Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 38, 2005, Pages 13670-13675

  Yang, Yufeng ^a   Gehrke, Stephan ^a   Haque, Md Emdadul ^a   Imai, Yuzuru ^a   Kosek, Jon ^a   Yang, Lichuan ^b   Beal, M Flint ^b   Nishimura, Isao ^c   Wakamatsu, Kazumasa ^d   Ito, Shosuke ^d   Takahashi, Ryosuke ^e   Lu, Bingwei ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c OSAKA UNIVERSITY   (Japan)

^d FUJITA HEALTH UNIVERSITY   (Japan)

^e RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

Parkinson's disease; PI3K PTEN Akt signaling; Reactive oxygen species

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; DJ1 GENE; DOPAMINERGIC SYSTEM; DROSOPHILA; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; GENE; GENE IDENTIFICATION; GENE INACTIVATION; GENE INTERACTION; MOLECULAR MODEL; MOTOR DYSFUNCTION; MUTATOR GENE; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PARKIN GENE; PARKINSON DISEASE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; DISEASE MODELS, ANIMAL; DOPAMINE; DROSOPHILA; DROSOPHILA PROTEINS; ENZYME ACTIVATION; HUMANS; OXIDATIVE STRESS; PARKINSON DISEASE; PHOTORECEPTORS, INVERTEBRATE; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

ANIMALIA; MAMMALIA;

EID: 26444489693     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0504610102     Document Type: Article

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