-
1
-
-
70349991886
-
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
-
Alegre-Abarrategui J, Christian H, Lufino MM, Mutihac R, Venda LL, AnsorgeO, Wade-Martins R. 2009. LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model. Hum Mol Genet 18: 4022-4034.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4022-4034
-
-
Alegre-Abarrategui, J.1
Christian, H.2
Lufino, M.M.3
Mutihac, R.4
Venda, L.L.5
Ansorge, O.6
Wade-Martins, R.7
-
2
-
-
73449124773
-
Parkinson disease, LRRK2 and the endocytic-autophagic pathway
-
Alegre-Abarrategui J, Wade-Martins R. 2009. Parkinson disease, LRRK2 and the endocytic-autophagic pathway. Autophagy 5: 1208-1210.
-
(2009)
Autophagy
, vol.5
, pp. 1208-1210
-
-
Alegre-Abarrategui, J.1
Wade-Martins, R.2
-
3
-
-
0037185004
-
α-synuclein lowers p53-dependent apoptotic response of neuronal cells. Abolishment by 6-hydroxydopamine and implication for Parkinson's disease
-
Alves Da Costa C, Paitel E, Vincent B, Checler F. 2002. α-synuclein lowers p53-dependent apoptotic response of neuronal cells. Abolishment by 6-hydroxydopamine and implication for Parkinson's disease. J Biol Chem 277:50980-50984.
-
(2002)
J Biol Chem
, vol.277
, pp. 50980-50984
-
-
Da Costa Alves, C.1
Paitel, E.2
Vincent, B.3
Checler, F.4
-
4
-
-
57649233085
-
P53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism
-
Andrabi SA, Dawson TM, Dawson VL. 2008. p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism. Ann NY Acad Sci 1147: 233-241.
-
(2008)
Ann NY Acad Sci
, vol.1147
, pp. 233-241
-
-
Andrabi, S.A.1
Dawson, T.M.2
Dawson, V.L.3
-
5
-
-
0031036896
-
Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease
-
Anglade P, Vyas S, Javoy-Agid F, Herrero MT, Michel PP, Marquez J, Mouatt-Prigent A, Ruberg M, Hirsch EC, Agid Y. 1997. Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease. Histol Histopathol 12: 25-31.
-
(1997)
Histol Histopathol
, vol.12
, pp. 25-31
-
-
Anglade, P.1
Vyas, S.2
Javoy-Agid, F.3
Herrero, M.T.4
Michel, P.P.5
Marquez, J.6
Mouatt-Prigent, A.7
Ruberg, M.8
Hirsch, E.C.9
Agid, Y.10
-
6
-
-
34250344611
-
Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation
-
Avraham E, Rott R, Liani E, Szargel R, Engelender S. 2007. Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation. J Biol Chem 282: 12842-12850.
-
(2007)
J Biol Chem
, vol.282
, pp. 12842-12850
-
-
Avraham, E.1
Rott, R.2
Liani, E.3
Szargel, R.4
Engelender, S.5
-
7
-
-
84856770468
-
Role of the mitochondrion in programmed necrosis
-
Baines CP. 2010. Role of the mitochondrion in programmed necrosis. Front Physiol 1: 156.
-
(2010)
Front Physiol
, vol.1
, pp. 156
-
-
Baines, C.P.1
-
8
-
-
0031930771
-
Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease
-
Banati RB, Daniel SE, Blunt SB. 1998. Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease. Mov Disord 13: 221-227.
-
(1998)
Mov Disord
, vol.13
, pp. 221-227
-
-
Banati, R.B.1
Daniel, S.E.2
Blunt, S.B.3
-
9
-
-
33748028841
-
Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons
-
Barsoum MJ, Yuan H, Gerencser AA, Liot G, Kushnareva Y, Graber S, Kovacs I, Lee WD, Waggoner J, Cui J, et al. 2006. Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. EMBO J 25:3900-3911.
-
(2006)
EMBO J
, vol.25
, pp. 3900-3911
-
-
Barsoum, M.J.1
Yuan, H.2
Gerencser, A.A.3
Liot, G.4
Kushnareva, Y.5
Graber, S.6
Kovacs, I.7
Lee, W.D.8
Waggoner, J.9
Cui, J.10
-
10
-
-
79551647443
-
Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson's disease
-
Bellucci A, Navarria L, Zaltieri M, Falarti E, Bodei S, Sigala S, Battistin L, Spillantini M, Missale C, Spano P. 2011. Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson's disease. J Neurochem 116: 588-605.
-
(2011)
J Neurochem
, vol.116
, pp. 588-605
-
-
Bellucci, A.1
Navarria, L.2
Zaltieri, M.3
Falarti, E.4
Bodei, S.5
Sigala, S.6
Battistin, L.7
Spillantini, M.8
Missale, C.9
Spano, P.10
-
11
-
-
70350689923
-
Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release
-
Berger AK, Cortese GP, Amodeo KD, Weihofen A, Letai A, LaVoie MJ. 2009. Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release. Human Mol Genet 18: 4317-4328.
-
(2009)
Human Mol Genet
, vol.18
, pp. 4317-4328
-
-
Berger, A.K.1
Cortese, G.P.2
Amodeo, K.D.3
Weihofen, A.4
Letai, A.5
LaVoie, M.J.6
-
12
-
-
0036549215
-
Caspase inhibitors attenuate 1-methyl-4-phenylpyridinium toxicity in primary cultures of mesencephalic dopaminergic neurons
-
Bilsland J, Roy S, Xanthoudakis S, Nicholson DW, Han Y, Grimm E, Hefti F, Harper SJ. 2002. Caspase inhibitors attenuate 1-methyl-4-phenylpyridinium toxicity in primary cultures of mesencephalic dopaminergic neurons. J Neurosci 22: 2637-2649.
-
(2002)
J Neurosci
, vol.22
, pp. 2637-2649
-
-
Bilsland, J.1
Roy, S.2
Xanthoudakis, S.3
Nicholson, D.W.4
Han, Y.5
Grimm, E.6
Hefti, F.7
Harper, S.J.8
-
13
-
-
0030956532
-
P53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PC12 cells
-
Blum D, Wu Y, Nissou MF, Arnaud S, Alim Louis B, Verna JM. 1997. p53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PC12 cells. Brain Res 751: 139-142.
-
(1997)
Brain Res
, vol.751
, pp. 139-142
-
-
Blum, D.1
Wu, Y.2
Nissou, M.F.3
Arnaud, S.4
Alim Louis, B.5
Verna, J.M.6
-
14
-
-
0028364696
-
Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease
-
Boka G, Anglade P, Wallach D, Javoy-Agid F, Agid Y, Hirsch EC. 1994. Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease. Neurosci Lett 172: 151-154.
-
(1994)
Neurosci Lett
, vol.172
, pp. 151-154
-
-
Boka, G.1
Anglade, P.2
Wallach, D.3
Javoy-Agid, F.4
Agid, Y.5
Hirsch, E.C.6
-
15
-
-
0344413426
-
Mitochondrial fission in apoptosis, neurodegeneration and aging
-
Bossy-Wetzel E, Barsoum MJ, Godzik A, Schwarzenbacher R, Lipton SA. 2003. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol 15: 706-716.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 706-716
-
-
Bossy-Wetzel, E.1
Barsoum, M.J.2
Godzik, A.3
Schwarzenbacher, R.4
Lipton, S.A.5
-
16
-
-
79954417075
-
Parkin is transcriptionally regulated by ATF4: Evidence for an interconnection between mitochondrial stress and ER stress
-
Bouman L, Schlierf A, Lutz AK, Shan J, Deinlein A, Kast J, Galehdar Z, PalmisanoV, Patenge N, Berg D, et al. 2011. Parkin is transcriptionally regulated by ATF4: Evidence for an interconnection between mitochondrial stress and ER stress. Cell Death Differ 18: 769-782.
-
(2011)
Cell Death Differ
, vol.18
, pp. 769-782
-
-
Bouman, L.1
Schlierf, A.2
Lutz, A.K.3
Shan, J.4
Deinlein, A.5
Kast, J.6
Galehdar, Z.7
Palmisano, V.8
Patenge, N.9
Berg, D.10
-
17
-
-
19944434059
-
Inhibition of macroautophagy triggers apoptosis
-
Boya P, Gonzalez-Polo RA, Casares N, Perfettini JL, Dessen P, Larochette N, Metivier D, Meley D, Souquere S, Yoshimori T, et al. 2005. Inhibition of macroautophagy triggers apoptosis. Molec Cell Biol 25: 1025-1040.
-
(2005)
Molec Cell Biol
, vol.25
, pp. 1025-1040
-
-
Boya, P.1
Gonzalez-Polo, R.A.2
Casares, N.3
Perfettini, J.L.4
Dessen, P.5
Larochette, N.6
Metivier, D.7
Meley, D.8
Souquere, S.9
Yoshimori, T.10
-
18
-
-
33750292972
-
Cell death in the nervous system
-
Bredesen DE, Rao RV, Mehlen P. 2006. Cell death in the nervous system. Nature 443: 796-802.
-
(2006)
Nature
, vol.443
, pp. 796-802
-
-
Bredesen, D.E.1
Rao, R.V.2
Mehlen, P.3
-
19
-
-
33847723997
-
P53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease
-
Bretaud S, Allen C, Ingham PW, Bandmann O. 2007. p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease. J Neurochem 100: 1626-1635.
-
(2007)
J Neurochem
, vol.100
, pp. 1626-1635
-
-
Bretaud, S.1
Allen, C.2
Ingham, P.W.3
Bandmann, O.4
-
20
-
-
0028828550
-
Cortical and brainstem-type Lewy bodies are immunoreactive for the cyclin-dependent kinase 5
-
Brion JP, Couck AM. 1995. Cortical and brainstem-type Lewy bodies are immunoreactive for the cyclin-dependent kinase 5. Am J Pathol 147:1465-1476.
-
(1995)
Am J Pathol
, vol.147
, pp. 1465-1476
-
-
Brion, J.P.1
Couck, A.M.2
-
21
-
-
34547442346
-
Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins
-
Brooks C, Wei Q, Feng L, Dong G, Tao Y, Mei L, Xie ZJ, Dong Z. 2007. Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins. Proc Natl Acad Sci 104: 11649-11654.
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 11649-11654
-
-
Brooks, C.1
Wei, Q.2
Feng, L.3
Dong, G.4
Tao, Y.5
Mei, L.6
Xie, Z.J.7
Dong, Z.8
-
22
-
-
0026324174
-
Ascorbic acid enhances the effects of 6-hydroxydopamine and H2O2 on iron-dependent DNA strand breaks and related processes in the neuroblastoma cell line SK-N-SH
-
Bruchelt G, Schraufstatter IU, Niethammer D, Cochrane CG. 1991. Ascorbic acid enhances the effects of 6-hydroxydopamine and H2O2 on iron-dependent DNA strand breaks and related processes in the neuroblastoma cell line SK-N-SH. Cancer Res 51: 6066-6072.
-
(1991)
Cancer Res
, vol.51
, pp. 6066-6072
-
-
Bruchelt, G.1
Schraufstatter, I.U.2
Niethammer, D.3
Cochrane, C.G.4
-
23
-
-
0035369623
-
Transcription-dependent and-independent control of neuronal survival by the PI3K-Akt signaling pathway
-
Brunet A, Datta SR, Greenberg ME. 2001. Transcription-dependent and-independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr Opin Neurobiol 11: 297-305.
-
(2001)
Curr Opin Neurobiol
, vol.11
, pp. 297-305
-
-
Brunet, A.1
Datta, S.R.2
Greenberg, M.E.3
-
24
-
-
78349304719
-
Apoptosis-inducing factor mediates dopaminergic cell death in response to LPS-induced inflammatory stimulus: Evidence in Parkinson's disease patients
-
Burguillos MA, Hajji N, Englund E, Persson A, Cenci AM, Machado A, Cano J, Joseph B, Venero JL. 2011. Apoptosis-inducing factor mediates dopaminergic cell death in response to LPS-induced inflammatory stimulus: Evidence in Parkinson's disease patients. Neurobiol Dis 41: 177-188.
-
(2011)
Neurobiol Dis
, vol.41
, pp. 177-188
-
-
Burguillos, M.A.1
Hajji, N.2
Englund, E.3
Persson, A.4
Cenci, A.M.5
McHado, A.6
Cano, J.7
Joseph, B.8
Venero, J.L.9
-
25
-
-
38449107680
-
Programmed cell death and new discoveries in the genetics of parkinsonism
-
Burke RE. 2008. Programmed cell death and new discoveries in the genetics of parkinsonism. J Neurochem 104: 875-890.
-
(2008)
J Neurochem
, vol.104
, pp. 875-890
-
-
Burke, R.E.1
-
26
-
-
77955370958
-
Intracellular signalling pathways in dopamine cell death and axonal degeneration
-
Burke RE. 2010. Intracellular signalling pathways in dopamine cell death and axonal degeneration. Prog Brain Res 183: 79-97.
-
(2010)
Prog Brain Res
, vol.183
, pp. 79-97
-
-
Burke, R.E.1
-
27
-
-
33748087835
-
Involvement of calpain activation in neurodegenerative processes
-
Camins A, Verdaguer E, Folch J, Pallas M. 2006. Involvement of calpain activation in neurodegenerative processes. CNS Drug Rev 12: 135-148.
-
(2006)
CNS Drug Rev
, vol.12
, pp. 135-148
-
-
Camins, A.1
Verdaguer, E.2
Folch, J.3
Pallas, M.4
-
28
-
-
2942684871
-
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
Canet-Aviles RM, Wilson MA, Miller DW, Ahmad R, McLendon C, Bandyopadhyay S, Baptista MJ, Ringe D, Petsko GA, Cookson MR. 2004. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc Natl Acad Sci 101: 9103-9108.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
Bandyopadhyay, S.6
Baptista, M.J.7
Ringe, D.8
Petsko, G.A.9
Cookson, M.R.10
-
29
-
-
33646114508
-
Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline
-
Casarejos MJ, Menendez J, Solano RM, Rodriguez-Navarro JA, Garcia de Yebenes J, Mena MA. 2006. Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline. J Neurochem 97: 934-946.
-
(2006)
J Neurochem
, vol.97
, pp. 934-946
-
-
Casarejos, M.J.1
Menendez, J.2
Solano, R.M.3
Rodriguez-Navarro, J.A.4
de Yebenes Garcia, J.5
Mena, M.A.6
-
30
-
-
22544458436
-
Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila
-
Cha GH, Kim S, Park J, Lee E, Kim M, Lee SB, Kim JM, Chung J, Cho KS. 2005. Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila. Proc Natl Acad Sci 102: 10345-10350.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 10345-10350
-
-
Cha, G.H.1
Kim, S.2
Park, J.3
Lee, E.4
Kim, M.5
Lee, S.B.6
Kim, J.M.7
Chung, J.8
Cho, K.S.9
-
31
-
-
33745274726
-
Mitochondria: Dynamic organelles in disease, aging, and development
-
Chan DC. 2006. Mitochondria: Dynamic organelles in disease, aging, and development. Cell 125: 1241-1252.
-
(2006)
Cell
, vol.125
, pp. 1241-1252
-
-
Chan, D.C.1
-
32
-
-
0033232529
-
Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: Evidence that GAPDH is upregulated by p53
-
Chen RW, Saunders PA, Wei H, Li Z, Seth P, Chuang DM. 1999. Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: Evidence that GAPDH is upregulated by p53. J Neurosci 19:9654-9662.
-
(1999)
J Neurosci
, vol.19
, pp. 9654-9662
-
-
Chen, R.W.1
Saunders, P.A.2
Wei, H.3
Li, Z.4
Seth, P.5
Chuang, D.M.6
-
33
-
-
9444257518
-
Glycogen synthase kinase 3β (GSK3β) mediates 6-hydroxydopamine-induced neuronal death
-
Chen G, Bower KA, Ma C, Fang S, Thiele CJ, Luo J. 2004. Glycogen synthase kinase 3β (GSK3β) mediates 6-hydroxydopamine-induced neuronal death. FASEB J 18: 1162-1164.
-
(2004)
FASEB J
, vol.18
, pp. 1162-1164
-
-
Chen, G.1
Bower, K.A.2
Ma, C.3
Fang, S.4
Thiele, C.J.5
Luo, J.6
-
34
-
-
33644745300
-
Early induction of calpains in rotenone-mediated neuronal apoptosis
-
Chen MJ, Yap YW, Choy MS, Koh CH, Seet SJ, Duan W, Whiteman M, Cheung NS.2006. Early induction of calpains in rotenone-mediated neuronal apoptosis. Neurosci Lett 397: 69-73.
