p53- and Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa

Science

Volumn 302, Issue 5647, 2003, Pages 1036-1038

  Villunger, Andreas ^a   Michalak, Ewa M ^a   Coultas, Leigh ^a   Müllauer, Franziska ^b   Böck, Günther ^b   Ausserlechner, Michael J ^b   Adams, Jerry M ^a   Strasser, Andreas ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; DRUG PRODUCTS; GENES;

APOPTOTIC RESPONSES;

PROTEINS;

BH3 PROTEIN; CYTOKINE; DNA; DRUG; ETOPOSIDE; GLUCOCORTICOID; PHORBOL ESTER; PROTEIN NOXA; PROTEIN P53; PROTEIN PUMA; STAUROSPORINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

DAMAGE; DNA; PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; EMBRYO; FIBROBLAST; GENE CONTROL; GENE FUNCTION; GENE INDUCTION; GENETIC CODE; LYMPHOCYTE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FAMILY; PROTEIN FUNCTION; SOUTHERN BLOTTING; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; B-LYMPHOCYTES; CELL TRANSFORMATION, VIRAL; CYTOKINES; DEXAMETHASONE; DNA DAMAGE; ETOPOSIDE; FIBROBLASTS; GAMMA RAYS; GENE TARGETING; IONOMYCIN; LYMPHOCYTES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; T-LYMPHOCYTES; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0242410719     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1090072     Document Type: Article

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