-
1
-
-
4043154377
-
Cancer cachexia is regulated by selective targeting of skeletal muscle gene products
-
Acharyya, S., K.J. Ladner, L.L. Nelsen, J. Damrauer, P.J. Reiser, S. Swoap, and D.C. Guttridge. 2004. Cancer cachexia is regulated by selective targeting of skeletal muscle gene products. J. Clin. Invest. 114:370-378.
-
(2004)
J. Clin. Invest
, vol.114
, pp. 370-378
-
-
Acharyya, S.1
Ladner, K.J.2
Nelsen, L.L.3
Damrauer, J.4
Reiser, P.J.5
Swoap, S.6
Guttridge, D.C.7
-
2
-
-
27644471080
-
Dystrophin glycoprotein complex dysfunction: A regulatory link between muscular dystrophy and cancer cachexia
-
Acharyya, S., M.E. Butchbach, Z. Sahenk, H. Wang, M. Saji, M. Carathers, M.D. Ringel, R.J. Skipworth, K.C. Fearon, M.A. Hollingsworth, et al. 2005. Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia. Cancer Cell. 8:421-432.
-
(2005)
Cancer Cell
, vol.8
, pp. 421-432
-
-
Acharyya, S.1
Butchbach, M.E.2
Sahenk, Z.3
Wang, H.4
Saji, M.5
Carathers, M.6
Ringel, M.D.7
Skipworth, R.J.8
Fearon, K.C.9
Hollingsworth, M.A.10
-
3
-
-
34147122660
-
Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy
-
Acharyya, S., S.A. Villalta, N. Bakkar, T. Bupha-Intr, P.M. Janssen, M. Carathers, Z.W. Li, A.A. Beg, S. Ghosh, Z. Sahenk, et al. 2007. Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. J. Clin. Invest. 117:889-901.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 889-901
-
-
Acharyya, S.1
Villalta, S.A.2
Bakkar, N.3
Bupha-Intr, T.4
Janssen, P.M.5
Carathers, M.6
Li, Z.W.7
Beg, A.A.8
Ghosh, S.9
Sahenk, Z.10
-
4
-
-
0037497184
-
A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression
-
Anest, V., J.L. Hanson, P.C. Cogswell, K.A. Steinbrecher, B.D. Strahl, and A.S. Baldwin. 2003. A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression. Nature. 423:659-663.
-
(2003)
Nature
, vol.423
, pp. 659-663
-
-
Anest, V.1
Hanson, J.L.2
Cogswell, P.C.3
Steinbrecher, K.A.4
Strahl, B.D.5
Baldwin, A.S.6
-
5
-
-
1642423481
-
p38 MAPK-induced nuclear factor-kappaB activity is required for skeletal muscle differentiation: Role of interleukin-6
-
Baeza-Raja, B., and P. Munoz-Canoves. 2004. p38 MAPK-induced nuclear factor-kappaB activity is required for skeletal muscle differentiation: role of interleukin-6. Mol. Biol. Cell. 15:2013-2026.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 2013-2026
-
-
Baeza-Raja, B.1
Munoz-Canoves, P.2
-
6
-
-
0032941594
-
Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IkappaB alpha/NF-kappaB pathway in limb-girdle muscular dystrophy type 2A
-
Baghdiguian, S., M. Martin, I. Richard, F. Pons, C. Astier, N. Bourg, R.T. Hay, R. Chemaly, G. Halaby, J. Loiselet, et al. 1999. Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IkappaB alpha/NF-kappaB pathway in limb-girdle muscular dystrophy type 2A. Nat. Med. 5:503-511.
-
(1999)
Nat. Med
, vol.5
, pp. 503-511
-
-
Baghdiguian, S.1
Martin, M.2
Richard, I.3
Pons, F.4
Astier, C.5
Bourg, N.6
Hay, R.T.7
Chemaly, R.8
Halaby, G.9
Loiselet, J.10
-
7
-
-
0028971291
-
Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice
-
Beg, A.A., W.C. Sha, R.T. Bronson, and D. Baltimore. 1995a. Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice. Genes Dev. 9:2736-2746.
