-
1
-
-
0028955276
-
A novel regulatory pathway of brown fat thermogenesis. Retinoic acid is a transcriptional activator of the mitochondrial uncoupling protein gene
-
Alvarez R., de Andres J., Yubero P., Vinas O., Mampel T., Iglesias R., Giralt M., and Villarroya F. A novel regulatory pathway of brown fat thermogenesis. Retinoic acid is a transcriptional activator of the mitochondrial uncoupling protein gene. J. Biol. Chem. 270 (1995) 5666-5673
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5666-5673
-
-
Alvarez, R.1
de Andres, J.2
Yubero, P.3
Vinas, O.4
Mampel, T.5
Iglesias, R.6
Giralt, M.7
Villarroya, F.8
-
2
-
-
0026100209
-
Glucose transporters: structure, function, and regulation
-
Assimacopoulos-Jeannet F., Cusin I., Greco-Perotto R.M., Terrettaz J., Rohner-Jeanrenaud F., Zarjevski N., and Jeanrenaud B. Glucose transporters: structure, function, and regulation. Biochimie 73 (1991) 67-70
-
(1991)
Biochimie
, vol.73
, pp. 67-70
-
-
Assimacopoulos-Jeannet, F.1
Cusin, I.2
Greco-Perotto, R.M.3
Terrettaz, J.4
Rohner-Jeanrenaud, F.5
Zarjevski, N.6
Jeanrenaud, B.7
-
3
-
-
0342334561
-
Molecular approach to thermogenesis in brown adipose tissue: cDNA cloning of the mitochondrial uncoupling protein
-
Bouillaud F., Ricquier D., Thibault J., and Weissenbach J. Molecular approach to thermogenesis in brown adipose tissue: cDNA cloning of the mitochondrial uncoupling protein. Proc. Natl. Acad. Sci. USA 82 (1985) 445-448
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 445-448
-
-
Bouillaud, F.1
Ricquier, D.2
Thibault, J.3
Weissenbach, J.4
-
4
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp T.R., Bernards R., and Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 296 (2002) 550-553
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
5
-
-
0033592536
-
Adaptive thermogenesis: orchestrating mitochondrial biogenesis
-
Butow R.A., and Bahassi E.M. Adaptive thermogenesis: orchestrating mitochondrial biogenesis. Curr. Biol. 9 (1999) R767-R769
-
(1999)
Curr. Biol.
, vol.9
-
-
Butow, R.A.1
Bahassi, E.M.2
-
6
-
-
0347989317
-
Brown adipose tissue: function and physiological significance
-
Cannon B., and Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol. Rev. 84 (2004) 277-359
-
(2004)
Physiol. Rev.
, vol.84
, pp. 277-359
-
-
Cannon, B.1
Nedergaard, J.2
-
7
-
-
0025885770
-
Replication and transcription of vertebrate mitochondrial DNA
-
Clayton D.A. Replication and transcription of vertebrate mitochondrial DNA. Annu. Rev. Cell Biol. 7 (1991) 453-478
-
(1991)
Annu. Rev. Cell Biol.
, vol.7
, pp. 453-478
-
-
Clayton, D.A.1
-
8
-
-
0034749546
-
Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes
-
Fasshauer M., Klein J., Kriauciunas K.M., Ueki K., Benito M., and Kahn C.R. Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes. Mol. Cell. Biol. 21 (2001) 319-329
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 319-329
-
-
Fasshauer, M.1
Klein, J.2
Kriauciunas, K.M.3
Ueki, K.4
Benito, M.5
Kahn, C.R.6
-
9
-
-
0030661665
-
Dominant negative mutants of TRAF3 reveal an important role for the coiled coil domains in cell death signaling by the lymphotoxin-beta receptor
-
Force W.R., Cheung T.C., and Ware C.F. Dominant negative mutants of TRAF3 reveal an important role for the coiled coil domains in cell death signaling by the lymphotoxin-beta receptor. J. Biol. Chem. 272 (1997) 30835-30840
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30835-30840
-
-
Force, W.R.1
Cheung, T.C.2
Ware, C.F.3
-
10
-
-
0025260137
-
Brown adipose tissue thermogenesis: interdisciplinary studies
-
Himms-Hagen J. Brown adipose tissue thermogenesis: interdisciplinary studies. FASEB J. 4 (1990) 2890-2898
-
(1990)
FASEB J.
