-
1
-
-
0033772264
-
OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28
-
Alexander C., Votruba M., Pesch U.E., Thiselton D.L., Mayer S., Moore A., Rodriguez M., Kellner U., Leo-Kottler B., Auburger G., et al. OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28. Nat. Genet. 26 (2000) 211-215
-
(2000)
Nat. Genet.
, vol.26
, pp. 211-215
-
-
Alexander, C.1
Votruba, M.2
Pesch, U.E.3
Thiselton, D.L.4
Mayer, S.5
Moore, A.6
Rodriguez, M.7
Kellner, U.8
Leo-Kottler, B.9
Auburger, G.10
-
2
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
Bender A., Krishnan K.J., Morris C.M., Taylor G.A., Reeve A.K., Perry R.H., Jaros E., Hersheson J.S., Betts J., Klopstock T., et al. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat. Genet. 38 (2006) 515-517
-
(2006)
Nat. Genet.
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reeve, A.K.5
Perry, R.H.6
Jaros, E.7
Hersheson, J.S.8
Betts, J.9
Klopstock, T.10
-
3
-
-
0033194038
-
The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast
-
Bleazard W., McCaffery J.M., King E.J., Bale S., Mozdy A., Tieu Q., Nunnari J., and Shaw J.M. The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast. Nat. Cell Biol. 1 (1999) 298-304
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 298-304
-
-
Bleazard, W.1
McCaffery, J.M.2
King, E.J.3
Bale, S.4
Mozdy, A.5
Tieu, Q.6
Nunnari, J.7
Shaw, J.M.8
-
4
-
-
0028349236
-
Decline with age of the respiratory chain activity in human skeletal muscle
-
Boffoli D., Scacco S.C., Vergari R., Solarino G., Santacroce G., and Papa S. Decline with age of the respiratory chain activity in human skeletal muscle. Biochim. Biophys. Acta 1226 (1994) 73-82
-
(1994)
Biochim. Biophys. Acta
, vol.1226
, pp. 73-82
-
-
Boffoli, D.1
Scacco, S.C.2
Vergari, R.3
Solarino, G.4
Santacroce, G.5
Papa, S.6
-
5
-
-
0037417334
-
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol
-
Breckenridge D.G., Stojanovic M., Marcellus R.C., and Shore G.C. Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J. Cell Biol. 160 (2003) 1115-1127
-
(2003)
J. Cell Biol.
, vol.160
, pp. 1115-1127
-
-
Breckenridge, D.G.1
Stojanovic, M.2
Marcellus, R.C.3
Shore, G.C.4
-
8
-
-
0037455575
-
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
-
Chen H., Detmer S.A., Ewald A.J., Griffin E.E., Fraser S.E., and Chan D.C. Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J. Cell Biol. 160 (2003) 189-200
-
(2003)
J. Cell Biol.
, vol.160
, pp. 189-200
-
-
Chen, H.1
Detmer, S.A.2
Ewald, A.J.3
Griffin, E.E.4
Fraser, S.E.5
Chan, D.C.6
-
9
-
-
22544451586
-
Disruption of fusion results in mitochondrial heterogeneity and dysfunction
-
Chen H., Chomyn A., and Chan D.C. Disruption of fusion results in mitochondrial heterogeneity and dysfunction. J. Biol. Chem. 280 (2005) 26185-26192
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 26185-26192
-
-
Chen, H.1
Chomyn, A.2
Chan, D.C.3
-
12
-
-
0026469073
-
Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing
-
Cooper J.M., Mann V.M., and Schapira A.H. Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing. J. Neurol. Sci. 113 (1992) 91-98
-
(1992)
J. Neurol. Sci.
, vol.113
, pp. 91-98
-
-
Cooper, J.M.1
Mann, V.M.2
Schapira, A.H.3
-
13
-
-
11044238456
-
Heterologous mitochondrial DNA recombination in human cells
-
D'Aurelio M., Gajewski C.D., Lin M.T., Mauck W.M., Shao L.Z., Lenaz G., Moraes C.T., and Manfredi G. Heterologous mitochondrial DNA recombination in human cells. Hum. Mol. Genet. 13 (2004) 3171-3179
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 3171-3179
-
-
D'Aurelio, M.1
Gajewski, C.D.2
Lin, M.T.3
Mauck, W.M.4
Shao, L.Z.5
Lenaz, G.6
Moraes, C.T.7
Manfredi, G.8
-
14
-
-
20244381365
-
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy
-
Delettre C., Lenaers G., Griffoin J.M., Gigarel N., Lorenzo C., Belenguer P., Pelloquin L., Grosgeorge J., Turc-Carel C., Perret E., et al. Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy. Nat. Genet. 26 (2000) 207-210
-
(2000)
Nat. Genet.
