A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ

Nature

Volumn 437, Issue 7059, 2005, Pages 759-763

  Pascual, Gabriel ^a,b   Fong, Amy L ^a,b   Ogawa, Sumito ^a   Gamliel, Amir ^b   Li, Andrew C ^a   Perissi, Valentina ^b   Rose, David W ^c   Willson, Timothy M ^d   Rosenfeld, Michael G ^b,c   Glass, Christopher K ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; ENZYMES; GENES; MOLECULAR STRUCTURE;

COREPRESSOR COMPLEXES; GENE ACTIVATION; GENE PROMOTERS; LIGANDS;

GENETIC ENGINEERING;

HISTONE DEACETYLASE; NUCLEAR RECEPTOR COREPRESSOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; HDAC3 PROTEIN, MOUSE; HISTONE DEACETYLASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIGAND; LIPOPOLYSACCHARIDE; MULTIPROTEIN COMPLEX; NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, MOUSE; NUCLEAR PROTEIN; NUCLEAR RECEPTOR CO REPRESSOR 1; NUCLEAR RECEPTOR CO-REPRESSOR 1; PIAS1 PROTEIN, MOUSE; PROTEIN; PROTEIN INHIBITOR OF ACTIVATED STAT; REPRESSOR PROTEIN; SUMO 1 PROTEIN;

MEDICINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE CONTROL; GENE IDENTIFICATION; GENE REPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HOMEOSTASIS; IMMUNITY; INFLAMMATION; LIGAND BINDING; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION INITIATION; UBIQUITINATION; ANIMAL; CELL CULTURE; DOWN REGULATION; DRUG EFFECT; GENETICS; METABOLISM; PROTEIN BINDING;

ANIMALIA;

ANIMALS; CELLS, CULTURED; DOWN-REGULATION; HISTONE DEACETYLASES; INFLAMMATION; LIGANDS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MULTIPROTEIN COMPLEXES; NF-KAPPA B; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NUCLEAR PROTEINS; PPAR GAMMA; PROTEIN BINDING; PROTEIN INHIBITORS OF ACTIVATED STAT; PROTEINS; REPRESSOR PROTEINS; SUMO-1 PROTEIN;

EID: 26444471700     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature03988     Document Type: Article

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