-
(2006)
Neurosci Lett
, vol.397
, pp. 69-73
-
-
Chen, M.J.1
Yap, Y.W.2
Choy, M.S.3
Koh, C.H.4
Seet, S.J.5
Duan, W.6
Whiteman, M.7
Cheung, N.S.8
-
35
-
-
34547601410
-
Mitochondrial fusion protects against neurodegeneration in the cerebellum
-
Chen H, McCaffery JM, Chan DC. 2007. Mitochondrial fusion protects against neurodegeneration in the cerebellum. Cell 130: 548-562.
-
(2007)
Cell
, vol.130
, pp. 548-562
-
-
Chen, H.1
McCaffery, J.M.2
Chan, D.C.3
-
36
-
-
77952683069
-
Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy
-
Chen Y, Lewis W, Diwan A, Cheng EH, Matkovich SJ, Dorn GW 2nd. 2010. Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy. Proc Natl Acad Sci 107: 9035-9042.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 9035-9042
-
-
Chen, Y.1
Lewis, W.2
Diwan, A.3
Cheng, E.H.4
Matkovich, S.J.5
Dorn II, G.W.6
-
37
-
-
79951531959
-
Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy
-
Cheng HC, Kim SR, Oo TF, Kareva T, Yarygina O, Rzhetskaya M, Wang C, During M, Talloczy Z, Tanaka K, et al. 2011. Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy. J Neurosci 31: 2125-2135.
-
(2011)
J Neurosci
, vol.31
, pp. 2125-2135
-
-
Cheng, H.C.1
Kim, S.R.2
Oo, T.F.3
Kareva, T.4
Yarygina, O.5
Rzhetskaya, M.6
Wang, C.7
During, M.8
Talloczy, Z.9
Tanaka, K.10
-
38
-
-
84857781607
-
Cdk 5: A multifaceted kinase in neurodegenerative diseases
-
Cheung ZH, Ip NY. 2011. Cdk 5: A multifaceted kinase in neurodegenerative diseases. Trends Cell Biol 22: 169-175.
-
(2011)
Trends Cell Biol
, vol.22
, pp. 169-175
-
-
Cheung, Z.H.1
Ip, N.Y.2
-
39
-
-
24644436766
-
PUMA couples the nuclear and cytoplasmic proapoptotic function of 53
-
Chipuk JE, Bouchier-Hayes L, Kuwana T, Newmeyer DD, Green DR. 2005. PUMA couples the nuclear and cytoplasmic proapoptotic function of 53. Science 309:1732-1735.
-
(2005)
Science
, vol.309
, pp. 1732-1735
-
-
Chipuk, J.E.1
Bouchier-Hayes, L.2
Kuwana, T.3
Newmeyer, D.D.4
Green, D.R.5
-
40
-
-
72849127046
-
A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death
-
Choi KC, Kim SH, Ha JY, Kim ST, Son JH. 2010. A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death. J Neurochem 112: 366-376.
-
(2010)
J Neurochem
, vol.112
, pp. 366-376
-
-
Choi, K.C.1
Kim, S.H.2
Ha, J.Y.3
Kim, S.T.4
Son, J.H.5
-
41
-
-
79953202481
-
Mutant A53T α-synuclein induces neuronal death by increasing mitochondrial autophagy
-
Choubey V, Safiulina D, Vaarmann A, Cagalinec M, Wareski P, Kuum M, Zharkovsky A, Kaasik A. 2011. Mutant A53T α-synuclein induces neuronal death by increasing mitochondrial autophagy. J Biol Chem 286: 10814-10824.
-
(2011)
J Biol Chem
, vol.286
, pp. 10814-10824
-
-
Choubey, V.1
Safiulina, D.2
Vaarmann, A.3
Cagalinec, M.4
Wareski, P.5
Kuum, M.6
Zharkovsky, A.7
Kaasik, A.8
-
42
-
-
79955052386
-
Diversity in the regulation of autophagy and mitophagy: Lessons from Parkinson's disease
-
10.4061/2011/789431
-
Chu CT. 2011. Diversity in the regulation of autophagy and mitophagy: Lessons from Parkinson's disease. Parkinson's Disdoi:10.4061/2011/789431.
-
(2011)
Parkinson's Disdoi
-
-
Chu, C.T.1
-
43
-
-
35848947235
-
Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: Implications for neurodegeneration and cell death
-
Chu CT, Zhu J, Dagda R. 2007. Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: Implications for neurodegeneration and cell death. Autophagy 3: 663-666.
-
(2007)
Autophagy
, vol.3
, pp. 663-666
-
-
Chu, C.T.1
Zhu, J.2
Dagda, R.3
-
44
-
-
0030581308
-
Poly(ADP-ribose) polymerase inhibitors protect against MPTP-induced depletions of striatal dopamine and cortical noradrenaline in C57B1/6 mice
-
Cosi C, Colpaert F, Koek W, Degryse A, Marien M. 1996. Poly(ADP-ribose) polymerase inhibitors protect against MPTP-induced depletions of striatal dopamine and cortical noradrenaline in C57B1/6 mice. Brain Res 729: 264-269.
-
(1996)
Brain Res
, vol.729
, pp. 264-269
-
-
Cosi, C.1
Colpaert, F.2
Koek, W.3
Degryse, A.4
Marien, M.5
-
45
-
-
33745885329
-
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
-
Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, Gasco M, Garrone O, Crook T, Ryan KM. 2006. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 126: 121-134.
-
(2006)
Cell
, vol.126
, pp. 121-134
-
-
Crighton, D.1
Wilkinson, S.2
O'Prey, J.3
Syed, N.4
Smith, P.5
Harrison, P.R.6
Gasco, M.7
Garrone, O.8
Crook, T.9
Ryan, K.M.10
-
46
-
-
0345268775
-
Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice
-
Crocker SJ, Liston P, Anisman H, Lee CJ, Smith PD, Earl N, Thompson CS, ParkDS, Korneluk RG, Robertson GS. 2003a. Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice. Neurobiol Dis 12: 150-161.
-
(2003)
Neurobiol Dis
, vol.12
, pp. 150-161
-
-
Crocker, S.J.1
Liston, P.2
Anisman, H.3
Lee, C.J.4
Smith, P.D.5
Earl, N.6
Thompson, C.S.7
Park, D.S.8
Korneluk, R.G.9
Robertson, G.S.10
-
47
-
-
0038380524
-
Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease
-
Crocker SJ, Smith PD, Jackson-Lewis V, Lamba WR, Hayley SP, Grimm E, Callaghan SM, Slack RS, Melloni E, Przedborski S, et al. 2003b. Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease. J Neurosci 23: 4081-4091.
-
(2003)
J Neurosci
, vol.23
, pp. 4081-4091
-
-
Crocker, S.J.1
Smith, P.D.2
Jackson-Lewis, V.3
Lamba, W.R.4
Hayley, S.P.5
Grimm, E.6
Callaghan, S.M.7
Slack, R.S.8
Melloni, E.9
Przedborski, S.10
-
48
-
-
70449519412
-
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease
-
da Costa CA, Sunyach C, Giaime E, West A, Corti O, Brice A, Safe S, Abou-Sleiman PM, Wood NW, Takahashi H, et al. 2009. Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease. Nature Cell Biol 11: 1370-1375.
-
(2009)
Nature Cell Biol
, vol.11
, pp. 1370-1375
-
-
da Costa, C.A.1
Sunyach, C.2
Giaime, E.3
West, A.4
Corti, O.5
Brice, A.6
Safe, S.7
Abou-Sleiman, P.M.8
Wood, N.W.9
Takahashi, H.10
-
49
-
-
77149132129
-
Autophagy protects the rotenone-induced cell death in α-synuclein overexpressing SH-SY5Y cells
-
Dadakhujaev S, Noh HS, Jung EJ, Cha JY, Baek SM, Ha JH, Kim DR. 2010. Autophagy protects the rotenone-induced cell death in α-synuclein overexpressing SH-SY5Y cells. Neurosci Lett 472: 47-52.
-
(2010)
Neurosci Lett
, vol.472
, pp. 47-52
-
-
Dadakhujaev, S.1
Noh, H.S.2
Jung, E.J.3
Cha, J.Y.4
Baek, S.M.5
Ha, J.H.6
Kim, D.R.7
-
50
-
-
50249168137
-
Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: Implications for Parkinson's disease
-
Dagda RK, Zhu J, Kulich SM, Chu CT. 2008. Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: Implications for Parkinson's disease. Autophagy 4: 770-782.
-
(2008)
Autophagy
, vol.4
, pp. 770-782
-
-
Dagda, R.K.1
Zhu, J.2
Kulich, S.M.3
Chu, C.T.4
-
51
-
-
67649399288
-
Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission
-
Dagda RK, Cherra SJ III., Kulich SM, Tandon A, Park D, Chu CT. 2009. Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. J Biol Chem 284: 13843-13855.
-
(2009)
J Biol Chem
, vol.284
, pp. 13843-13855
-
-
Dagda, R.K.1
Cherra III, S.J.2
Kulich, S.M.3
Tandon, A.4
Park, D.5
Chu, C.T.6
-
52
-
-
0037338634
-
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
-
Darios F, Corti O, Lucking CB, Hampe C, Muriel MP, Abbas N, Gu WJ, HirschEC, Rooney T, Ruberg M, et al. 2003. Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. Human Mol Genet 12: 517-526.
-
(2003)
Human Mol Genet
, vol.12
, pp. 517-526
-
-
Darios, F.1
Corti, O.2
Lucking, C.B.3
Hampe, C.4
Muriel, M.P.5
Abbas, N.6
Gu, W.J.7
Hirsch, E.C.8
Rooney, T.9
Ruberg, M.10
-
53
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
Dauer W, Przedborski S. 2003. Parkinson's disease: Mechanisms and models. Neuron 39: 889-909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
54
-
-
0037240325
-
Rare genetic mutations shed light on the pathogenesis of Parkinson disease
-
Dawson TM, Dawson VL. 2003. Rare genetic mutations shed light on the pathogenesis of Parkinson disease. J Clin Invest 111: 145-151.
-
(2003)
J Clin Invest
, vol.111
, pp. 145-151
-
-
Dawson, T.M.1
Dawson, V.L.2
-
55
-
-
67650638892
-
RIP kinases at the crossroads of cell death and survival
-
Declercq W, Vanden Berghe T, Vandenabeele P. 2009. RIP kinases at the crossroads of cell death and survival. Cell 138: 229-232.
-
(2009)
Cell
, vol.138
, pp. 229-232
-
-
Declercq, W.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
56
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, Cuny GD, Mitchison TJ, Moskowitz MA, Yuan J. 2005. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 1:112-119.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
Li, Y.4
Jagtap, P.5
Mizushima, N.6
Cuny, G.D.7
Mitchison, T.J.8
Moskowitz, M.A.9
Yuan, J.10
-
57
-
-
0031959496
-
P53-and CD95-associated apoptosis in neurodegenerative diseases
-
de la Monte SM, Sohn YK, Ganju N, Wands JR. 1998. P53-and CD95-associated apoptosis in neurodegenerative diseases. Lab Invest 78: 401-411.
-
(1998)
Lab Invest
, vol.78
, pp. 401-411
-
-
de la Monte, S.M.1
Sohn, Y.K.2
Ganju, N.3
Wands, J.R.4
-
58
-
-
27144469287
-
Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y
-
Deng H, Jankovic J, Guo Y, Xie W, Le W. 2005. Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y. Biochem Biophys Res Commun 337: 1133-1138.
-
(2005)
Biochem Biophys Res Commun
, vol.337
, pp. 1133-1138
-
-
Deng, H.1
Jankovic, J.2
Guo, Y.3
Xie, W.4
Le, W.5
-
59
-
-
70449941949
-
Bak activation for apoptosis involves oligomerization of dimers via their α6 helices
-
Dewson G, Kratina T, Czabotar P, Day CL, Adams JM, Kluck RM. 2009. Bak activation for apoptosis involves oligomerization of dimers via their α6 helices. Mol Cell 36: 696-703.
-
(2009)
Mol Cell
, vol.36
, pp. 696-703
-
-
Dewson, G.1
Kratina, T.2
Czabotar, P.3
Day, C.L.4
Adams, J.M.5
Kluck, R.M.6
-
60
-
-
0026345867
-
Apoptosis and DNA degradation induced by 1-methyl-4-phenylpyridinium in neurons
-
Dipasquale B, Marini AM, Youle RJ. 1991. Apoptosis and DNA degradation induced by 1-methyl-4-phenylpyridinium in neurons. Biochem Biophys Res Commun 181: 1442-1448.
-
(1991)
Biochem Biophys Res Commun
, vol.181
, pp. 1442-1448
-
-
Dipasquale, B.1
Marini, A.M.2
Youle, R.J.3
-
61
-
-
33745755472
-
Bcl-2 changes conformation to inhibit Bax oligomerization
-
Dlugosz PJ, Billen LP, Annis MG, Zhu W, Zhang Z, Lin J, Leber B, Andrews DW.2006. Bcl-2 changes conformation to inhibit Bax oligomerization. EMBO J 25:2287-2296.
-
(2006)
EMBO J
, vol.25
, pp. 2287-2296
-
-
Dlugosz, P.J.1
Billen, L.P.2
Annis, M.G.3
Zhu, W.4
Zhang, Z.5
Lin, J.6
Leber, B.7
Andrews, D.W.8
-
62
-
-
0037174934
-
JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery
-
Donovan N, Becker EB, Konishi Y, Bonni A. 2002. JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery. J Biol Chem 277: 40944-40949.
-
(2002)
J Biol Chem
, vol.277
, pp. 40944-40949
-
-
Donovan, N.1
Becker, E.B.2
Konishi, Y.3
Bonni, A.4
-
63
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C, Fang M, Li Y, Li L, Wang X. 2000. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102: 33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
64
-
-
0036829557
-
P53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism
-
Duan W, Zhu X, Ladenheim B, Yu QS, Guo Z, Oyler J, Cutler RG, Cadet JL, GreigNH, Mattson MP. 2002. p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism. Ann Neurol 52: 597-606.
-
(2002)
Ann Neurol
, vol.52
, pp. 597-606
-
-
Duan, W.1
Zhu, X.2
Ladenheim, B.3
Yu, Q.S.4
Guo, Z.5
Oyler, J.6
Cutler, R.G.7
Cadet, J.L.8
Greig, N.H.9
Mattson, M.P.10
-
65
-
-
0030915587
-
Intracellular ATP levels determine cell death fate by apoptosis or necrosis
-
Eguchi Y, Shimizu S, Tsujimoto Y. 1997. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res 57: 1835-1840.
-
(1997)
Cancer Res
, vol.57
, pp. 1835-1840
-
-
Eguchi, Y.1
Shimizu, S.2
Tsujimoto, Y.3
-
66
-
-
20444426695
-
Apoptosis: A key in neurodegenerative disorders
-
Ekshyyan O, Aw TY. 2004. Apoptosis: A key in neurodegenerative disorders. Curr Neurovasc Res 1: 355-371.
-
(2004)
Curr Neurovasc Res
, vol.1
, pp. 355-371
-
-
Ekshyyan, O.1
Aw, T.Y.2
-
67
-
-
34250308322
-
Apoptosis: A review of programmed cell death
-
Elmore S. 2007. Apoptosis: A review of programmed cell death. Toxicol Pathol 35: 495-516.
-
(2007)
Toxicol Pathol
, vol.35
, pp. 495-516
-
-
Elmore, S.1
-
68
-
-
33746594215
-
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling
-
Fallon L, Belanger CM, Corera AT, Kontogiannea M, Regan-Klapisz E, Moreau F, Voortman J, Haber M, Rouleau G, Thorarinsdottir T, et al. 2006. A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling. Nat Cell Biol 8: 834-842.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 834-842
-
-
Fallon, L.1
Belanger, C.M.2
Corera, A.T.3
Kontogiannea, M.4
Regan-Klapisz, E.5
Moreau, F.6
Voortman, J.7
Haber, M.8
Rouleau, G.9
Thorarinsdottir, T.10
-
69
-
-
40849138195
-
DJ-1 decreases Bax expression through repressing p53 transcriptional activity
-
Fan J, Ren H, Jia N, Fei E, Zhou T, Jiang P, Wu M, Wang G. 2008. DJ-1 decreases Bax expression through repressing p53 transcriptional activity. J Biol Chem 283:4022-4030.
-
(2008)
J Biol Chem
, vol.283
, pp. 4022-4030
-
-
Fan, J.1
Ren, H.2
Jia, N.3
Fei, E.4
Zhou, T.5
Jiang, P.6
Wu, M.7
Wang, G.8
-
70
-
-
41249098254
-
Paraquat neurotoxicity is mediated by a Bak-dependent mechanism
-
Fei Q, McCormack AL, Di Monte DA, Ethell DW. 2008. Paraquat neurotoxicity is mediated by a Bak-dependent mechanism. J Biol Chem 283: 3357-3364.