, vol.26
, pp. 207-210
-
-
Delettre, C.1
Lenaers, G.2
Griffoin, J.M.3
Gigarel, N.4
Lorenzo, C.5
Belenguer, P.6
Pelloquin, L.7
Grosgeorge, J.8
Turc-Carel, C.9
Perret, E.10
-
15
-
-
0036369531
-
OPA1 (Kjer type) dominant optic atrophy: a novel mitochondrial disease
-
Delettre C., Lenaers G., Pelloquin L., Belenguer P., and Hamel C.P. OPA1 (Kjer type) dominant optic atrophy: a novel mitochondrial disease. Mol. Genet. Metab. 75 (2002) 97-107
-
(2002)
Mol. Genet. Metab.
, vol.75
, pp. 97-107
-
-
Delettre, C.1
Lenaers, G.2
Pelloquin, L.3
Belenguer, P.4
Hamel, C.P.5
-
16
-
-
0037972522
-
Mitochondrial respiratory-chain diseases
-
DiMauro S., and Schon E.A. Mitochondrial respiratory-chain diseases. N. Engl. J. Med. 348 (2003) 2656-2668
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 2656-2668
-
-
DiMauro, S.1
Schon, E.A.2
-
17
-
-
20344366079
-
Mitochondrial DNA and disease
-
Dimauro S., and Davidzon G. Mitochondrial DNA and disease. Ann. Med. 37 (2005) 222-232
-
(2005)
Ann. Med.
, vol.37
, pp. 222-232
-
-
Dimauro, S.1
Davidzon, G.2
-
18
-
-
0035487808
-
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
-
Frank S., Gaume B., Bergmann-Leitner E.S., Leitner W.W., Robert E.G., Catez F., Smith C.L., and Youle R.J. The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev. Cell 1 (2001) 515-525
-
(2001)
Dev. Cell
, vol.1
, pp. 515-525
-
-
Frank, S.1
Gaume, B.2
Bergmann-Leitner, E.S.3
Leitner, W.W.4
Robert, E.G.5
Catez, F.6
Smith, C.L.7
Youle, R.J.8
-
19
-
-
0037458579
-
Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis
-
Fransson A., Ruusala A., and Aspenstrom P. Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis. J. Biol. Chem. 278 (2003) 6495-6502
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 6495-6502
-
-
Fransson, A.1
Ruusala, A.2
Aspenstrom, P.3
-
20
-
-
5444257615
-
Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway
-
Frederick R.L., McCaffery J.M., Cunningham K.W., Okamoto K., and Shaw J.M. Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway. J. Cell Biol. 167 (2004) 87-98
-
(2004)
J. Cell Biol.
, vol.167
, pp. 87-98
-
-
Frederick, R.L.1
McCaffery, J.M.2
Cunningham, K.W.3
Okamoto, K.4
Shaw, J.M.5
-
21
-
-
0038709292
-
Composition and dynamics of human mitochondrial nucleoids
-
Garrido N., Griparic L., Jokitalo E., Wartiovaara J., van der Bliek A.M., and Spelbrink J.N. Composition and dynamics of human mitochondrial nucleoids. Mol. Biol. Cell 14 (2003) 1583-1596
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 1583-1596
-
-
Garrido, N.1
Griparic, L.2
Jokitalo, E.3
Wartiovaara, J.4
van der Bliek, A.M.5
Spelbrink, J.N.6
-
22
-
-
22944440071
-
The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria
-
Griffin E.E., Graumann J., and Chan D.C. The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria. J. Cell Biol. 170 (2005) 237-248
-
(2005)
J. Cell Biol.
, vol.170
, pp. 237-248
-
-
Griffin, E.E.1
Graumann, J.2
Chan, D.C.3
-
23
-
-
2442421118
-
Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria
-
Griparic L., van der Wel N.N., Orozco I.J., Peters P.J., and van der Bliek A.M. Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria. J. Biol. Chem. 279 (2004) 18792-18798
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18792-18798
-
-
Griparic, L.1
van der Wel, N.N.2
Orozco, I.J.3
Peters, P.J.4
van der Bliek, A.M.5
-
24
-
-
23044432581
-
The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses
-
Guo X., Macleod G.T., Wellington A., Hu F., Panchumarthi S., Schoenfield M., Marin L., Charlton M.P., Atwood H.L., and Zinsmaier K.E. The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses. Neuron 47 (2005) 379-393
-
(2005)
Neuron
, vol.47
, pp. 379-393
-
-
Guo, X.1
Macleod, G.T.2
Wellington, A.3
Hu, F.4
Panchumarthi, S.5
Schoenfield, M.6
Marin, L.7
Charlton, M.P.8
Atwood, H.L.9
Zinsmaier, K.E.10
-
25
-
-
77049308856
-
Aging: a theory based on free radical and radiation chemistry
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11 (1956) 298-300
-
(1956)
J. Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
26
-
-
0015319592
-
The biologic clock: the mitochondria?
