메뉴 건너뛰기




Volumn 15, Issue 3, 2009, Pages 259-266

Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation

Author keywords

[No Author keywords available]

Indexed keywords

CD71 ANTIGEN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ESTROGEN; IRON; IRON REGULATORY FACTOR; OXYGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; PROTEIN; REACTIVE OXYGEN METABOLITE; PPARGC1A PROTEIN, MOUSE; PRIMER DNA; TFRC PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN; TRANSFERRIN RECEPTOR;

EID: 62049085382     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.1910     Document Type: Article
Times cited : (316)

References (39)
  • 1
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • Karsenty, G. & Wagner, E.F. Reaching a genetic and molecular understanding of skeletal development. Dev. Cell 2, 389-406 (2002).
    • (2002) Dev. Cell , vol.2 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 2
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • Teitelbaum, S.L. & Ross, F.P. Genetic regulation of osteoclast development and function. Nat. Rev. Genet. 4, 638-649 (2003).
    • (2003) Nat. Rev. Genet , vol.4 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 3
    • 34447132814 scopus 로고    scopus 로고
    • Skeletal remodeling in health and disease
    • Zaidi, M. Skeletal remodeling in health and disease. Nat. Med. 13, 791-801 (2007).
    • (2007) Nat. Med , vol.13 , pp. 791-801
    • Zaidi, M.1
  • 4
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle, W.J., Simonet, W.S. & Lacey, D.L. Osteoclast differentiation and activation. Nature 423, 337-342 (2003).
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 5
    • 33947583822 scopus 로고    scopus 로고
    • Osteoimmunology: Shared mechanisms and crosstalk between the immune and bone systems
    • Takayanagi, H. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat. Rev. Immunol. 7, 292-304 (2007).
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 292-304
    • Takayanagi, H.1
  • 6
    • 33845539490 scopus 로고    scopus 로고
    • Regulation of osteoclast differentiation and function by the CaMK-CREB pathway
    • Sato, K. et al. Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat. Med. 12, 1410-1416 (2006).
    • (2006) Nat. Med , vol.12 , pp. 1410-1416
    • Sato, K.1
  • 7
    • 0030294128 scopus 로고    scopus 로고
    • Mitochondria-rich, proton-secreting epithelial cells
    • Brown, D. & Breton, S. Mitochondria-rich, proton-secreting epithelial cells. J. Exp. Biol. 199, 2345-2358 (1996).
    • (1996) J. Exp. Biol , vol.199 , pp. 2345-2358
    • Brown, D.1    Breton, S.2
  • 8
    • 0037127204 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β), a novel PGC-1-related transcription coactivator associated with host cell factor
    • Lin, J., Puigserver, P., Donovan, J., Tarr, P. & Spiegelman, B.M. Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β), a novel PGC-1-related transcription coactivator associated with host cell factor. J. Biol. Chem. 277, 1645-1648 (2002).
    • (2002) J. Biol. Chem , vol.277 , pp. 1645-1648
    • Lin, J.1    Puigserver, P.2    Donovan, J.3    Tarr, P.4    Spiegelman, B.M.5
  • 9
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the PGC-1 family of transcription coactivators
    • Lin, J., Handschin, C. & Spiegelman, B.M. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 1, 361-370 (2005).
    • (2005) Cell Metab , vol.1 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 10
    • 33749999530 scopus 로고    scopus 로고
    • Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
    • St-Pierre, J. et al. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127, 397-408 (2006).
    • (2006) Cell , vol.127 , pp. 397-408
    • St-Pierre, J.1
  • 11
    • 0031883280 scopus 로고    scopus 로고
    • A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos
    • Ahn, S. et al. A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos. Mol. Cell. Biol. 18, 967-977 (1998).
    • (1998) Mol. Cell. Biol , vol.18 , pp. 967-977
    • Ahn, S.1
  • 12
    • 33751022208 scopus 로고    scopus 로고
    • Ablation of PGC-1β results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance
    • Lelliott, C.J. et al. Ablation of PGC-1β results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance. PLoS Biol. 4, e369 (2006).
    • (2006) PLoS Biol , vol.4
    • Lelliott, C.J.1
  • 13
  • 14
    • 0034572933 scopus 로고    scopus 로고
    • Iron homeostasis: Insights from genetics and animal models