-
(2008)
J Biol Chem
, vol.283
, pp. 3357-3364
-
-
Fei, Q.1
McCormack, A.L.2
Di Monte, D.A.3
Ethell, D.W.4
-
71
-
-
20444363122
-
The coordinate regulation of the p53 and mTOR pathways in cells
-
Feng Z, Zhang H, Levine AJ, Jin S. 2005. The coordinate regulation of the p53 and mTOR pathways in cells. Proc Natl Acad Sci 102: 8204-8209.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 8204-8209
-
-
Feng, Z.1
Zhang, H.2
Levine, A.J.3
Jin, S.4
-
72
-
-
0035487808
-
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
-
Frank S, Gaume B, Bergmann-Leitner ES, Leitner WW, Robert EG, Catez F, SmithCL, Youle RJ. 2001. The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev Cell 1: 515-525.
-
(2001)
Dev Cell
, vol.1
, pp. 515-525
-
-
Frank, S.1
Gaume, B.2
Bergmann-Leitner, E.S.3
Leitner, W.W.4
Robert, E.G.5
Catez, F.6
Smith, C.L.7
Youle, R.J.8
-
73
-
-
84858007356
-
DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADD
-
Fu K, Ren H, Wang Y, Fei E, Wang H, Wang G. 2011. DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADD. Oncogene 31: 1311-1322.
-
(2011)
Oncogene
, vol.31
, pp. 1311-1322
-
-
Fu, K.1
Ren, H.2
Wang, Y.3
Fei, E.4
Wang, H.5
Wang, G.6
-
74
-
-
10644282148
-
The protein structures that shape caspase activity, specificity, activation and inhibition
-
Fuentes-Prior P, Salvesen GS. 2004. The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem J 384: 201-232.
-
(2004)
Biochem J
, vol.384
, pp. 201-232
-
-
Fuentes-Prior, P.1
Salvesen, G.S.2
-
75
-
-
57649167477
-
Necroptosis: A specialized pathway of programmed necrosis
-
Galluzzi L, Kroemer G. 2008. Necroptosis: A specialized pathway of programmed necrosis. Cell 135: 1161-1163.
-
(2008)
Cell
, vol.135
, pp. 1161-1163
-
-
Galluzzi, L.1
Kroemer, G.2
-
76
-
-
61649088435
-
PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death
-
Gandhi S, Wood-Kaczmar A, Yao Z, Plun-Favreau H, Deas E, Klupsch K, Downward J, Latchman DS, Tabrizi SJ, Wood NW, et al. 2009. PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. Mol Cell 33: 627-638.
-
(2009)
Mol Cell
, vol.33
, pp. 627-638
-
-
Gandhi, S.1
Wood-Kaczmar, A.2
Yao, Z.3
Plun-Favreau, H.4
Deas, E.5
Klupsch, K.6
Downward, J.7
Latchman, D.S.8
Tabrizi, S.J.9
Wood, N.W.10
-
77
-
-
78649463381
-
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
-
Gegg ME, Cooper JM, Chau KY, Rojo M, Schapira AH, Taanman JW. 2010. Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum Mol Genet 19: 4861-4870.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4861-4870
-
-
Gegg, M.E.1
Cooper, J.M.2
Chau, K.Y.3
Rojo, M.4
Schapira, A.H.5
Taanman, J.W.6
-
78
-
-
0242693282
-
MPP+ induces the endoplasmic reticulum stress response in rabbit brain involving activation of the ATF-6 and NF-kappaB signaling pathways
-
Ghribi O, Herman MM, Pramoonjago P, Savory J. 2003. MPP+ induces the endoplasmic reticulum stress response in rabbit brain involving activation of the ATF-6 and NF-kappaB signaling pathways. J Neuropathol Exp Neurol 62:1144-1153.
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, pp. 1144-1153
-
-
Ghribi, O.1
Herman, M.M.2
Pramoonjago, P.3
Savory, J.4
-
79
-
-
39849090617
-
6-Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK-mediated, p53-independent activation of Bax and PUMA
-
Gomez-Lazaro M, Galindo MF, Concannon CG, Segura MF, Fernandez-GomezFJ, Llecha N, Comella JX, Prehn JH, Jordan J. 2008. 6-Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK-mediated, p53-independent activation of Bax and PUMA. J Neurochem 104: 1599-1612.
-
(2008)
J Neurochem
, vol.104
, pp. 1599-1612
-
-
Gomez-Lazaro, M.1
Galindo, M.F.2
Concannon, C.G.3
Segura, M.F.4
Fernandez-Gomez, F.J.5
Llecha, N.6
Comella, J.X.7
Prehn, J.H.8
Jordan, J.9
-
80
-
-
84862907943
-
Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP
-
Gomez-Suaga P, Luzon-Toro B, Churamani D, Zhang L, Bloor-Young D, PatelS, Woodman PG, Churchill GC, Hilfiker S. 2012. Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP. Hum Mol Genet 21: 511-525.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 511-525
-
-
Gomez-Suaga, P.1
Luzon-Toro, B.2
Churamani, D.3
Zhang, L.4
Bloor-Young, D.5
Patel, S.6
Woodman, P.G.7
Churchill, G.C.8
Hilfiker, S.9
-
81
-
-
23844483152
-
The apoptosis/autophagy paradox: Autophagic vacuolization before apoptotic death
-
Gonzalez-Polo RA, Boya P, Pauleau AL, Jalil A, Larochette N, Souquere S, Eskelinen EL, Pierron G, Saftig P, Kroemer G. 2005. The apoptosis/autophagy paradox: Autophagic vacuolization before apoptotic death. J Cell Sci 118:3091-3102.
-
(2005)
J Cell Sci
, vol.118
, pp. 3091-3102
-
-
Gonzalez-Polo, R.A.1
Boya, P.2
Pauleau, A.L.3
Jalil, A.4
Larochette, N.5
Souquere, S.6
Eskelinen, E.L.7
Pierron, G.8
Saftig, P.9
Kroemer, G.10
-
82
-
-
64149091391
-
Silencing DJ-1 reveals its contribution in paraquat-induced autophagy
-
Gonzalez-Polo R, Niso-Santano M, Moran JM, Ortiz-Ortiz MA, Bravo-San PedroJM, Soler G, Fuentes JM. 2009. Silencing DJ-1 reveals its contribution in paraquat-induced autophagy. J Neurochem 109: 889-898.
-
(2009)
J Neurochem
, vol.109
, pp. 889-898
-
-
Gonzalez-Polo, R.1
Niso-Santano, M.2
Moran, J.M.3
Ortiz-Ortiz, M.A.4
Bravo-San Pedro, J.M.5
Soler, G.6
Fuentes, J.M.7
-
83
-
-
11844274735
-
Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells
-
Gorman AM, Szegezdi E, Quigney DJ, Samali A. 2005. Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells. Biochem Biophys Res Commun 327: 801-810.
-
(2005)
Biochem Biophys Res Commun
, vol.327
, pp. 801-810
-
-
Gorman, A.M.1
Szegezdi, E.2
Quigney, D.J.3
Samali, A.4
-
84
-
-
58149475992
-
Effects of calpain inhibition on dopaminergic markers and motor function following intrastriatal 6-hydroxydopamine administration in rats
-
Grant RJ, Sellings LH, Crocker SJ, Melloni E, Park DS, Clarke PB. 2009. Effects of calpain inhibition on dopaminergic markers and motor function following intrastriatal 6-hydroxydopamine administration in rats. Neuroscience 158:558-569.
-
(2009)
Neuroscience
, vol.158
, pp. 558-569
-
-
Grant, R.J.1
Sellings, L.H.2
Crocker, S.J.3
Melloni, E.4
Park, D.S.5
Clarke, P.B.6
-
85
-
-
84886695034
-
Means to an end
-
Cold Spring Harbor Laboratory Press, Cold Spring, NY
-
Green DG. 2011. Means to an end. Apoptosis and other cell death mechanisms. Cold Spring Harbor Laboratory Press, Cold Spring, NY.
-
(2011)
Apoptosis and other cell death mechanisms.
-
-
Green, D.G.1
-
86
-
-
0032575752
-
Mitochondria and apoptosis
-
Green DR, Reed JC. 1998. Mitochondria and apoptosis. Science 281:1309-1312.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
87
-
-
0037386532
-
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
-
Greene JC, Whitworth AJ, Kuo I, Andrews LA, Feany MB, Pallanck LJ. 2003. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc Natl Acad Sci 100: 4078-4083.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 4078-4083
-
-
Greene, J.C.1
Whitworth, A.J.2
Kuo, I.3
Andrews, L.A.4
Feany, M.B.5
Pallanck, L.J.6
-
88
-
-
36348989007
-
Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway
-
Guo X, Chen KH, Guo Y, Liao H, Tang J, Xiao RP. 2007. Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway. Circ Res 101: 1113-1122.
-
(2007)
Circ Res
, vol.101
, pp. 1113-1122
-
-
Guo, X.1
Chen, K.H.2
Guo, Y.3
Liao, H.4
Tang, J.5
Xiao, R.P.6
-
89
-
-
79956199220
-
Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures
-
Hakimi M, Selvanantham T, Swinton E, Padmore RF, Tong Y, Kabbach G, Venderova K, Girardin SE, Bulman DE, Scherzer CR, et al. 2011. Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures. J Neural Transm 118:795-808.
-
(2011)
J Neural Transm
, vol.118
, pp. 795-808
-
-
Hakimi, M.1
Selvanantham, T.2
Swinton, E.3
Padmore, R.F.4
Tong, Y.5
Kabbach, G.6
Venderova, K.7
Girardin, S.E.8
Bulman, D.E.9
Scherzer, C.R.10
-
90
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-MigishimaR, Yokoyama M, Mishima K, Saito I, Okano H, et al. 2006. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441: 885-889.
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
Yokoyama, M.7
Mishima, K.8
Saito, I.9
Okano, H.10
-
91
-
-
84975751684
-
Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: Relevance to Parkinson's disease
-
Hartley A, Stone JM, Heron C, Cooper JM, Schapira AH. 1994. Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: Relevance to Parkinson's disease. J Neurochem 63: 1987-1990.
-
(1994)
J Neurochem
, vol.63
, pp. 1987-1990
-
-
Hartley, A.1
Stone, J.M.2
Heron, C.3
Cooper, J.M.4
Schapira, A.H.5
-
92
-
-
12944250987
-
Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease
-
Hartmann A, Hunot S, Michel PP, Muriel MP, Vyas S, Faucheux BA, Mouatt-Prigent A, Turmel H, Srinivasan A, Ruberg M, et al. 2000. Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. Proc Natl Acad Sci 97: 2875-2880.
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 2875-2880
-
-
Hartmann, A.1
Hunot, S.2
Michel, P.P.3
Muriel, M.P.4
Vyas, S.5
Faucheux, B.A.6
Mouatt-Prigent, A.7
Turmel, H.8
Srinivasan, A.9
Ruberg, M.10
-
93
-
-
0035103294
-
Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?
-
Hartmann A, Michel PP, Troadec JD, Mouatt-Prigent A, Faucheux BA, Ruberg M, Agid Y, Hirsch EC. 2001a. Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease? J Neurochem 76: 1785-1793.
-
(2001)
J Neurochem
, vol.76
, pp. 1785-1793
-
-
Hartmann, A.1
Michel, P.P.2
Troadec, J.D.3
Mouatt-Prigent, A.4
Faucheux, B.A.5
Ruberg, M.6
Agid, Y.7
Hirsch, E.C.8
-
94
-
-
0035313071
-
Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis
-
Hartmann A, Troadec JD, Hunot S, Kikly K, Faucheux BA, Mouatt-Prigent A, Ruberg M, Agid Y, Hirsch EC. 2001b. Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis. J Neurosci 21: 2247-2255.
-
(2001)
J Neurosci
, vol.21
, pp. 2247-2255
-
-
Hartmann, A.1
Troadec, J.D.2
Hunot, S.3
Kikly, K.4
Faucheux, B.A.5
Mouatt-Prigent, A.6
Ruberg, M.7
Agid, Y.8
Hirsch, E.C.9
-
95
-
-
0036311251
-
Increased expression and redistribution of the antiapoptotic molecule Bcl-xL in Parkinson's disease
-
Hartmann A, Mouatt-Prigent A, Vila M, Abbas N, Perier C, Faucheux BA, VyasS, Hirsch EC. 2002. Increased expression and redistribution of the antiapoptotic molecule Bcl-xL in Parkinson's disease. Neurobiol Dis 10: 28-32.
-
(2002)
Neurobiol Dis
, vol.10
, pp. 28-32
-
-
Hartmann, A.1
Mouatt-Prigent, A.2
Vila, M.3
Abbas, N.4
Perier, C.5
Faucheux, B.A.6
Vyas, S.7
Hirsch, E.C.8
-
96
-
-
27844595293
-
Caspase and calpain function in cell death: Bridging the gap between apoptosis and necrosis
-
Harwood SM, Yaqoob MM, Allen DA. 2005. Caspase and calpain function in cell death: Bridging the gap between apoptosis and necrosis. Ann Clin Biochem 42: 415-431.
-
(2005)
Ann Clin Biochem
, vol.42
, pp. 415-431
-
-
Harwood, S.M.1
Yaqoob, M.M.2
Allen, D.A.3
-
97
-
-
0029670980
-
Increase in bax expression in substantia nigra following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment of mice
-
Hassouna I, Wickert H, Zimmermann M, Gillardon F. 1996. Increase in bax expression in substantia nigra following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment of mice. Neurosci Lett 204: 85-88.
-
(1996)
Neurosci Lett
, vol.204
, pp. 85-88
-
-
Hassouna, I.1
Wickert, H.2
Zimmermann, M.3
Gillardon, F.4
-
98
-
-
32344444326
-
Down-regulation of α-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson's disease rat model
-
Hayashita-Kinoh H, Yamada M, Yokota T, Mizuno Y, Mochizuki H. 2006. Down-regulation of α-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson's disease rat model. Biochem Biophys Res Commun 341: 1088-1095.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 1088-1095
-
-
Hayashita-Kinoh, H.1
Yamada, M.2
Yokota, T.3
Mizuno, Y.4
Mochizuki, H.5
-
99
-
-
10744223673
-
Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
-
Hayley S, Crocker SJ, Smith PD, Shree T, Jackson-Lewis V, Przedborski S, Mount M, Slack R, Anisman H, Park DS. 2004. Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J Neurosci 24: 2045-2053.
-
(2004)
J Neurosci
, vol.24
, pp. 2045-2053
-
-
Hayley, S.1
Crocker, S.J.2
Smith, P.D.3
Shree, T.4
Jackson-Lewis, V.5
Przedborski, S.6
Mount, M.7
Slack, R.8
Anisman, H.9
Park, D.S.10
-
100
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi J, Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ, Yuan J. 2008. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 135: 1311-1323.
-
(2008)
Cell
, vol.135
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
Yuan, J.7
-
101
-
-
59649089328
-
The Parkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration
-
Ho CC, Rideout HJ, Ribe E, Troy CM, Dauer WT. 2009. The Parkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration. J Neurosci 29: 1011-1016.
-
(2009)
J Neurosci
, vol.29
, pp. 1011-1016
-
-
Ho, C.C.1
Rideout, H.J.2
Ribe, E.3
Troy, C.M.4
Dauer, W.T.5
-
102
-
-
0036479115
-
Transcriptional repression of the anti-apoptotic survivin gene by wild type 53
-
Hoffman WH, Biade S, Zilfou JT, Chen J, Murphy M. 2002. Transcriptional repression of the anti-apoptotic survivin gene by wild type 53. J Biol Chem 277:3247-3257.
