PGC-1α deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis

PLoS Biology

Volumn 3, Issue 4, 2005, Pages 0672-0687

  Leone, Teresa C ^a   Lehman, John J ^a   Finck, Brian N ^a   Schaeffer, Paul J ^a   Wende, Adam R ^a   Boudina, Sihem ^b   Courtois, Michael ^a   Wozniak, David F ^a   Sambandam, Nandakumar ^a   Bernal Mizrachi, Carlos ^a   Chen, Zhouji ^a   Holloszy, John O ^a   Medeiros, Denis M ^c   Schmidt, Robert E ^a   Saffitz, Jeffrey E ^a   Abel, E Dale ^b   Semenkovich, Clay F ^a   Kelly, Daniel P ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c KANSAS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; UNCLASSIFIED DRUG; PPARGC1A PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY FAT; BODY TEMPERATURE; BODY WEIGHT DISORDER; CELL COUNT; CELL VACUOLE; CENTRAL NERVOUS SYSTEM; COLD EXPOSURE; CONTROLLED STUDY; DIET; ENERGY EXPENDITURE; ENERGY METABOLISM; EXERCISE; FATTY LIVER; FEMALE; GENE EXPRESSION; HEART DEVELOPMENT; HEART FUNCTION; HEART RATE; INSULIN RESISTANCE; MALE; METABOLIC DISORDER; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; MUSCLE DISEASE; MUSCLE FUNCTION; MUSCLE TWITCH; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PHENOTYPE; PROTEIN DEFICIENCY; SKELETAL MUSCLE; STARVATION; ANIMAL; BODY WEIGHT; CEREBROVASCULAR DISEASE; ENZYMOLOGY; EXON; GENETIC TRANSCRIPTION; GENETICS; MOLECULAR GENETICS; MOUSE MUTANT; OBESITY;

ANIMALS; BODY WEIGHT; CEREBROVASCULAR DISORDERS; EXONS; FATTY LIVER; FEMALE; INSULIN RESISTANCE; MALE; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MUSCULAR DISEASES; OBESITY; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 21144446106     PISSN: 15449173     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pbio.0030101     Document Type: Article

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