PGC-1α integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscle

Journal of Biological Chemistry

Volumn 283, Issue 33, 2008, Pages 22464-22472

  Pagel Langenickel, Ines ^a   Bao, Jianjun ^a   Joseph, Joshua J ^a   Schwartz, Daniel R ^a   Mantell, Benjamin S ^a   Xu, Xiuli ^a   Raghavachari, Nalini ^a   Sack, Michael N ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; FUNCTIONS; GLUCOSE; INSULIN; LAWS AND LEGISLATION; MUSCLE; NUCLEIC ACIDS; PROBABILITY DENSITY FUNCTION; RNA;

DB/DB MOUSE; INSULIN RECEPTORS; KNOCK OUTS; MITOCHONDRIAL BIOENERGETICS; MITOCHONDRIAL BIOGENESISES; MITOCHONDRIAL DYSFUNCTIONS; MYOTUBES; OVEREXPRESSION; PATHO PHYSIOLOGIES; PIOGLITAZONE; RNA KNOCKDOWNS; SKELETAL MUSCLES; SKELETAL MYOBLASTS; THIAZOLIDINEDIONE;

HORMONES;

GLUCOSE; INSULIN; INSULIN RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; 2,4 THIAZOLIDINEDIONE DERIVATIVE; MITOCHONDRIAL DNA; PIOGLITAZONE; PPARGC1A PROTEIN, MOUSE; RNA; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; ENERGY TRANSFER; INSULIN RESISTANCE; MALE; MITOCHONDRION; MOUSE; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL LINE; CYTOLOGY; DRUG EFFECT; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MOUSE STRAIN; MUSCLE CELL; MUSCLE MITOCHONDRION; OXYGEN CONSUMPTION; PHYSIOLOGY;

ANIMALS; CELL LINE; DNA, MITOCHONDRIAL; ENERGY METABOLISM; GENE EXPRESSION REGULATION; INSULIN; MALE; MICE; MICE, INBRED STRAINS; MITOCHONDRIA, MUSCLE; MUSCLE FIBERS; MUSCLE, SKELETAL; OXYGEN CONSUMPTION; RECEPTOR, INSULIN; RNA; SIGNAL TRANSDUCTION; THIAZOLIDINEDIONES; TRANS-ACTIVATORS;

EID: 53049085274     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800842200     Document Type: Article

References (41)