-
(2002)
J Biol Chem
, vol.277
, pp. 3247-3257
-
-
Hoffman, W.H.1
Biade, S.2
Zilfou, J.T.3
Chen, J.4
Murphy, M.5
-
103
-
-
17644407706
-
Microarray expression profiling identifies early signaling transcripts associated with 6-OHDA-induced dopaminergic cell death
-
Holtz WA, Turetzky JM, O'Malley KL. 2005. Microarray expression profiling identifies early signaling transcripts associated with 6-OHDA-induced dopaminergic cell death. Antioxid Redox Signal 7: 639-648.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 639-648
-
-
Holtz, W.A.1
Turetzky, J.M.2
O'Malley, K.L.3
-
105
-
-
77953121792
-
The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death
-
Huang E, Qu D, Zhang Y, Venderova K, Haque ME, Rousseaux MW, Slack RS, Woulfe JM, Park DS. 2010. The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death. Nat Cell Biol 12: 563-571.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 563-571
-
-
Huang, E.1
Qu, D.2
Zhang, Y.3
Venderova, K.4
Haque, M.E.5
Rousseaux, M.W.6
Slack, R.S.7
Woulfe, J.M.8
Park, D.S.9
-
106
-
-
77955058151
-
Parkin suppresses c-Jun N-terminal kinase-induced cell death via transcriptional regulation in Drosophila
-
Hwang S, Kim D, Choi G, An SW, Hong YK, Suh YS, Lee MJ, Cho KS. 2010. Parkin suppresses c-Jun N-terminal kinase-induced cell death via transcriptional regulation in Drosophila. Mol Cells 29: 575-580.
-
(2010)
Mol Cells
, vol.29
, pp. 575-580
-
-
Hwang, S.1
Kim, D.2
Choi, G.3
An, S.W.4
Hong, Y.K.5
Suh, Y.S.6
Lee, M.J.7
Cho, K.S.8
-
107
-
-
34447294546
-
Apoptotic mechanisms in mutant LRRK2-mediated cell death
-
Iaccarino C, Crosio C, Vitale C, Sanna G, Carri MT, Barone P. 2007. Apoptotic mechanisms in mutant LRRK2-mediated cell death. Human Mol Genet 16:1319-1326.
-
(2007)
Human Mol Genet
, vol.16
, pp. 1319-1326
-
-
Iaccarino, C.1
Crosio, C.2
Vitale, C.3
Sanna, G.4
Carri, M.T.5
Barone, P.6
-
108
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K, Gotoh Y. 1997. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275: 90-94.
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
Ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
Takagi, M.7
Matsumoto, K.8
Miyazono, K.9
Gotoh, Y.10
-
109
-
-
0034680913
-
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
-
Imai Y, Soda M, Takahashi R. 2000. Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J Biol Chem 275: 35661-35664.
-
(2000)
J Biol Chem
, vol.275
, pp. 35661-35664
-
-
Imai, Y.1
Soda, M.2
Takahashi, R.3
-
110
-
-
77956522541
-
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
-
Irrcher I, Aleyasin H, Seifert EL, Hewitt SJ, Chhabra S, Phillips M, Lutz AK, Rousseaux MW, Bevilacqua L, Jahani-Asl A, et al. 2010. Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Human Mol Genet 19: 3734-3746.
-
(2010)
Human Mol Genet
, vol.19
, pp. 3734-3746
-
-
Irrcher, I.1
Aleyasin, H.2
Seifert, E.L.3
Hewitt, S.J.4
Chhabra, S.5
Phillips, M.6
Lutz, A.K.7
Rousseaux, M.W.8
Bevilacqua, L.9
Jahani-Asl, A.10
-
111
-
-
0028784523
-
Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
Jackson-Lewis V, Jakowec M, Burke RE, Przedborski S. 1995. Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neurodegeneration 4: 257-269.
-
(1995)
Neurodegeneration
, vol.4
, pp. 257-269
-
-
Jackson-Lewis, V.1
Jakowec, M.2
Burke, R.E.3
Przedborski, S.4
-
112
-
-
10744228800
-
Puma is an essential mediator of p53-dependent and-independent apoptotic pathways
-
Jeffers JR, Parganas E, Lee Y, Yang C, Wang J, Brennan J, MacLean KH, Han J, Chittenden T, Ihle JN, et al. 2003. Puma is an essential mediator of p53-dependent and-independent apoptotic pathways. Cancer cell 4: 321-328.
-
(2003)
Cancer cell
, vol.4
, pp. 321-328
-
-
Jeffers, J.R.1
Parganas, E.2
Lee, Y.3
Yang, C.4
Wang, J.5
Brennan, J.6
McLean, K.H.7
Han, J.8
Chittenden, T.9
Ihle, J.N.10
-
113
-
-
0033955608
-
Cell death mechanisms in Parkinson's disease
-
Jellinger KA. 2000. Cell death mechanisms in Parkinson's disease. J Neural Transm 107: 1-29.
-
(2000)
J Neural Transm
, vol.107
, pp. 1-29
-
-
Jellinger, K.A.1
-
114
-
-
0029018424
-
6-Hydroxydopamine lesion of the rat substantia nigra: Time course and morphology of cell death
-
Jeon BS, Jackson-Lewis V, Burke RE. 1995. 6-Hydroxydopamine lesion of the rat substantia nigra: Time course and morphology of cell death. Neurodegeneration 4: 131-137.
-
(1995)
Neurodegeneration
, vol.4
, pp. 131-137
-
-
Jeon, B.S.1
Jackson-Lewis, V.2
Burke, R.E.3
-
115
-
-
4444327827
-
Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis
-
Jiang H, Ren Y, Zhao J, Feng J. 2004. Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis. Human Mol Genet 13: 1745-1754.
-
(2004)
Human Mol Genet
, vol.13
, pp. 1745-1754
-
-
Jiang, H.1
Ren, Y.2
Zhao, J.3
Feng, J.4
-
116
-
-
22144465488
-
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
-
Junn E, Taniguchi H, Jeong BS, Zhao X, Ichijo H, Mouradian MM. 2005. Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death. Proc Natl Acad Sci 102: 9691-9696.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 9691-9696
-
-
Junn, E.1
Taniguchi, H.2
Jeong, B.S.3
Zhao, X.4
Ichijo, H.5
Mouradian, M.M.6
-
117
-
-
77956521263
-
Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila
-
Kanao T, Venderova K, Park DS, Unterman T, Lu B, Imai Y. 2010. Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila. Human Mol Genet 19:3747-3758.
-
(2010)
Human Mol Genet
, vol.19
, pp. 3747-3758
-
-
Kanao, T.1
Venderova, K.2
Park, D.S.3
Unterman, T.4
Lu, B.5
Imai, Y.6
-
118
-
-
0037164813
-
Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis
-
Karbowski M, Lee YJ, Gaume B, Jeong SY, Frank S, Nechushtan A, Santel A, Fuller M, Smith CL, Youle RJ. 2002. Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis. J Cell Biol 159:931-938.
-
(2002)
J Cell Biol
, vol.159
, pp. 931-938
-
-
Karbowski, M.1
Lee, Y.J.2
Gaume, B.3
Jeong, S.Y.4
Frank, S.5
Nechushtan, A.6
Santel, A.7
Fuller, M.8
Smith, C.L.9
Youle, R.J.10
-
119
-
-
33749846225
-
Role of Bax and Bak in mitochondrial morphogenesis
-
Karbowski M, Norris KL, Cleland MM, Jeong SY, Youle RJ. 2006. Role of Bax and Bak in mitochondrial morphogenesis. Nature 443: 658-662.
-
(2006)
Nature
, vol.443
, pp. 658-662
-
-
Karbowski, M.1
Norris, K.L.2
Cleland, M.M.3
Jeong, S.Y.4
Youle, R.J.5
-
120
-
-
58149393845
-
Selective activation of p38 mitogen-activated protein kinase in dopaminergic neurons of substantia nigra leads to nuclear translocation of p53 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice
-
Karunakaran S, Saeed U, Mishra M, Valli RK, Joshi SD, Meka DP, Seth P, Ravindranath V. 2008. Selective activation of p38 mitogen-activated protein kinase in dopaminergic neurons of substantia nigra leads to nuclear translocation of p53 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice. J Neurosci 28: 12500-12509.
-
(2008)
J Neurosci
, vol.28
, pp. 12500-12509
-
-
Karunakaran, S.1
Saeed, U.2
Mishra, M.3
Valli, R.K.4
Joshi, S.D.5
Meka, D.P.6
Seth, P.7
Ravindranath, V.8
-
121
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JF, Wyllie AH, Currie AR. 1972. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26: 239-257.
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
122
-
-
20144389422
-
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
-
Kim RH, Smith PD, Aleyasin H, Hayley S, Mount MP, Pownall S, Wakeham A, You-Ten AJ, Kalia SK, Horne P, et al. 2005. Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. Proc Natl Acad Sci 102: 5215-5220.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 5215-5220
-
-
Kim, R.H.1
Smith, P.D.2
Aleyasin, H.3
Hayley, S.4
Mount, M.P.5
Pownall, S.6
Wakeham, A.7
You-Ten, A.J.8
Kalia, S.K.9
Horne, P.10
-
123
-
-
0032408087
-
Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic death in human neuroblastoma SH-SY5Y cells
-
Kitamura Y, Kosaka T, Kakimura JI, Matsuoka Y, Kohno Y, Nomura Y, TaniguchiT. 1998. Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic death in human neuroblastoma SH-SY5Y cells. Mol Pharmacol 54: 1046-1054.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 1046-1054
-
-
Kitamura, Y.1
Kosaka, T.2
Kakimura, J.I.3
Matsuoka, Y.4
Kohno, Y.5
Nomura, Y.6
Taniguchi, T.7
-
124
-
-
77951925834
-
Enhanced vulnerability of PARK6 patient skin fibroblasts to apoptosis induced by proteasomal stress
-
Klinkenberg M, Thurow N, Gispert S, Ricciardi F, Eich F, Prehn JH, Auburger G, Kogel D. 2010. Enhanced vulnerability of PARK6 patient skin fibroblasts to apoptosis induced by proteasomal stress. Neuroscience 166: 422-434.
-
(2010)
Neuroscience
, vol.166
, pp. 422-434
-
-
Klinkenberg, M.1
Thurow, N.2
Gispert, S.3
Ricciardi, F.4
Eich, F.5
Prehn, J.H.6
Auburger, G.7
Kogel, D.8
-
125
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, Tanida I, Ueno T, Koike M, Uchiyama Y, Kominami E, et al. 2006. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 441: 880-884.
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
Tanida, I.6
Ueno, T.7
Koike, M.8
Uchiyama, Y.9
Kominami, E.10
-
126
-
-
0036282745
-
Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
-
Konishi Y, Lehtinen M, Donovan N, Bonni A. 2002. Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol Cell 9: 1005-1016.
-
(2002)
Mol Cell
, vol.9
, pp. 1005-1016
-
-
Konishi, Y.1
Lehtinen, M.2
Donovan, N.3
Bonni, A.4
-
127
-
-
1842297607
-
On the question of apoptosis in the parkinsonian substantia nigra
-
Kosel S, Egensperger R, von Eitzen U, Mehraein P, Graeber MB. 1997. On the question of apoptosis in the parkinsonian substantia nigra. Acta Neuropathol 93: 105-108.
-
(1997)
Acta Neuropathol
, vol.93
, pp. 105-108
-
-
Kosel, S.1
Egensperger, R.2
von Eitzen, U.3
Mehraein, P.4
Graeber, M.B.5
-
128
-
-
27844495164
-
Molecular basis of programmed cell death involved in neurodegeneration
-
Krantic S, Mechawar N, Reix S, Quirion R. 2005. Molecular basis of programmed cell death involved in neurodegeneration. Trends Neurosci 28:670-676.
-
(2005)
Trends Neurosci
, vol.28
, pp. 670-676
-
-
Krantic, S.1
Mechawar, N.2
Reix, S.3
Quirion, R.4
-
129
-
-
77949623516
-
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1
-
Krebiehl G, Ruckerbauer S, Burbulla LF, Kieper N, Maurer B, Waak J, Wolburg H, Gizatullina Z, Gellerich FN, Woitalla D, et al. 2010. Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1. PloS ONE 5: e9367.
-
(2010)
PloS ONE
, vol.5
-
-
Krebiehl, G.1
Ruckerbauer, S.2
Burbulla, L.F.3
Kieper, N.4
Maurer, B.5
Waak, J.6
Wolburg, H.7
Gizatullina, Z.8
Gellerich, F.N.9
Woitalla, D.10
-
130
-
-
84856764253
-
Regulation of CD95/Fas signaling at the DISC
-
Lavrik IN, Krammer PH. 2012. Regulation of CD95/Fas signaling at the DISC. Cell Death Differ 19: 36-41.
-
(2012)
Cell Death Differ
, vol.19
, pp. 36-41
-
-
Lavrik, I.N.1
Krammer, P.H.2
-
131
-
-
84855568952
-
Apoptosis Signal-Regulating Kinase 1 Mediates MPTP Toxicity and Regulates Glial Activation
-
Lee KW, Zhao X, Im JY, Grosso H, Jang WH, Chan TW, Sonsalla PK, German DC, Ichijo H, Junn E, et al. 2012. Apoptosis Signal-Regulating Kinase 1 Mediates MPTP Toxicity and Regulates Glial Activation. PloS ONE 7: e29935.
-
(2012)
PloS ONE
, vol.7
-
-
Lee, K.W.1
Zhao, X.2
Im, J.Y.3
Grosso, H.4
Jang, W.H.5
Chan, T.W.6
Sonsalla, P.K.7
German, D.C.8
Ichijo, H.9
Junn, E.10
-
132
-
-
0037418238
-
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
-
Lei K, Davis RJ. 2003. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci 100: 2432-2437.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 2432-2437
-
-
Lei, K.1
Davis, R.J.2
-
133
-
-
0036775488
-
Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy
-
Lemasters JJ, Qian T, He L, Kim JS, Elmore SP, Cascio WE, Brenner DA. 2002. Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy. Antioxid Redox Signal 4: 769-781.
-
(2002)
Antioxid Redox Signal
, vol.4
, pp. 769-781
-
-
Lemasters, J.J.1
Qian, T.2
He, L.3
Kim, J.S.4
Elmore, S.P.5
Cascio, W.E.6
Brenner, D.A.7
-
134
-
-
20744445814
-
Antiapoptotic property of human α-synuclein in neuronal cell lines is associated with the inhibition of caspase-3 but not caspase-9 activity
-
Li W, Lee MK. 2005. Antiapoptotic property of human α-synuclein in neuronal cell lines is associated with the inhibition of caspase-3 but not caspase-9 activity. J Neurochem 93: 1542-1550.
-
(2005)
J Neurochem
, vol.93
, pp. 1542-1550
-
-
Li, W.1
Lee, M.K.2
-
135
-
-
10944269186
-
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
-
Li Z, Okamoto K, Hayashi Y, Sheng M. 2004. The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell 119: 873-887.
-
(2004)
Cell
, vol.119
, pp. 873-887
-
-
Li, Z.1
Okamoto, K.2
Hayashi, Y.3
Sheng, M.4
-
136
-
-
33947707798
-
NF-kappaB contributes to 6-hydroxydopamine-induced apoptosis of nigral dopaminergic neurons through 53
-
Liang ZQ, Li YL, Zhao XL, Han R, Wang XX, Wang Y, Chase TN, Bennett MC, QinZH. 2007. NF-kappaB contributes to 6-hydroxydopamine-induced apoptosis of nigral dopaminergic neurons through 53. Brain Res 1145: 190-203.
-
(2007)
Brain Res
, vol.1145
, pp. 190-203
-
-
Liang, Z.Q.1
Li, Y.L.2
Zhao, X.L.3
Han, R.4
Wang, X.X.5
Wang, Y.6
Chase, T.N.7
Bennett, M.C.8
Qin, Z.H.9
-
137
-
-
45249112594
-
Characterization of PINK1 processing, stability, and subcellular localization
-
Lin W, Kang UJ. 2008. Characterization of PINK1 processing, stability, and subcellular localization. J Neurochem 106: 464-474.
-
(2008)
J Neurochem
, vol.106
, pp. 464-474
-
-
Lin, W.1
Kang, U.J.2
-
138
-
-
23444446684
-
BimEL up-regulation potentiates AIF translocation and cell death in response to MPTP
-
Liou AK, Zhou Z, Pei W, Lim TM, Yin XM, Chen J. 2005. BimEL up-regulation potentiates AIF translocation and cell death in response to MPTP. FASEB J 19:1350-1352.
-
(2005)
FASEB J
, vol.19
, pp. 1350-1352
-
-
Liou, A.K.1
Zhou, Z.2
Pei, W.3
Lim, T.M.4
Yin, X.M.5
Chen, J.6
-
139
-
-
79955109480
-
Cdk 5: Multitasking between physiological and pathological conditions
-
Lopes JP, Agostinho P. 2011. Cdk 5: Multitasking between physiological and pathological conditions. Prog Neurobiol 94: 49-63.
-
(2011)
Prog Neurobiol
, vol.94
, pp. 49-63
-
-
Lopes, J.P.1
Agostinho, P.2
-
140
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, Thompson CB. 2005. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120: 237-248.
