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Volumn 391, Issue 6662, 1998, Pages 79-82

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY DELTA 12,14 PROSTAGLANDIN J 2; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN J2; SCAVENGER RECEPTOR; STAT1 PROTEIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

EID: 0031886864     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/34178     Document Type: Article
Times cited : (3339)

References (27)
  • 1
    • 0028321529 scopus 로고
    • Differential expression and activation of a family of murine peroxisome proliferator-activated receptors
    • Kliewer, S. A. et al. Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc. Natl Acad. Sci. USA 91, 7355-7359 (1994).
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 7355-7359
    • Kliewer, S.A.1
  • 2
    • 0029731662 scopus 로고    scopus 로고
    • PPARs: A nuclear receptor signaling pathway in lipid metabolism
    • Lemberger, T., Desvergne, B. & Wahli, W. PPARs: a nuclear receptor signaling pathway in lipid metabolism. Annu. Rev. Cell Dev. Biol. 12, 335-363 (1996).
    • (1996) Annu. Rev. Cell Dev. Biol. , vol.12 , pp. 335-363
    • Lemberger, T.1    Desvergne, B.2    Wahli, W.3
  • 3
    • 0028180070 scopus 로고
    • mPPAR gamma 2: Tissue-specific regulator of an adipocyte enhancer
    • Tontonoz, P., Hu, E., Graves, R. A., Budavari, A. I. & Spiegelman, B. M. mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev. 8, 1224-1234 (1994).
    • (1994) Genes Dev. , vol.8 , pp. 1224-1234
    • Tontonoz, P.1    Hu, E.2    Graves, R.A.3    Budavari, A.I.4    Spiegelman, B.M.5
  • 4
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
    • Tontonoz, P., Hu, E. & Spiegelman, B. M. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 79, 1147-1156 (1994).
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 5
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome prolifereator-activated receptor gamma (PPARgamma)
    • Lehmann, J. M. et al. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome prolifereator-activated receptor gamma (PPARgamma). J. Biol. Chem. 270, 12953-12956 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1
  • 6
    • 0030062325 scopus 로고    scopus 로고
    • The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones
    • Willson, T. M. et al. The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J. Med. Chem. 39, 665-668 (1996).
    • (1996) J. Med. Chem. , vol.39 , pp. 665-668
    • Willson, T.M.1
  • 7
    • 0028972026 scopus 로고
    • 2 metabolite binds peroxisome proliferator-activated receptorγ and promotes adipocyte differentiation
    • 2 metabolite binds peroxisome proliferator-activated receptorγ and promotes adipocyte differentiation. Cell 83, 813-819 (1995).
    • (1995) Cell , vol.83 , pp. 813-819
    • Kliewer, S.A.1
  • 8
    • 0028972025 scopus 로고
    • 2 is a ligand for the adipocyte determination factor PPARγ
    • 2 is a ligand for the adipocyte determination factor PPARγ. Cell 83, 803-812 (1995).
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1
  • 9
    • 0006132932 scopus 로고    scopus 로고
    • Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ
    • Kliewer, S. A. et al. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ. Proc. Natl Acad. Sci. USA 94, 4318-4323 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 4318-4323
    • Kliewer, S.A.1
  • 10
    • 0030985318 scopus 로고    scopus 로고
    • Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
    • Krey, G. et al. Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol. Endocrinol. 11, 779-791 (1997).
    • (1997) Mol. Endocrinol. , vol.11 , pp. 779-791
    • Krey, G.1
  • 12
    • 0027368278 scopus 로고
    • Macrophage nitric oxide synthase gene: Two upstream regions mediate induction by interferon gamma and lipopolysaccharide
    • Lowenstein, C. J. et al. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide. Proc. Natl Acad. Sci. USA 90, 8730-9734 (1993).
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 8730-9734
    • Lowenstein, C.J.1
  • 13
    • 0030917135 scopus 로고    scopus 로고
    • Potent hypocholesterolemic activity of novel ureido phenoxyisobutyrates correlates with their intrinsic fibrate potency and not with their ACAT inhibitory activity
    • Hawke, R. L. et al. Potent hypocholesterolemic activity of novel ureido phenoxyisobutyrates correlates with their intrinsic fibrate potency and not with their ACAT inhibitory activity. J. Lipid Res. 38, 1189-1203 (1997).
    • (1997) J. Lipid Res. , vol.38 , pp. 1189-1203
    • Hawke, R.L.1
  • 14
    • 0026896029 scopus 로고
    • The matrix degrading metalloproteinases
    • Matrisian, L. M. The matrix degrading metalloproteinases. BioEssays 14, 455-463 (1992).
    • (1992) BioEssays , vol.14 , pp. 455-463
    • Matrisian, L.M.1
