-
1
-
-
33846596863
-
Phototransduction, dark adaptation, and rhodopsin regeneration the proctor lecture
-
Lamb TD, Pugh EN, (2006) Phototransduction, dark adaptation, and rhodopsin regeneration the proctor lecture. Invest Ophthalmol Vis Sci 47: 5137-5152.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 5137-5152
-
-
Lamb, T.D.1
Pugh, E.N.2
-
2
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin J, Handschin C, Spiegelman BM, (2005) Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab 1: 361-370.
-
(2005)
Cell Metab
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
3
-
-
33845596500
-
Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
-
Handschin C, Spiegelman BM, (2006) Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. Endocr Rev 27: 728-735.
-
(2006)
Endocr Rev
, vol.27
, pp. 728-735
-
-
Handschin, C.1
Spiegelman, B.M.2
-
4
-
-
33644660537
-
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
-
Finck BN, Kelly DP, (2006) PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J Clin Invest 116: 615-622.
-
(2006)
J Clin Invest
, vol.116
, pp. 615-622
-
-
Finck, B.N.1
Kelly, D.P.2
-
5
-
-
68649109608
-
The biology of PGC-1alpha and its therapeutic potential
-
Handschin C, (2009) The biology of PGC-1alpha and its therapeutic potential. Trends Pharmacol Sci 30: 322-329.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 322-329
-
-
Handschin, C.1
-
6
-
-
0023161084
-
Molecular biology of visual pigments
-
Nathans J, (1987) Molecular biology of visual pigments. Ann Rev Neurosci 10: 2897-2908.
-
(1987)
Ann Rev Neurosci
, vol.10
, pp. 2897-2908
-
-
Nathans, J.1
-
7
-
-
0026574214
-
Energy metabolism of rabbit retina as related to function: high cost of Na+ transport
-
Ames A, Li YY, Heher EC, Kimble CR, (1992) Energy metabolism of rabbit retina as related to function: high cost of Na+ transport. J Neurosci 12: 840-853.
-
(1992)
J Neurosci
, vol.12
, pp. 840-853
-
-
Ames, A.1
Li, Y.Y.2
Heher, E.C.3
Kimble, C.R.4
-
8
-
-
57649201567
-
ATP Consumption by Mammalian Rod Photoreceptors in Darkness and Light
-
Okawa H, Sampath AP, Laughlin SB, Fain GF, (2008) ATP Consumption by Mammalian Rod Photoreceptors in Darkness and Light. Curr Biol 18: 1917-1921.
-
(2008)
Curr Biol
, vol.18
, pp. 1917-1921
-
-
Okawa, H.1
Sampath, A.P.2
Laughlin, S.B.3
Fain, G.F.4
-
9
-
-
82755178018
-
Peroxisome proliferator-activated receptor and age-related macular degeneration
-
Herzlich AA, Ding X, Shen D, Ross RJ, Tuo J, et al. (2009) Peroxisome proliferator-activated receptor and age-related macular degeneration. Open Biol J 2: 141-148.
-
(2009)
Open Biol J
, vol.2
, pp. 141-148
-
-
Herzlich, A.A.1
Ding, X.2
Shen, D.3
Ross, R.J.4
Tuo, J.5
-
10
-
-
77956369911
-
Improvements of retinal vascular injury in diabetic rats by statins is associated with the inhibition of mitochondrial reactive oxygen species pathway mediated by peroxisome-proliferator- activated receptor gamma coactivator 1 alpha
-
Zheng Z, Chen H, Wang H, Ke B, Zheng B, et al. (2010) Improvements of retinal vascular injury in diabetic rats by statins is associated with the inhibition of mitochondrial reactive oxygen species pathway mediated by peroxisome-proliferator- activated receptor gamma coactivator 1 alpha. Diabetes 59: 2315-2325.
-
(2010)
Diabetes
, vol.59
, pp. 2315-2325
-
-
Zheng, Z.1
Chen, H.2
Wang, H.3
Ke, B.4
Zheng, B.5
-
11
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, et al. (2006) Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127: 397-408.
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
-
12
-
-
79551510124
-
The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex
-
Wu J, Ruas JL, Estall JL, Rasbach KA, Choi JH, et al. (2011) The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex. Cell Metab 13: 160-169.