-
(2005)
Cell
, vol.120
, pp. 237-248
-
-
Lum, J.J.1
Bauer, D.E.2
Kong, M.3
Harris, M.H.4
Li, C.5
Lindsten, T.6
Thompson, C.B.7
-
142
-
-
21144449349
-
Common anti-apoptotic roles of parkin and α-synuclein in human dopaminergic cells
-
Machida Y, Chiba T, Takayanagi A, Tanaka Y, Asanuma M, Ogawa N, KoyamaA, Iwatsubo T, Ito S, Jansen PH, et al. 2005. Common anti-apoptotic roles of parkin and α-synuclein in human dopaminergic cells. Biochem Biophys Res Commun 332: 233-240.
-
(2005)
Biochem Biophys Res Commun
, vol.332
, pp. 233-240
-
-
McHida, Y.1
Chiba, T.2
Takayanagi, A.3
Tanaka, Y.4
Asanuma, M.5
Ogawa, N.6
Koyama, A.7
Iwatsubo, T.8
Ito, S.9
Jansen, P.H.10
-
143
-
-
33751256567
-
The familial Parkinsonism gene LRRK2 regulates neurite process morphology
-
MacLeod D, Dowman J, Hammond R, Leete T, Inoue K, Abeliovich A. 2006. The familial Parkinsonism gene LRRK2 regulates neurite process morphology. Neuron 52: 587-593.
-
(2006)
Neuron
, vol.52
, pp. 587-593
-
-
McLeod, D.1
Dowman, J.2
Hammond, R.3
Leete, T.4
Inoue, K.5
Abeliovich, A.6
-
144
-
-
34248998801
-
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
-
Maiuri MC, Le Toumelin G, Criollo A, Rain JC, Gautier F, Juin P, Tasdemir E, Pierron G, Troulinaki K, Tavernarakis N, et al. 2007a. Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J 26:2527-2539.
-
(2007)
EMBO J
, vol.26
, pp. 2527-2539
-
-
Maiuri, M.C.1
Le Toumelin, G.2
Criollo, A.3
Rain, J.C.4
Gautier, F.5
Juin, P.6
Tasdemir, E.7
Pierron, G.8
Troulinaki, K.9
Tavernarakis, N.10
-
146
-
-
0033545925
-
Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism
-
Mandir AS, Przedborski S, Jackson-Lewis V, Wang ZQ, Simbulan-RosenthalCM, Smulson ME, Hoffman BE, Guastella DB, Dawson VL, Dawson TM. 1999. Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism. Proc Natl Acad Sci 96:5774-5779.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 5774-5779
-
-
Mandir, A.S.1
Przedborski, S.2
Jackson-Lewis, V.3
Wang, Z.Q.4
Simbulan-Rosenthal, C.M.5
Smulson, M.E.6
Hoffman, B.E.7
Guastella, D.B.8
Dawson, V.L.9
Dawson, T.M.10
-
147
-
-
0036788183
-
A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism
-
Mandir AS, Simbulan-Rosenthal CM, Poitras MF, Lumpkin JR, Dawson VL, Smulson ME, Dawson TM. 2002. A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism. J Neurochem 83: 186-192.
-
(2002)
J Neurochem
, vol.83
, pp. 186-192
-
-
Mandir, A.S.1
Simbulan-Rosenthal, C.M.2
Poitras, M.F.3
Lumpkin, J.R.4
Dawson, V.L.5
Smulson, M.E.6
Dawson, T.M.7
-
148
-
-
0031558778
-
Upregulation of the anti-apoptotic protein Bcl-2 may be an early event in neurodegeneration: Studies on Parkinson's and incidental Lewy body disease
-
Marshall KA, Daniel SE, Cairns N, Jenner P, Halliwell B. 1997. Upregulation of the anti-apoptotic protein Bcl-2 may be an early event in neurodegeneration: Studies on Parkinson's and incidental Lewy body disease. Biochem Biophys Res Commun 240: 84-87.
-
(1997)
Biochem Biophys Res Commun
, vol.240
, pp. 84-87
-
-
Marshall, K.A.1
Daniel, S.E.2
Cairns, N.3
Jenner, P.4
Halliwell, B.5
-
149
-
-
30644471051
-
Parkinson's disease α-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
-
Martin LJ, Pan Y, Price AC, Sterling W, Copeland NG, Jenkins NA, Price DL, LeeMK. 2006. Parkinson's disease α-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. J Neurosci 26: 41-50.
-
(2006)
J Neurosci
, vol.26
, pp. 41-50
-
-
Martin, L.J.1
Pan, Y.2
Price, A.C.3
Sterling, W.4
Copeland, N.G.5
Jenkins, N.A.6
Price, D.L.7
Lee, M.K.8
-
150
-
-
13944279784
-
Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: An ES-derived cell model of primary Parkinsonism
-
Martinat C, Shendelman S, Jonason A, Leete T, Beal MF, Yang L, Floss T, Abeliovich A. 2004. Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: An ES-derived cell model of primary Parkinsonism. PLoS Biol 2: e327.
-
(2004)
PLoS Biol
, vol.2
-
-
Martinat, C.1
Shendelman, S.2
Jonason, A.3
Leete, T.4
Beal, M.F.5
Yang, L.6
Floss, T.7
Abeliovich, A.8
-
151
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
-
Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier CA, Sou YS, Saiki S, Kawajiri S, Sato F, et al. 2010. PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J Cell Biol 189: 211-221.
-
(2010)
J Cell Biol
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
Saisho, K.5
Gautier, C.A.6
Sou, Y.S.7
Saiki, S.8
Kawajiri, S.9
Sato, F.10
-
152
-
-
79955701611
-
DJ-1 regulation of mitochondrial function and autophagy through oxidative stress
-
McCoy MK, Cookson MR. 2011. DJ-1 regulation of mitochondrial function and autophagy through oxidative stress. Autophagy 7: 531-532.
-
(2011)
Autophagy
, vol.7
, pp. 531-532
-
-
McCoy, M.K.1
Cookson, M.R.2
-
153
-
-
65249108225
-
FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation
-
Mei Y, Zhang Y, Yamamoto K, Xie W, Mak TW, You H. 2009. FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation. Proc Natl Acad Sci 106: 5153-5158.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 5153-5158
-
-
Mei, Y.1
Zhang, Y.2
Yamamoto, K.3
Xie, W.4
Mak, T.W.5
You, H.6
-
154
-
-
33947356299
-
Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis
-
Meuer K, Suppanz IE, Lingor P, Planchamp V, Goricke B, Fichtner L, Braus GH, Dietz GP, Jakobs S, Bahr M, et al. 2007. Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis. Cell Death Differ 14: 651-661.
-
(2007)
Cell Death Differ
, vol.14
, pp. 651-661
-
-
Meuer, K.1
Suppanz, I.E.2
Lingor, P.3
Planchamp, V.4
Goricke, B.5
Fichtner, L.6
Braus, G.H.7
Dietz, G.P.8
Jakobs, S.9
Bahr, M.10
-
155
-
-
0029942337
-
Histochemical detection of apoptosis in Parkinson's disease
-
Mochizuki H, Goto K, Mori H, Mizuno Y. 1996. Histochemical detection of apoptosis in Parkinson's disease. J Neurolog Sci 137: 120-123.
-
(1996)
J Neurolog Sci
, vol.137
, pp. 120-123
-
-
Mochizuki, H.1
Goto, K.2
Mori, H.3
Mizuno, Y.4
-
156
-
-
0030572714
-
Bcl-2 protein is increased in the brain from parkinsonian patients
-
Mogi M, Harada M, Kondo T, Mizuno Y, Narabayashi H, Riederer P, Nagatsu T.1996. bcl-2 protein is increased in the brain from parkinsonian patients. Neurosci Lett 215: 137-139.
-
(1996)
Neurosci Lett
, vol.215
, pp. 137-139
-
-
Mogi, M.1
Harada, M.2
Kondo, T.3
Mizuno, Y.4
Narabayashi, H.5
Riederer, P.6
Nagatsu, T.7
-
157
-
-
0034023082
-
Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from parkinsonian brain
-
Mogi M, Togari A, Kondo T, Mizuno Y, Komure O, Kuno S, Ichinose H, NagatsuT. 2000. Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from parkinsonian brain. J Neural Transm 107:335-341.
-
(2000)
J Neural Transm
, vol.107
, pp. 335-341
-
-
Mogi, M.1
Togari, A.2
Kondo, T.3
Mizuno, Y.4
Komure, O.5
Kuno, S.6
Ichinose, H.7
Nagatsu, T.8
-
158
-
-
0029882525
-
Increased M-calpain expression in the mesencephalon of patients with Parkinson's disease but not in other neurodegenerative disorders involving the mesencephalon: A role in nerve cell death?
-
Mouatt-Prigent A, Karlsson JO, Agid Y, Hirsch EC. 1996. Increased M-calpain expression in the mesencephalon of patients with Parkinson's disease but not in other neurodegenerative disorders involving the mesencephalon: A role in nerve cell death? Neuroscience 73: 979-987.
-
(1996)
Neuroscience
, vol.73
, pp. 979-987
-
-
Mouatt-Prigent, A.1
Karlsson, J.O.2
Agid, Y.3
Hirsch, E.C.4
-
159
-
-
33745010726
-
Activation of p53 signaling initiates apoptotic death in a cellular model of Parkinson's disease
-
Nair VD. 2006. Activation of p53 signaling initiates apoptotic death in a cellular model of Parkinson's disease. Apoptosis 11: 955-966.
-
(2006)
Apoptosis
, vol.11
, pp. 955-966
-
-
Nair, V.D.1
-
160
-
-
0034881326
-
Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA
-
Nakada K, Inoue K, Ono T, Isobe K, Ogura A, Goto YI, Nonaka I, Hayashi JI.2001. Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA. Nat Med 7: 934-940.
-
(2001)
Nat Med
, vol.7
, pp. 934-940
-
-
Nakada, K.1
Inoue, K.2
Ono, T.3
Isobe, K.4
Ogura, A.5
Goto, Y.I.6
Nonaka, I.7
Hayashi, J.I.8
-
161
-
-
0030749732
-
P35nck5a and cyclin-dependent kinase 5 colocalize in Lewy bodies of brains with Parkinson's disease
-
Nakamura S, Kawamoto Y, Nakano S, Akiguchi I, Kimura J. 1997. p35nck5a and cyclin-dependent kinase 5 colocalize in Lewy bodies of brains with Parkinson's disease. Acta Neuropathol 94: 153-157.
-
(1997)
Acta Neuropathol
, vol.94
, pp. 153-157
-
-
Nakamura, S.1
Kawamoto, Y.2
Nakano, S.3
Akiguchi, I.4
Kimura, J.5
-
162
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D, Tanaka A, Suen DF, Youle RJ. 2008. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 183:795-803.
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
163
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra DP, Jin SM, Tanaka A, Suen DF, Gautier CA, Shen J, Cookson MR, Youle RJ. 2010. PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol 8: e1000298.
-
(2010)
PLoS Biol
, vol.8
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
164
-
-
0034994657
-
Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA-induced degeneration
-
Natsume A, Mata M, Goss J, Huang S, Wolfe D, Oligino T, Glorioso J, Fink DJ.2001. Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA-induced degeneration. Exp Neurol 169: 231-238.
-
(2001)
Exp Neurol
, vol.169
, pp. 231-238
-
-
Natsume, A.1
Mata, M.2
Goss, J.3
Huang, S.4
Wolfe, D.5
Oligino, T.6
Glorioso, J.7
Fink, D.J.8
-
165
-
-
0023093745
-
MPTP, MPP+ and mitochondrial function
-
Nicklas WJ, Youngster SK, Kindt MV, Heikkila RE. 1987. MPTP, MPP+ and mitochondrial function. Life Sci 40: 721-729.
-
(1987)
Life Sci
, vol.40
, pp. 721-729
-
-
Nicklas, W.J.1
Youngster, S.K.2
Kindt, M.V.3
Heikkila, R.E.4
-
166
-
-
0034903725
-
Glycine blocks opening of a death channel in cultured hepatic sinusoidal endothelial cells during chemical hypoxia
-
Nishimura Y, Lemasters JJ. 2001. Glycine blocks opening of a death channel in cultured hepatic sinusoidal endothelial cells during chemical hypoxia. Cell Death Differ 8: 850-858.
-
(2001)
Cell Death Differ
, vol.8
, pp. 850-858
-
-
Nishimura, Y.1
Lemasters, J.J.2
-
167
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A, Ichijo H. 2002. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 16: 1345-1355.
-
(2002)
Genes Dev
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Inoue, K.6
Hori, S.7
Kakizuka, A.8
Ichijo, H.9
-
168
-
-
78650553597
-
ASK1 overexpression accelerates paraquat-induced autophagy via endoplasmic reticulum stress
-
Niso-Santano M, Bravo-San Pedro JM, Gomez-Sanchez R, Climent V, Soler G, Fuentes JM, Gonzalez-Polo RA. 2011. ASK1 overexpression accelerates paraquat-induced autophagy via endoplasmic reticulum stress. Toxicol Sci 119: 156-168.
-
(2011)
Toxicol Sci
, vol.119
, pp. 156-168
-
-
Niso-Santano, M.1
Bravo-San Pedro, J.M.2
Gomez-Sanchez, R.3
Climent, V.4
Soler, G.5
Fuentes, J.M.6
Gonzalez-Polo, R.A.7
-
169
-
-
80054888589
-
It cuts both ways: Reconciling the dual roles of caspase 8 in cell death and survival
-
Oberst A, Green DR. 2011. It cuts both ways: Reconciling the dual roles of caspase 8 in cell death and survival. Nat Rev Mol Cell Biol 12: 757-763.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 757-763
-
-
Oberst, A.1
Green, D.R.2
-
170
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T, Tanaka N. 2000. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288: 1053-1058.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
171
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
O'Donnell MA, Perez-Jimenez E, Oberst A, Ng A, Massoumi R, Xavier R, GreenDR, Ting AT. 2011. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 13: 1437-1442.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1437-1442
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
Ng, A.4
Massoumi, R.5
Xavier, R.6
Green, D.R.7
Ting, A.T.8
-
172
-
-
0032510758
-
Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
-
Offen D, Beart PM, Cheung NS, Pascoe CJ, Hochman A, Gorodin S, Melamed E, Bernard R, Bernard O. 1998. Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Proc Natl Acad Sci 95: 5789-5794.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 5789-5794
-
-
Offen, D.1
Beart, P.M.2
Cheung, N.S.3
Pascoe, C.J.4
Hochman, A.5
Gorodin, S.6
Melamed, E.7
Bernard, R.8
Bernard, O.9
-
173
-
-
0036233590
-
Generation and characterization of Smac/DIABLO-deficient mice
-
Okada H, Suh WK, Jin J, Woo M, Du C, Elia A, Duncan GS, Wakeham A, Itie A, Lowe SW, et al. 2002. Generation and characterization of Smac/DIABLO-deficient mice. Mol Cell Biol 22: 3509-3517.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3509-3517
-
-
Okada, H.1
Suh, W.K.2
Jin, J.3
Woo, M.4
Du, C.5
Elia, A.6
Duncan, G.S.7
Wakeham, A.8
Itie, A.9
Lowe, S.W.10
-
174
-
-
0034938453
-
Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria
-
Ono T, Isobe K, Nakada K, Hayashi JI. 2001. Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria. Nat Gen 28: 272-275.
-
(2001)
Nat Gen
, vol.28
, pp. 272-275
-
-
Ono, T.1
Isobe, K.2
Nakada, K.3
Hayashi, J.I.4
-
175
-
-
0035399637
-
Programmed cell death of developing mammalian neurons after genetic deletion of caspases
-
Oppenheim RW, Flavell RA, Vinsant S, Prevette D, Kuan CY, Rakic P. 2001. Programmed cell death of developing mammalian neurons after genetic deletion of caspases. J Neurosci 21: 4752-4760.
-
(2001)
J Neurosci
, vol.21
, pp. 4752-4760
-
-
Oppenheim, R.W.1
Flavell, R.A.2
Vinsant, S.3
Prevette, D.4
Kuan, C.Y.5
Rakic, P.6
-
176
-
-
34247549725
-
Pharmacological inhibition of PARP-1 reduces α-synuclein-and MPP+-induced cytotoxicity in Parkinson's disease in vitro models
-
Outeiro TF, Grammatopoulos TN, Altmann S, Amore A, Standaert DG, HymanBT, Kazantsev AG. 2007. Pharmacological inhibition of PARP-1 reduces α-synuclein-and MPP+-induced cytotoxicity in Parkinson's disease in vitro models. Biochem Biophys Res Commun 357: 596-602.