-
Harman D. The biologic clock: the mitochondria?. J. Am. Geriatr. Soc. 20 (1972) 145-147
-
(1972)
J. Am. Geriatr. Soc.
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
27
-
-
0025836655
-
Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction
-
Hayashi J., Ohta S., Kikuchi A., Takemitsu M., Goto Y., and Nonaka I. Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction. Proc. Natl. Acad. Sci. USA 88 (1991) 10614-10618
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 10614-10618
-
-
Hayashi, J.1
Ohta, S.2
Kikuchi, A.3
Takemitsu, M.4
Goto, Y.5
Nonaka, I.6
-
28
-
-
0032547845
-
Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p
-
Hermann G.J., Thatcher J.W., Mills J.P., Hales K.G., Fuller M.T., Nunnari J., and Shaw J.M. Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p. J. Cell Biol. 143 (1998) 359-373
-
(1998)
J. Cell Biol.
, vol.143
, pp. 359-373
-
-
Hermann, G.J.1
Thatcher, J.W.2
Mills, J.P.3
Hales, K.G.4
Fuller, M.T.5
Nunnari, J.6
Shaw, J.M.7
-
29
-
-
0023883150
-
Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies
-
Holt I.J., Harding A.E., and Morgan-Hughes J.A. Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies. Nature 331 (1988) 717-719
-
(1988)
Nature
, vol.331
, pp. 717-719
-
-
Holt, I.J.1
Harding, A.E.2
Morgan-Hughes, J.A.3
-
30
-
-
3242705680
-
The functional organization of mitochondrial genomes in human cells
-
Iborra F.J., Kimura H., and Cook P.R. The functional organization of mitochondrial genomes in human cells. BMC Biol. 2 (2004) 9
-
(2004)
BMC Biol.
, vol.2
, pp. 9
-
-
Iborra, F.J.1
Kimura, H.2
Cook, P.R.3
-
31
-
-
25444471534
-
Dnm1 forms spirals that are structurally tailored to fit mitochondria
-
Ingerman E., Perkins E.M., Marino M., Mears J.A., McCaffery J.M., Hinshaw J.E., and Nunnari J. Dnm1 forms spirals that are structurally tailored to fit mitochondria. J. Cell Biol. 170 (2005) 1021-1027
-
(2005)
J. Cell Biol.
, vol.170
, pp. 1021-1027
-
-
Ingerman, E.1
Perkins, E.M.2
Marino, M.3
Mears, J.A.4
McCaffery, J.M.5
Hinshaw, J.E.6
Nunnari, J.7
-
32
-
-
0033772263
-
Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes
-
Inoue K., Nakada K., Ogura A., Isobe K., Goto Y., Nonaka I., and Hayashi J.I. Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes. Nat. Genet. 26 (2000) 176-181
-
(2000)
Nat. Genet.
, vol.26
, pp. 176-181
-
-
Inoue, K.1
Nakada, K.2
Ogura, A.3
Isobe, K.4
Goto, Y.5
Nonaka, I.6
Hayashi, J.I.7
-
33
-
-
13944278072
-
DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans
-
Jagasia R., Grote P., Westermann B., and Conradt B. DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans. Nature 433 (2005) 754-760
-
(2005)
Nature
, vol.433
, pp. 754-760
-
-
Jagasia, R.1
Grote, P.2
Westermann, B.3
Conradt, B.4
-
34
-
-
33644667634
-
Expression of the Opa1 mitochondrial protein in retinal ganglion cells: its downregulation causes aggregation of the mitochondrial network
-
Kamei S., Chen-Kuo-Chang M., Cazevieille C., Lenaers G., Olichon A., Belenguer P., Roussignol G., Renard N., Eybalin M., Michelin A., et al. Expression of the Opa1 mitochondrial protein in retinal ganglion cells: its downregulation causes aggregation of the mitochondrial network. Invest. Ophthalmol. Vis. Sci. 46 (2005) 4288-4294
-
(2005)
Invest. Ophthalmol. Vis. Sci.