, vol.4
, pp. 2890-2898
-
-
Himms-Hagen, J.1
-
11
-
-
0037174798
-
Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha
-
Huss J.M., Kopp R.P., and Kelly D.P. Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha. J. Biol. Chem. 277 (2002) 40265-40274
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40265-40274
-
-
Huss, J.M.1
Kopp, R.P.2
Kelly, D.P.3
-
12
-
-
1542373685
-
Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
-
Kelly D.P., and Scarpulla R.C. Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev. 18 (2004) 357-368
-
(2004)
Genes Dev.
, vol.18
, pp. 357-368
-
-
Kelly, D.P.1
Scarpulla, R.C.2
-
13
-
-
0036010603
-
Novel adipocyte lines from brown fat: a model system for the study of differentiation, energy metabolism, and insulin action
-
Klein J., Fasshauer M., Klein H.H., Benito M., and Kahn C.R. Novel adipocyte lines from brown fat: a model system for the study of differentiation, energy metabolism, and insulin action. Bioessays 24 (2002) 382-388
-
(2002)
Bioessays
, vol.24
, pp. 382-388
-
-
Klein, J.1
Fasshauer, M.2
Klein, H.H.3
Benito, M.4
Kahn, C.R.5
-
14
-
-
0032901360
-
Structure and function of the uncoupling protein from brown adipose tissue
-
Klingenberg M., and Huang S.G. Structure and function of the uncoupling protein from brown adipose tissue. Biochim. Biophys. Acta 1415 (1999) 271-296
-
(1999)
Biochim. Biophys. Acta
, vol.1415
, pp. 271-296
-
-
Klingenberg, M.1
Huang, S.G.2
-
15
-
-
0028865142
-
Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity
-
Kopecky J., Clarke G., Enerback S., Spiegelman B., and Kozak L.P. Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity. J. Clin. Invest. 96 (1995) 2914-2923
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 2914-2923
-
-
Kopecky, J.1
Clarke, G.2
Enerback, S.3
Spiegelman, B.4
Kozak, L.P.5
-
16
-
-
21144446106
-
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis
-
10.1371/journal.pbio.0030101
-
Leone T.C., Lehman J.J., Finck B.N., Schaeffer P.J., Wende A.R., Boudina S., Courtois M., Wozniak D.F., Sambandam N., Bernal-Mizrachi C., et al. PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol. 3 (2005) e101 10.1371/journal.pbio.0030101
-
(2005)
PLoS Biol.
, vol.3
-
-
Leone, T.C.1
Lehman, J.J.2
Finck, B.N.3
Schaeffer, P.J.4
Wende, A.R.5
Boudina, S.6
Courtois, M.7
Wozniak, D.F.8
Sambandam, N.9
Bernal-Mizrachi, C.10
-
17
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin J., Handschin C., and Spiegelman B.M. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 1 (2005) 361-370
-
(2005)
Cell Metab.
