Neuronal inactivation of peroxisome proliferator-activated receptor γ coactivator 1α(PGC-1α) protects mice from diet-induced obesity and leads to degenerative lesions

Journal of Biological Chemistry

Volumn 285, Issue 50, 2010, Pages 39087-39095

  Ma, Di ^a   Li, Siming ^a   Lucas, Elizabeth K ^b   Cowell, Rita M ^b   Lin, Jiandie D ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II; CENTRAL NERVOUS SYSTEMS; COACTIVATORS; COLD EXPOSURE; DIET-INDUCED OBESITY; ENERGY EXPENDITURE; ENERGY METABOLISM; IN-VIVO; KNOCK OUTS; METABOLIC PROFILES; METABOLIC RATES; NEURODEGENERATION; NEURONAL FUNCTION; PERIPHERAL TISSUE; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; TRANSCRIPTIONAL CO-ACTIVATORS; WHOLE BODY;

CYTOLOGY; ELECTROPHYSIOLOGY; ENERGY BALANCE; GENE EXPRESSION; HISTOLOGY; METABOLISM; NUTRITION; TISSUE;

GENE EXPRESSION REGULATION;

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IIALPHA; CRE RECOMBINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROOPIOMELANOCORTIN; PROPROTEIN CONVERTASE 2; PROTIRELIN; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENERGY BALANCE; ENERGY METABOLISM; FEMALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; THERMOGENESIS; TRANSCRIPTION REGULATION; TRANSGENE;

ANIMAL FEED; ANIMALS; BRAIN; CONSTRICTION, PATHOLOGIC; GENE EXPRESSION REGULATION; LIVER; MICE; MICE, TRANSGENIC; NEURODEGENERATIVE DISEASES; NEURONS; OBESITY; OXYGEN CONSUMPTION; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRIGLYCERIDES;

MUS;

EID: 78649819597     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.151688     Document Type: Article

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