Regulation of NT-PGC-1αsubcellular localization and function by protein kinase A-dependent modulation of nuclear export by CRM1

Journal of Biological Chemistry

Volumn 285, Issue 23, 2010, Pages 18039-18050

  Chang, Ji Suk ^a   Huypens, Peter ^a   Zhang, Yubin ^a,c   Black, Chelsea ^a   Kralli, Anastasia ^b   Gettys, Thomas W ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR ENERGY; METABOLIC ADAPTATION; N-TERMINAL TRANSACTIVATION; NUCLEAR EXPORT; NUCLEAR HORMONE RECEPTOR; NUCLEAR PROTEINS; NUCLEAR RECEPTORS; NUTRITIONAL STIMULI; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PROTEASOMES; PROTEIN KINASE A; SITE DIRECTED MUTAGENESIS; SPLICE VARIANTS; SUBCELLULAR LOCALIZATIONS; TRANSCRIPTIONAL ACTIVITY; TRANSCRIPTIONAL CO-ACTIVATORS; UBIQUITIN;

AMINO ACIDS; CYTOLOGY; METABOLISM; ORGANIC ACIDS; PHOSPHORYLATION; TRANSCRIPTION FACTORS;

ENVIRONMENTAL REGULATIONS;

CELL NUCLEUS RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; EXPORTIN 1; HORMONE RECEPTOR; LEUCINE; NUCLEAR PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEASOME; SERINE; THREONINE; TRANSCRIPTION FACTOR; UBIQUITIN;

ANIMAL CELL; ARTICLE; CELL ENERGY; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; ENERGY METABOLISM; FEMALE; GENETIC REGULATION; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN TARGETING; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; SITE DIRECTED MUTAGENESIS; TRANSACTIVATION; TRANSCRIPTION INITIATION;

ANIMALS; BASE SEQUENCE; CELL NUCLEUS; CHO CELLS; CRICETINAE; CRICETULUS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE EXPRESSION REGULATION; KARYOPHERINS; MICE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANS-ACTIVATORS;

EID: 77952931582     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.083121     Document Type: Article

References (55)