-
(1995)
Genes Dev
, vol.9
, pp. 2736-2746
-
-
Beg, A.A.1
Sha, W.C.2
Bronson, R.T.3
Baltimore, D.4
-
8
-
-
0029059060
-
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
-
Beg, A.A., W.C. Sha, R.T. Bronson, S. Ghosh, and D. Baltimore. 1995b. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature. 376:167-170.
-
(1995)
Nature
, vol.376
, pp. 167-170
-
-
Beg, A.A.1
Sha, W.C.2
Bronson, R.T.3
Ghosh, S.4
Baltimore, D.5
-
9
-
-
9144275033
-
Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers
-
Bonizzi, G., M. Bebien, D.C. Otero, K.E. Johnson-Vroom, Y. Cao, D. Vu, A.G. Jegga, B.J. Aronow, G. Ghosh, R.C. Rickert, and M. Karin. 2004. Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. EMBO J. 23:4202-4210.
-
(2004)
EMBO J
, vol.23
, pp. 4202-4210
-
-
Bonizzi, G.1
Bebien, M.2
Otero, D.C.3
Johnson-Vroom, K.E.4
Cao, Y.5
Vu, D.6
Jegga, A.G.7
Aronow, B.J.8
Ghosh, G.9
Rickert, R.C.10
Karin, M.11
-
10
-
-
5444262078
-
IKKbeta/NF-kB activation causes severe muscle wasting in mice
-
Cai, D., J.D. Frantz, N.E. Tawa Jr., P.A. Melendez, B.-C. Oh, W.R. Lidov, P.O. Hasselgren, W.R. Frontera, J. Lee, D.J. Glass, and S.E. Shoelson. 2004. IKKbeta/NF-kB activation causes severe muscle wasting in mice. Cell. 119:285-298.
-
(2004)
Cell
, vol.119
, pp. 285-298
-
-
Cai, D.1
Frantz, J.D.2
Tawa Jr., N.E.3
Melendez, P.A.4
Oh, B.-C.5
Lidov, W.R.6
Hasselgren, P.O.7
Frontera, W.R.8
Lee, J.9
Glass, D.J.10
Shoelson, S.E.11
-
11
-
-
0035827711
-
Nuclear factor kappa B-inducing kinase and Ikappa B kinase-alpha signal skeletal muscle cell differentiation
-
Canicio, J., P. Ruiz-Lozano, M. Carrasco, M. Palacin, K. Chien, A. Zorzano, and P. Kaliman. 2001. Nuclear factor kappa B-inducing kinase and Ikappa B kinase-alpha signal skeletal muscle cell differentiation. J. Biol. Chem. 276:20228-20233.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 20228-20233
-
-
Canicio, J.1
Ruiz-Lozano, P.2
Carrasco, M.3
Palacin, M.4
Chien, K.5
Zorzano, A.6
Kaliman, P.7
-
12
-
-
34250669605
-
TNF-alpha regulates myogenesis and muscle regeneration by activating p38 MAPK
-
Chen, S.E., B. Jin, and Y.P. Li. 2007. TNF-alpha regulates myogenesis and muscle regeneration by activating p38 MAPK. Am. J. Physiol. Cell Physiol. 292:C1660-C1671.
-
(2007)
Am. J. Physiol. Cell Physiol
, vol.292
-
-
Chen, S.E.1
Jin, B.2
Li, Y.P.3
-
13
-
-
0037161993
-
Insulin restores differentiation of Ras-transformed C2C12 myoblasts by inducing NF-kappaB through an AKT/P70S6K/p38-MAPK pathway
-
Conejo, R., C. de Alvaro, M. Benito, A. Cuadrado, and M. Lorenzo. 2002. Insulin restores differentiation of Ras-transformed C2C12 myoblasts by inducing NF-kappaB through an AKT/P70S6K/p38-MAPK pathway. Oncogene. 21:3739-3753.
-
(2002)
Oncogene
, vol.21
, pp. 3739-3753
-
-
Conejo, R.1
de Alvaro, C.2
Benito, M.3
Cuadrado, A.4
Lorenzo, M.5
-
14
-
-
0023663888
-
Expression of a single transfected cDNA converts fibroblasts to myoblasts
-
Davis, R.L., H. Weintraub, and A.B. Lassar. 1987. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell. 51:987-1000.
