-
1
-
-
0032531924
-
Parkinson's disease. Second of two parts
-
Lang, A.E., and Lozano, A.M. 1998. Parkinson's disease. Second of two parts. N. Engl. J. Med. 339:1130-1143.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1130-1143
-
-
Lang, A.E.1
Lozano, A.M.2
-
2
-
-
0032497504
-
Parkinson's disease. First of two parts
-
Lang, A.E., and Lozano, A.M. 1998. Parkinson's disease. First of two parts. N. Engl. J. Med. 339:1044-1053.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1044-1053
-
-
Lang, A.E.1
Lozano, A.M.2
-
3
-
-
0029981526
-
Neuropathology of Parkinson's disease
-
Forno, L.S. 1996. Neuropathology of Parkinson's disease. J. Neuropathol. Exp. Neurol. 55:259-272.
-
(1996)
J. Neuropathol. Exp. Neurol.
, vol.55
, pp. 259-272
-
-
Forno, L.S.1
-
4
-
-
0034798193
-
Genetics of Parkinson's disease
-
Gasser, T. 2001. Genetics of Parkinson's disease. J. Neurol. 248:833-840.
-
(2001)
J. Neurol.
, vol.248
, pp. 833-840
-
-
Gasser, T.1
-
5
-
-
0032461761
-
Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg
-
Roses, A.D. 1998. Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg. Ann. NY Acad. Sci. 855:738-743.
-
(1998)
Ann. NY Acad. Sci.
, vol.855
, pp. 738-743
-
-
Roses, A.D.1
-
6
-
-
0037130450
-
Animal models of PD: Pieces of the same puzzle?
-
Dawson, T., Mandir, A., and Lee, M. 2002. Animal models of PD: pieces of the same puzzle? Neuron. 35:219-222.
-
(2002)
Neuron
, vol.35
, pp. 219-222
-
-
Dawson, T.1
Mandir, A.2
Lee, M.3
-
7
-
-
0035959931
-
Parkin and the molecular pathways of Parkinson's disease
-
Giasson, B.I., and Lee, V.M. 2001. Parkin and the molecular pathways of Parkinson's disease. Neuron. 31:885-888.
-
(2001)
Neuron
, vol.31
, pp. 885-888
-
-
Giasson, B.I.1
Lee, V.M.2
-
8
-
-
10544234193
-
Mapping of a gene for Parkinson's disease to chromosome 4q21-q23
-
Polymeropoulos, M.H., et al. 1996. Mapping of a gene for Parkinson's disease to chromosome 4q21-q23. Science. 274:1197-1199.
-
(1996)
Science
, vol.274
, pp. 1197-1199
-
-
Polymeropoulos, M.H.1
-
9
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos, M.H., et al. 1997. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science. 276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
-
10
-
-
0032499264
-
Mutations in the Parkin gene cause autosomal recessive juvenile Parkinsonism
-
Kitada, T., et al. 1998. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature. 392:605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
-
11
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
doi:10.1126/ science.1077209
-
Bonifati, V., et al. 2002. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science. doi:10.1126/ science.1077209.
-
(2002)
Science
-
-
Bonifati, V.1
-
12
-
-
0037131567
-
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility
-
Liu, Y., Fallon, L., Lashuel, H.A., Liu, Z., and Lansbury, P.T., Jr. 2002. The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Cell. 111:209-218.
-
(2002)
Cell
, vol.111
, pp. 209-218
-
-
Liu, Y.1
Fallon, L.2
Lashuel, H.A.3
Liu, Z.4
Lansbury P.T., Jr.5
-
13
-
-
0031951197
-
A susceptibility locus for Parkinson's disease maps to chromosome 2p13
-
Gasser, T., et at. 1998. A susceptibility locus for Parkinson's disease maps to chromosome 2p13. Nat. Genet. 18:262-265.
-
(1998)
Nat. Genet.
, vol.18
, pp. 262-265
-
-
Gasser, T.1
-
14
-
-
0032911910
-
A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor
-
Farrer, M., et al. 1999. A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor. Hum. Mol. Genet. 8:81-85.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 81-85
-
-
Farrer, M.1
-
15
-
-
15144345616
-
Hereditary form of Parkinsonism - Dementia
-
Muenter, M.D., et al. 1998. Hereditary form of parkinsonism - dementia. Ann. Neurol. 43:768-781.