    • Andrews, N.C. Iron homeostasis: insights from genetics and animal models. Nat. Rev. Genet. 1, 208-217 (2000).
    • (2000) Nat. Rev. Genet , vol.1 , pp. 208-217
    • Andrews, N.C.1
  • 15
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver, P. et al. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92, 829-839 (1998).
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1
  • 16
    • 33751400561 scopus 로고    scopus 로고
    • Hypomorphic mutation of PGC-1β causes mitochondrial dysfunction and liver insulin resistance
    • Vianna, C.R. et al. Hypomorphic mutation of PGC-1β causes mitochondrial dysfunction and liver insulin resistance. Cell Metab. 4, 453-464 (2006).
    • (2006) Cell Metab , vol.4 , pp. 453-464
    • Vianna, C.R.1
  • 17
    • 34247590356 scopus 로고    scopus 로고
    • PGC-1β controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis
    • Sonoda, J., Mehl, I.R., Chong, L.W., Nofsinger, R.R. & Evans, R.M. PGC-1β controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis. Proc. Natl. Acad. Sci. USA 104, 5223-5228 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 5223-5228
    • Sonoda, J.1    Mehl, I.R.2    Chong, L.W.3    Nofsinger, R.R.4    Evans, R.M.5
  • 18
    • 33845674997 scopus 로고    scopus 로고
    • The transcriptional coactivator PGC-1β drives the formation of oxidative type IIX fibers in skeletal muscle
    • Arany, Z. et al. The transcriptional coactivator PGC-1β drives the formation of oxidative type IIX fibers in skeletal muscle. Cell Metab. 5, 35-46 (2007).
    • (2007) Cell Metab , vol.5 , pp. 35-46
    • Arany, Z.1
  • 19
    • 22144457305 scopus 로고    scopus 로고
    • A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation
    • Lee, N.K. et al. A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation. Blood 106, 852-859 (2005).
    • (2005) Blood , vol.106 , pp. 852-859
    • Lee, N.K.1
  • 20
    • 0025236484 scopus 로고
    • Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo
    • Garrett, I.R. et al. Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. J. Clin. Invest. 85, 632-639 (1990).
    • (1990) J. Clin. Invest , vol.85 , pp. 632-639
    • Garrett, I.R.1
  • 21
    • 0026637817 scopus 로고
    • Stimulation of osteoclastic bone resorption by hydrogen peroxide
    • Bax, B.E. et al. Stimulation of osteoclastic bone resorption by hydrogen peroxide. Biochem. Biophys. Res. Commun. 183, 1153-1158 (1992).
    • (1992) Biochem. Biophys. Res. Commun , vol.183 , pp. 1153-1158
    • Bax, B.E.1
  • 22
    • 85177147087 scopus 로고    scopus 로고
    • Steinbeck, M.J., Appel, W.H. Jr., Verhoeven, A.J. & , Karnovsky M.J. NADPH-oxidase expression and in situ production of superoxide by osteoclasts actively resorbing bone. J. Cell Biol. 126, 765-772 (1994).
    • Steinbeck, M.J., Appel, W.H. Jr., Verhoeven, A.J. & , Karnovsky M.J. NADPH-oxidase expression and in situ production of superoxide by osteoclasts actively resorbing bone. J. Cell Biol. 126, 765-772 (1994).
  • 23
    • 0142186681 scopus 로고    scopus 로고
    • A crucial role for thiol antioxidants in estrogen-deficiency bone loss
    • Lean, J.M. et al. A crucial role for thiol antioxidants in estrogen-deficiency bone loss. J. Clin. Invest. 112, 915-923 (2003).
    • (2003) J. Clin. Invest , vol.112 , pp. 915-923
    • Lean, J.M.1
  • 24
    • 36849034568 scopus 로고    scopus 로고
    • PPAR-γ regulates osteoclastogenesis in mice
    • Wan, Y., Chong, L.W. & Evans, R.M. PPAR-γ regulates osteoclastogenesis in mice. Nat. Med. 13, 1496-1503 (2007).
    • (2007) Nat. Med , vol.13 , pp. 1496-1503
    • Wan, Y.1    Chong, L.W.2    Evans, R.M.3
  • 25
    • 11144354330 scopus 로고    scopus 로고
    • Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis
    • Koga, T. et al. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature 428, 758-763 (2004).
    • (2004) Nature , vol.428 , pp. 758-763
    • Koga, T.1
  • 26
    • 0042386014 scopus 로고    scopus 로고
    • The IkB function of NF-κB2 p100 controls stimulated osteoclastogenesis
    • Novack, D.V. et al. The IkB function of NF-κB2 p100 controls stimulated osteoclastogenesis. J. Exp. Med. 198, 771-781 (2003).
    • (2003) J. Exp. Med , vol.198 , pp. 771-781
    • Novack, D.V.1
  • 27
    • 33748786241 scopus 로고    scopus 로고
    • Borgna-Pignatti, C. Thalassemia. A few new tiles in a large mosaic. Haematologica 91, 1159-1161 (2006).
    • Borgna-Pignatti, C. Thalassemia. A few new tiles in a large mosaic. Haematologica 91, 1159-1161 (2006).