, vol.46
, pp. 4288-4294
-
-
Kamei, S.1
Chen-Kuo-Chang, M.2
Cazevieille, C.3
Lenaers, G.4
Olichon, A.5
Belenguer, P.6
Roussignol, G.7
Renard, N.8
Eybalin, M.9
Michelin, A.10
-
35
-
-
33644772616
-
Generation of trans-mitochondrial mice carrying homoplasmic mtDNAs with a missense mutation in a structural gene using ES cells
-
Kasahara A., Ishikawa K., Yamaoka M., Ito M., Watanabe N., Akimoto M., Sato A., Nakada K., Endo H., Suda Y., et al. Generation of trans-mitochondrial mice carrying homoplasmic mtDNAs with a missense mutation in a structural gene using ES cells. Hum. Mol. Genet. 15 (2006) 871-881
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 871-881
-
-
Kasahara, A.1
Ishikawa, K.2
Yamaoka, M.3
Ito, M.4
Watanabe, N.5
Akimoto, M.6
Sato, A.7
Nakada, K.8
Endo, H.9
Suda, Y.10
-
36
-
-
15244364005
-
Mitochondrial DNA content is decreased in autosomal dominant optic atrophy
-
Kim J.Y., Hwang J.M., Ko H.S., Seong M.W., Park B.J., and Park S.S. Mitochondrial DNA content is decreased in autosomal dominant optic atrophy. Neurology 64 (2005) 966-972
-
(2005)
Neurology
, vol.64
, pp. 966-972
-
-
Kim, J.Y.1
Hwang, J.M.2
Ko, H.S.3
Seong, M.W.4
Park, B.J.5
Park, S.S.6
-
37
-
-
13944262937
-
Understanding the odd science of aging
-
Kirkwood T.B. Understanding the odd science of aging. Cell 120 (2005) 437-447
-
(2005)
Cell
, vol.120
, pp. 437-447
-
-
Kirkwood, T.B.1
-
38
-
-
3843075121
-
Structural basis of mitochondrial tethering by mitofusin complexes
-
Koshiba T., Detmer S.A., Kaiser J.T., Chen H., McCaffery J.M., and Chan D.C. Structural basis of mitochondrial tethering by mitofusin complexes. Science 305 (2004) 858-862
-
(2004)
Science
, vol.305
, pp. 858-862
-
-
Koshiba, T.1
Detmer, S.A.2
Kaiser, J.T.3
Chen, H.4
McCaffery, J.M.5
Chan, D.C.6
-
39
-
-
2442609784
-
Recombination of human mitochondrial DNA
-
Kraytsberg Y., Schwartz M., Brown T.A., Ebralidse K., Kunz W.S., Clayton D.A., Vissing J., and Khrapko K. Recombination of human mitochondrial DNA. Science 304 (2004) 981
-
(2004)
Science
, vol.304
, pp. 981
-
-
Kraytsberg, Y.1
Schwartz, M.2
Brown, T.A.3
Ebralidse, K.4
Kunz, W.S.5
Clayton, D.A.6
Vissing, J.7
Khrapko, K.8
-
40
-
-
33646351299
-
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
-
Kraytsberg Y., Kudryavtseva E., McKee A.C., Geula C., Kowall N.W., and Khrapko K. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat. Genet. 38 (2006) 518-520
-
(2006)
Nat. Genet.
, vol.38
, pp. 518-520
-
-
Kraytsberg, Y.1
Kudryavtseva, E.2
McKee, A.C.3
Geula, C.4
Kowall, N.W.5
Khrapko, K.6
-
41
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth G.C., Hiona A., Pugh T.D., Someya S., Panzer K., Wohlgemuth S.E., Hofer T., Seo A.Y., Sullivan R., Jobling W.A., et al. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309 (2005) 481-484
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
-
42
-
-
0033231549
-
C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane
-
Labrousse A.M., Zappaterra M.D., Rube D.A., and van der Bliek A.M. C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane. Mol. Cell 4 (1999) 815-826
-
(1999)
Mol. Cell
, vol.4
, pp. 815-826
-
-
Labrousse, A.M.1
Zappaterra, M.D.2
Rube, D.A.3
van der Bliek, A.M.4
-
43
-
-
16844369889
-
Nuclear and mitochondrial DNA repair: similar pathways?
-
Larsen N.B., Rasmussen M., and Rasmussen L.J. Nuclear and mitochondrial DNA repair: similar pathways?. Mitochondrion 5 (2005) 89-108
-
(2005)
Mitochondrion
, vol.5
, pp. 89-108
-
-
Larsen, N.B.1
Rasmussen, M.2
Rasmussen, L.J.3
-
44
-
-
0031930319
-
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
-
Larsson N.G., Wang J., Wilhelmsson H., Oldfors A., Rustin P., Lewandoski M., Barsh G.S., and Clayton D.A. Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat. Genet. 18 (1998) 231-236
-
(1998)
Nat. Genet.