-
(1998)
Ann. Neurol.
, vol.43
, pp. 768-781
-
-
Muenter, M.D.1
-
16
-
-
0035068574
-
Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36
-
Valence, E.M., et al. 2001. Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36. Am. J. Hum. Genet. 68:895-900.
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 895-900
-
-
Valence, E.M.1
-
17
-
-
0034892917
-
Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36
-
van Duijn, C.M., et al. 2001. Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36. Am. J. Hum. Genet. 69:629-634.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 629-634
-
-
Van Duijn, C.M.1
-
18
-
-
0036196860
-
A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13. 1
-
Funayama, M., et al. 2002. A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13. 1. Ann. Neurol. 51:296-301.
-
(2002)
Ann. Neurol.
, vol.51
, pp. 296-301
-
-
Funayama, M.1
-
19
-
-
0034796326
-
Ku£or-Rakeb syndrome, pallido-pyramidal degeneration with supranuclear upgaze paresis and dementia, maps to 1p36
-
Hampshire, D.J., et al. 2001. Ku£or-Rakeb syndrome, pallido-pyramidal degeneration with supranuclear upgaze paresis and dementia, maps to 1p36. J. Med. Genet. 38:680-682.
-
(2001)
J. Med. Genet.
, vol.38
, pp. 680-682
-
-
Hampshire, D.J.1
-
20
-
-
0034649710
-
Familial aggregation of Parkinson's disease in Iceland
-
Sveinbjornsdottir, S., et al. 200C. Familial aggregation of Parkinson's disease in Iceland. N. Engl. J. Med. 343:1765-1770.
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 1765-1770
-
-
Sveinbjornsdottir, S.1
-
21
-
-
0036830525
-
A susceptibility gene for late-onset idiopathic Parkinson's disease
-
Hicks, A.A., et al. 2002. A susceptibility gene for late-onset idiopathic Parkinson's disease. Ann. Neurol. 52:549-555.
-
(2002)
Ann. Neurol.
, vol.52
, pp. 549-555
-
-
Hicks, A.A.1
-
22
-
-
0035860983
-
Complete genomic screen in Parkinson disease: Evidence for multiple genes
-
Scott, W.K., et al. 2001. Complete genomic screen in Parkinson disease: evidence for multiple genes. JAMA. 286:2239-2244.
-
(2001)
JAMA
, vol.286
, pp. 2239-2244
-
-
Scott, W.K.1
-
23
-
-
0035861048
-
Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease
-
Martin, E.R., et al. 2001. Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease. JAMA. 286:2245-2250.
-
(2001)
JAMA
, vol.286
, pp. 2245-2250
-
-
Martin, E.R.1
-
24
-
-
0034760406
-
Case-control study of the extended tau gene haplotype in Parkinson's disease
-
Maraganore, D.M., et al. 2001. Case-control study of the extended tau gene haplotype in Parkinson's disease. Ann. Neurol. 50:658-661.
-
(2001)
Ann. Neurol.
, vol.50
, pp. 658-661
-
-
Maraganore, D.M.1
-
25
-
-
0035353746
-
The tau A0 allele in Parkinson's disease
-
Golbe, L.I., et al. 2001. The tau A0 allele in Parkinson's disease. Mov. Disord. 16:442-447.
-
(2001)
Mov. Disord.
, vol.16
, pp. 442-447
-
-
Golbe, L.I.1
-
26
-
-
0035134195
-
Familial atypical progressive supranuclear palsy associated with homozigosity for the delN296 mutation in the tau gene
-
Pastor, P., et al. 2001. Familial atypical progressive supranuclear palsy associated with homozigosity for the delN296 mutation in the tau gene. Ann. Neurol. 49:263-267.
-
(2001)
Ann. Neurol.
, vol.49
, pp. 263-267
-
-
Pastor, P.1
-
27
-
-
0032543684
-
Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
-
Hutton, M., et al. 1998. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17. Nature. 393:702-705.
