • 1
    • 67349205002 scopus 로고    scopus 로고
    • Kupffer cells in non-alcoholic fatty liver disease: The emerging view
    • G. Baffy Kupffer cells in non-alcoholic fatty liver disease: the emerging view J. Hepatol. 51 2009 212 223
    • (2009) J. Hepatol. , vol.51 , pp. 212-223
    • Baffy, G.1
  • 2
    • 0022445268 scopus 로고
    • Cytotoxicity of human pI 7 Interleukin-1 for pancreatic islets of Langerhans
    • K. Bendtzen, T. Mandrup-Poulsen, J. Nerup, J.H. Nielsen, C.A. Dinarello, and M. Svenson Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans Science 232 1986 1545 1547 (Pubitemid 16061563)
    • (1986) Science , vol.232 , Issue.4757 , pp. 1545-1547
    • Bendtzen, K.1    Mandrup-Poulsen, T.2    Nerup, J.3
  • 3
  • 4
    • 67349173942 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale
    • P.C. Calder Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale Biochimie 91 2009 791 795
    • (2009) Biochimie , vol.91 , pp. 791-795
    • Calder, P.C.1
  • 5
    • 0034005968 scopus 로고    scopus 로고
    • Prolonged elevation of plasma free fatty acids impairs pancreatic β- cell function in obese nondiabetic humans but not in individuals with type 2
    • A. Carpentier, S.D. Mittelman, R.N. Bergman, A. Giacca, and G.F. Lewis Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes Diabetes 49 2000 399 408 (Pubitemid 30131785)
    • (2000) Diabetes , vol.49 , Issue.3 , pp. 399-408
    • Carpentier, A.1    Mittelman, S.D.2    Bergman, R.N.3    Giacca, A.4    Lewis, G.F.5
  • 6
    • 0030759095 scopus 로고    scopus 로고
    • The role of non-esterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects: Results of the Paris Prospective study
    • DOI 10.1007/s001250050793
    • M.A. Charles, E. Eschwge, N. Thibult, J.R. Claude, J.M. Warnet, G.E. Rosselin, J. Girard, and B. Balkau The role of non-esterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects: results of the Paris Prospective Study Diabetologia 40 1997 1101 1106 (Pubitemid 27381974)
    • (1997) Diabetologia , vol.40 , Issue.9 , pp. 1101-1106
    • Charles, M.A.1    Eschwege, E.2    Thibult, N.3    Claude, J.-R.4    Warnet, J.-M.5    Rosselin, G.E.6    Girard, J.7    Balkau, B.8
  • 7
    • 45249122276 scopus 로고    scopus 로고
    • Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes
    • DOI 10.1042/BST0360348
    • M. Cnop Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes Biochem. Soc. Trans. 36 2008 348 352 (Pubitemid 351839329)
    • (2008) Biochemical Society Transactions , vol.36 , Issue.3 , pp. 348-352
    • Cnop, M.1
  • 9
    • 79151478555 scopus 로고    scopus 로고
    • Type 2 diabetes as an inflammatory disease
    • M.Y. Donath, and S.E. Shoelson Type 2 diabetes as an inflammatory disease Nat. Rev. Immunol. 11 2011 98 107
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 98-107
    • Donath, M.Y.1    Shoelson, S.E.2
  • 12
    • 73349117487 scopus 로고    scopus 로고
    • Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome
    • M.B. Fessler, L.L. Rudel, and J.M. Brown Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome Curr. Opin. Lipidol. 20 2009 379 385
    • (2009) Curr. Opin. Lipidol. , vol.20 , pp. 379-385
    • Fessler, M.B.1    Rudel, L.L.2    Brown, J.M.3
  • 13
    • 79959897450 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and pancreatic β-cell death
