Whole body overexpression of PGC-1α has opposite effects on hepatic and muscle insulin sensitivity

American Journal of Physiology - Endocrinology and Metabolism

Volumn 296, Issue 4, 2009, Pages

  Liang, Huiyun ^a   Balas, Bogdan ^a   Tantiwong, Puntip ^a,b   Dube, John ^c   Goodpaster, Bret H ^c   O'Doherty, Robert M ^c   DeFronzo, Ralph A ^a,b   Richardson, Arlan ^a   Musi, Nicolas ^a,b   Ward, Walter F ^a,d  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Texas Diabetes Institute   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d Barshop Institute for Longevity and Aging Studies ^*  (United States)

Author keywords

Diabetes; Gluconeogenesis; Glucose 6 phosphatase; Phosphoenolpyruvate carboxykinase

Indexed keywords

GLUCOSE 6 PHOSPHATASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROTEIN KINASE B; HEAT SHOCK PROTEIN; PPARGC1A PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; GLUCOSE HOMEOSTASIS; HYPERINSULINEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; C57BL MOUSE; DBA MOUSE; FEEDING BEHAVIOR; FEMALE; GENETICS; GLUCONEOGENESIS; HUMAN; LIPID METABOLISM; LIVER; MALE; METABOLISM; MITOCHONDRIAL GENE; PHYSIOLOGY; SKELETAL MUSCLE; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; FEEDING BEHAVIOR; FEMALE; GENES, MITOCHONDRIAL; GLUCONEOGENESIS; HEAT-SHOCK PROTEINS; HUMANS; INSULIN RESISTANCE; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; MUSCLE, SKELETAL; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 65649148341     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.90292.2008     Document Type: Article

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