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
-
28
-
-
0035949797
-
Genome-wide scan for Parkinson's disease: The GenePD Study
-
DeStefano, A.L., et al. 2001. Genome-wide scan for Parkinson's disease: the GenePD Study. Neurology. 57:1124-1126.
-
(2001)
Neurology
, vol.57
, pp. 1124-1126
-
-
DeStefano, A.L.1
-
29
-
-
18344393780
-
Age at onset in two common neurodegenerative diseases is genetically controlled
-
Li, Y.J., et al. 2002. Age at onset in two common neurodegenerative diseases is genetically controlled. Am. J. Hum. Genet. 70:985-993.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 985-993
-
-
Li, Y.J.1
-
30
-
-
0033608187
-
Parkinson disease in twins: An etiologic study
-
Tanner, C.M., et al. 1999. Parkinson disease in twins: an etiologic study. JAMA. 281:341-346.
-
(1999)
JAMA
, vol.281
, pp. 341-346
-
-
Tanner, C.M.1
-
31
-
-
0033022357
-
Mutated alpha-synuclein gene in two Greek kindreds with familial PD: Incomplete penetrance?
-
Papadimitriou, A., et al. 1999. Mutated alpha-synuclein gene in two Greek kindreds with familial PD: incomplete penetrance? Neurology. 52:651-654.
-
(1999)
Neurology
, vol.52
, pp. 651-654
-
-
Papadimitriou, A.1
-
32
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger, R., et al. 1998. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat. Genet. 18:106-108.
-
(1998)
Nat. Genet.
, vol.18
, pp. 106-108
-
-
Kruger, R.1
-
33
-
-
0035880458
-
Alpha-synuclein gene haplotypes are associated with Parkinson's disease
-
Farrer, M., et al. 2001. alpha-Synuclein gene haplotypes are associated with Parkinson's disease. Hum. Mol. Genet. 10:1847-1851.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1847-1851
-
-
Farrer, M.1
-
34
-
-
0032102455
-
The synucleins: A family of proteins involved in synaptic function, plasticity, neurodegeneration and disease
-
Clayton, D.F., and George, J.M. 1998. The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease. Trends Neurosci. 21:249-254.
-
(1998)
Trends Neurosci.
, vol.21
, pp. 249-254
-
-
Clayton, D.F.1
George, J.M.2
-
35
-
-
0001405187
-
Synucleinopathies: A pathological and molecular review
-
Murray, I.V.J., Lee, V.M., and Trojanowski, J.Q. 2001. Synucleinopathies: a pathological and molecular review. Clinical Neuroscience Research. 1:445-455.
-
(2001)
Clinical Neuroscience Research
, vol.1
, pp. 445-455
-
-
Murray, I.V.J.1
Lee, V.M.2
Trojanowski, J.Q.3
-
36
-
-
0034077041
-
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich, A., et al. 2000. Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron. 25:239-252.
-
(2000)
Neuron
, vol.25
, pp. 239-252
-
-
Abeliovich, A.1
-
37
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in alpha-synuclein mice: Implications for neurodegenerative disorders
-
Masliah, E., er al. 2000. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. Science. 287:1265-1269.
-
(2000)
Science
, vol.287
, pp. 1265-1269
-
-
Masliah, E.1
-
38
-
-
0037118259
-
Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-synuclein
-
Giasson, B.I., et al. 2002. Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-synuclein. Neuron. 34:521-533.
-
(2002)
Neuron
, vol.34
, pp. 521-533
-
-
Giasson, B.I.1
-
39
-
-
0000905836
-
Advances in genetic models of Parkinson's Disease
-
Lee, M.K., and Price, D.L. 2001. Advances in genetic models of Parkinson's Disease. Clinical Neuroscience Research. 1:456-466.
-
(2001)
Clinical Neuroscience Research
, vol.1
, pp. 456-466
-
-
Lee, M.K.1
Price, D.L.2
-
40
-
-
0037173006
-
Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 right-arrow Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice
-
Lee, M.K., et al. 2002. Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 right-arrow Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice. Proc. Natl. Acad. Sci. USA. 99:8968-8973.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8968-8973
-
-
Lee, M.K.1
-
41
-
-
0034280435
-
Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha-synuclein in human and transgenic mouse brain
-
Kahle, P.J., et al. 2000. Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha-synuclein in human and transgenic mouse brain. J. Neurosci. 20:6365-6373.