-
(2011)
Cell Metab
, vol.13
, pp. 160-169
-
-
Wu, J.1
Ruas, J.L.2
Estall, J.L.3
Rasbach, K.A.4
Choi, J.H.5
-
13
-
-
35648937073
-
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals
-
Handschin C, Chin S, Li P, Liu F, Maratos-Flier E, et al. (2007) Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals. J Biol Chem 282: 30014-30021.
-
(2007)
J Biol Chem
, vol.282
, pp. 30014-30021
-
-
Handschin, C.1
Chin, S.2
Li, P.3
Liu, F.4
Maratos-Flier, E.5
-
14
-
-
47949104798
-
The role of exercise and PGC-1alpha in inflammation and chronic disease
-
Handschin C, Spiegelman BM, (2008) The role of exercise and PGC-1alpha in inflammation and chronic disease. Nature 454: 463-469.
-
(2008)
Nature
, vol.454
, pp. 463-469
-
-
Handschin, C.1
Spiegelman, B.M.2
-
15
-
-
0034194277
-
Photoreceptor phagocytosis selectively activates PPARgamma expression in retinal pigment epithelial cells
-
Ershov AV, Bazan NG, (2000) Photoreceptor phagocytosis selectively activates PPARgamma expression in retinal pigment epithelial cells. J Neurosci Res 60: 328-337.
-
(2000)
J Neurosci Res
, vol.60
, pp. 328-337
-
-
Ershov, A.V.1
Bazan, N.G.2
-
16
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver P, Wu Z, Park CW, Graves R, Wright M, et al. (1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92: 829-839.
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
-
17
-
-
0035734382
-
Nrl is required for rod photoreceptor development
-
Mears AJ, Kondo M, Swain PK, Takada Y, Bush RA, et al. (2001) Nrl is required for rod photoreceptor development. Nat Genet 29: 447-452.
-
(2001)
Nat Genet
, vol.29
, pp. 447-452
-
-
Mears, A.J.1
Kondo, M.2
Swain, P.K.3
Takada, Y.4
Bush, R.A.5
-
18
-
-
33846126652
-
Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene
-
Chang B, Hawes NL, Pardue MT, German AM, Hurd RE, et al. (2007) Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene. Vision Res 47: 624-633.
-
(2007)
Vision Res
, vol.47
, pp. 624-633
-
-
Chang, B.1
Hawes, N.L.2
Pardue, M.T.3
German, A.M.4
Hurd, R.E.5
-
19
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
-
Lin J, Wu P-H, Tarr PT, Lindenberg KS, St-Pierre J, et al. (2004) Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell 119: 121-135.
-
(2004)
Cell
, vol.119
, pp. 121-135
-
-
Lin, J.1
Wu, P.-H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
-
20
-
-
0034105724
-
Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration
-
Grimm C, Wenzel A, Hafezi F, Yu S, Redmond TM, et al. (2000) Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration. Nat Genet 25: 63-66.
-
(2000)
Nat Genet
, vol.25
, pp. 63-66
-
-
Grimm, C.1
Wenzel, A.2
Hafezi, F.3
Yu, S.4
Redmond, T.M.5
-
21
-
-
11144273817
-
Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration
-
Wenzel A, Grimm C, Samardzija M, Remé CE, (2005) Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration. Prog Retin Eye Res 24: 275-306.
-
(2005)
Prog Retin Eye Res
, vol.24
, pp. 275-306
-
-
Wenzel, A.1
Grimm, C.2
Samardzija, M.3
Remé, C.E.4
-
22
-
-
77249121028
-
Retinal Light Damage: Mechanisms and Protection
-
Organisciak DT, Vaughan DK, (2010) Retinal Light Damage: Mechanisms and Protection. Prog Retin Eye Res 29: 113-134.
-
(2010)
Prog Retin Eye Res
, vol.29
, pp. 113-134
-
-
Organisciak, D.T.1
Vaughan, D.K.2
-
23
-
-
77956372200
-
Retinitis pigmentosa and other dystrophies
-
Sahel J, Bonnel S, Mrejen S, Paques M, (2010) Retinitis pigmentosa and other dystrophies. Dev Ophthalmol 47: 160-167.