, vol.18
, pp. 231-236
-
-
Larsson, N.G.1
Wang, J.2
Wilhelmsson, H.3
Oldfors, A.4
Rustin, P.5
Lewandoski, M.6
Barsh, G.S.7
Clayton, D.A.8
-
45
-
-
6344274848
-
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis
-
Lee Y.J., Jeong S.Y., Karbowski M., Smith C.L., and Youle R.J. Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis. Mol. Biol. Cell 15 (2004) 5001-5011
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 5001-5011
-
-
Lee, Y.J.1
Jeong, S.Y.2
Karbowski, M.3
Smith, C.L.4
Youle, R.J.5
-
46
-
-
0036906665
-
Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins
-
Legros F., Lombes A., Frachon P., and Rojo M. Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. Mol. Biol. Cell 13 (2002) 4343-4354
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 4343-4354
-
-
Legros, F.1
Lombes, A.2
Frachon, P.3
Rojo, M.4
-
47
-
-
3242884720
-
Organization and dynamics of human mitochondrial DNA
-
Legros F., Malka F., Frachon P., Lombes A., and Rojo M. Organization and dynamics of human mitochondrial DNA. J. Cell Sci. 117 (2004) 2653-2662
-
(2004)
J. Cell Sci.
, vol.117
, pp. 2653-2662
-
-
Legros, F.1
Malka, F.2
Frachon, P.3
Lombes, A.4
Rojo, M.5
-
48
-
-
10944269186
-
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
-
Li Z., Okamoto K., Hayashi Y., and Sheng M. The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell 119 (2004) 873-887
-
(2004)
Cell
, vol.119
, pp. 873-887
-
-
Li, Z.1
Okamoto, K.2
Hayashi, Y.3
Sheng, M.4
-
49
-
-
0024541837
-
Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
-
Linnane A.W., Marzuki S., Ozawa T., and Tanaka M. Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet 1 (1989) 642-645
-
(1989)
Lancet
, vol.1
, pp. 642-645
-
-
Linnane, A.W.1
Marzuki, S.2
Ozawa, T.3
Tanaka, M.4
-
50
-
-
9144238312
-
Deficit of in vivo mitochondrial ATP production in OPA1-related dominant optic atrophy
-
Lodi R., Tonon C., Valentino M.L., Iotti S., Clementi V., Malucelli E., Barboni P., Longanesi L., Schimpf S., Wissinger B., et al. Deficit of in vivo mitochondrial ATP production in OPA1-related dominant optic atrophy. Ann. Neurol. 56 (2004) 719-723
-
(2004)
Ann. Neurol.
, vol.56
, pp. 719-723
-
-
Lodi, R.1
Tonon, C.2
Valentino, M.L.3
Iotti, S.4
Clementi, V.5
Malucelli, E.6
Barboni, P.7
Longanesi, L.8
Schimpf, S.9
Wissinger, B.10
-
51
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
Lowell B.B., and Shulman G.I. Mitochondrial dysfunction and type 2 diabetes. Science 307 (2005) 384-387
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
-
52
-
-
0842285626
-
Mitochondrial diabetes: molecular mechanisms and clinical presentation
-
Maassen J.A., Hart L.M., Essen E., Heine R.J., Nijpels G., Tafrechi R., Raap A.K., Janssen G., and Lemkes H. Mitochondrial diabetes: molecular mechanisms and clinical presentation. Diabetes 53 (2004) S103-S109
-
(2004)
Diabetes
, vol.53
-
-
Maassen, J.A.1
Hart, L.M.2
Essen, E.3
Heine, R.J.4
Nijpels, G.5
Tafrechi, R.6
Raap, A.K.7
Janssen, G.8
Lemkes, H.9
-
53
-
-
0035856942
-
Mitochondrial function in normal and diabetic beta-cells
-
Maechler P., and Wollheim C.B. Mitochondrial function in normal and diabetic beta-cells. Nature 414 (2001) 807-812
-
(2001)
Nature
, vol.414
, pp. 807-812
-
-
Maechler, P.1
Wollheim, C.B.2
-
54
-
-
0037434879
-
Fusion of mitochondria in mammalian cells is dependent on the mitochondrial inner membrane potential and independent of microtubules or actin
-
Mattenberger Y., James D.I., and Martinou J.C. Fusion of mitochondria in mammalian cells is dependent on the mitochondrial inner membrane potential and independent of microtubules or actin. FEBS Lett. 538 (2003) 53-59
-
(2003)
FEBS Lett.
, vol.538
, pp. 53-59
-
-
Mattenberger, Y.1
James, D.I.2
Martinou, J.C.3
-
55
-
-
0033595684
-
Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication
-
Michikawa Y., Mazzucchelli F., Bresolin N., Scarlato G., and Attardi G. Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication. Science 286 (1999) 774-779
-
(1999)
Science
, vol.286
, pp. 774-779
-
-
Michikawa, Y.1
Mazzucchelli, F.2
Bresolin, N.3
Scarlato, G.4
Attardi, G.5
-
56
-
-
0033981319
-
Apoptosis in mitochondrial encephalomyopathies with mitochondrial DNA mutations: a potential pathogenic mechanism
-
Mirabella M., Di Giovanni S., Silvestri G., Tonali P., and Servidei S. Apoptosis in mitochondrial encephalomyopathies with mitochondrial DNA mutations: a potential pathogenic mechanism. Brain 123 (2000) 93-104
-
(2000)
Brain
, vol.123
, pp. 93-104
-
-
Mirabella, M.1
Di Giovanni, S.2
Silvestri, G.3
Tonali, P.4
Servidei, S.5
-
57
-
-
0028861992
-
Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons
-
Morris R.L., and Hollenbeck P.J. Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons. J. Cell Biol. 131 (1995) 1315-1326
-
(1995)