-
(2007)
Biochem Biophys Res Commun
, vol.357
, pp. 596-602
-
-
Outeiro, T.F.1
Grammatopoulos, T.N.2
Altmann, S.3
Amore, A.4
Standaert, D.G.5
Hyman, B.T.6
Kazantsev, A.G.7
-
177
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
Pandey UB, Nie Z, Batlevi Y, McCray BA, Ritson GP, Nedelsky NB, Schwartz SL, DiProspero NA, Knight MA, Schuldiner O, et al. 2007. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 447: 859-863.
-
(2007)
Nature
, vol.447
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
McCray, B.A.4
Ritson, G.P.5
Nedelsky, N.B.6
Schwartz, S.L.7
DiProspero, N.A.8
Knight, M.A.9
Schuldiner, O.10
-
178
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park J, Lee SB, Lee S, Kim Y, Song S, Kim S, Bae E, Kim J, Shong M, Kim JM, et al.2006. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441: 1157-1161.
-
(2006)
Nature
, vol.441
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
Bae, E.7
Kim, J.8
Shong, M.9
Kim, J.M.10
-
179
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N, Packer M, Schneider MD, Levine B. 2005. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122: 927-939.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Liang, X.H.5
Mizushima, N.6
Packer, M.7
Schneider, M.D.8
Levine, B.9
-
180
-
-
30044442094
-
Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage
-
Perier C, Tieu K, Guegan C, Caspersen C, Jackson-Lewis V, Carelli V, Martinuzzi A, Hirano M, Przedborski S, Vila M. 2005. Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage. Proc Natl Acad Sci 102: 19126-19131.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 19126-19131
-
-
Perier, C.1
Tieu, K.2
Guegan, C.3
Caspersen, C.4
Jackson-Lewis, V.5
Carelli, V.6
Martinuzzi, A.7
Hirano, M.8
Przedborski, S.9
Vila, M.10
-
181
-
-
34249947154
-
Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease
-
Perier C, Bove J, Wu DC, Dehay B, Choi DK, Jackson-Lewis V, Rathke-HartliebS, Bouillet P, Strasser A, Schulz JB, et al. 2007. Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease. Proc Natl Acad Sci 104: 8161-8166.
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 8161-8166
-
-
Perier, C.1
Bove, J.2
Wu, D.C.3
Dehay, B.4
Choi, D.K.5
Jackson-Lewis, V.6
Rathke-Hartlieb, S.7
Bouillet, P.8
Strasser, A.9
Schulz, J.B.10
-
182
-
-
77955287517
-
Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins
-
Perier C, Bove J, Dehay B, Jackson-Lewis V, Rabinovitch PS, Przedborski S, VilaM. 2010. Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins. Ann Neurol 68: 184-192.
-
(2010)
Ann Neurol
, vol.68
, pp. 184-192
-
-
Perier, C.1
Bove, J.2
Dehay, B.3
Jackson-Lewis, V.4
Rabinovitch, P.S.5
Przedborski, S.6
Vila, M.7
-
183
-
-
84857968555
-
Mitochondria and programmed cell death in Parkinson's disease: Apoptosis and beyond
-
Perier C, Bove J, Vila M. 2011. Mitochondria and programmed cell death in Parkinson's disease: Apoptosis and beyond. Antioxid Redox Signal 16: 883-895.
-
(2011)
Antioxid Redox Signal
, vol.16
, pp. 883-895
-
-
Perier, C.1
Bove, J.2
Vila, M.3
-
184
-
-
2542560342
-
Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
-
Pesah Y, Pham T, Burgess H, Middlebrooks B, Verstreken P, Zhou Y, Harding M, Bellen H, Mardon G. 2004. Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress. Development 131:2183-2194.
-
(2004)
Development
, vol.131
, pp. 2183-2194
-
-
Pesah, Y.1
Pham, T.2
Burgess, H.3
Middlebrooks, B.4
Verstreken, P.5
Zhou, Y.6
Harding, M.7
Bellen, H.8
Mardon, G.9
-
185
-
-
79952792272
-
Programmed cell death: Apoptosis meets necrosis
-
Peter ME. 2011. Programmed cell death: Apoptosis meets necrosis. Nature 471: 310-312.
-
(2011)
Nature
, vol.471
, pp. 310-312
-
-
Peter, M.E.1
-
186
-
-
26644440926
-
Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations
-
Petit A, Kawarai T, Paitel E, Sanjo N, Maj M, Scheid M, Chen F, Gu Y, HasegawaH, Salehi-Rad S, et al. 2005. Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. J Biol Chem 280: 34025-34032.
-
(2005)
J Biol Chem
, vol.280
, pp. 34025-34032
-
-
Petit, A.1
Kawarai, T.2
Paitel, E.3
Sanjo, N.4
Maj, M.5
Scheid, M.6
Chen, F.7
Gu, Y.8
Hasegawa, H.9
Salehi-Rad, S.10
-
187
-
-
39549117093
-
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
-
Plowey ED, Cherra SJ III., Liu YJ, Chu CT. 2008. Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells. J Neurochem 105: 1048-1056.
-
(2008)
J Neurochem
, vol.105
, pp. 1048-1056
-
-
Plowey, E.D.1
Cherra III, S.J.2
Liu, Y.J.3
Chu, C.T.4
-
188
-
-
34547127902
-
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
-
Pridgeon JW, Olzmann JA, Chin LS, Li L. 2007. PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. PLoS Biol 5: e172.
-
(2007)
PLoS Biol
, vol.5
-
-
Pridgeon, J.W.1
Olzmann, J.A.2
Chin, L.S.3
Li, L.4
-
189
-
-
0037713489
-
The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: A tool to explore the pathogenesis of Parkinson's disease
-
Przedborski S, Vila M. 2003. The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: A tool to explore the pathogenesis of Parkinson's disease. Ann NY Acad Sci 991: 189-198.
-
(2003)
Ann NY Acad Sci
, vol.991
, pp. 189-198
-
-
Przedborski, S.1
Vila, M.2
-
190
-
-
0035053624
-
Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis
-
Putcha GV, Moulder KL, Golden JP, Bouillet P, Adams JA, Strasser A, JohnsonEM. 2001. Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron 29: 615-628.
-
(2001)
Neuron
, vol.29
, pp. 615-628
-
-
Putcha, G.V.1
Moulder, K.L.2
Golden, J.P.3
Bouillet, P.4
Adams, J.A.5
Strasser, A.6
Johnson, E.M.7
-
191
-
-
0037860975
-
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
-
Putcha GV, Le S, Frank S, Besirli CG, Clark K, Chu B, Alix S, Youle RJ, LaMarcheA, Maroney AC, et al. 2003. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron 38: 899-914.
-
(2003)
Neuron
, vol.38
, pp. 899-914
-
-
Putcha, G.V.1
Le, S.2
Frank, S.3
Besirli, C.G.4
Clark, K.5
Chu, B.6
Alix, S.7
Youle, R.J.8
LaMarche, A.9
Maroney, A.C.10
-
192
-
-
34250897267
-
Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease
-
Qu D, Rashidian J, Mount MP, Aleyasin H, Parsanejad M, Lira A, Haque E, ZhangY, Callaghan S, Daigle M, et al. 2007. Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease. Neuron 55: 37-52.
-
(2007)
Neuron
, vol.55
, pp. 37-52
-
-
Qu, D.1
Rashidian, J.2
Mount, M.P.3
Aleyasin, H.4
Parsanejad, M.5
Lira, A.6
Haque, E.7
Zhang, Y.8
Callaghan, S.9
Daigle, M.10
-
193
-
-
0037012844
-
Axonal self-destruction and neurodegeneration
-
Raff MC, Whitmore AV, Finn JT. 2002. Axonal self-destruction and neurodegeneration. Science 296: 868-871.
-
(2002)
Science
, vol.296
, pp. 868-871
-
-
Raff, M.C.1
Whitmore, A.V.2
Finn, J.T.3
-
194
-
-
79953758383
-
Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2
-
Ramonet D, Daher JP, Lin BM, Stafa K, Kim J, Banerjee R, Westerlund M, Pletnikova O, Glauser L, Yang L, et al. 2011. Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2. PloS ONE 6: e18568.
-
(2011)
PloS ONE
, vol.6
-
-
Ramonet, D.1
Daher, J.P.2
Lin, B.M.3
Stafa, K.4
Kim, J.5
Banerjee, R.6
Westerlund, M.7
Pletnikova, O.8
Glauser, L.9
Yang, L.10
-
195
-
-
17944366977
-
Heat-shock protein 70 antagonizes apoptosis-inducing factor
-
Ravagnan L, Gurbuxani S, Susin SA, Maisse C, Daugas E, Zamzami N, Mak T, Jaattela M, Penninger JM, Garrido C, et al. 2001. Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol 3: 839-843.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 839-843
-
-
Ravagnan, L.1
Gurbuxani, S.2
Susin, S.A.3
Maisse, C.4
Daugas, E.5
Zamzami, N.6
Mak, T.7
Jaattela, M.8
Penninger, J.M.9
Garrido, C.10
-
196
-
-
2642586352
-
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
-
Ravikumar B, Vacher C, Berger Z, Davies JE, Luo S, Oroz LG, Scaravilli F, EastonDF, Duden R, O'Kane CJ, et al. 2004. Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nat Genet 36: 585-595.
-
(2004)
Nat Genet
, vol.36
, pp. 585-595
-
-
Ravikumar, B.1
Vacher, C.2
Berger, Z.3
Davies, J.E.4
Luo, S.5
Oroz, L.G.6
Scaravilli, F.7
Easton, D.F.8
Duden, R.9
O'Kane, C.J.10
-
197
-
-
33645112812
-
Rapamycin pre-treatment protects against apoptosis
-
Ravikumar B, Berger Z, Vacher C, O'Kane CJ, Rubinsztein DC. 2006. Rapamycin pre-treatment protects against apoptosis. Hum Mol Genet 15: 1209-1216.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1209-1216
-
-
Ravikumar, B.1
Berger, Z.2
Vacher, C.3
O'Kane, C.J.4
Rubinsztein, D.C.5
-
198
-
-
77956231631
-
DJ-1, a cancer and Parkinson's disease associated protein, regulates autophagy through JNK pathway in cancer cells
-
Ren H, Fu K, Mu C, Li B, Wang D, Wang G. 2010. DJ-1, a cancer and Parkinson's disease associated protein, regulates autophagy through JNK pathway in cancer cells. Cancer Lett 297: 101-108.
-
(2010)
Cancer Lett
, vol.297
, pp. 101-108
-
-
Ren, H.1
Fu, K.2
Mu, C.3
Li, B.4
Wang, D.5
Wang, G.6
-
199
-
-
56749158302
-
JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration
-
Ries V, Silva RM, Oo TF, Cheng HC, Rzhetskaya M, Kholodilov N, Flavell RA, Kuan CY, Rakic P, Burke RE. 2008. JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration. J Neurochem 107: 1578-1588.
-
(2008)
J Neurochem
, vol.107
, pp. 1578-1588
-
-
Ries, V.1
Silva, R.M.2
Oo, T.F.3
Cheng, H.C.4
Rzhetskaya, M.5
Kholodilov, N.6
Flavell, R.A.7
Kuan, C.Y.8
Rakic, P.9
Burke, R.E.10
-
200
-
-
33644606491
-
Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes
-
Rodriguez-Enriquez S, Kim I, Currin RT, Lemasters JJ. 2006. Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy 2:39-46.
-
(2006)
Autophagy
, vol.2
, pp. 39-46
-
-
Rodriguez-Enriquez, S.1
Kim, I.2
Currin, R.T.3
Lemasters, J.J.4
-
202
-
-
0033821703
-
Induction of neuronal death by α-synuclein
-
Saha AR, Ninkina NN, Hanger DP, Anderton BH, Davies AM, Buchman VL.2000. Induction of neuronal death by α-synuclein. Eur J Neurosci 12:3073-3077.
-
(2000)
Eur J Neurosci
, vol.12
, pp. 3073-3077
-
-
Saha, A.R.1
Ninkina, N.N.2
Hanger, D.P.3
Anderton, B.H.4
Davies, A.M.5
Buchman, V.L.6
-
203
-
-
0033029823
-
CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons in vivo
-
Saporito MS, Brown EM, Miller MS, Carswell S. 1999. CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons in vivo. J Pharmacol Exp Ther 288: 421-427.
-
(1999)
J Pharmacol Exp Ther
, vol.288
, pp. 421-427
-
-
Saporito, M.S.1
Brown, E.M.2
Miller, M.S.3
Carswell, S.4
-
204
-
-
0037418843
-
BAX and BAK regulation of endoplasmic reticulum Ca2+: A control point for apoptosis
-
Scorrano L, Oakes SA, Opferman JT, Cheng EH, Sorcinelli MD, Pozzan T, Korsmeyer SJ. 2003. BAX and BAK regulation of endoplasmic reticulum Ca2+: A control point for apoptosis. Science 300: 135-139.
-
(2003)
Science
, vol.300
, pp. 135-139
-
-
Scorrano, L.1
Oakes, S.A.2
Opferman, J.T.3
Cheng, E.H.4
Sorcinelli, M.D.5
Pozzan, T.6
Korsmeyer, S.J.7
-
205
-
-
0036832421
-
α-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway
-
Seo JH, Rah JC, Choi SH, Shin JK, Min K, Kim HS, Park CH, Kim S, Kim EM, LeeSH, et al. 2002. α-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway. FASEB J 16: 1826-1828.
-
(2002)
FASEB J
, vol.16
, pp. 1826-1828
-
-
Seo, J.H.1
Rah, J.C.2
Choi, S.H.3
Shin, J.K.4
Min, K.5
Kim, H.S.6
Park, C.H.7
Kim, S.8
Kim, E.M.9
Lee, S.H.10
-
206
-
-
20844463252
-
Regulation of neuronal cell death and neurodegeneration by members of the Bcl-2 family: Therapeutic implications
-
Shacka JJ, Roth KA. 2005. Regulation of neuronal cell death and neurodegeneration by members of the Bcl-2 family: Therapeutic implications. Curr Drug Targets CNS Neurol Disord 4: 25-39.
-
(2005)
Curr Drug Targets CNS Neurol Disord
, vol.4
, pp. 25-39
-
-
Shacka, J.J.1
Roth, K.A.2
-
207
-
-
34548170490
-
Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis
-
Shen T, Zheng M, Cao C, Chen C, Tang J, Zhang W, Cheng H, Chen KH, Xiao RP.2007. Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis. J Biol Chem 282: 23354-23361.
-
(2007)
J Biol Chem
, vol.282
, pp. 23354-23361
-
-
Shen, T.1
Zheng, M.2
Cao, C.3
Chen, C.4
Tang, J.5
Zhang, W.6
Cheng, H.7
Chen, K.H.8
Xiao, R.P.9
-
208
-
-
84856056846
-
Mitochondrial transport in neurons: Impact on synaptic homeostasis and neurodegeneration
-
Sheng ZH, Cai Q. 2012. Mitochondrial transport in neurons: Impact on synaptic homeostasis and neurodegeneration. Nat Rev Neurosci 13: 77-93.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 77-93
-
-
Sheng, Z.H.1
Cai, Q.2
-
209
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
-
Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, Thompson CB, Tsujimoto Y. 2004. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 6: 1221-1228.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1221-1228
-
-
Shimizu, S.1
Kanaseki, T.2
Mizushima, N.3
Mizuta, T.4
Arakawa-Kobayashi, S.5
Thompson, C.B.6
Tsujimoto, Y.7
-
210
-
-
33645002036
-
Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities
-
Shinbo Y, Niki T, Taira T, Ooe H, Takahashi-Niki K, Maita C, Seino C, Iguchi-Ariga SM, Ariga H. 2006. Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities. Cell Death Diff 13: 96-108.
-
(2006)
Cell Death Diff
, vol.13
, pp. 96-108
-
-
Shinbo, Y.1
Niki, T.2
Taira, T.3
Ooe, H.4
Takahashi-Niki, K.5
Maita, C.6
Seino, C.7
Iguchi-Ariga, S.M.8
Ariga, H.9
-
211
-
-
28244466782
-
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism
-
Silva RM, Ries V, Oo TF, Yarygina O, Jackson-Lewis V, Ryu EJ, Lu PD, MarciniakSJ, Ron D, Przedborski S, et al. 2005. CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. J Neurochem 95: 974-986.
-
(2005)
J Neurochem
, vol.95
, pp. 974-986
-
-
Silva, R.M.1
Ries, V.2
Oo, T.F.3
Yarygina, O.4
Jackson-Lewis, V.5
Ryu, E.J.6
Lu, P.D.7
Marciniak, S.J.8
Ron, D.9
Przedborski, S.10
-
212
-
-
67650070391
-
Gene expression profiling of substantia nigra dopamine neurons: Further insights into Parkinson's disease pathology
-
Simunovic F, Yi M, Wang Y, Macey L, Brown LT, Krichevsky AM, Andersen SL, Stephens RM, Benes FM, Sonntag KC. 2009. Gene expression profiling of substantia nigra dopamine neurons: Further insights into Parkinson's disease pathology. Brain J Neurol 132: 1795-1809.