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
18
-
-
0037127204
-
Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta), a novel PGC-1-related transcription coactivator associated with host cell factor
-
Lin J., Puigserver P., Donovan J., Tarr P., and Spiegelman B.M. Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta), a novel PGC-1-related transcription coactivator associated with host cell factor. J. Biol. Chem. 277 (2002) 1645-1648
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1645-1648
-
-
Lin, J.1
Puigserver, P.2
Donovan, J.3
Tarr, P.4
Spiegelman, B.M.5
-
19
-
-
0042232315
-
PGC-1beta in the regulation of hepatic glucose and energy metabolism
-
Lin J., Tarr P.T., Yang R., Rhee J., Puigserver P., Newgard C.B., and Spiegelman B.M. PGC-1beta in the regulation of hepatic glucose and energy metabolism. J. Biol. Chem. 278 (2003) 30843-30848
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 30843-30848
-
-
Lin, J.1
Tarr, P.T.2
Yang, R.3
Rhee, J.4
Puigserver, P.5
Newgard, C.B.6
Spiegelman, B.M.7
-
20
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
-
Lin J., Wu P.H., Tarr P.T., Lindenberg K.S., St-Pierre J., Zhang C.Y., Mootha V.K., Jager S., Vianna C.R., Reznick R.M., et al. Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell 119 (2004) 121-135
-
(2004)
Cell
, vol.119
, pp. 121-135
-
-
Lin, J.1
Wu, P.H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
Zhang, C.Y.6
Mootha, V.K.7
Jager, S.8
Vianna, C.R.9
Reznick, R.M.10
-
21
-
-
19944430411
-
Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP
-
Lin J., Yang R., Tarr P.T., Wu P.H., Handschin C., Li S., Yang W., Pei L., Uldry M., Tontonoz P., et al. Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP. Cell 120 (2005) 261-273
-
(2005)
Cell
, vol.120
, pp. 261-273
-
-
Lin, J.1
Yang, R.2
Tarr, P.T.3
Wu, P.H.4
Handschin, C.5
Li, S.6
Yang, W.7
Pei, L.8
Uldry, M.9
Tontonoz, P.10
-
22
-
-
0014105013
-
Studies of the mitochondrial energy-transfer system of brown adipose tissue
-
Lindberg O., de Pierre J., Rylander E., and Afzelius B.A. Studies of the mitochondrial energy-transfer system of brown adipose tissue. J. Cell Biol. 34 (1967) 293-310
-
(1967)
J. Cell Biol.
, vol.34
, pp. 293-310
-
-
Lindberg, O.1
de Pierre, J.2
Rylander, E.3
Afzelius, B.A.4
-
23
-
-
0034611678
-
Towards a molecular understanding of adaptive thermogenesis
-
Lowell B.B., and Spiegelman B.M. Towards a molecular understanding of adaptive thermogenesis. Nature 404 (2000) 652-660
-
(2000)
Nature
, vol.404
, pp. 652-660
-
-
Lowell, B.B.1
Spiegelman, B.M.2
-
24
-
-
2342477730
-
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle
-
Mootha V.K., Handschin C., Arlow D., Xie X., St Pierre J., Sihag S., Yang W., Altshuler D., Puigserver P., Patterson N., et al. Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proc. Natl. Acad. Sci. USA 101 (2004) 6570-6575
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6570-6575
-
-
Mootha, V.K.1
Handschin, C.2
Arlow, D.3
Xie, X.4
St Pierre, J.5
Sihag, S.6
Yang, W.7
Altshuler, D.8
Puigserver, P.9
Patterson, N.10
-
25
-
-
0037326196
-
Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator
-
Puigserver P., and Spiegelman B.M. Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr. Rev. 24 (2003) 78-90
-
(2003)
Endocr. Rev.
, vol.24
, pp. 78-90
-
-
Puigserver, P.1
Spiegelman, B.M.2
-
26
-
-
0029793299
-
In vitro and in vivo induction of brown adipocyte uncoupling protein (thermogenin) by retinoic acid
-
Puigserver P., Vazquez F., Bonet M.L., Pico C., and Palou A. In vitro and in vivo induction of brown adipocyte uncoupling protein (thermogenin) by retinoic acid. Biochem. J. 317 (1996) 827-833
-
(1996)
Biochem. J.
, vol.317
, pp. 827-833
-
-
Puigserver, P.1
Vazquez, F.2
Bonet, M.L.3
Pico, C.4
Palou, A.5
-
27
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver P., Wu Z., Park C.W., Graves R., Wright M., and Spiegelman B.M. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92 (1998) 829-839
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
28
-
-
0036007024
-
C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway
-
Rosen E.D., Hsu C.H., Wang X., Sakai S., Freeman M.W., Gonzalez F.J., and Spiegelman B.M. C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway. Genes Dev. 16 (2002) 22-26
-
(2002)
Genes Dev.