-
(1987)
Cell
, vol.51
, pp. 987-1000
-
-
Davis, R.L.1
Weintraub, H.2
Lassar, A.B.3
-
15
-
-
18644380147
-
The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways
-
Dejardin, E., N.M. Droin, M. Delhase, E. Haas, Y. Cao, C. Makris, Z.W. Li, M. Karin, C.F. Ware, and D.R. Green. 2002. The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity. 17:525-535.
-
(2002)
Immunity
, vol.17
, pp. 525-535
-
-
Dejardin, E.1
Droin, N.M.2
Delhase, M.3
Haas, E.4
Cao, Y.5
Makris, C.6
Li, Z.W.7
Karin, M.8
Ware, C.F.9
Green, D.R.10
-
16
-
-
27644494143
-
RelB/p52 NF-kappaB complexes rescue an early delay in mammary gland development in transgenic mice with targeted superrepressor IkappaB-alpha expression and promote carcinogenesis of the mammary gland
-
Demicco, E.G., K.T. Kavanagh, R. Romieu-Mourez, X. Wang, S.R. Shin, E. Landesman-Bollag, D.C. Seldin, and G.E. Sonenshein. 2005. RelB/p52 NF-kappaB complexes rescue an early delay in mammary gland development in transgenic mice with targeted superrepressor IkappaB-alpha expression and promote carcinogenesis of the mammary gland. Mol. Cell. Biol. 25:10136-10147.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 10136-10147
-
-
Demicco, E.G.1
Kavanagh, K.T.2
Romieu-Mourez, R.3
Wang, X.4
Shin, S.R.5
Landesman-Bollag, E.6
Seldin, D.C.7
Sonenshein, G.E.8
-
17
-
-
0032980504
-
Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality
-
Doi, T.S., M.W. Marino, T. Takahashi, T. Yoshida, T. Sakakura, L.J. Old, and Y. Obata. 1999. Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality. Proc. Natl. Acad. Sci. USA. 96:2994-2999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2994-2999
-
-
Doi, T.S.1
Marino, M.W.2
Takahashi, T.3
Yoshida, T.4
Sakakura, T.5
Old, L.J.6
Obata, Y.7
-
18
-
-
0031034468
-
Two domains of MyoD mediate transcriptional activation of genes in repressive chromatin: A mechanism for lineage determination in myogenesis
-
Gerber, A.N., T.R. Klesert, D.A. Bergstrom, and S.J. Tapscott. 1997. Two domains of MyoD mediate transcriptional activation of genes in repressive chromatin: a mechanism for lineage determination in myogenesis. Genes Dev. 11:436-450.
-
(1997)
Genes Dev
, vol.11
, pp. 436-450
-
-
Gerber, A.N.1
Klesert, T.R.2
Bergstrom, D.A.3
Tapscott, S.J.4
-
19
-
-
0033596123
-
Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: Transgenics and knockouts
-
Gerondakis, S., M. Grossmann, Y. Nakamura, T. Pohl, and R. Grumont. 1999. Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts. Oncogene. 18:6888-6895.
-
(1999)
Oncogene
, vol.18
, pp. 6888-6895
-
-
Gerondakis, S.1
Grossmann, M.2
Nakamura, Y.3
Pohl, T.4
Grumont, R.5
-
20
-
-
0036234459
-
Missing pieces in the NF-kappaB puzzle
-
Ghosh, S., and M. Karin. 2002. Missing pieces in the NF-kappaB puzzle. Cell. 109:S81-S96.
-
(2002)
Cell
, vol.109
-
-
Ghosh, S.1
Karin, M.2
-
21
-
-
0032588186
-
NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1
-
Guttridge, D.C., C. Albanese, J.Y. Reuther, R.G. Pestell, and A.S. Baldwin Jr. 1999. NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol. Cell. Biol. 19:5785-5799.
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 5785-5799
-
-
Guttridge, D.C.1
Albanese, C.2
Reuther, J.Y.3
Pestell, R.G.4
Baldwin Jr., A.S.5
-
22
-
-
0034730251
-
NF-kB-induced loss of MyoD messenger RNA: Possible role in muscle decay and cachexia
-
Guttridge, D.C., M.W. Mayo, L.V. Madrid, C.-Y. Wang, and A.S. Baldwin Jr. 2000. NF-kB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia. Science. 289:2363-2366.