1. Finck, B. N., and Kelly, D. P. (2006) J. Clin. Invest. 116, 615-622
2. Handschin, C., and Spiegelman, B. M. (2006) Endocr. Rev. 27, 728-735
3. Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., and Spiegelman, B. M. (1998) Cell 92, 829-839
4. Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B., Scarpulla, R. C., and Spiegelman, B. M. (1999) Cell 98, 115-124
5. Lehman, J. J., Barger, P. M., Kovacs, A., Saffitz, J. E., Medeiros, D. M., and Kelly, D. P. (2000) J. Clin. Invest. 106, 847-856
6. Mootha, V. K., Lindgren, C. M., Eriksson, K. F., Subramanian, A., Sihag, S., Lehar, J., Puigserver, P., Carlsson, E., Ridderstråle, M., Laurila, E., Houstis, N., Daly, M. J., Patterson, N., Mesirov, J. P., Golub, T. R., Tamayo, P., Spiegelman, B., Lander, E. S., Hirschhorn, J. N., Altshuler, D., and Groop, L. C. (2003) Nat. Genet. 34, 267-273
7. Schreiber, S. N., Emter, R., Hock, M. B., Knutti, D., Cardenas, J., Podvinec, M., Oakeley, E. J., and Kralli, A. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 6472-6477
8. Vega, R. B., Huss, J. M., and Kelly, D. P. (2000) Mol. Cell Biol. 20, 1868-1876
9. Wang, Y. X., Lee, C. H., Tiep, S., Yu, R. T., Ham, J., Kang, H., and Evans, R. M. (2003) Cell 113, 159-170
10. Herzig, S., Long, F., Jhala, U. S., Hedrick, S., Quinn, R., Bauer, A., Rudolph, D., Schutz, G., Yoon, C., Puigserver, P., Spiegelman, B., and Montminy, M. (2001) Nature 413, 179-183
11. Yoon, J. C., Puigserver, P., Chen, G., Donovan, J., Wu, Z., Rhee, J., Adelmant, G., Stafford, J., Kahn, C. R., Granner, D. K., Newgard, C. B., and Spiegelman, B. M. (2001) Nature 413, 131-138
12. Kressler, D., Schreiber, S. N., Knutti, D., and Kralli, A. (2002) J. Biol. Chem. 277, 13918-13925
13. Puigserver, P., and Spiegelman, B. M. (2003) Endo. Rev. 24, 78-90
14. Rhee, J., Inoue, Y., Yoon, J. C., Puigserver, P., Fan, M., Gonzalez, F. J., and Spiegelman, B. M. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 4012-4017
15. Lin, J., Wu, H., Tarr, P. T., Zhang, C. Y., Wu, Z., Boss, O., Michael, L. F., Puigserver, P., Isotani, E., Olson, E. N., Lowell, B. B., Bassel-Duby, R., and Spiegelman, B. M. (2002) Nature 418, 797-801
16. St-Pierre, J., Drori, S., Uldry, M., Silvaggi, J. M., Rhee, J., Jäger, S., Handschin, C., Zheng, K., Lin, J., Yang, W., Simon, D. K., Bachoo, R., and Spiegelman, B. M. (2006) Cell 127, 397-408
17. Liu, C., Li, S., Liu, T., Borjigin, J., and Lin, J. D. (2007) Nature 447, 477-481
18. Puigserver, P., Adelmant, C., Wu, Z., Fan, M., Xu, J., O'Malley, B., and Spiegelman, B. M. (1999) Science 286, 1368-1371
19. Delerive, P., Wu, Y., Burris, T. P., Chin, W. W., and Suen, C. S. (2002) J. Biol. Chem. 277, 3913-3917
20. Michael, L. F., Wu, Z., Cheatham, R. B., Puigserver, P., Adelmant, G., Lehman, J. J., Kelly, D. P., and Spiegelman, B. M. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 3820-3825
21. Lin, J., Puigserver, P., Donovan, J., Tarr, P., and Spiegelman, B. M. (2002) J. Biol. Chem. 277, 1645-1648
22. Puigserver, P., Rhee, J., Donovan, J., Walkey, C. J., Yoon, J. C., Oriente, F., Kitamura, Y., Altomonte, J., Dong, H., Accili, D., and Spiegelman, B. M. (2003) Nature 423, 550-555
23. Fan, M., Rhee, J., St-Pierre, J., Handschin, C., Puigserver, P., Lin, J., Jaeger, S., Erdjument-Bromage, H., Tempst, P., and Spiegelman, B. M. (2004) Genes Dev. 18, 278-289
24. Monsalve, M., Wu, Z., Adelmant, G., Puigserver, P., Fan, M., and Spiegelman, B. M. (2000) Mol. Cell 6, 307-316
25. Handschin, C., Rhee, J., Lin, J., Tarr, P. T., and Spiegelman, B. M. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 7111-7116
26. Nisoli, E., Clementi, E., Paolucci, C., Cozzi, V., Tonello, C., Sciorati, C., Bracale, R., Valerio, A., Francolini, M., Moncada, S., and Carruba, M. O. (2003) Science 299, 896-899