J. Cell Biol.
, vol.131
, pp. 1315-1326
-
-
Morris, R.L.1
Hollenbeck, P.J.2
-
58
-
-
0034676096
-
Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p
-
Mozdy A.D., McCaffery J.M., and Shaw J.M. Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p. J. Cell Biol. 151 (2000) 367-380
-
(2000)
J. Cell Biol.
, vol.151
, pp. 367-380
-
-
Mozdy, A.D.1
McCaffery, J.M.2
Shaw, J.M.3
-
59
-
-
0034881326
-
Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA
-
Nakada K., Inoue K., Ono T., Isobe K., Ogura A., Goto Y.I., Nonaka I., and Hayashi J.I. Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA. Nat. Med. 7 (2001) 934-940
-
(2001)
Nat. Med.
, vol.7
, pp. 934-940
-
-
Nakada, K.1
Inoue, K.2
Ono, T.3
Isobe, K.4
Ogura, A.5
Goto, Y.I.6
Nonaka, I.7
Hayashi, J.I.8
-
60
-
-
25444514731
-
Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease
-
Niemann A., Ruegg M., La Padula V., Schenone A., and Suter U. Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease. J. Cell Biol. 170 (2005) 1067-1078
-
(2005)
J. Cell Biol.
, vol.170
, pp. 1067-1078
-
-
Niemann, A.1
Ruegg, M.2
La Padula, V.3
Schenone, A.4
Suter, U.5
-
61
-
-
27544466847
-
Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes
-
Okamoto K., and Shaw J.M. Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes. Annu. Rev. Genet. 39 (2005) 503-536
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 503-536
-
-
Okamoto, K.1
Shaw, J.M.2
-
62
-
-
0037424239
-
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
-
Olichon A., Baricault L., Gas N., Guillou E., Valette A., Belenguer P., and Lenaers G. Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J. Biol. Chem. 278 (2003) 7743-7746
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7743-7746
-
-
Olichon, A.1
Baricault, L.2
Gas, N.3
Guillou, E.4
Valette, A.5
Belenguer, P.6
Lenaers, G.7
-
63
-
-
0034938453
-
Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria
-
Ono T., Isobe K., Nakada K., and Hayashi J.I. Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria. Nat. Genet. 28 (2001) 272-275
-
(2001)
Nat. Genet.
, vol.28
, pp. 272-275
-
-
Ono, T.1
Isobe, K.2
Nakada, K.3
Hayashi, J.I.4
-
64
-
-
7544246760
-
Dominant optic atrophy, sensorineural hearing loss, ptosis, and ophthalmoplegia: a syndrome caused by a missense mutation in OPA1
-
Payne M., Yang Z., Katz B.J., Warner J.E., Weight C.J., Zhao Y., Pearson E.D., Treft R.L., Hillman T., Kennedy R.J., et al. Dominant optic atrophy, sensorineural hearing loss, ptosis, and ophthalmoplegia: a syndrome caused by a missense mutation in OPA1. Am. J. Ophthalmol. 138 (2004) 749-755
-
(2004)
Am. J. Ophthalmol.
, vol.138
, pp. 749-755
-
-
Payne, M.1
Yang, Z.2
Katz, B.J.3
Warner, J.E.4
Weight, C.J.5
Zhao, Y.6
Pearson, E.D.7
Treft, R.L.8
Hillman, T.9
Kennedy, R.J.10
-
65
-
-
16844377411
-
Mitochondrial fusion and fission in the control of apoptosis
-
Perfettini J.L., Roumier T., and Kroemer G. Mitochondrial fusion and fission in the control of apoptosis. Trends Cell Biol. 15 (2005) 179-183
-
(2005)
Trends Cell Biol.
, vol.15
, pp. 179-183
-
-
Perfettini, J.L.1
Roumier, T.2
Kroemer, G.3
-
66
-
-
0742288598
-
The dynamin superfamily: universal membrane tubulation and fission molecules?