-
(2000)
Science
, vol.289
, pp. 2363-2366
-
-
Guttridge, D.C.1
Mayo, M.W.2
Madrid, L.V.3
Wang, C.-Y.4
Baldwin Jr., A.S.5
-
23
-
-
4444376712
-
Signaling to NF-kB
-
Hayden, M.S., and S. Ghosh. 2004. Signaling to NF-kB. Genes Dev. 18:2195-2224.
-
(2004)
Genes Dev
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
24
-
-
20344383738
-
RelA/p65 regulation of IkappaBbeta
-
Hertlein, E., J. Wang, K.J. Ladner, N. Bakkar, and D.C. Guttridge. 2005. RelA/p65 regulation of IkappaBbeta. Mol. Cell. Biol. 25:4956-4968.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 4956-4968
-
-
Hertlein, E.1
Wang, J.2
Ladner, K.J.3
Bakkar, N.4
Guttridge, D.C.5
-
25
-
-
6344241039
-
SMRT derepression by the IkappaB kinase alpha: A prerequisite to NF-kappaB transcription and survival
-
Hoberg, J.E., F. Yeung, and M.W. Mayo. 2004. SMRT derepression by the IkappaB kinase alpha: a prerequisite to NF-kappaB transcription and survival. Mol. Cell. 16:245-255.
-
(2004)
Mol. Cell
, vol.16
, pp. 245-255
-
-
Hoberg, J.E.1
Yeung, F.2
Mayo, M.W.3
-
26
-
-
0035809983
-
IKKalpha controls formation of the epidermis independently of NF-kappaB
-
Hu, Y., V. Baud, T. Oga, K.I. Kim, K. Yoshida, and M. Karin. 2001. IKKalpha controls formation of the epidermis independently of NF-kappaB. Nature. 410:710-714.
-
(2001)
Nature
, vol.410
, pp. 710-714
-
-
Hu, Y.1
Baud, V.2
Oga, T.3
Kim, K.I.4
Yoshida, K.5
Karin, M.6
-
27
-
-
11144317940
-
Disruption of either the Nfkb1 or the Bcl3 gene inhibits skeletal muscle atrophy
-
Hunter, R.B., and S.C. Kandarian. 2004. Disruption of either the Nfkb1 or the Bcl3 gene inhibits skeletal muscle atrophy. J. Clin. Invest. 114:1504-1511.
-
(2004)
J. Clin. Invest
, vol.114
, pp. 1504-1511
-
-
Hunter, R.B.1
Kandarian, S.C.2
-
28
-
-
0035169827
-
Mitochondrial DNA instability and peri-implantation lethality associated with targeted disruption of nuclear respiratory factor 1 in mice
-
Huo, L., and R.C. Scarpulla. 2001. Mitochondrial DNA instability and peri-implantation lethality associated with targeted disruption of nuclear respiratory factor 1 in mice. Mol. Cell. Biol. 21:644-654.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 644-654
-
-
Huo, L.1
Scarpulla, R.C.2
-
29
-
-
0032217268
-
The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NFkappaB inactivation
-
Huxford, T., D.B. Huang, S. Malek, and G. Ghosh. 1998. The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NFkappaB inactivation. Cell. 95:759-770.
-
(1998)
Cell
, vol.95
, pp. 759-770
-
-
Huxford, T.1
Huang, D.B.2
Malek, S.3
Ghosh, G.4
-
30
-
-
0030715563
-
Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2
-
Iotsova, V., J. Caamano, J. Loy, Y. Yang, A. Lewin, and R. Bravo. 1997. Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2. Nat. Med. 3:1285-1289.