-
(2010)
Dev Ophthalmol
, vol.47
, pp. 160-167
-
-
Sahel, J.1
Bonnel, S.2
Mrejen, S.3
Paques, M.4
-
24
-
-
0027251934
-
Simulation of human autosomal dominant retinitis pigmentosa in transgenic mice expressing a mutated murine opsin gene
-
Naash MI, Hollyfield JG, al-Ubaidi MR, Baehr W, (1993) Simulation of human autosomal dominant retinitis pigmentosa in transgenic mice expressing a mutated murine opsin gene. Proc Natl Acad Sci U S A 90: 5499-5503.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 5499-5503
-
-
Naash, M.I.1
Hollyfield, J.G.2
al-Ubaidi, M.R.3
Baehr, W.4
-
25
-
-
15244346017
-
Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse
-
Daniele LL, Lillo C, Lyubarsky AL, Nikonov SS, Philp N, et al. (2005) Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse. Invest Ophthalmol Vis Sci 46: 2156-2167.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 2156-2167
-
-
Daniele, L.L.1
Lillo, C.2
Lyubarsky, A.L.3
Nikonov, S.S.4
Philp, N.5
-
26
-
-
34248200927
-
Caspase-1 ablation protects photoreceptors in a model of autosomal dominant retinitis pigmentosa
-
Samardzija M, Wenzel A, Thiersch M, Frigg R, Remé C, et al. (2006) Caspase-1 ablation protects photoreceptors in a model of autosomal dominant retinitis pigmentosa. Invest Ophthalmol Vis Sci 47: 5181-5190.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 5181-5190
-
-
Samardzija, M.1
Wenzel, A.2
Thiersch, M.3
Frigg, R.4
Remé, C.5
-
27
-
-
58149385608
-
Leukemia inhibitory factor extends the lifespan of injured photoreceptors in vivo
-
Joly S, Lange C, Thiersch M, Samardzija M, Grimm C, (2008) Leukemia inhibitory factor extends the lifespan of injured photoreceptors in vivo. J Neurosci 28: 13765-13774.
-
(2008)
J Neurosci
, vol.28
, pp. 13765-13774
-
-
Joly, S.1
Lange, C.2
Thiersch, M.3
Samardzija, M.4
Grimm, C.5
-
28
-
-
36048931015
-
Abnormal glucose homeostasis in skeletal muscle - specific PGC-1α knockout mice reveals skeletal muscle - pancreatic β cell crosstalk
-
Handschin C, Choi CS, Chin S, Kim S, Kawamori D, et al. (2007) Abnormal glucose homeostasis in skeletal muscle - specific PGC-1α knockout mice reveals skeletal muscle - pancreatic β cell crosstalk. J Clin Invest 117: 3463-3474.
-
(2007)
J Clin Invest
, vol.117
, pp. 3463-3474
-
-
Handschin, C.1
Choi, C.S.2
Chin, S.3
Kim, S.4
Kawamori, D.5
-
29
-
-
23944476164
-
Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha
-
Handschin C, Lin J, Rhee J, Peyer A-K, Chin S, et al. (2005) Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha. Cell 122: 505-515.
-
(2005)
Cell
, vol.122
, pp. 505-515
-
-
Handschin, C.1
Lin, J.2
Rhee, J.3
Peyer, A.-K.4
Chin, S.5
-
30
-
-
21144446106
-
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis
-
Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, et al. (2005) PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol 3: e101.
-
(2005)
PLoS Biol
, vol.3
-
-
Leone, T.C.1
Lehman, J.J.2
Finck, B.N.3
Schaeffer, P.J.4
Wende, A.R.5
-
31
-
-
79961051184
-
DNA damage induces down-regulation of PEPCK and G6P gene expression through degradation of PGC-1a
-
Kim H, Jee HJ, Yun J, (2011) DNA damage induces down-regulation of PEPCK and G6P gene expression through degradation of PGC-1a. Acta Biochim Biophys Sin (Shanghai) 43: 589-594.
-
(2011)
Acta Biochim Biophys Sin (Shanghai)
, vol.43
, pp. 589-594
-
-
Kim, H.1
Jee, H.J.2
Yun, J.3
-
32
-
-
79953734462
-
PGC-1 coactivators and the regulation of skeletal muscle fiber-type determination
-
Handschin C, Spiegelman BM, (2011) PGC-1 coactivators and the regulation of skeletal muscle fiber-type determination. Cell Metab 13: 351.