    • S.G. Fonseca, J. Gromada, and F. Urano Endoplasmic reticulum stress and pancreatic β-cell death Trends Endocrinol. Metab. 22 2011 266 274
    • (2011) Trends Endocrinol. Metab. , vol.22 , pp. 266-274
    • Fonseca, S.G.1    Gromada, J.2    Urano, F.3
  • 14
    • 33646692002 scopus 로고    scopus 로고
    • Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent
    • DOI 10.1084/jem.20052205
    • E. Galkina, A. Kadl, J. Sanders, D. Varughese, I.J. Sarembock, and K. Ley Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent J. Exp. Med. 203 2006 1273 1282 (Pubitemid 43736596)
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.5 , pp. 1273-1282
    • Galkina, E.1    Kadl, A.2    Sanders, J.3    Varughese, D.4    Sarembock, I.J.5    Ley, K.6
  • 16
    • 33746834076 scopus 로고    scopus 로고
    • The Effects of Diet on Inflammation. Emphasis on the Metabolic Syndrome
    • DOI 10.1016/j.jacc.2006.03.052, PII S0735109706013350
    • D. Giugliano, A. Ceriello, and K. Esposito The effects of diet on inflammation: emphasis on the metabolic syndrome J. Am. Coll. Cardiol. 48 2006 677 685 (Pubitemid 44175717)
    • (2006) Journal of the American College of Cardiology , vol.48 , Issue.4 , pp. 677-685
    • Giugliano, D.1    Ceriello, A.2    Esposito, K.3
  • 18
    • 80755184725 scopus 로고    scopus 로고
    • Aberrant accumulation of undifferentiated myeloid cells in the adipose tissue of CCR2-deficient mice delays improvements in insulin sensitivity
    • D.A. Gutierrez, A. Kennedy, J.S. Orr, E.K. Anderson, C.D. Webb, W.K. Gerrald, and A.H. Hasty Aberrant accumulation of undifferentiated myeloid cells in the adipose tissue of CCR2-deficient mice delays improvements in insulin sensitivity Diabetes 60 2011 2820 2829
    • (2011) Diabetes , vol.60 , pp. 2820-2829
    • Gutierrez, D.A.1    Kennedy, A.2    Orr, J.S.3    Anderson, E.K.4    Webb, C.D.5    Gerrald, W.K.6    Hasty, A.H.7
  • 19
    • 33845589453 scopus 로고    scopus 로고
    • Understanding and addressing the epidemic of obesity: An energy balance perspective
    • DOI 10.1210/er.2006-0032
    • J.O. Hill Understanding and addressing the epidemic of obesity: an energy balance perspective Endocr. Rev. 27 2006 750 761 (Pubitemid 44936058)
    • (2006) Endocrine Reviews , vol.27 , Issue.7 , pp. 750-761
    • Hill, J.O.1
  • 21
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • DOI 10.1038/nature05485, PII NATURE05485
    • G.S. Hotamisligil Inflammation and metabolic disorders Nature 444 2006 860 867 (Pubitemid 46024993)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 860-867
    • Hotamisligil, G.S.1
  • 22
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • G.S. Hotamisligil Endoplasmic reticulum stress and the inflammatory basis of metabolic disease Cell 140 2010 900 917
    • (2010) Cell , vol.140 , pp. 900-917
    • Hotamisligil, G.S.1
  • 23
    • 0028969155 scopus 로고
    • Turnover of ethyl-linoleate in rat plasma and its distribution in various organs
    • B.L. Hungund, Z. Zheng, and A.I. Barkai Turnover of ethyl-linoleate in rat plasma and its distribution in various organs Alcohol. Clin. Exp. Res. 19 1995 374 377
    • (1995) Alcohol. Clin. Exp. Res. , vol.19 , pp. 374-377
    • Hungund, B.L.1    Zheng, Z.2    Barkai, A.I.3
