Hypomorphic mutation of PGC-1β causes mitochondrial dysfunction and liver insulin resistance

Cell Metabolism

Volumn 4, Issue 6, 2006, Pages 453-464

  Vianna, Claudia R ^a   Huntgeburth, Michael ^a,b   Coppari, Roberto ^a   Choi, Cheol Soo ^c   Lin, Jiandie ^d   Krauss, Stefan ^a   Barbatelli, Giorgio ^e   Tzameli, Iphigenia ^a   Kim, Young Bum ^a   Cinti, Saverio ^e   Shulman, Gerald I ^c   Spiegelman, Bruce M ^d   Lowell, Bradford B ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e University of Marche   (Italy)

Author keywords

HUMDISEASE

Indexed keywords

INSULIN; MUTANT PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EXON; GENE MUTATION; HYPERINSULINEMIA; INSULIN RESISTANCE; MALE; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

ANIMALS; GENE EXPRESSION REGULATION; GLUCOSE CLAMP TECHNIQUE; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; LIVER; MICE; MICE, KNOCKOUT; MITOCHONDRIA, LIVER; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; MUTATION; ORGAN SPECIFICITY; RECEPTORS, ESTROGEN; TRANS-ACTIVATORS;

EID: 33751400561     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2006.11.003     Document Type: Article

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