-
(2000)
J. Neurosci.
, vol.20
, pp. 6365-6373
-
-
Kahle, P.J.1
-
42
-
-
0034979314
-
Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter
-
Matsuoka, Y., et al. 2001. Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter. Neurobiol. Dis. 8:535-539.
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 535-539
-
-
Matsuoka, Y.1
-
43
-
-
0036245056
-
Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice
-
Richfield, E,K., et al. 2002. Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice. Exp. Neurol. 175:35-48.
-
(2002)
Exp. Neurol.
, vol.175
, pp. 35-48
-
-
Richfield, E.1
-
44
-
-
0034663176
-
Neuropathology in mice expressing human alpha-synuclein
-
van der Putten, H., et al. 2000. Neuropathology in mice expressing human alpha-synuclein. J. Neurosci. 20:6021-6029.
-
(2000)
J. Neurosci.
, vol.20
, pp. 6021-6029
-
-
Van der Putten, H.1
-
45
-
-
0035950270
-
β-synuclein inhibits α-synuclein aggregation: A possible role as an anti-parkinsonian factor
-
Hashimoto, M., Rockenstein, E., Mante, M., Mallory, M., and Masliah, E. 2001. β-Synuclein inhibits α-synuclein aggregation: a possible role as an anti-parkinsonian factor. Neuron. 32:213-223.
-
(2001)
Neuron
, vol.32
, pp. 213-223
-
-
Hashimoto, M.1
Rockenstein, E.2
Mante, M.3
Mallory, M.4
Masliah, E.5
-
46
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany, M.B., and Bender, W.W. 2000. A Drosophila model of Parkinson's disease. Nature. 404:394-398.
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
47
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
-
Auluck, P.K., Chan, H.Y.E., Trojanowski, J.Q., Lee, V.M., and Bonini, N.M. 2001. Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science. 295:865-868.
-
(2001)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.E.2
Trojanowski, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
48
-
-
0035870881
-
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
-
Tanaka, Y., et al. 2001. Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Hum. Mol. Genet. 10:919-926.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 919-926
-
-
Tanaka, Y.1
-
49
-
-
0035834360
-
Kinetic stabilization of the alpha-synuclein prorofibril by a dopamine-alpha-synuclein adduct
-
Conway, K.A., Rochet, J.C., Bieganski, R.M., and Lansbury, P.T., Jr. 2001. Kinetic stabilization of the alpha-synuclein prorofibril by a dopamine-alpha-synuclein adduct. Science. 294:1346-1349.
-
(2001)
Science
, vol.294
, pp. 1346-1349
-
-
Conway, K.A.1
Rochet, J.C.2
Bieganski, R.M.3
Lansbury P.T., Jr.4
-
50
-
-
0036278335
-
Dopamine-dependent neurotoxicity of alpha-synuclein: A mechanism for selective neurodegeneration in Parkinson disease
-
Xu, J., et al. 2002. Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease. Nat. Med. 8:600-606.
-
(2002)
Nat. Med.
, vol.8
, pp. 600-606
-
-
Xu, J.1
-
51
-
-
16944362288
-
Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2-27
-
Matsumine, H., et al. 1997. Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2-27. Am. J. Hum. Genet. 60:588-596.
-
(1997)
Am. J. Hum. Genet.
, vol.60
, pp. 588-596
-
-
Matsumine, H.1
-
52
-
-
0012641135
-
Parkin: Clinical aspects and neurobiology
-
Zhang, Y., Dawson, V.L., and Dawson, T.M. 2001. Parkin: clinical aspects and neurobiology. Clinical Neuroscience Research. 1:467-482.
-
(2001)
Clinical Neuroscience Research
, vol.1
, pp. 467-482
-
-
Zhang, Y.1
Dawson, V.L.2
Dawson, T.M.3
-
53
-
-
0342368772
-
Association between early-onset Parkinson's disease and mutations in the parkin gene
-
French Parkinson's Disease Genetics Study Group
-
Lucking, C.B., et al. 2000. Association between early-onset Parkinson's disease and mutations in the parkin gene. French Parkinson's Disease Genetics Study Group. N. Engl. J. Med. 342:1560-1567.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1560-1567
-
-
Lucking, C.B.1
-
54
-
-
0034646514
-
New animal models for Parkinson's disease
-
Dawson, T.M. 2000. New animal models for Parkinson's disease. Cell. 101:115-118.