  • 24
    • 20444482821 scopus 로고    scopus 로고
    • Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: Application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes
    • DOI 10.1074/jbc.M414381200
    • T. Iype, J. Francis, J.C. Garmey, J.C. Schisler, R. Nesher, G.C. Weir, T.C. Becker, C.B. Newgard, S.C. Griffen, and R.G. Mirmira Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes J. Biol. Chem. 280 2005 16798 16807 (Pubitemid 41389138)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.17 , pp. 16798-16807
    • Iype, T.1    Francis, J.2    Garmey, J.C.3    Schisler, J.C.4    Nesher, R.5    Weir, G.C.6    Becker, T.C.7    Newgard, C.B.8    Griffen, S.C.9    Mirmira, R.G.10
  • 25
    • 63649108380 scopus 로고    scopus 로고
    • The roles of TLRs, RLRs and NLRs in pathogen recognition
    • T. Kawai, and S. Akira The roles of TLRs, RLRs and NLRs in pathogen recognition Int. Immunol. 21 2009 317 337
    • (2009) Int. Immunol. , vol.21 , pp. 317-337
    • Kawai, T.1    Akira, S.2
  • 26
    • 33644670203 scopus 로고    scopus 로고
    • Plasma fatty acid composition is associated with the metabolic syndrome and low-grade inflammation in overweight adolescents
    • C. Klein-Platat, J. Drai, M. Oujaa, J.L. Schlienger, and C. Simon Plasma fatty acid composition is associated with the metabolic syndrome and low-grade inflammation in overweight adolescents Am. J. Clin. Nutr. 82 2005 1178 1184 (Pubitemid 43779715)
    • (2005) American Journal of Clinical Nutrition , vol.82 , Issue.6 , pp. 1178-1184
    • Klein-Platat, C.1    Drai, J.2    Oujaa, M.3    Schlienger, J.-L.4    Simon, C.5
  • 28
    • 19944390213 scopus 로고    scopus 로고
    • Pathogenesis of type 2 diabetes mellitus
    • DOI 10.1016/j.arcmed.2005.01.003, PII S0188440905000044, Current Trends in Diabetes
    • J.L. Leahy Pathogenesis of type 2 diabetes mellitus Arch. Med. Res. 36 2005 197 209 (Pubitemid 40755133)
    • (2005) Archives of Medical Research , vol.36 , Issue.3 , pp. 197-209
    • Leahy, J.L.1
  • 29
    • 0035907302 scopus 로고    scopus 로고
    • Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
    • J.Y. Lee, K.H. Sohn, S.H. Rhee, and D. Hwang Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4 J. Biol. Chem. 276 2001 16683 16689
    • (2001) J. Biol. Chem. , vol.276 , pp. 16683-16689
    • Lee, J.Y.1    Sohn, K.H.2    Rhee, S.H.3    Hwang, D.4
  • 30
    • 7444234167 scopus 로고    scopus 로고
    • Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of β-cell function
    • DOI 10.2337/diacare.27.11.2597
    • Y. Li, W. Xu, Z. Liao, B. Yao, X. Chen, Z. Huang, G. Hu, and J. Weng Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of beta-cell function Diabetes Care 27 2004 2597 2602 (Pubitemid 39441457)
    • (2004) Diabetes Care , vol.27 , Issue.11 , pp. 2597-2602
    • Li, Y.1    Xu, W.2    Liao, Z.3    Yao, B.4    Chen, X.5    Huang, Z.6    Hu, G.7    Weng, J.8
  • 32
    • 44849112223 scopus 로고    scopus 로고
    • T cells in the pathogenesis of type 1 diabetes
    • R. Mallone, and P. van Endert T cells in the pathogenesis of type 1 diabetes Curr. Diab. Rep. 8 2008 101 106
    • (2008) Curr. Diab. Rep. , vol.8 , pp. 101-106
    • Mallone, R.1    Van Endert, P.2
  • 33
    • 33748792296 scopus 로고    scopus 로고
