Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Cell

Volumn 127, Issue 6, 2006, Pages 1109-1122

  Lagouge, Marie ^a   Argmann, Carmen ^a   Gerhart Hines, Zachary ^b   Meziane, Hamid ^c   Lerin, Carles ^b   Daussin, Frederic ^d   Messadeq, Nadia ^c   Milne, Jill ^e   Lambert, Philip ^e   Elliott, Peter ^e   Geny, Bernard ^d   Laakso, Markku ^f   Puigserver, Pere ^b   Auwerx, Johan ^a,c,g  

^a INSERM   (France)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUT CLINIQUE DE LA SOURIS   (France)

^d UNIVERSITY HOSPITAL OF STRASBOURG   (France)

^e GLAXOSMITHKLINE   (United States)

^f UNIVERSITY OF EASTERN FINLAND   (Finland)

^g INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE; OXYGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN SIRT1; RESVERATROL;

ADULT; AEROBIC CAPACITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CONTROLLED STUDY; DISEASE MODEL; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; FINLAND; GENE; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; LIFESPAN; LONGEVITY; MAJOR CLINICAL STUDY; MALE; METABOLIC DISORDER; MITOCHONDRION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTECTION; SINGLE NUCLEOTIDE POLYMORPHISM; SIRT1 GENE;

ACETYLATION; ADULT; ANIMALS; DIETARY FATS; ENERGY METABOLISM; GENE EXPRESSION REGULATION; HUMANS; INSULIN RESISTANCE; MALE; METABOLIC DISEASES; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MITOCHONDRIA, MUSCLE; MOTOR ACTIVITY; MUSCLE FIBERS; OBESITY; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SIRTUINS; SPECIFIC PATHOGEN-FREE ORGANISMS; STILBENES; TRANS-ACTIVATORS;

RICE STRIPE VIRUS;

EID: 33845399894     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2006.11.013     Document Type: Article

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