, vol.16
, pp. 22-26
-
-
Rosen, E.D.1
Hsu, C.H.2
Wang, X.3
Sakai, S.4
Freeman, M.W.5
Gonzalez, F.J.6
Spiegelman, B.M.7
-
29
-
-
0033213631
-
PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro
-
Rosen E.D., Sarraf P., Troy A.E., Bradwin G., Moore K., Milstone D.S., Spiegelman B.M., and Mortensen R.M. PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro. Mol. Cell 4 (1999) 611-617
-
(1999)
Mol. Cell
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
Sarraf, P.2
Troy, A.E.3
Bradwin, G.4
Moore, K.5
Milstone, D.S.6
Spiegelman, B.M.7
Mortensen, R.M.8
-
31
-
-
0038036024
-
Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells
-
St-Pierre J., Lin J., Krauss S., Tarr P.T., Yang R., Newgard C.B., and Spiegelman B.M. Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. J. Biol. Chem. 278 (2003) 26597-26603
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26597-26603
-
-
St-Pierre, J.1
Lin, J.2
Krauss, S.3
Tarr, P.T.4
Yang, R.5
Newgard, C.B.6
Spiegelman, B.M.7
-
32
-
-
0031836663
-
Inhibition of PI 3-kinase and RAS blocks IGF-I and insulin-induced uncoupling protein 1 gene expression in brown adipocytes
-
Teruel T., Valverde A.M., Navarro P., Benito M., and Lorenzo M. Inhibition of PI 3-kinase and RAS blocks IGF-I and insulin-induced uncoupling protein 1 gene expression in brown adipocytes. J. Cell. Physiol. 176 (1998) 99-109
-
(1998)
J. Cell. Physiol.
, vol.176
, pp. 99-109
-
-
Teruel, T.1
Valverde, A.M.2
Navarro, P.3
Benito, M.4
Lorenzo, M.5
-
33
-
-
1342282912
-
Differential roles of insulin receptor substrates in brown adipocyte differentiation
-
Tseng Y.H., Kriauciunas K.M., Kokkotou E., and Kahn C.R. Differential roles of insulin receptor substrates in brown adipocyte differentiation. Mol. Cell. Biol. 24 (2004) 1918-1929
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 1918-1929
-
-
Tseng, Y.H.1
Kriauciunas, K.M.2
Kokkotou, E.3
Kahn, C.R.4
-
34
-
-
0038532266
-
Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes
-
Valverde A.M., Arribas M., Mur C., Navarro P., Pons S., Cassard-Doulcier A.M., Kahn C.R., and Benito M. Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes. J. Biol. Chem. 278 (2003) 10221-10231
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10221-10231
-
-
Valverde, A.M.1
Arribas, M.2
Mur, C.3
Navarro, P.4
Pons, S.5
Cassard-Doulcier, A.M.6
Kahn, C.R.7
Benito, M.8
-
35
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Wu Z., Puigserver P., Andersson U., Zhang C., Adelmant G., Mootha V., Troy A., Cinti S., Lowell B., Scarpulla R.C., and Spiegelman B.M. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98 (1999) 115-124
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
Mootha, V.6
Troy, A.7
Cinti, S.8
Lowell, B.9
Scarpulla, R.C.10
Spiegelman, B.M.11
-
36
-
-
0033083803
-
Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity
-
Wu Z., Rosen E.D., Brun R., Hauser S., Adelmant G., Troy A.E., McKeon C., Darlington G.J., and Spiegelman B.M. Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol. Cell 3 (1999) 151-158
-
(1999)
Mol. Cell
, vol.3
, pp. 151-158
-
-
Wu, Z.1
Rosen, E.D.2
Brun, R.3
Hauser, S.4
Adelmant, G.5
Troy, A.E.6
McKeon, C.7
Darlington, G.J.8
Spiegelman, B.M.9
-
37
-
-
0041353552
-
Cidea-deficient mice have lean phenotype and are resistant to obesity
-
Zhou Z., Yon Toh S., Chen Z., Guo K., Ng C.P., Ponniah S., Lin S.C., Hong W., and Li P. Cidea-deficient mice have lean phenotype and are resistant to obesity. Nat. Genet. 35 (2003) 49-56
-
(2003)
Nat. Genet.
, vol.35
, pp. 49-56
-
-
Zhou, Z.1
Yon Toh, S.2
Chen, Z.3
Guo, K.4
Ng, C.P.5
Ponniah, S.6
Lin, S.C.7
Hong, W.8
Li, P.9
|