-
Praefcke G.J., and McMahon H.T. The dynamin superfamily: universal membrane tubulation and fission molecules?. Nat. Rev. Mol. Cell Biol. 5 (2004) 133-147
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 133-147
-
-
Praefcke, G.J.1
McMahon, H.T.2
-
67
-
-
0023811053
-
Normal oxidative damage to mitochondrial and nuclear DNA is extensive
-
Richter C., Park J.W., and Ames B.N. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc. Natl. Acad. Sci. USA 85 (1988) 6465-6467
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 6465-6467
-
-
Richter, C.1
Park, J.W.2
Ames, B.N.3
-
68
-
-
21144434217
-
Extension of murine life span by overexpression of catalase targeted to mitochondria
-
Schriner S.E., Linford N.J., Martin G.M., Treuting P., Ogburn C.E., Emond M., Coskun P.E., Ladiges W., Wolf N., Van Remmen H., et al. Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 308 (2005) 1909-1911
-
(2005)
Science
, vol.308
, pp. 1909-1911
-
-
Schriner, S.E.1
Linford, N.J.2
Martin, G.M.3
Treuting, P.4
Ogburn, C.E.5
Emond, M.6
Coskun, P.E.7
Ladiges, W.8
Wolf, N.9
Van Remmen, H.10
-
69
-
-
0033571410
-
Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape
-
Sesaki H., and Jensen R.E. Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape. J. Cell Biol. 147 (1999) 699-706
-
(1999)
J. Cell Biol.
, vol.147
, pp. 699-706
-
-
Sesaki, H.1
Jensen, R.E.2
-
70
-
-
0033646646
-
Mitochondrial DNA segregation in the developing embryo
-
Shoubridge E.A. Mitochondrial DNA segregation in the developing embryo. Hum. Reprod. 15 Suppl 2 (2000) 229-234
-
(2000)
Hum. Reprod.
, vol.15
, Issue.SUPPL. 2
, pp. 229-234
-
-
Shoubridge, E.A.1
-
71
-
-
0033762782
-
Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes
-
Silva J.P., Kohler M., Graff C., Oldfors A., Magnuson M.A., Berggren P.O., and Larsson N.G. Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes. Nat. Genet. 26 (2000) 336-340
-
(2000)
Nat. Genet.
, vol.26
, pp. 336-340
-
-
Silva, J.P.1
Kohler, M.2
Graff, C.3
Oldfors, A.4
Magnuson, M.A.5
Berggren, P.O.6
Larsson, N.G.7
-
72
-
-
0035146891
-
Mitochondrial filaments and clusters as intracellular power-transmitting cables
-
Skulachev V.P. Mitochondrial filaments and clusters as intracellular power-transmitting cables. Trends Biochem. Sci. 26 (2001) 23-29
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 23-29
-
-
Skulachev, V.P.1
-
73
-
-
0034687797
-
Maternal germ-line transmission of mutant mtDNAs from embryonic stem cell-derived chimeric mice
-
Sligh J.E., Levy S.E., Waymire K.G., Allard P., Dillehay D.L., Nusinowitz S., Heckenlively J.R., MacGregor G.R., and Wallace D.C. Maternal germ-line transmission of mutant mtDNAs from embryonic stem cell-derived chimeric mice. Proc. Natl. Acad. Sci. USA 97 (2000) 14461-14466
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14461-14466
-
-
Sligh, J.E.1
Levy, S.E.2
Waymire, K.G.3
Allard, P.4
Dillehay, D.L.5
Nusinowitz, S.6
Heckenlively, J.R.7
MacGregor, G.R.8
Wallace, D.C.9
-
74
-
-
0035166814
-
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells
-
Smirnova E., Griparic L., Shurland D.L., and van der Bliek A.M. Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol. Biol. Cell 12 (2001) 2245-2256
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2245-2256
-
-
Smirnova, E.1
Griparic, L.2
Shurland, D.L.3
van der Bliek, A.M.4
-
75
-
-
0037137704
-
Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein
-
Stowers R.S., Megeath L.J., Gorska-Andrzejak J., Meinertzhagen I.A., and Schwarz T.L. Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein. Neuron 36 (2002) 1063-1077
-
(2002)
Neuron
, vol.36
, pp. 1063-1077
-
-
Stowers, R.S.1
Megeath, L.J.2
Gorska-Andrzejak, J.3
Meinertzhagen, I.A.4
Schwarz, T.L.5
-
76
-
-
10644296253
-
Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis
-
Sugioka R., Shimizu S., and Tsujimoto Y. Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis. J. Biol. Chem. 279 (2004) 52726-52734
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 52726-52734
-
-
Sugioka, R.1
Shimizu, S.2
Tsujimoto, Y.3
-
77
-
-
0036322806
-
The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission
-
Tieu Q., Okreglak V., Naylor K., and Nunnari J. The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission. J. Cell Biol. 158 (2002) 445-452
-
(2002)
