FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

Genes and Development

Volumn 26, Issue 3, 2012, Pages 271-281

  Fisher, Ffolliott ^a   Kleiner, Sandra ^a   Douris, Nicholas ^a   Fox, Elliott C ^a   Mepani, Rina J ^a   Verdeguer, Francisco ^a   Wu, Jun ^a   Kharitonenkov, Alexei ^b   Flier, Jeffrey S ^a   Maratos Flier, Eleftheria ^a   Spiegelman, Bruce M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

Adipose tissue; FGf21; PGC 1 ; Thermogenesis

Indexed keywords

FIBROBLAST GROWTH FACTOR 21; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; UNCOUPLING PROTEIN 1;

ADAPTATION; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; COLD EXPOSURE; CONTROLLED STUDY; GENE EXPRESSION; HYPOTHERMIA; IN VIVO STUDY; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; THERMOGENESIS; WHITE ADIPOSE TISSUE;

ADAPTATION, PHYSIOLOGICAL; ADIPOSE TISSUE, BROWN; ADIPOSE TISSUE, WHITE; ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; COLD TEMPERATURE; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; MALE; MICE; MICE, INBRED C57BL; RNA PROCESSING, POST-TRANSCRIPTIONAL; THERMOGENESIS; TRANS-ACTIVATORS;

MUS;

EID: 84863012022     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.177857.111     Document Type: Article

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