Ablation of PGC-1β results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance

PLoS Biology

Volumn 4, Issue 11, 2006, Pages 2042-2056

  Lelliott, Christopher J ^a,b   Medina Gomez, Gema ^a   Petrovic, Natasa ^c   Kis, Adrienn ^a   Feldmann, Helena M ^c   Bjursell, Mikael ^b   Parker, Nadeene ^a   Curtis, Keira ^a   Campbell, Mark ^a   Hu, Ping ^d   Zhang, Dongfang ^d   Litwin, Sheldon E ^d   Zaha, Vlad G ^e   Fountain, Kimberly T ^e   Boudina, Sihem ^e   Jimenez Linan, Mercedes ^a   Blount, Margaret ^a   Lopez, Miguel ^a   Meirhaeghe, Aline ^f   Bohlooly Y, Mohammad ^b   Storlien, Leonard ^b   Strömstedt, Maria ^b   Snaith, Michael ^b   Orešič, Matej ^g   Abel, E Dale ^e   Cannon, Barbara ^c   Vidal Puig, Antonio ^a   more..

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ASTRAZENECA R AND D   (Sweden)

^c STOCKHOLM UNIVERSITY   (Sweden)

^d UNIVERSITY OF UTAH   (United States)

^e UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^f INSTITUT PASTEUR DE LILLE   (France)

^g VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

NORADRENALIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ADRENERGIC RECEPTOR STIMULATING AGENT; MULTIENZYME COMPLEX; PPARGC1A PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVITY; CELL FUNCTION; CONTROLLED STUDY; FATTY LIVER; GENE EXPRESSION; GENE IDENTIFICATION; HEART PERFORMANCE; LIPID DIET; LIPID METABOLISM; LIVER FUNCTION; MITOCHONDRION; MOUSE; NONHUMAN; PHENOTYPE; THERMOGENESIS; ANIMAL; ATHEROGENIC DIET; BODY FAT DISTRIBUTION; BODY WEIGHT; BROWN ADIPOSE TISSUE; COLD; CYTOLOGY; DRUG EFFECT; ENERGY METABOLISM; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEART; HEART MITOCHONDRION; HEART RATE; LIVER; MALE; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; SKELETAL MUSCLE; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE, BROWN; ADIPOSE TISSUE, WHITE; ADRENERGIC AGENTS; ANIMALS; BODY FAT DISTRIBUTION; BODY WEIGHT; COLD; DIET, ATHEROGENIC; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; ENERGY METABOLISM; FEMALE; GENE EXPRESSION REGULATION; HEART; HEART RATE; LIVER; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIA, HEART; MUSCLE, SKELETAL; NOREPINEPHRINE; THERMOGENESIS; TRANS-ACTIVATORS;

EID: 33751022208     PISSN: 15457885     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0040369     Document Type: Article

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