J. Cell Biol.
, vol.158
, pp. 445-452
-
-
Tieu, Q.1
Okreglak, V.2
Naylor, K.3
Nunnari, J.4
-
78
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic A., Wredenberg A., Falkenberg M., Spelbrink J.N., Rovio A.T., Bruder C.E., Bohlooly Y.M., Gidlof S., Oldfors A., Wibom R., et al. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429 (2004) 417-423
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlof, S.8
Oldfors, A.9
Wibom, R.10
-
79
-
-
0024580556
-
Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in ageing
-
Trounce I., Byrne E., and Marzuki S. Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in ageing. Lancet 1 (1989) 637-639
-
(1989)
Lancet
, vol.1
, pp. 637-639
-
-
Trounce, I.1
Byrne, E.2
Marzuki, S.3
-
80
-
-
29144486726
-
Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice
-
Tyynismaa H., Mjosund K.P., Wanrooij S., Lappalainen I., Ylikallio E., Jalanko A., Spelbrink J.N., Paetau A., and Suomalainen A. Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice. Proc. Natl. Acad. Sci. USA 102 (2005) 17687-17692
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 17687-17692
-
-
Tyynismaa, H.1
Mjosund, K.P.2
Wanrooij, S.3
Lappalainen, I.4
Ylikallio, E.5
Jalanko, A.6
Spelbrink, J.N.7
Paetau, A.8
Suomalainen, A.9
-
81
-
-
23044506102
-
Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions
-
Verstreken P., Ly C.V., Venken K.J., Koh T.W., Zhou Y., and Bellen H.J. Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. Neuron 47 (2005) 365-378
-
(2005)
Neuron
, vol.47
, pp. 365-378
-
-
Verstreken, P.1
Ly, C.V.2
Venken, K.J.3
Koh, T.W.4
Zhou, Y.5
Bellen, H.J.6
-
82
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
-
Wallace D.C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine. Annu. Rev. Genet. 39 (2005) 359-407
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
83
-
-
0024242545
-
Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy
-
Wallace D.C., Singh G., Lott M.T., Hodge J.A., Schurr T.G., Lezza A.M., Elsas II L.J., and Nikoskelainen E.K. Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. Science 242 (1988) 1427-1430
-
(1988)
Science
, vol.242
, pp. 1427-1430
-
-
Wallace, D.C.1
Singh, G.2
Lott, M.T.3
Hodge, J.A.4
Schurr, T.G.5
Lezza, A.M.6
Elsas II, L.J.7
Nikoskelainen, E.K.8
-
84
-
-
8444228909
-
A cluster of metabolic defects caused by mutation in a mitochondrial tRNA
-
Wilson F.H., Hariri A., Farhi A., Zhao H., Petersen K.F., Toka H.R., Nelson-Williams C., Raja K.M., Kashgarian M., Shulman G.I., et al. A cluster of metabolic defects caused by mutation in a mitochondrial tRNA. Science 306 (2004) 1190-1194
-
(2004)
Science
, vol.306
, pp. 1190-1194
-
-
Wilson, F.H.1
Hariri, A.2
Farhi, A.3
Zhao, H.4
Petersen, K.F.5
Toka, H.R.6
Nelson-Williams, C.7
Raja, K.M.8
Kashgarian, M.9
Shulman, G.I.10
-
85
-
-
0028348251
-
Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles
-
Yoneda M., Miyatake T., and Attardi G. Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles. Mol. Cell. Biol. 14 (1994) 2699-2712
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2699-2712
-
-
Yoneda, M.1
Miyatake, T.2
Attardi, G.3
-
87
-
-
28544441744
-
Emerging pathways for hereditary axonopathies
-
Zuchner S., and Vance J.M. Emerging pathways for hereditary axonopathies. J. Mol. Med. 83 (2005) 935-943
-
(2005)
J. Mol. Med.
, vol.83
, pp. 935-943
-
-
Zuchner, S.1
Vance, J.M.2
-
88
-
-
2442589922
-
Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A
-
Zuchner S., Mersiyanova I.V., Muglia M., Bissar-Tadmouri N., Rochelle J., Dadali E.L., Zappia M., Nelis E., Patitucci A., Senderek J., et al. Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A. Nat. Genet. 36 (2004) 449-451
-
(2004)
Nat. Genet.
, vol.36
, pp. 449-451
-
-
Zuchner, S.1
Mersiyanova, I.V.2
Muglia, M.3
Bissar-Tadmouri, N.4
Rochelle, J.5
Dadali, E.L.6
Zappia, M.7
Nelis, E.8
Patitucci, A.9
Senderek, J.10
-
89
-
-
32044474896
-
Axonal neuropathy with optic atrophy is caused by mutations in mitofusin 2
-
Zuchner S., De Jonghe P., Jordanova A., Claeys K.G., Guergueltcheva V., Cherninkova S., Hamilton S.R., Van Stavern G., Krajewski K.M., Stajich J., et al. Axonal neuropathy with optic atrophy is caused by mutations in mitofusin 2. Ann. Neurol. 59 (2006) 276-281
-
(2006)
Ann. Neurol.
, vol.59
, pp. 276-281
-
-
Zuchner, S.1
De Jonghe, P.2
Jordanova, A.3
Claeys, K.G.4
Guergueltcheva, V.5
Cherninkova, S.6
Hamilton, S.R.7
Van Stavern, G.8
Krajewski, K.M.9
Stajich, J.10
|