TNF-α reduces PGC-1α expression through NF-κB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model

Cardiovascular Research

Volumn 81, Issue 4, 2009, Pages 703-712

  Palomer, Xavier ^a   Álvarez Guardia, David ^a   Rodríguez Calvo, Ricardo ^a   Coll, Teresa ^a   Laguna, Juan C ^a   Davidson, Mercy M ^b   Chan, Tung O ^c   Feldman, Arthur M ^c   Vázquez Carrera, Manuel ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

NF B; Peroxisome proliferator activated receptor coactivator 1 ; TNF

Indexed keywords

ESTROGEN RELATED RECEPTOR ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOTRANSFERASE; PYRUVATE DEHYDROGENASE KINASE 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; GLUCOSE OXIDATION; HEART MUSCLE CELL; HEART MUSCLE METABOLISM; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CELL LINE; DOWN-REGULATION; ESTROGEN RECEPTOR ALPHA; GLUCOSE; HEAT-SHOCK PROTEINS; HUMANS; MALE; MICE; MICE, TRANSGENIC; MYOCYTES, CARDIAC; NF-KAPPA B; OXIDATION-REDUCTION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PPAR DELTA; PPAR-BETA; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 60149110303     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvn327     Document Type: Article

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