-
(2009)
Brain J Neurol
, vol.132
, pp. 1795-1809
-
-
Simunovic, F.1
Yi, M.2
Wang, Y.3
Macey, L.4
Brown, L.T.5
Krichevsky, A.M.6
Andersen, S.L.7
Stephens, R.M.8
Benes, F.M.9
Sonntag, K.C.10
-
213
-
-
0344823864
-
Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease
-
Smith PD, Crocker SJ, Jackson-Lewis V, Jordan-Sciutto KL, Hayley S, MountMP, O'Hare MJ, Callaghan S, Slack RS, Przedborski S, et al. 2003. Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease. Proc Natl Acad Sci 100: 13650-13655.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 13650-13655
-
-
Smith, P.D.1
Crocker, S.J.2
Jackson-Lewis, V.3
Jordan-Sciutto, K.L.4
Hayley, S.5
Mount, M.P.6
O'Hare, M.J.7
Callaghan, S.8
Slack, R.S.9
Przedborski, S.10
-
214
-
-
32544441845
-
Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2
-
Smith PD, Mount MP, Shree R, Callaghan S, Slack RS, Anisman H, Vincent I, Wang X, Mao Z, Park DS. 2006. Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2. J Neurosci 26: 440-447.
-
(2006)
J Neurosci
, vol.26
, pp. 440-447
-
-
Smith, P.D.1
Mount, M.P.2
Shree, R.3
Callaghan, S.4
Slack, R.S.5
Anisman, H.6
Vincent, I.7
Wang, X.8
Mao, Z.9
Park, D.S.10
-
215
-
-
77953485582
-
Synphilin-1 attenuates neuronal degeneration in the A53T α-synuclein transgenic mouse model
-
Smith WW, Liu Z, Liang Y, Masuda N, Swing DA, Jenkins NA, Copeland NG, Troncoso JC, Pletnikov M, Dawson TM, et al. 2010. Synphilin-1 attenuates neuronal degeneration in the A53T α-synuclein transgenic mouse model. Human Mol Genet 19: 2087-2098.
-
(2010)
Human Mol Genet
, vol.19
, pp. 2087-2098
-
-
Smith, W.W.1
Liu, Z.2
Liang, Y.3
Masuda, N.4
Swing, D.A.5
Jenkins, N.A.6
Copeland, N.G.7
Troncoso, J.C.8
Pletnikov, M.9
Dawson, T.M.10
-
216
-
-
72549085096
-
Transcription-independent p53 apoptosis: An alternative route to death
-
Speidel D. 2010. Transcription-independent p53 apoptosis: An alternative route to death. Trends Cell Biol 20: 14-24.
-
(2010)
Trends Cell Biol
, vol.20
, pp. 14-24
-
-
Speidel, D.1
-
217
-
-
0037422010
-
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
-
Staropoli JF, McDermott C, Martinat C, Schulman B, Demireva E, Abeliovich A.2003. Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity. Neuron 37: 735-749.
-
(2003)
Neuron
, vol.37
, pp. 735-749
-
-
Staropoli, J.F.1
McDermott, C.2
Martinat, C.3
Schulman, B.4
Demireva, E.5
Abeliovich, A.6
-
218
-
-
45349094984
-
Mitochondrial dynamics and apoptosis
-
Suen DF, Norris KL, Youle RJ. 2008. Mitochondrial dynamics and apoptosis. Genes Dev 22: 1577-1590.
-
(2008)
Genes Dev
, vol.22
, pp. 1577-1590
-
-
Suen, D.F.1
Norris, K.L.2
Youle, R.J.3
-
219
-
-
53149133169
-
Serine 129 phosphorylation of α-synuclein induces unfolded protein response-mediated cell death
-
Sugeno N, Takeda A, Hasegawa T, Kobayashi M, Kikuchi A, Mori F, Wakabayashi K, Itoyama Y. 2008. Serine 129 phosphorylation of α-synuclein induces unfolded protein response-mediated cell death. J Biol Chem 283:23179-23188.
-
(2008)
J Biol Chem
, vol.283
, pp. 23179-23188
-
-
Sugeno, N.1
Takeda, A.2
Hasegawa, T.3
Kobayashi, M.4
Kikuchi, A.5
Mori, F.6
Wakabayashi, K.7
Itoyama, Y.8
-
220
-
-
77956095537
-
Mitochondria and cell death: Outer membrane permeabilization and beyond
-
Tait SW, Green DR. 2010. Mitochondria and cell death: Outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol 11: 621-632.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 621-632
-
-
Tait, S.W.1
Green, D.R.2
-
221
-
-
0032531980
-
Involvement of caspase-like proteinases in apoptosis of neuronal PC12 cells and primary cultured microglia induced by 6-hydroxydopamine
-
Takai N, Nakanishi H, Tanabe K, Nishioku T, Sugiyama T, Fujiwara M, Yamamoto K. 1998. Involvement of caspase-like proteinases in apoptosis of neuronal PC12 cells and primary cultured microglia induced by 6-hydroxydopamine. J Neurosci Res 54: 214-222.
-
(1998)
J Neurosci Res
, vol.54
, pp. 214-222
-
-
Takai, N.1
Nakanishi, H.2
Tanabe, K.3
Nishioku, T.4
Sugiyama, T.5
Fujiwara, M.6
Yamamoto, K.7
-
222
-
-
0035870881
-
Inducible expression of mutant α-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
-
Tanaka Y, Engelender S, Igarashi S, Rao RK, Wanner T, Tanzi RE, Sawa AVLD, Dawson TM, Ross CA. 2001. Inducible expression of mutant α-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Human Mol Genet 10: 919-926.
-
(2001)
Human Mol Genet
, vol.10
, pp. 919-926
-
-
Tanaka, Y.1
Engelender, S.2
Igarashi, S.3
Rao, R.K.4
Wanner, T.5
Tanzi, R.E.6
Sawa, A.V.L.D.7
Dawson, T.M.8
Ross, C.A.9
-
223
-
-
78650729600
-
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
-
Tanaka A, Cleland MM, Xu S, Narendra DP, Suen DF, Karbowski M, Youle RJ.2010. Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J Cell Biol 191: 1367-1380.
-
(2010)
J Cell Biol
, vol.191
, pp. 1367-1380
-
-
Tanaka, A.1
Cleland, M.M.2
Xu, S.3
Narendra, D.P.4
Suen, D.F.5
Karbowski, M.6
Youle, R.J.7
-
224
-
-
44649141966
-
Regulation of autophagy by cytoplasmic 53
-
Tasdemir E, Maiuri MC, Galluzzi L, Vitale I, Djavaheri-Mergny M, D'Amelio M, Criollo A, Morselli E, Zhu C, Harper F, et al. 2008. Regulation of autophagy by cytoplasmic 53. Nat Cell Biol 10: 676-687.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 676-687
-
-
Tasdemir, E.1
Maiuri, M.C.2
Galluzzi, L.3
Vitale, I.4
Djavaheri-Mergny, M.5
D'Amelio, M.6
Criollo, A.7
Morselli, E.8
Zhu, C.9
Harper, F.10
-
225
-
-
0033756901
-
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
-
Tatton NA. 2000. Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease. Exp Neurol 166: 29-43.
-
(2000)
Exp Neurol
, vol.166
, pp. 29-43
-
-
Tatton, N.A.1
-
226
-
-
0030888286
-
In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
-
Tatton NA, Kish SJ. 1997. In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining. Neuroscience 77: 1037-1048.
-
(1997)
Neuroscience
, vol.77
, pp. 1037-1048
-
-
Tatton, N.A.1
Kish, S.J.2
-
227
-
-
0031696403
-
A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease
-
Tatton NA, Maclean-Fraser A, Tatton WG, Perl DP, Olanow CW. 1998. A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease. Ann Neurol 44: S142-148.
-
(1998)
Ann Neurol
, vol.44
-
-
Tatton, N.A.1
McLean-Fraser, A.2
Tatton, W.G.3
Perl, D.P.4
Olanow, C.W.5
-
228
-
-
0037378897
-
Apoptosis in Parkinson's disease: Signals for neuronal degradation
-
discussion S70-62
-
Tatton WG, Chalmers-Redman R, Brown D, Tatton N. 2003. Apoptosis in Parkinson's disease: Signals for neuronal degradation. Ann Neurol 53: S61-70;discussion S70-62.
-
(2003)
Ann Neurol
, vol.53
-
-
Tatton, W.G.1
Chalmers-Redman, R.2
Brown, D.3
Tatton, N.4
-
229
-
-
79956323688
-
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
-
Thomas KJ, McCoy MK, Blackinton J, Beilina A, van der Brug M, Sandebring A, Miller D, Maric D, Cedazo-Minguez A, Cookson MR. 2011. DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. Human Mol Genet 20: 40-50.
-
(2011)
Human Mol Genet
, vol.20
, pp. 40-50
-
-
Thomas, K.J.1
McCoy, M.K.2
Blackinton, J.3
Beilina, A.4
van der Brug, M.5
Sandebring, A.6
Miller, D.7
Maric, D.8
Cedazo-Minguez, A.9
Cookson, M.R.10
-
230
-
-
0031013141
-
Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons
-
Tompkins MM, Basgall EJ, Zamrini E, Hill WD. 1997. Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons. Am J Pathol 150: 119-131.
-
(1997)
Am J Pathol
, vol.150
, pp. 119-131
-
-
Tompkins, M.M.1
Basgall, E.J.2
Zamrini, E.3
Hill, W.D.4
-
231
-
-
77953090478
-
Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice
-
Tong Y, Yamaguchi H, Giaime E, Boyle S, Kopan R, Kelleher RJ 3rd., Shen J.2010. Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice. Proc Natl Acad Sci 107: 9879-9884.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 9879-9884
-
-
Tong, Y.1
Yamaguchi, H.2
Giaime, E.3
Boyle, S.4
Kopan, R.5
Kelleher III, R.J.6
Shen, J.7
-
232
-
-
0034607702
-
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
-
Tournier C, Hess P, Yang DD, Xu J, Turner TK, Nimnual A, Bar-Sagi D, JonesSN, Flavell RA, Davis RJ. 2000. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 288: 870-874.
-
(2000)
Science
, vol.288
, pp. 870-874
-
-
Tournier, C.1
Hess, P.2
Yang, D.D.3
Xu, J.4
Turner, T.K.5
Nimnual, A.6
Bar-Sagi, D.7
Jones, S.N.8
Flavell, R.A.9
Davis, R.J.10
-
233
-
-
0030249597
-
Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity
-
Trimmer PA, Smith TS, Jung AB, Bennett JP Jr. 1996. Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity. Neurodegeneration 5: 233-239.
-
(1996)
Neurodegeneration
, vol.5
, pp. 233-239
-
-
Trimmer, P.A.1
Smith, T.S.2
Jung, A.B.3
Bennett Jr., J.P.4
-
234
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, et al. 2008. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J 27: 433-446.
-
(2008)
EMBO J
, vol.27
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
-
235
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente EM, Abou-Sleiman PM, Caputo V, Muqit MM, Harvey K, Gispert S, Ali Z, Del Turco D, Bentivoglio AR, Healy DG, et al. 2004. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304: 1158-1160.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
-
237
-
-
33749453510
-
Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease
-
Vercammen L, Van der Perren A, Vaudano E, Gijsbers R, Debyser Z, Van den Haute C, Baekelandt V. 2006. Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease. Mol Therapy J Am Soc Gene Therapy 14: 716-723.
-
(2006)
Mol Therapy J Am Soc Gene Therapy
, vol.14
, pp. 716-723
-
-
Vercammen, L.1
Van der Perren, A.2
Vaudano, E.3
Gijsbers, R.4
Debyser, Z.5
Van den Haute, C.6
Baekelandt, V.7
-
238
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen AM, Ekert PG, Pakusch M, Silke J, Connolly LM, Reid GE, Moritz RL, Simpson RJ, Vaux DL. 2000. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 102:43-53.
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
Moritz, R.L.7
Simpson, R.J.8
Vaux, D.L.9
-
239
-
-
0035956874
-
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
-
Vila M, Jackson-Lewis V, Vukosavic S, Djaldetti R, Liberatore G, Offen D, Korsmeyer SJ, Przedborski S. 2001. Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. Proc Natl Acad Sci 98: 2837-2842.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 2837-2842
-
-
Vila, M.1
Jackson-Lewis, V.2
Vukosavic, S.3
Djaldetti, R.4
Liberatore, G.5
Offen, D.6
Korsmeyer, S.J.7
Przedborski, S.8
-
240
-
-
0242410719
-
p53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
-
Villunger A, Michalak EM, Coultas L, Mullauer F, Bock G, Ausserlechner MJ, Adams JM, Strasser A. 2003. p53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 302: 1036-1038.
-
(2003)
Science
, vol.302
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
Mullauer, F.4
Bock, G.5
Ausserlechner, M.J.6
Adams, J.M.7
Strasser, A.8
-
241
-
-
0035894881
-
Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease
-
Viswanath V, Wu Y, Boonplueang R, Chen S, Stevenson FF, Yantiri F, Yang L, Beal MF, Andersen JK. 2001. Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease. J Neurosci 21: 9519-9528.
-
(2001)
J Neurosci
, vol.21
, pp. 9519-9528
-
-
Viswanath, V.1
Wu, Y.2
Boonplueang, R.3
Chen, S.4
Stevenson, F.F.5
Yantiri, F.6
Yang, L.7
Beal, M.F.8
Andersen, J.K.9
-
242
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, Kim J, May J, TocilescuMA, Liu W, Ko HS, et al. 2010. PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc Natl Acad Sci 107: 378-383.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
de Vries, R.L.5
Kim, J.6
May, J.7
Tocilescu, M.A.8
Liu, W.9
Ko, H.S.10
-
243
-
-
53749096967
-
Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration
-
Vosler PS, Brennan CS, Chen J. 2008. Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration. Mol Neurobiol 38: 78-100.
-
(2008)
Mol Neurobiol
, vol.38
, pp. 78-100
-
-
Vosler, P.S.1
Brennan, C.S.2
Chen, J.3
-
244
-
-
0030906885
-
Expression of Bcl-2 in adult human brain regions with special reference to neurodegenerative disorders
-
Vyas S, Javoy-Agid F, Herrero MT, Strada O, Boissiere F, Hibner U, Agid Y.1997. Expression of Bcl-2 in adult human brain regions with special reference to neurodegenerative disorders. J Neurochem 69: 223-231.
-
(1997)
J Neurochem
, vol.69
, pp. 223-231
-
-
Vyas, S.1
Javoy-Agid, F.2
Herrero, M.T.3
Strada, O.4
Boissiere, F.5
Hibner, U.6
Agid, Y.7
-
245
-
-
33750207744
-
Recent clinical failures in Parkinson's disease with apoptosis inhibitors underline the need for a paradigm shift in drug discovery for neurodegenerative diseases
-
Waldmeier P, Bozyczko-Coyne D, Williams M, Vaught JL. 2006. Recent clinical failures in Parkinson's disease with apoptosis inhibitors underline the need for a paradigm shift in drug discovery for neurodegenerative diseases. Biochem Pharmacol 72: 1197-1206.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1197-1206
-
-
Waldmeier, P.1
Bozyczko-Coyne, D.2
Williams, M.3
Vaught, J.L.4
-
246
-
-
0037713529
-
Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease
-
Wang H, Shimoji M, Yu SW, Dawson TM, Dawson VL. 2003. Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease. Ann NY Acad Sci 991: 132-139.
-
(2003)
Ann NY Acad Sci
, vol.991
, pp. 132-139
-
-
Wang, H.1
Shimoji, M.2
Yu, S.W.3
Dawson, T.M.4
Dawson, V.L.5
-
247
-
-
35349030746
-
PINK1 mutants associated with recessive Parkinson's disease are defective in inhibiting mitochondrial release of cytochrome c
-
Wang HL, Chou AH, Yeh TH, Li AH, Chen YL, Kuo YL, Tsai SR, Yu ST. 2007. PINK1 mutants associated with recessive Parkinson's disease are defective in inhibiting mitochondrial release of cytochrome c. Neurobiol Dis 28: 216-226.