-
(1997)
Nat. Med
, vol.3
, pp. 1285-1289
-
-
Iotsova, V.1
Caamano, J.2
Loy, J.3
Yang, Y.4
Lewin, A.5
Bravo, R.6
-
31
-
-
0033580826
-
Insulin-like growth factor-II, phosphatidylinositol 3-kinase, nuclear factor-kappaB and inducible nitric-oxide synthase define a common myogenic signaling pathway
-
Kaliman, P., J. Canicio, X. Testar, M. Palacin, and A. Zorzano. 1999. Insulin-like growth factor-II, phosphatidylinositol 3-kinase, nuclear factor-kappaB and inducible nitric-oxide synthase define a common myogenic signaling pathway. J. Biol. Chem. 274:17437-17444.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 17437-17444
-
-
Kaliman, P.1
Canicio, J.2
Testar, X.3
Palacin, M.4
Zorzano, A.5
-
32
-
-
0033595893
-
How NF-kappaB is activated: The role of the IkappaB kinase (IKK) complex
-
Karin, M. 1999. How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex. Oncogene. 18:6867-6874.
-
(1999)
Oncogene
, vol.18
, pp. 6867-6874
-
-
Karin, M.1
-
33
-
-
0037336186
-
Mechanical stress activates the nuclear factor-kappaB pathway in skeletal muscle fibers: A possible role in Duchenne muscular dystrophy
-
Kumar, A., and A.M. Boriek. 2003. Mechanical stress activates the nuclear factor-kappaB pathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy. FASEB J. 17:386-396.
-
(2003)
FASEB J
, vol.17
, pp. 386-396
-
-
Kumar, A.1
Boriek, A.M.2
-
34
-
-
0035020963
-
Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB
-
Langen, R.C., A.M. Schols, M.C. Kelders, E.F. Wouters, and Y.M. Janssen-Heininger. 2001. Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB. FASEB J. 15:1169-1180.
-
(2001)
FASEB J
, vol.15
, pp. 1169-1180
-
-
Langen, R.C.1
Schols, A.M.2
Kelders, M.C.3
Wouters, E.F.4
Janssen-Heininger, Y.M.5
-
35
-
-
0034999617
-
Effect of acute exercise on citrate synthase activity in untrained and trained human skeletal muscle
-
Leek, B.T., S.R. Mudaliar, R. Henry, O. Mathieu-Costello, and R.S. Richardson. 2001. Effect of acute exercise on citrate synthase activity in untrained and trained human skeletal muscle. Am. J. Physiol. Regul. Integr. Comp. Physiol. 280:R441-R447.
-
(2001)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.280
-
-
Leek, B.T.1
Mudaliar, S.R.2
Henry, R.3
Mathieu-Costello, O.4
Richardson, R.S.5
-
36
-
-
18344415234
-
Down-regulation of transcription factors AP-1, Sp-1, and NF-kappa B precedes myocyte differentiation
-
Lehtinen, S.K., P. Rahkila, M. Helenius, P. Korhonen, and A. Salminen. 1996. Down-regulation of transcription factors AP-1, Sp-1, and NF-kappa B precedes myocyte differentiation. Biochem. Biophys. Res. Commun. 229:36-43.
-
(1996)
Biochem. Biophys. Res. Commun
, vol.229
, pp. 36-43
-
-
Lehtinen, S.K.1
Rahkila, P.2
Helenius, M.3
Korhonen, P.4
Salminen, A.5
-
37
-
-
0242416989
-
IKK beta is required for peripheral B cell survival and proliferation
-
Li, Z.W., S.A. Omori, T. Labuda, M. Karin, and R.C. Rickert. 2003. IKK beta is required for peripheral B cell survival and proliferation. J. Immunol. 170:4630-4637.
-
(2003)
J. Immunol
, vol.170
, pp. 4630-4637
-
-
Li, Z.W.1
Omori, S.A.2
Labuda, T.3
Karin, M.4
Rickert, R.C.5
-
38
-
-
0942290423
-
Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells
-
Liu, T., B. Brouha, and D. Grossman. 2004. Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells. Oncogene. 23:39-48.
-
(2004)
Oncogene
, vol.23
, pp. 39-48
-
-
Liu, T.1
Brouha, B.2
Grossman, D.3
-
39
-
-
3843123246
-
Bioenergetic remodeling during cellular differentiation: Changes in cytochrome c oxidase regulation do not affect the metabolic phenotype
-
Lyons, C.N., S.C. Leary, and C.D. Moyes. 2004. Bioenergetic remodeling during cellular differentiation: changes in cytochrome c oxidase regulation do not affect the metabolic phenotype. Biochem. Cell Biol. 82:391-399.