1. Karlsson, H. K., Ahlsen, M., Zierath, J. R., Wallberg-Henriksson, H., and Koistinen, H. A. (2006) Diabetes 55, 1283-1288
2. Storgaard, H., Song, X. M., Jensen, C. B., Madsbad, S., Bjornholm, M., Vaag, A., and Zierath, J. R. (2001) Diabetes 50, 2770-2778
3. Morino, K., Petersen, K. F., Dufour, S., Befroy, D., Frattini, J., Shatzkes, N., Neschen, S., White, M. F., Bilz, S., Sono, S., Pypaert, M., and Shulman, G. I. (2005) J. Clin. Investig. 115, 3587-3593
4. Petersen, K. F., Dufour, S., Savage, D. B., Bilz, S., Solomon, G., Yonemitsu, S., Cline, G. W., Befroy, D., Zemany, L., Kahn, B. B., Papademetris, X., Rothman, D. L., and Shulman, G. I. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 12587-12594
5. Patti, M. E., Butte, A. J., Crunkhorn, S., Cusi, K., Berria, R., Kashyap, S., Miyazaki, Y., Kohane, I., Costello, M., Saccone, R., Landaker, E. J., Goldfine, A. B., Mun, E., DeFronzo, R., Finlayson, J., Kahn, C. R., and Mandarino, L. J. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 8466-8471
6. Petersen, K. F., Dufour, S., Befroy, D., Garcia, R., and Shulman, G. I. (2004) N. Engl. J. Med. 350, 664-671
7. Befroy, D. E., Petersen, K. F., Dufour, S., Mason, G. F., de Graaf, R. A., Rothman, D. L., and Shulman, G. I. (2007) Diabetes 56, 1376-1381
8. Wei, M., Gibbons, L. W., Mitchell, T. L., Kampert, J. B., Lee, C. D., and Blair, S. N. (1999) Ann. Intern. Med. 130, 89-96
9. Choi, C. S., Fillmore, J. J., Kim, J. K., Liu, Z. X., Kim, S., Collier, E. F., Kulkarni, A., Distefano, A., Hwang, Y. J., Kahn, M., Chen, Y., Yu, C., Moore, I. K., Reznick, R. M., Higashimori, T., and Shulman, G. I. (2007) J. Clin. Investig. 117, 1995-2003
10. Gates, A. C., Bernal-Mizrachi, C., Chinault, S. L., Feng, C., Schneider, J. G., Coleman, T., Malone, J. P., Townsend, R. R., Chakravarthy, M. V., and Semenkovich, C. F. (2007) Cell Metab. 6, 497-505
11. Garcia-Martinez, C., Sibille, B., Solanes, G., Darimont, C., Mace, K., Villarroya, F., and Gomez-Foix, A. M. (2001) FASEB J. 15, 2033-2035
12. Wilson-Fritch, L., Nicoloro, S., Chouinard, M., Lazar, M. A., Chui, P. C., Leszyk, J., Straubhaar, J., Czech, M. P., and Corvera, S. (2004) J. Clin. Investig. 114, 1281-1289
13. Boden, G., Homko, C., Mozzoli, M., Showe, L. C., Nichols, C., and Cheung, P. (2005) Diabetes 54, 880-885
14. Pagel-Langenickel, I., Schwartz, D. R., Arena, R. A., Minerbi, D. C., Johnson, D. T., Waclawiw, M. A., Cannon, R. O., III, Balaban, R. S., Tripodi, D. J., and Sack, M. N. (2007) Am. J. Physiol. Heart Circ. Physiol. 293, 2659-2666
15. Mensink, M., Hesselink, M. K., Russell, A. P., Schaart, G., Sels, J. P., and Schrauwen, P. (2007) Int. J. Obes. (Lond) 31, 1302-1310
16. Accili, D., Drago, J., Lee, E. J., Johnson, M. D., Cool, M. H., Salvatore, P., Asico, L. D., Jose, P. A., Taylor, S. I., and Westphal, H. (1996) Nat. Genet. 12, 106-109
17. Rando, T. A., and Blau, H. M. (1994) J. Cell Biol. 125, 1275-1287
18. Gerhart-Hines, Z., Rodgers, J. T., Bare, O., Lerin, C., Kim, S. H., Mostoslavsky, R., Alt, F. W., Wu, Z., and Puigserver, P. (2007) EMBO J. 26, 1913-1923
19. Bogacka, I., Xie, H., Bray, G. A., and Smith, S. R. (2005) Diabetes 54, 1392-1399
20. Hondares, E., Mora, O., Yubero, P., de la Concepcion, M. R., Iglesias, R., Giralt, M., and Villarroya, F. (2006) Endocrinology 147, 2829-2838
21. Yaspelkis, B. B., III, Lessard, S. J., Reeder, D. W., Limon, J. J., Saito, M., Rivas, D. A., Kvasha, I., and Hawley, J. A. (2007) Am. J. Physiol. Endocrinol. Metab. 293, 941-949