-
(2011)
Cell Metab
, vol.13
, pp. 351
-
-
Handschin, C.1
Spiegelman, B.M.2
-
33
-
-
22144434964
-
Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle
-
Arany Z, He H, Lin J, Hoyer K, Handschin C, et al. (2005) Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle. Cell Metab 1: 259-271.
-
(2005)
Cell Metab
, vol.1
, pp. 259-271
-
-
Arany, Z.1
He, H.2
Lin, J.3
Hoyer, K.4
Handschin, C.5
-
34
-
-
0037102256
-
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
-
Lin J, Wu H, Tarr P, Zhang C, Wu Z, et al. (2002) Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres. Nature 418: 797-801.
-
(2002)
Nature
, vol.418
, pp. 797-801
-
-
Lin, J.1
Wu, H.2
Tarr, P.3
Zhang, C.4
Wu, Z.5
-
35
-
-
0035855858
-
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
-
Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, et al. (2001) Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413: 131-138.
-
(2001)
Nature
, vol.413
, pp. 131-138
-
-
Yoon, J.C.1
Puigserver, P.2
Chen, G.3
Donovan, J.4
Wu, Z.5
-
36
-
-
77953812778
-
AMP-activated protein kinase mediates activity-dependent regulation of peroxisome proliferator-activated receptor gamma coactivator-1alpha and nuclear respiratory factor 1 expression in rat visual cortical neurons
-
Yu L, Yang SJ, (2010) AMP-activated protein kinase mediates activity-dependent regulation of peroxisome proliferator-activated receptor gamma coactivator-1alpha and nuclear respiratory factor 1 expression in rat visual cortical neurons. Neuroscience 169: 23-38.
-
(2010)
Neuroscience
, vol.169
, pp. 23-38
-
-
Yu, L.1
Yang, S.J.2
-
37
-
-
67650079889
-
The role of PGC-1alpha on mitochondrial function and apoptotic susceptibility in muscle
-
Adhihetty PJ, Uguccioni G, Leick L, Hidalgo J, Pilegaard H, et al. (2009) The role of PGC-1alpha on mitochondrial function and apoptotic susceptibility in muscle. Am J Physiol Cell Physiol 297: C217-C225.
-
(2009)
Am J Physiol Cell Physiol
, vol.297
-
-
Adhihetty, P.J.1
Uguccioni, G.2
Leick, L.3
Hidalgo, J.4
Pilegaard, H.5
-
38
-
-
75149184537
-
Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha overexpression prevents endothelial apoptosis by increasing ATP/ADP translocase activity
-
Won JC, Park J-Y, Kim YM, Koh EH, Seol S, et al. (2010) Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha overexpression prevents endothelial apoptosis by increasing ATP/ADP translocase activity. Arterioscler Thromb Vasc Biol 30: 290-297.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 290-297
-
-
Won, J.C.1
Park, J.-Y.2
Kim, Y.M.3
Koh, E.H.4
Seol, S.5
-
39
-
-
79955634801
-
Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) is a metabolic regulator of intestinal epithelial cell fate
-
D'Errico I, Salvatore L, Murzilli S, Lo Sasso G, Latorre D, et al. (2011) Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) is a metabolic regulator of intestinal epithelial cell fate. Proc Natl Acad Sci U S A 108: 6603-6608.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 6603-6608
-
-
D'Errico, I.1
Salvatore, L.2
Murzilli, S.3
Lo Sasso, G.4
Latorre, D.5
-
40
-
-
63149183620
-
Vision tests in the mouse: Functional phenotyping with electroretinography
-
Tanimoto N, Muehlfriedel R, Fischer M, Fahl E, Humphries P, et al. (2009) Vision tests in the mouse: Functional phenotyping with electroretinography. Front Biosci 14: 2730-2737.
-
(2009)
Front Biosci
, vol.14
, pp. 2730-2737
-
-
Tanimoto, N.1
Muehlfriedel, R.2
Fischer, M.3
Fahl, E.4
Humphries, P.5
-
41
-
-
70449370002
-
Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography
-
Fischer MD, Huber G, Beck SC, Tanimoto N, Muehlfriedel R, et al. (2009) Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography. PloS ONE 4: e7507.
-
(2009)
PloS ONE
, vol.4
-
-
Fischer, M.D.1
Huber, G.2
Beck, S.C.3
Tanimoto, N.4
Muehlfriedel, R.5
|