-
(2004)
Biochem. Cell Biol
, vol.82
, pp. 391-399
-
-
Lyons, C.N.1
Leary, S.C.2
Moyes, C.D.3
-
40
-
-
0037465720
-
Activation of nuclear factor-kappaB in inflammatory myopathies and Duchenne muscular dystrophy
-
Monici, M.C., M. Aguennouz, A. Mazzeo, C. Messina, and G. Vita. 2003. Activation of nuclear factor-kappaB in inflammatory myopathies and Duchenne muscular dystrophy. Neurology. 60:993-997.
-
(2003)
Neurology
, vol.60
, pp. 993-997
-
-
Monici, M.C.1
Aguennouz, M.2
Mazzeo, A.3
Messina, C.4
Vita, G.5
-
41
-
-
33750595325
-
Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration
-
Mourkioti, F., P. Kratsios, T. Luedde, Y.H. Song, P. Delafontaine, R. Adami, V. Parente, R. Bottinelli, M. Pasparakis, and N. Rosenthal. 2006. Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration. J. Clin. Invest. 116:2945-2954.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 2945-2954
-
-
Mourkioti, F.1
Kratsios, P.2
Luedde, T.3
Song, Y.H.4
Delafontaine, P.5
Adami, R.6
Parente, V.7
Bottinelli, R.8
Pasparakis, M.9
Rosenthal, N.10
-
42
-
-
0030903943
-
Mitochondrial biogenesis during cellular differentiation
-
Moyes, C.D., O.A. Mathieu-Costello, N. Tsuchiya, C. Filburn, and R.G. Hansford. 1997. Mitochondrial biogenesis during cellular differentiation. Am. J. Physiol. 272:C1345-C1351.
-
(1997)
Am. J. Physiol
, vol.272
-
-
Moyes, C.D.1
Mathieu-Costello, O.A.2
Tsuchiya, N.3
Filburn, C.4
Hansford, R.G.5
-
43
-
-
0036311526
-
RIP2, a checkpoint in myogenic differentiation
-
Munz, B., E. Hildt, M.L. Springer, and H.M. Blau. 2002. RIP2, a checkpoint in myogenic differentiation. Mol. Cell. Biol. 22:5879-5886.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 5879-5886
-
-
Munz, B.1
Hildt, E.2
Springer, M.L.3
Blau, H.M.4
-
44
-
-
0032705145
-
MEF2: A transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation
-
Naya, F.J., and E. Olson. 1999. MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation. Curr. Opin. Cell Biol. 11:683-688.
-
(1999)
Curr. Opin. Cell Biol
, vol.11
, pp. 683-688
-
-
Naya, F.J.1
Olson, E.2
-
45
-
-
33744975264
-
L2L: A simple tool for discovering the hidden significance in microarray expression data
-
Newman, J.C., and A.M. Weiner. 2005. L2L: a simple tool for discovering the hidden significance in microarray expression data. Genome Biol. 6:R81.
-
(2005)
Genome Biol
, vol.6
-
-
Newman, J.C.1
Weiner, A.M.2
-
46
-
-
0033529030
-
pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation
-
Novitch, B.G., D.B. Spicer, P.S. Kim, W.L. Cheung, and A.B. Lassar. 1999. pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation. Curr. Biol. 9:449-459.
-
(1999)
Curr. Biol
, vol.9
, pp. 449-459
-
-
Novitch, B.G.1
Spicer, D.B.2
Kim, P.S.3
Cheung, W.L.4
Lassar, A.B.5
-
47
-
-
0036771765
-
Two pathways to NF-kappaB
-
Pomerantz, J.L., and D. Baltimore. 2002. Two pathways to NF-kappaB. Mol. Cell. 10:693-695.
-
(2002)
Mol. Cell
, vol.10
, pp. 693-695
-
-
Pomerantz, J.L.1
Baltimore, D.2
-
48
-
-
0036437330
-
Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos
-
Pownall, M.E., M.K. Gustafsson, and C.P. Emerson Jr. 2002. Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos. Annu. Rev. Cell Dev. Biol. 18:747-783.