    • Acute insulin response (AIR): Review of protocols and clinical interest in islet transplantation
    • DOI 10.1016/S1262-3636(07)70283-5
    • S. Marcelli-Tourvieille, T. Hubert, F. Pattou, and M.C. Vantyghem Acute insulin response (AIR): review of protocols and clinical interest in islet transplantation Diabetes Metab. 32 2006 295 303 (Pubitemid 44410142)
    • (2006) Diabetes and Metabolism , vol.32 , Issue.4 , pp. 295-303
    • Marcelli-Tourvieille, S.1    Hubert, T.2    Pattou, F.3    Vantyghem, M.C.4
  • 34
    • 44649144546 scopus 로고    scopus 로고
    • Relationships between insulin secretion after intravenous and oral glucose administration in subjects with glucose tolerance ranging from normal to overt diabetes
    • DOI 10.1111/j.1464-5491.2008.02441.x
    • A. Mari, A. Tura, G. Pacini, A. Kautzky-Willer, and E. Ferrannini Relationships between insulin secretion after intravenous and oral glucose administration in subjects with glucose tolerance ranging from normal to overt diabetes Diabet. Med. 25 2008 671 677 (Pubitemid 351782827)
    • (2008) Diabetic Medicine , vol.25 , Issue.6 , pp. 671-677
    • Mari, A.1    Tura, A.2    Pacini, G.3    Kautzky-Willer, A.4    Ferrannini, E.5
  • 35
    • 70350188297 scopus 로고    scopus 로고
    • Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome
    • Published online August 12, 2009
    • E. Maury, and S.M. Brichard Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome Mol. Cell. Endocrinol. 314 2010 1 16 Published online August 12, 2009
    • (2010) Mol. Cell. Endocrinol. , vol.314 , pp. 1-16
    • Maury, E.1    Brichard, S.M.2
  • 36
    • 0025281303 scopus 로고
    • Establishment of a pancreatic β cell line that retains glucose-inducible insulin secretion: Special reference to expression of glucose transporter isoforms
    • J. Miyazaki, K. Araki, E. Yamato, H. Ikegami, T. Asano, Y. Shibasaki, Y. Oka, and K. Yamamura Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms Endocrinology 127 1990 126 132 (Pubitemid 20228111)
    • (1990) Endocrinology , vol.127 , Issue.1 , pp. 126-132
    • Miyazaki, J.-I.1    Araki, K.2    Yamato, E.3    Ikegami, H.4    Asano, T.5    Shibasaki, Y.6    Oka, Y.7    Yamamura, K.-I.8
  • 37
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • D.M. Mosser, and J.P. Edwards Exploring the full spectrum of macrophage activation Nat. Rev. Immunol. 8 2008 958 969
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 39
    • 33745863033 scopus 로고    scopus 로고
    • Islet β cell failure in type 2 diabetes
    • DOI 10.1172/JCI29103
    • M. Prentki, and C.J. Nolan Islet beta cell failure in type 2 diabetes J. Clin. Invest. 116 2006 1802 1812 (Pubitemid 44033300)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 42
    • 57649195613 scopus 로고    scopus 로고
    • Dietary fats and prevention of type 2 diabetes
    • U. Risérus, W.C. Willett, and F.B. Hu Dietary fats and prevention of type 2 diabetes Prog. Lipid Res. 48 2009 44 51
    • (2009) Prog. Lipid Res. , vol.48 , pp. 44-51
    • Risérus, U.1    Willett, W.C.2    Hu, F.B.3
  • 43
    • 51349156218 scopus 로고    scopus 로고
    • Insulin sensitivity: Modulation by nutrients and inflammation
    • S. Schenk, M. Saberi, and J.M. Olefsky Insulin sensitivity: modulation by nutrients and inflammation J. Clin. Invest. 118 2008 2992 3002