  • 15
    • 0025059594 scopus 로고
    • Neutral metalloproteinases produced by human mononuclear phagocytes
    • Welgus, H. G., Campbell, E. .J. & Cury, J. D. Neutral metalloproteinases produced by human mononuclear phagocytes. J. Clin. Invest. 86, 1496-1502 (1990).
    • (1990) J. Clin. Invest. , vol.86 , pp. 1496-1502
    • Welgus, H.G.1    Campbell, E.J.2    Cury, J.D.3
  • 16
    • 0029152375 scopus 로고
    • Isolation of the human peroxisome proliferator activated receptor gamma cDNA: Expression in hematopoietic cells and chromosomal mapping
    • Greene, M. E. et al. Isolation of the human peroxisome proliferator activated receptor gamma cDNA: expression in hematopoietic cells and chromosomal mapping. Gene Express. 4, 281-299 (1995).
    • (1995) Gene Express. , vol.4 , pp. 281-299
    • Greene, M.E.1
  • 17
    • 0027219989 scopus 로고
    • Distinct mechanisms regulate interstitial collagenase and 92-kDa gelatinase expression in human monocytic-like cells exposed to bacterial endotoxin
    • Saarialho-Kere, U. K., Welgus, H. G. & Parks, W. C. Distinct mechanisms regulate interstitial collagenase and 92-kDa gelatinase expression in human monocytic-like cells exposed to bacterial endotoxin. J. Biol. Chem. 268, 17354-17361 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 17354-17361
    • Saarialho-Kere, U.K.1    Welgus, H.G.2    Parks, W.C.3
  • 18
    • 0027439698 scopus 로고
    • Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells
    • Sato, H. & Seiki, M. Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene 8, 395-405 (1993).
    • (1993) Oncogene , vol.8 , pp. 395-405
    • Sato, H.1    Seiki, M.2
  • 19
    • 0028173897 scopus 로고
    • Structures and functions of multiligand lipoprotein receptors: Macrophage scavenger receptors and LDL receptor-related protein (LRP)
    • Krieger, M. & Herz, J. Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP). Annu. Rev. Biochem. 63, 601-637 (1994).
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 601-637
    • Krieger, M.1    Herz, J.2
  • 20
    • 0028258246 scopus 로고
    • Combinatorial interactions between AP-1 and ets-domain proteins contribute to the developmental regulation of the macrophage scavenger gene
    • Wu, H., Moulton, K., Horvai, A., Parik, S. & Glass, C. K. Combinatorial interactions between AP-1 and ets-domain proteins contribute to the developmental regulation of the macrophage scavenger gene. Mol. Cell. Biol. 14, 2129-2139 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2129-2139
    • Wu, H.1    Moulton, K.2    Horvai, A.3    Parik, S.4    Glass, C.K.5
  • 21
    • 0027255749 scopus 로고
    • Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide
    • Xie, Q. W., Whisnant, R. & Nathan, C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide. J. Exp. Med. 177, 1779-1784 (1993).
    • (1993) J. Exp. Med. , vol.177 , pp. 1779-1784
    • Xie, Q.W.1    Whisnant, R.2    Nathan, C.3
  • 22
    • 0027459588 scopus 로고
    • Expression ofthe nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide
    • Lorsbach, R. B., Murphy, W. J., Lowenstein, C. J., Snyder, S. H. & Russell, S. W. Expression ofthe nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide. J. Biol. Chem. 268, 1908-1913 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 1908-1913
    • Lorsbach, R.B.1    Murphy, W.J.2    Lowenstein, C.J.3    Snyder, S.H.4    Russell, S.W.5
  • 23
    • 0028173207 scopus 로고
    • A new class of retinoids with selective inhibition of AP-1 inhibits proliferation
    • Fanjul, A. et al. A new class of retinoids with selective inhibition of AP-1 inhibits proliferation. Nature 372, 107-111 (1994).
    • (1994) Nature , vol.372 , pp. 107-111
    • Fanjul, A.1
  • 24
    • 0031037363 scopus 로고    scopus 로고
    • Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300
    • Horvai, A. E. et al. Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc. Natl Acad. Sci. USA 94, 1074-1079 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 1074-1079
    • Horvai, A.E.1
  • 26
    • 0020448709 scopus 로고
    • 15N]nitrate in biological fluids
    • 15N]nitrate in biological fluids. Biochemistry 126, 131-138 (1982).
    • (1982) Biochemistry , vol.126 , pp. 131-138
    • Green, L.C.1
  • 27
    • 0029783927 scopus 로고    scopus 로고
    • The murine DUB-1 gene is specifically induced by the βc subunit ofthe interleukin-3 receptor
    • Zhu, Y., Pless, M., Inhorn, R., Mathey-Prevot, B. & D'Andrea, A. D. The murine DUB-1 gene is specifically induced by the βc subunit ofthe interleukin-3 receptor. Mol. Cell. Biol. 16, 4808-4817 (1996).
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4808-4817
    • Zhu, Y.1    Pless, M.2    Inhorn, R.3    Mathey-Prevot, B.4    D'Andrea, A.D.5


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