-
(2002)
Annu. Rev. Cell Dev. Biol
, vol.18
, pp. 747-783
-
-
Pownall, M.E.1
Gustafsson, M.K.2
Emerson Jr., C.P.3
-
49
-
-
0028264320
-
Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy
-
Rando, T.A., and H.M. Blau. 1994. Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy. J. Cell Biol. 125:1275-1287.
-
(1994)
J. Cell Biol
, vol.125
, pp. 1275-1287
-
-
Rando, T.A.1
Blau, H.M.2
-
50
-
-
0034175632
-
Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice
-
Rudolph, D., W.C. Yeh, A. Wakeham, B. Rudolph, D. Nallainathan, J. Potter, A.J. Elia, and T.W. Mak. 2000. Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice. Genes Dev. 14:854-862.
-
(2000)
Genes Dev
, vol.14
, pp. 854-862
-
-
Rudolph, D.1
Yeh, W.C.2
Wakeham, A.3
Rudolph, B.4
Nallainathan, D.5
Potter, J.6
Elia, A.J.7
Mak, T.W.8
-
51
-
-
19344374949
-
IκB kinase (IKK)β, but not IKKα, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss
-
Ruocco, M.G., S. Maeda, J.M. Park, T. Lawrence, L.C. Hsu, Y. Cao, G. Schett, E.F. Wagner, and M. Karin. 2005. IκB kinase (IKK)β, but not IKKα, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss. J. Exp. Med. 201:1677-1687.
-
(2005)
J. Exp. Med
, vol.201
, pp. 1677-1687
-
-
Ruocco, M.G.1
Maeda, S.2
Park, J.M.3
Lawrence, T.4
Hsu, L.C.5
Cao, Y.6
Schett, G.7
Wagner, E.F.8
Karin, M.9
-
52
-
-
0033952368
-
The molecular regulation of myogenesis
-
Sabourin, L.A., and M.A. Rudnicki. 2000. The molecular regulation of myogenesis. Clin. Genet. 57:16-25.
-
(2000)
Clin. Genet
, vol.57
, pp. 16-25
-
-
Sabourin, L.A.1
Rudnicki, M.A.2
-
53
-
-
0033593785
-
Reduced differentiation potential of primary MyoD-/- myogenic cells derived from adult skeletal muscle
-
Sabourin, L.A., A. Girgis-Gabardo, P. Seale, A. Asakura, and M.A. Rudnicki. 1999. Reduced differentiation potential of primary MyoD-/- myogenic cells derived from adult skeletal muscle. J. Cell Biol. 144:631-643.
-
(1999)
J. Cell Biol
, vol.144
, pp. 631-643
-
-
Sabourin, L.A.1
Girgis-Gabardo, A.2
Seale, P.3
Asakura, A.4
Rudnicki, M.A.5
-
54
-
-
0028116117
-
Structural and functional analysis of the NF-kappa B p65 C terminus. An acidic and modular transactivation domain with the potential to adopt an alpha-helical conformation
-
Schmitz, M.L., M.A. dos Santos Silva, H. Altmann, M. Czisch, T.A. Holak, and P.A. Baeuerle. 1994. Structural and functional analysis of the NF-kappa B p65 C terminus. An acidic and modular transactivation domain with the potential to adopt an alpha-helical conformation. J. Biol. Chem. 269:25613-25620.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 25613-25620
-
-
Schmitz, M.L.1
dos Santos Silva, M.A.2
Altmann, H.3
Czisch, M.4
Holak, T.A.5
Baeuerle, P.A.6
-
55
-
-
17944378526
-
Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway
-
Senftleben, U., Y. Cao, G. Xiao, F.R. Greten, G. Krahn, G. Bonizzi, Y. Chen, Y. Hu, A. Fong, S.C. Sun, and M. Karin. 2001. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science. 293:1495-1499.
-
(2001)
Science
, vol.293
, pp. 1495-1499
-
-
Senftleben, U.1
Cao, Y.2
Xiao, G.3
Greten, F.R.4
Krahn, G.5
Bonizzi, G.6
Chen, Y.7
Hu, Y.8
Fong, A.9
Sun, S.C.10
Karin, M.11
-
56
-
-
1942484963
-
IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis
-
Sil, A.K., S. Maeda, Y. Sano, D.R. Roop, and M. Karin. 2004. IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis. Nature. 428:660-664.