22. Schuler, M., Ali, F., Chambon, C., Duteil, D., Bornert, J. M., Tardivel, A., Desvergne, B., Wahli, W., Chambon, P., and Metzger, D. (2006) Cell Metab. 4, 407-414
23. Deeg, M. A., Buse, J. B., Goldberg, R. B., Kendall, D. M., Zagar, A. J., Jacober, S. J., Khan, M. A., Perez, A. T., and Tan, M. H. (2007) Diabetes Care 30, 2458-2464
24. Handschin, C., Chin, S., Li, P., Liu, F., Maratos-Flier, E., Lebrasseur, N. K., Yan, Z., and Spiegelman, B. M. (2007) J. Biol. Chem. 282, 30014-30021
25. Handschin, C., Choi, C. S., Chin, S., Kim, S., Kawamori, D., Kurpad, A. J., Neubauer, N., Hu, J., Mootha, V. K., Kim, Y. B., Kulkarni, R. N., Shulman, G. I., and Spiegelman, B. M. (2007) J. Clin. Investig. 117, 3463-3474
26. Wende, A. R., Schaeffer, P. J., Parker, G. J., Zechner, C., Han, D. H., Chen, M. M., Hancock, C. R., Lehman, J. J., Huss, J. M., McClain, D. A., Holloszy, J. O., and Kelly, D. P. (2007) J. Biol. Chem. 282, 36642-36651
27. Miura, S., Kai, Y., Ono, M., and Ezaki, O. (2003) J. Biol. Chem. 278, 31385-31390
28. Benton, C. R., Nickerson, J. G., Lally, J., Han, X. X., Holloway, G. P., Glatz, J. F., Luiken, J. J., Graham, T. E., Heikkila, J. J., and Bonen, A. (2008) J. Biol. Chem. 283, 4228-4240
29. Martin, B. C., Warram, J. H., Krolewski, A. S., Bergman, R. N., Soeldner, J. S., and Kahn, C. R. (1992) Lancet 340, 925-929
30. Mootha, V. K., Lindgren, C. M., Eriksson, K. F., Subramanian, A., Sihag, S., Lehar, J., Puigserver, P., Carlsson, E., Ridderstrale, M., Laurila, E., Houstis, N., Daly, M. J., Patterson, N., Mesirov, J. P., Golub, T. R., Tamayo, P., Spiegelman, B., Lander, E. S., Hirschhorn, J. N., Altshuler, D., and Groop, L. C. (2003) Nat. Genet. 34, 267-273
31. Skov, V., Glintborg, D., Knudsen, S., Jensen, T., Kruse, T. A., Tan, Q., Brusgaard, K., Beck-Nielsen, H., and Hojlund, K. (2007) Diabetes 56, 2349-2355
32. Nissen, S. E., and Wolski, K. (2007) N. Engl. J. Med. 356, 2457-2471
33. Wan, Y., Chong, L. W., and Evans, R. M. (2007) Nat. Med. 13, 1496-1503
34. Milne, J. C., Lambert, P. D., Schenk, S., Carney, D. P., Smith, J. J., Gagne, D. J., Jin, L., Boss, O., Perni, R. B., Vu, C. B., Bemis, J. E., Xie, R., Disch, J. S., Ng, P. Y., Nunes, J. J., Lynch, A. V., Yang, H., Galonek, H., Israelian, K., Choy, W., Iffland, A., Lavu, S., Medvedik, O., Sinclair, D. A., Olefsky, J. M., Jirousek, M. R., Elliott, P. J., and Westphal, C. H. (2007) Nature 450, 712-716
35. Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., Pistell, P. J., Poosala, S., Becker, K. G., Boss, O., Gwinn, D., Wang, M., Ramaswamy, S., Fishbein, K. W., Spencer, R. G., Lakatta, E. G., Le Couteur, D., Shaw, R. J., Navas, P., Puigserver, P., Ingram, D. K., de Cabo, R., and Sinclair, D. A. (2006) Nature 444, 337-342
36. Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., Geny, B., Laakso, M., Puigserver, P., and Auwerx, J. (2006) Cell 127, 1109-1122
37. Sun, C., Zhang, F., Ge, X., Yan, T., Chen, X., Shi, X., and Zhai, Q. (2007) Cell Metab. 6, 307-319
38. Arany, Z., Wagner, B. K., Ma, Y., Chinsomboon, J., Laznik, D., and Spiegelman, B. M. (2008) Proc. Natl. Acad. Sci. U. S. A. 105, 4721-4726
39. Liu, L., Zhang, Y., Chen, N., Shi, X., Tsang, B., and Yu, Y. H. (2007) J. Clin. Investig. 117, 1679-1689
40. Blendea, M. C., Jacobs, D., Stump, C. S., McFarlane, S. I., Ogrin, C., Bahtyiar, G., Stas, S., Kumar, P., Sha, Q., Ferrario, C. M., and Sowers, J. R. (2005) Am. J. Physiol. Endocrinol. Metab. 288, 353-359
41. St-Pierre, J., Lin, J., Krauss, S., Tarr, P. T., Yang, R., Newgard, C. B., and Spiegelman, B. M. (2003) J. Biol. Chem. 278, 26597-26603