27. Cao, W., Daniel, K. W., Robidoux, J., Puigserver, P., Medvedev, A. V., Bai, X., Floering, L. M., Spiegelman, B. M., and Collins, S. (2004) Mol. Cell Biol. 24, 3057-3067
28. Puigserver, P., Rhee, J., Lin, J., Wu, Z., Yoon, J. C., Zhang, C. Y., Krauss, S., Mootha, V. K., Lowell, B. B., and Spiegelman, B. M. (2001) Mol. Cell 8, 971-982
29. Sano, M., Tokudome, S., Shimizu, N., Yoshikawa, N., Ogawa, C., Shirakawa, K., Endo, J., Katayama, T., Yuasa, S., Ieda, M., Makino, S., Hattori, F., Tanaka, H., and Fukuda, K. (2007) J. Biol. Chem. 282, 25970-25980
30. Olson, B. L., Hock, M. B., Ekholm-Reed, S., Wohlschlegel, J. A., Dev, K. K., Kralli, A., and Reed, S. I. (2008) Genes Dev. 22, 252-264
31. Knutti, D., Kressler, D., and Kralli, A. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 9713-9718
32. Jäger, S., Handschin, C., St-Pierre, J., and Spiegelman, B. M. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 12017-12022
33. Li, X., Monks, B., Ge, Q., and Birnbaum, M. J. (2007) Nature 447, 1012-1016
34. Teyssier, C., Ma, H., Emter, R., Kralli, A., and Stallcup, M. R. (2005) Genes Dev. 19, 1466-1473
35. Rodgers, J. T., Lerin, C., Haas, W., Gygi, S. P., Spiegelman, B. M., and Puigserver, P. (2005) Nature 434, 113-118
36. Zhang, Y., Huypens, P., Adamson, A. W., Chang, J. S., Henagan, T. M., Boudreau, A., Lenard, N. R., Burk, D., Klein, J., Perwitz, N., Shin, J., Fasshauer, M., Kralli, A., and Gettys, T. W. (2009) J. Biol. Chem. 284, 32813-32826
37. Biggs, W. H., 3rd, Meisenhelder, J., Hunter, T., Cavenee, W. K., and Arden, K. C. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 7421-7426
38. Brunet, A., Kanai, F., Stehn, J., Xu, J., Sarbassova, D., Frangioni, J. V., Dalal, S. N., DeCaprio, J. A., Greenberg, M. E., and Yaffe, M. B. (2002) J. Cell Biol. 156, 817-828
39. Hayden, M. S., and Ghosh, S. (2004) Genes Dev. 18, 2195-2224
40. Sasaki, T., Kojima, H., Kishimoto, R., Ikeda, A., Kunimoto, H., and Nakajima, K. (2006) Mol. Cell 24, 63-75
41. Roux, P., Blanchard, J. M., Fernandez, A., Lamb, N., Jeanteur, P., and Piechaczyk, M. (1990) Cell 63, 341-351
42. Uldry, M., Yang, W., St-Pierre, J., Lin, J., Seale, P., and Spiegelman, B. M. (2006) Cell Metab. 3, 333-341
43. Béréziat, V., Moritz, S., Klonjkowski, B., Decaudain, A., Auclair, M., Eloit, M., Capeau, J., and Vigouroux, C. (2005) Biochimie 87, 951-958
44. Zhang, Y., and Xiong, Y. (2001) Science 292, 1910-1915
45. Qu, L., Huang, S., Baltzis, D., Rivas-Estilla, A. M., Pluquet, O., Hatzoglou, M., Koumenis, C., Taya, Y., Yoshimura, A., and Koromilas, A. E. (2004) Genes Dev. 18, 261-277
46. Villena, J. A., Hock, M. B., Chang, W. Y., Barcas, J. E., Giguère, V., and Kralli, A. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 1418-1423
47. Panté, N., and Aebi, U. (1996) Crit. Rev. Biochem. Mol. Biol. 31, 153-199
48. Cyert, M. S. (2001) J. Biol. Chem. 276, 20805-20808
49. Kudo, N., Matsumori, N., Taoka, H., Fujiwara, D., Schreiner, E. P., Wolff, B., Yoshida, M., and Horinouchi, S. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 9112-9117
50. Sachdev, S., Bagchi, S., Zhang, D. D., Mings, A. C., and Hannink, M. (2000) Mol. Cell Biol. 20, 1571-1582
51. Stade, K., Ford, C. S., Guthrie, C., and Weis, K. (1997) Cell 90, 1041-1050
52. Hallberg, M., Morganstein, D. L., Kiskinis, E., Shah, K., Kralli, A., Dilworth, S. M., White, R., Parker, M. G., and Christian, M. (2008) Mol. Cell Biol. 28, 6785-6795
53. Sadana, P., and Park, E. A. (2007) Biochem. J. 403, 511-518
54. Yang, J., Bardes, E. S., Moore, J. D., Brennan, J., Powers, M. A., and Kornbluth, S. (1998) Genes Dev. 12, 2131-2143
55. Kilstrup-Nielsen, C., Alessio, M., and Zappavigna, V. (2003) EMBO J. 22, 89-99