    • (2008) J. Clin. Invest. , vol.118 , pp. 2992-3002
    • Schenk, S.1    Saberi, M.2    Olefsky, J.M.3
  • 46
    • 20944433543 scopus 로고    scopus 로고
    • The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse
    • DOI 10.1016/j.cmet.2005.03.007, PII S1550413105000860
    • P. Steneberg, N. Rubins, R. Bartoov-Shifman, M.D. Walker, and H. Edlund The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse Cell Metab. 1 2005 245 258 (Pubitemid 43960613)
    • (2005) Cell Metabolism , vol.1 , Issue.4 , pp. 245-258
    • Steneberg, P.1    Rubins, N.2    Bartoov-Shifman, R.3    Walker, M.D.4    Edlund, H.5
  • 47
    • 77954672503 scopus 로고    scopus 로고
    • Adipose tissue macrophages: Their role in adipose tissue remodeling
    • T. Suganami, and Y. Ogawa Adipose tissue macrophages: their role in adipose tissue remodeling J. Leukoc. Biol. 88 2010 33 39
    • (2010) J. Leukoc. Biol. , vol.88 , pp. 33-39
    • Suganami, T.1    Ogawa, Y.2
  • 50
    • 0037343188 scopus 로고    scopus 로고
    • Contribution of fatty acids released from lipolysis of plasma triglycerides to total plasma fatty acid flux and tissue-specific fatty acid uptake
    • DOI 10.2337/diabetes.52.3.614
    • B. Teusink, P.J. Voshol, V.E. Dahlmans, P.C. Rensen, H. Pijl, J.A. Romijn, and L.M. Havekes Contribution of fatty acids released from lipolysis of plasma triglycerides to total plasma fatty acid flux and tissue-specific fatty acid uptake Diabetes 52 2003 614 620 (Pubitemid 36323566)
    • (2003) Diabetes , vol.52 , Issue.3 , pp. 614-620
    • Teusink, B.1    Voshol, P.J.2    Dahlmans, V.E.H.3    Rensen, P.C.N.4    Pijl, H.5    Romijn, J.A.6    Havekes, L.M.7
  • 52
    • 0028111256 scopus 로고
    • Liposome mediated depletion of macrophages: Mechanism of action, preparation of liposomes and applications
    • N. Van Rooijen, and A. Sanders Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications J. Immunol. Methods 174 1994 83 93
    • (1994) J. Immunol. Methods , vol.174 , pp. 83-93
    • Van Rooijen, N.1    Sanders, A.2
  • 53
    • 0043168062 scopus 로고    scopus 로고
    • Evidence of expression of endotoxin receptors CD14, toll-like receptors TLR4 and TLR2 and associated molecule MD-2 and of sensitivity to endotoxin (LPS) in islet beta cells
    • DOI 10.1046/j.1365-2249.2003.02211.x
    • M. Vives-Pi, N. Somoza, J. Fernández-Alvarez, F. Vargas, P. Caro, A. Alba, R. Gomis, M.O. Labeta, and R. Pujol-Borrell Evidence of expression of endotoxin receptors CD14, toll-like receptors TLR4 and TLR2 and associated molecule MD-2 and of sensitivity to endotoxin (LPS) in islet beta cells Clin. Exp. Immunol. 133 2003 208 218 (Pubitemid 36918595)
    • (2003) Clinical and Experimental Immunology , vol.133 , Issue.2 , pp. 208-218
    • Vives-Pi, M.1    Somoza, N.2    Fernandez-Alvarez, J.3    Vargas, F.4    Caro, P.5    Alba, A.6    Gomis, R.7    Labeta, M.O.8    Pujol-Borrell, R.9
  • 54
    • 33750217236 scopus 로고    scopus 로고
    • Lipotoxicity
    • DOI 10.1038/sj.ki.5001834, PII 5001834
    • J.M. Weinberg Lipotoxicity Kidney Int. 70 2006 1560 1566 (Pubitemid 44606990)
    • (2006) Kidney International , vol.70 , Issue.9 , pp. 1560-1566
    • Weinberg, J.M.1


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