  • 28
    • 5644257032 scopus 로고    scopus 로고
    • New insights into the pathophysiology and management of osteoporosis in patients with beta thalassaemia
    • Voskaridou, E. & Terpos, E. New insights into the pathophysiology and management of osteoporosis in patients with beta thalassaemia. Br. J. Haematol. 127, 127-139 (2004).
    • (2004) Br. J. Haematol , vol.127 , pp. 127-139
    • Voskaridou, E.1    Terpos, E.2
  • 29
    • 3242795997 scopus 로고    scopus 로고
    • Osteoprotegerin and RANKL in the pathogenesis of thalassemia-induced osteoporosis: New pieces of the puzzle
    • Morabito, N. et al. Osteoprotegerin and RANKL in the pathogenesis of thalassemia-induced osteoporosis: new pieces of the puzzle. J. Bone Miner. Res. 19, 722-727 (2004).
    • (2004) J. Bone Miner. Res , vol.19 , pp. 722-727
    • Morabito, N.1
  • 30
    • 0028925088 scopus 로고
    • Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis
    • Manolagas, S.C. & Jilka, R.L. Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis. N. Engl. J. Med. 332, 305-311 (1995).
    • (1995) N. Engl. J. Med , vol.332 , pp. 305-311
    • Manolagas, S.C.1    Jilka, R.L.2
  • 31
    • 0036732410 scopus 로고    scopus 로고
    • SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts
    • Takeshita, S. et al. SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts. Nat. Med. 8, 943-949 (2002).
    • (2002) Nat. Med , vol.8 , pp. 943-949
    • Takeshita, S.1
  • 32
    • 0036723649 scopus 로고    scopus 로고
    • Novel translational control through an iron-responsive element by interaction of multifunctional protein YB-1 and IRP2
    • Ashizuka, M. et al. Novel translational control through an iron-responsive element by interaction of multifunctional protein YB-1 and IRP2. Mol. Cell. Biol. 22, 6375-6383 (2002).
    • (2002) Mol. Cell. Biol , vol.22 , pp. 6375-6383
    • Ashizuka, M.1
  • 33
    • 4644340208 scopus 로고    scopus 로고
    • Mechanism of the generation of autonomous activity of Ca2+/ calmodulin-dependent protein kinase IV
    • Tokumitsu, H. et al. Mechanism of the generation of autonomous activity of Ca2+/ calmodulin-dependent protein kinase IV. J. Biol. Chem. 279, 40296-40302 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 40296-40302
    • Tokumitsu, H.1
  • 34
    • 0023790708 scopus 로고
    • Osteoblastic cells are involved in osteoclast formation
    • Takahashi, N. et al. Osteoblastic cells are involved in osteoclast formation. Endocrinology 123, 2600-2602 (1988).
    • (1988) Endocrinology , vol.123 , pp. 2600-2602
    • Takahashi, N.1
  • 35
    • 34547103543 scopus 로고    scopus 로고
    • c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages
    • Takeshita, S. et al. c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages. J. Biol. Chem. 282, 18980-18990 (2007).
    • (2007) J. Biol. Chem , vol.282 , pp. 18980-18990
    • Takeshita, S.1
  • 36
    • 0033543569 scopus 로고    scopus 로고
    • Clinical severity and thermodynamic effects of iron-responsive element mutations in hereditary hyperferritinemia-cataract syndrome
    • Allerson, C.R., Cazzola, M. & Rouault, T.A. Clinical severity and thermodynamic effects of iron-responsive element mutations in hereditary hyperferritinemia-cataract syndrome. J. Biol. Chem. 274, 26439-26447 (1999).
    • (1999) J. Biol. Chem , vol.274 , pp. 26439-26447
    • Allerson, C.R.1    Cazzola, M.2    Rouault, T.A.3
  • 37
    • 0017367091 scopus 로고
    • Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process
    • Sassa, S. & Kappas, A. Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process. J. Biol. Chem. 252, 2428-2436 (1977).
    • (1977) J. Biol. Chem , vol.252 , pp. 2428-2436
    • Sassa, S.1    Kappas, A.2
  • 38
    • 25444529444 scopus 로고    scopus 로고
    • Multi-detector row CT imaging of vertebral microstructure for evaluation of fracture risk
    • Ito, M. et al. Multi-detector row CT imaging of vertebral microstructure for evaluation of fracture risk. J. Bone Miner. Res. 20, 1828-1836 (2005).
    • (2005) J. Bone Miner. Res , vol.20 , pp. 1828-1836
    • Ito, M.1
  • 39
    • 34249657953 scopus 로고    scopus 로고
    • Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction
    • Tatsumi, S. et al. Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction. Cell Metab. 5, 464-475 (2007).
    • (2007) Cell Metab , vol.5 , pp. 464-475
    • Tatsumi, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.