-
(2004)
Nature
, vol.428
, pp. 660-664
-
-
Sil, A.K.1
Maeda, S.2
Sano, Y.3
Roop, D.R.4
Karin, M.5
-
57
-
-
0141780826
-
NF-kappaB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism
-
Sitcheran, R., P.C. Cogswell, and A.S. Baldwin Jr. 2003. NF-kappaB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism. Genes Dev. 17:2368-2373.
-
(2003)
Genes Dev
, vol.17
, pp. 2368-2373
-
-
Sitcheran, R.1
Cogswell, P.C.2
Baldwin Jr., A.S.3
-
58
-
-
0033537757
-
Limb and skin abnormalities in mice lacking IKKalpha
-
Takeda, K., O. Takeuchi, T. Tsujimura, S. Itami, O. Adachi, T. Kawai, H. Sanjo, K. Yoshikawa, N. Terada, and S. Akira. 1999. Limb and skin abnormalities in mice lacking IKKalpha. Science. 284:313-316.
-
(1999)
Science
, vol.284
, pp. 313-316
-
-
Takeda, K.1
Takeuchi, O.2
Tsujimura, T.3
Itami, S.4
Adachi, O.5
Kawai, T.6
Sanjo, H.7
Yoshikawa, K.8
Terada, N.9
Akira, S.10
-
59
-
-
0033119952
-
Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice
-
Tanaka, M., M.E. Fuentes, K. Yamaguchi, M.H. Durnin, S.A. Dalrymple, K.L. Hardy, and D.V. Goeddel. 1999. Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice. Immunity. 10:421-429.
-
(1999)
Immunity
, vol.10
, pp. 421-429
-
-
Tanaka, M.1
Fuentes, M.E.2
Yamaguchi, K.3
Durnin, M.H.4
Dalrymple, S.A.5
Hardy, K.L.6
Goeddel, D.V.7
-
60
-
-
34250218193
-
NF-kappaB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes
-
Wang, H., E. Hertlein, N. Bakkar, H. Sun, S. Acharyya, J. Wang, M. Carathers, R. Davuluri, and D.C. Guttridge. 2007. NF-kappaB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes. Mol. Cell. Biol. 27:4374-4387.
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 4374-4387
-
-
Wang, H.1
Hertlein, E.2
Bakkar, N.3
Sun, H.4
Acharyya, S.5
Wang, J.6
Carathers, M.7
Davuluri, R.8
Guttridge, D.C.9
-
61
-
-
0030292678
-
Both multiorgan inflammation and myeloid hyperplasia in RelB-deficient mice are T cell dependent
-
Weih, F., S.K. Durham, D.S. Barton, W.C. Sha, D. Baltimore, and R. Bravo. 1996. Both multiorgan inflammation and myeloid hyperplasia in RelB-deficient mice are T cell dependent. J. Immunol. 157:3974-3979.
-
(1996)
J. Immunol
, vol.157
, pp. 3974-3979
-
-
Weih, F.1
Durham, S.K.2
Barton, D.S.3
Sha, W.C.4
Baltimore, D.5
Bravo, R.6
-
62
-
-
0034745420
-
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100
-
Xiao, G., E.W. Harhaj, and S.C. Sun. 2001. NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol. Cell. 7:401-409.
-
(2001)
Mol. Cell
, vol.7
, pp. 401-409
-
-
Xiao, G.1
Harhaj, E.W.2
Sun, S.C.3
-
63
-
-
0038511129
-
Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression
-
Yamamoto, Y., U.N. Verma, S. Prajapati, Y.T. Kwak, and R.B. Gaynor. 2003. Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression. Nature. 423:655-659.
-
(2003)
Nature
, vol.423
, pp. 655-659
-
-
Yamamoto, Y.1
Verma, U.N.2
Prajapati, S.3
Kwak, Y.T.4
Gaynor, R.B.5
-
64
-
-
0032039076
-
Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
-
Zhong, H., R.E. Voll, and S. Ghosh. 1998. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol. Cell. 1:661-671.
-
(1998)
Mol. Cell
, vol.1
, pp. 661-671
-
-
Zhong, H.1
Voll, R.E.2
Ghosh, S.3
|