-
(2007)
Neurobiol Dis
, vol.28
, pp. 216-226
-
-
Wang, H.L.1
Chou, A.H.2
Yeh, T.H.3
Li, A.H.4
Chen, Y.L.5
Kuo, Y.L.6
Tsai, S.R.7
Yu, S.T.8
-
248
-
-
79954616687
-
PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons
-
Wang HL, Chou AH, Wu AS, Chen SY, Weng YH, Kao YC, Yeh TH, Chu PJ, Lu CS.2011a. PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons. Biochim Biophys Acta 1812: 674-684.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 674-684
-
-
Wang, H.L.1
Chou, A.H.2
Wu, A.S.3
Chen, S.Y.4
Weng, Y.H.5
Kao, Y.C.6
Yeh, T.H.7
Chu, P.J.8
Lu, C.S.9
-
249
-
-
81055140895
-
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility
-
Wang X, Winter D, Ashrafi G, Schlehe J, Wong YL, Selkoe D, Rice S, Steen J, LaVoie MJ, Schwarz TL. 2011b. PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 147: 893-906.
-
(2011)
Cell
, vol.147
, pp. 893-906
-
-
Wang, X.1
Winter, D.2
Ashrafi, G.3
Schlehe, J.4
Wong, Y.L.5
Selkoe, D.6
Rice, S.7
Steen, J.8
LaVoie, M.J.9
Schwarz, T.L.10
-
250
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, RothKA, MacGregor GR, Thompson CB, Korsmeyer SJ. 2001. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 292:727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
McGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
251
-
-
0142250831
-
Inhibition of CDK5 is protective in necrotic and apoptotic paradigms of neuronal cell death and prevents mitochondrial dysfunction
-
Weishaupt JH, Kussmaul L, Grotsch P, Heckel A, Rohde G, Romig H, Bahr M, Gillardon F. 2003. Inhibition of CDK5 is protective in necrotic and apoptotic paradigms of neuronal cell death and prevents mitochondrial dysfunction. Mol Cell Neurosci 24: 489-502.
-
(2003)
Mol Cell Neurosci
, vol.24
, pp. 489-502
-
-
Weishaupt, J.H.1
Kussmaul, L.2
Grotsch, P.3
Heckel, A.4
Rohde, G.5
Romig, H.6
Bahr, M.7
Gillardon, F.8
-
252
-
-
0035049449
-
Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release
-
Whitfield J, Neame SJ, Paquet L, Bernard O, Ham J. 2001. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron 29: 629-643.
-
(2001)
Neuron
, vol.29
, pp. 629-643
-
-
Whitfield, J.1
Neame, S.J.2
Paquet, L.3
Bernard, O.4
Ham, J.5
-
253
-
-
79953653114
-
The Parkinson disease protein α-synuclein inhibits autophagy
-
Winslow AR, Rubinsztein DC. 2011. The Parkinson disease protein α-synuclein inhibits autophagy. Autophagy 7: 429-431.
-
(2011)
Autophagy
, vol.7
, pp. 429-431
-
-
Winslow, A.R.1
Rubinsztein, D.C.2
-
254
-
-
46749117587
-
p53′s mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity
-
Wolff S, Erster S, Palacios G, Moll UM. 2008. p53′s mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity. Cell Res 18: 733-744.
-
(2008)
Cell Res
, vol.18
, pp. 733-744
-
-
Wolff, S.1
Erster, S.2
Palacios, G.3
Moll, U.M.4
-
255
-
-
85027948203
-
Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease
-
Wong AS, Lee RH, Cheung AY, Yeung PK, Chung SK, Cheung ZH, Ip NY. 2011. Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease. Nat Cell Biol 13: 568-579.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 568-579
-
-
Wong, A.S.1
Lee, R.H.2
Cheung, A.Y.3
Yeung, P.K.4
Chung, S.K.5
Cheung, Z.H.6
Ip, N.Y.7
-
256
-
-
0342331476
-
Cell death and apoptosis regulating proteins in Parkinson's disease-a cautionary note
-
Wullner U, Kornhuber J, Weller M, Schulz JB, Loschmann PA, Riederer P, Klockgether T. 1999. Cell death and apoptosis regulating proteins in Parkinson's disease-a cautionary note. Acta Neuropathol 97: 408-412.
-
(1999)
Acta Neuropathol
, vol.97
, pp. 408-412
-
-
Wullner, U.1
Kornhuber, J.2
Weller, M.3
Schulz, J.B.4
Loschmann, P.A.5
Riederer, P.6
Klockgether, T.7
-
257
-
-
0035964358
-
Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease
-
Xia XG, Harding T, Weller M, Bieneman A, Uney JB, Schulz JB. 2001. Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease. Proc Natl Acad Sci 98: 10433-10438.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 10433-10438
-
-
Xia, X.G.1
Harding, T.2
Weller, M.3
Bieneman, A.4
Uney, J.B.5
Schulz, J.B.6
-
258
-
-
0032519859
-
Bax involvement in p53-mediated neuronal cell death
-
Xiang H, Kinoshita Y, Knudson CM, Korsmeyer SJ, Schwartzkroin PA, MorrisonRS. 1998. Bax involvement in p53-mediated neuronal cell death. J Neurosci 18:1363-1373.
-
(1998)
J Neurosci
, vol.18
, pp. 1363-1373
-
-
Xiang, H.1
Kinoshita, Y.2
Knudson, C.M.3
Korsmeyer, S.J.4
Schwartzkroin, P.A.5
Morrison, R.S.6
-
259
-
-
26444442450
-
Endoplasmic reticulum stress: Cell life and death decisions
-
Xu C, Bailly-Maitre B, Reed JC. 2005a. Endoplasmic reticulum stress: Cell life and death decisions. J Clin Invest 115: 2656-2664.
-
(2005)
J Clin Invest
, vol.115
, pp. 2656-2664
-
-
Xu, C.1
Bailly-Maitre, B.2
Reed, J.C.3
-
260
-
-
20944437573
-
The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
-
Xu J, Zhong N, Wang H, Elias JE, Kim CY, Woldman I, Pifl C, Gygi SP, Geula C, Yankner BA. 2005b. The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis. Hum Mol Genet 14: 1231-1241.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1231-1241
-
-
Xu, J.1
Zhong, N.2
Wang, H.3
Elias, J.E.4
Kim, C.Y.5
Woldman, I.6
Pifl, C.7
Gygi, S.P.8
Geula, C.9
Yankner, B.A.10
-
261
-
-
23844506517
-
Selective alterations of transcription factors in MPP+-induced neurotoxicity in PC12 cells
-
Xu Z, Cawthon D, McCastlain KA, Duhart HM, Newport GD, Fang H, PattersonTA, Slikker W Jr., Ali SF. 2005c. Selective alterations of transcription factors in MPP+-induced neurotoxicity in PC12 cells. Neurotoxicology 26: 729-737.
-
(2005)
Neurotoxicology
, vol.26
, pp. 729-737
-
-
Xu, Z.1
Cawthon, D.2
McCastlain, K.A.3
Duhart, H.M.4
Newport, G.D.5
Fang, H.6
Patterson, T.A.7
Slikker Jr., W.8
Ali, S.F.9
-
262
-
-
13544251757
-
Mechanisms of neural cell death: Implications for development of neuroprotective treatment strategies
-
Yakovlev AG, Faden AI. 2004. Mechanisms of neural cell death: Implications for development of neuroprotective treatment strategies. NeuroRx 1: 5-16.
-
(2004)
NeuroRx
, vol.1
, pp. 5-16
-
-
Yakovlev, A.G.1
Faden, A.I.2
-
263
-
-
0033616576
-
Herpes simplex virus vector-mediated expression of Bcl-2 prevents 6-hydroxydopamine-induced degeneration of neurons in the substantia nigra in vivo
-
Yamada M, Oligino T, Mata M, Goss JR, Glorioso JC, Fink DJ. 1999. Herpes simplex virus vector-mediated expression of Bcl-2 prevents 6-hydroxydopamine-induced degeneration of neurons in the substantia nigra in vivo. Proc Natl Acad Sci 96: 4078-4083.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 4078-4083
-
-
Yamada, M.1
Oligino, T.2
Mata, M.3
Goss, J.R.4
Glorioso, J.C.5
Fink, D.J.6
-
264
-
-
33745070550
-
Involvement of endoplasmic reticulum stress on the cell death induced by 6-hydroxydopamine in human neuroblastoma SH-SY5Y cells
-
Yamamuro A, Yoshioka Y, Ogita K, Maeda S. 2006. Involvement of endoplasmic reticulum stress on the cell death induced by 6-hydroxydopamine in human neuroblastoma SH-SY5Y cells. Neurochem Res 31: 657-664.
-
(2006)
Neurochem Res
, vol.31
, pp. 657-664
-
-
Yamamuro, A.1
Yoshioka, Y.2
Ogita, K.3
Maeda, S.4
-
265
-
-
0028809209
-
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death
-
Yang E, Zha J, Jockel J, Boise LH, Thompson CB, Korsmeyer SJ. 1995. Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell 80: 285-291.
-
(1995)
Cell
, vol.80
, pp. 285-291
-
-
Yang, E.1
Zha, J.2
Jockel, J.3
Boise, L.H.4
Thompson, C.B.5
Korsmeyer, S.J.6
-
266
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, Peng TI, Jones DP, Wang X.1997a. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Science 275: 1129-1132.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
Peng, T.I.7
Jones, D.P.8
Wang, X.9
-
267
-
-
0031587883
-
Daxx, a novel Fas-binding protein that activates JNK and apoptosis
-
Yang X, Khosravi-Far R, Chang HY, Baltimore D. 1997b. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 89: 1067-1076.
-
(1997)
Cell
, vol.89
, pp. 1067-1076
-
-
Yang, X.1
Khosravi-Far, R.2
Chang, H.Y.3
Baltimore, D.4
-
268
-
-
0032531886
-
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2
-
Yang L, Matthews RT, Schulz JB, Klockgether T, Liao AW, Martinou JC, PenneyJB Jr., Hyman BT, Beal MF. 1998. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2. J Neurosci 18:8145-8152.
-
(1998)
J Neurosci
, vol.18
, pp. 8145-8152
-
-
Yang, L.1
Matthews, R.T.2
Schulz, J.B.3
Klockgether, T.4
Liao, A.W.5
Martinou, J.C.6
Penney Jr., J.B.7
Hyman, B.T.8
Beal, M.F.9
-
269
-
-
26444489693
-
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
-
Yang Y, Gehrke S, Haque ME, Imai Y, Kosek J, Yang L, Beal MF, Nishimura I, Wakamatsu K, Ito S, et al. 2005. Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci 102: 13670-13675.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 13670-13675
-
-
Yang, Y.1
Gehrke, S.2
Haque, M.E.3
Imai, Y.4
Kosek, J.5
Yang, L.6
Beal, M.F.7
Nishimura, I.8
Wakamatsu, K.9
Ito, S.10
-
270
-
-
33746080412
-
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
-
Yang Y, Gehrke S, Imai Y, Huang Z, Ouyang Y, Wang JW, Yang L, Beal MF, VogelH, Lu B. 2006. Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc Natl Acad Sci 103: 10793-10798.
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 10793-10798
-
-
Yang, Y.1
Gehrke, S.2
Imai, Y.3
Huang, Z.4
Ouyang, Y.5
Wang, J.W.6
Yang, L.7
Beal, M.F.8
Vogel, H.9
Lu, B.10
-
271
-
-
70449529426
-
Paraquat activates the IRE1/ASK1/JNK cascade associated with apoptosis in human neuroblastoma SH-SY5Y cells
-
Yang W, Tiffany-Castiglioni E, Koh HC, Son IH. 2009. Paraquat activates the IRE1/ASK1/JNK cascade associated with apoptosis in human neuroblastoma SH-SY5Y cells. Toxicol Lett 191: 203-210.
-
(2009)
Toxicol Lett
, vol.191
, pp. 203-210
-
-
Yang, W.1
Tiffany-Castiglioni, E.2
Koh, H.C.3
Son, I.H.4
-
272
-
-
0345357664
-
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition
-
Yokota T, Sugawara K, Ito K, Takahashi R, Ariga H, Mizusawa H. 2003. Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition. Biochem Biophys Res Commun 312: 1342-1348.
-
(2003)
Biochem Biophys Res Commun
, vol.312
, pp. 1342-1348
-
-
Yokota, T.1
Sugawara, K.2
Ito, K.3
Takahashi, R.4
Ariga, H.5
Mizusawa, H.6
-
273
-
-
77952038836
-
Poly(ADP-ribose)polymerase inhibitor can attenuate the neuronal death after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice
-
Yokoyama H, Kuroiwa H, Tsukada T, Uchida H, Kato H, Araki T. 2010. Poly(ADP-ribose)polymerase inhibitor can attenuate the neuronal death after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice. J Neurosci Res 88: 1522-1536.
-
(2010)
J Neurosci Res
, vol.88
, pp. 1522-1536
-
-
Yokoyama, H.1
Kuroiwa, H.2
Tsukada, T.3
Uchida, H.4
Kato, H.5
Araki, T.6
-
274
-
-
1842483241
-
Excitotoxic versus apoptotic mechanisms of neuronal cell death in perinatal hypoxia/ischemia
-
Young C, Tenkova T, Dikranian K, Olney JW. 2004. Excitotoxic versus apoptotic mechanisms of neuronal cell death in perinatal hypoxia/ischemia. Curr Mol Med 4: 77-85.
-
(2004)
Curr Mol Med
, vol.4
, pp. 77-85
-
-
Young, C.1
Tenkova, T.2
Dikranian, K.3
Olney, J.W.4
-
275
-
-
33749162486
-
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
-
Yousefi S, Perozzo R, Schmid I, Ziemiecki A, Schaffner T, Scapozza L, BrunnerT, Simon HU. 2006. Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol 8: 1124-1132.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1124-1132
-
-
Yousefi, S.1
Perozzo, R.2
Schmid, I.3
Ziemiecki, A.4
Schaffner, T.5
Scapozza, L.6
Brunner, T.7
Simon, H.U.8
-
276
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL. 2002. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297: 259-263.
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
Coombs, C.4
Bowers, W.J.5
Federoff, H.J.6
Poirier, G.G.7
Dawson, T.M.8
Dawson, V.L.9
-
277
-
-
33847048316
-
Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
-
Zhu JH, Horbinski C, Guo F, Watkins S, Uchiyama Y, Chu CT. 2007. Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death. Am J Pathol 170: 75-86.
-
(2007)
Am J Pathol
, vol.170
, pp. 75-86
-
-
Zhu, J.H.1
Horbinski, C.2
Guo, F.3
Watkins, S.4
Uchiyama, Y.5
Chu, C.T.6
-
278
-
-
77950384477
-
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
-
Ziviani E, Tao RN, Whitworth AJ. 2010. Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc Natl Acad Sci 107: 5018-5023.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 5018-5023
-
-
Ziviani, E.1
Tao, R.N.2
Whitworth, A.J.3
-
279
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB. 2001. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 15: 1481-1486.
-
(2001)
Genes Dev
, vol.15
, pp. 1481-1486
-
-
Zong, W.X.1
Lindsten, T.2
Ross, A.J.3
McGregor, G.R.4
Thompson, C.B.5
-
280
-
-
0037810844
-
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
-
Zong WX, Li C, Hatzivassiliou G, Lindsten T, Yu QC, Yuan J, Thompson CB.2003. Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis. J Cell Biol 162: 59-69.
-
(2003)
J Cell Biol
, vol.162
, pp. 59-69
-
-
Zong, W.X.1
Li, C.2
Hatzivassiliou, G.3
Lindsten, T.4
Yu, Q.C.5
Yuan, J.6
Thompson, C.B.7
-
281
-
-
2642536197
-
Alkylating DNA damage stimulates a regulated form of necrotic cell death
-
Zong WX, Ditsworth D, Bauer DE, Wang ZQ, Thompson CB. 2004. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 18:1272-1282.
-
(2004)
Genes Dev
, vol.18
, pp. 1272-1282
-
-
Zong, W.X.1
Ditsworth, D.2
Bauer, D.E.3
Wang, Z.Q.4
Thompson, C.B.5
-
282
-
-
0034694199
-
Time course of degenerative alterations in nigral dopaminergic neurons following a 6-hydroxydopamine lesion
-
Zuch CL, Nordstroem VK, Briedrick LA, Hoernig GR, Granholm AC, Bickford PC.2000. Time course of degenerative alterations in nigral dopaminergic neurons following a 6-hydroxydopamine lesion. J Comp Neurol 427: 440-454.
-
(2000)
J Comp Neurol
, vol.427
, pp. 440-454
-
-
Zuch, C.L.1
Nordstroem, V.K.2
Briedrick, L.A.3
Hoernig, G.R.4
Granholm, A.C.5
Bickford, P.C.6
|