-
(2000)
Cell
, vol.101
, pp. 115-118
-
-
Dawson, T.M.1
-
55
-
-
0034700158
-
Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
-
Zhang, Y., et al. 2000. Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc. Natl. Acad. Sci. USA. 97:13354-13359.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13354-13359
-
-
Zhang, Y.1
-
56
-
-
2942618660
-
The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders
-
Chung, K.K., Dawson, V.L., and Dawson, T.M. 2001. The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders. Trends Neurosci. 24(Suppl.):S7-S14.
-
(2001)
Trends Neurosci.
, vol.24
, Issue.SUPPL.
-
-
Chung, K.K.1
Dawson, V.L.2
Dawson, T.M.3
-
57
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura, H., et al. 2000. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat. Genet. 25:302-305.
-
(2000)
Nat. Genet.
, vol.25
, pp. 302-305
-
-
Shimura, H.1
-
58
-
-
0034680913
-
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
-
Imai, Y., Soda, M., and Takahashi, R. 2000. Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J. Biol. Chem. 275:35661-35664.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35661-35664
-
-
Imai, Y.1
Soda, M.2
Takahashi, R.3
-
59
-
-
0033363646
-
The septin CDCrel-1 binds syntaxin and inhibits exocytosis
-
Beites, C.L., Xie, H., Bowser, R., and Trimble, W.S. 1999. The septin CDCrel-1 binds syntaxin and inhibits exocytosis. Nat. Neurosci. 2:434-439.
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 434-439
-
-
Beites, C.L.1
Xie, H.2
Bowser, R.3
Trimble, W.S.4
-
60
-
-
0034776095
-
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease
-
Chung, K.K., et al. 2001. Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat. Med. 7:1144-1150.
-
(2001)
Nat. Med.
, vol.7
, pp. 1144-1150
-
-
Chung, K.K.1
-
61
-
-
0032952414
-
Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions
-
Engelender, S., et al. 1999. Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nat. Genet. 22:110-114.
-
(1999)
Nat. Genet.
, vol.22
, pp. 110-114
-
-
Engelender, S.1
-
62
-
-
0034085796
-
Synphilin-1 is present in Lewy bodies in Parkinson's disease
-
Wakabayashi, K., et al. 2000. Synphilin-1 is present in Lewy bodies in Parkinson's disease. Ann. Neurol. 47:521-523.
-
(2000)
Ann. Neurol.
, vol.47
, pp. 521-523
-
-
Wakabayashi, K.1
-
63
-
-
0034848395
-
Lewy bodies and parkinsonism in families with parkin mutations
-
Farrer, M., et al. 2001. Lewy bodies and parkinsonism in families with parkin mutations. Ann. Neurol. 50:293-300.
-
(2001)
Ann. Neurol.
, vol.50
, pp. 293-300
-
-
Farrer, M.1
-
64
-
-
0035854437
-
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease
-
Shimura, H., et al. 2001. Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science. 293:263-269.
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
-
65
-
-
0035967883
-
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
-
Imai, Y., et al. 2001. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell. 105:891-902.
-
(2001)
Cell
, vol.105
, pp. 891-902
-
-
Imai, Y.1
-
66
-
-
0035692636
-
DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin
-
Mitsumoto, A., and Nakagawa, Y. 2001. DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin. Free Radic. Res. 35:885-893.
-
(2001)
Free Radic. Res.
, vol.35
, pp. 885-893
-
-
Mitsumoto, A.1
Nakagawa, Y.2
-
67
-
-
0035813135
-
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor
-
Takahashi, K., et al. 2001. DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor. J. Biol. Chem. 276:37556-37563.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37556-37563
-
-
Takahashi, K.1
-
68
-
-
0035430788
-
Failure of the ubiquitin-proteasome system in Parkinson's disease
-
McNaught, K.S., Olanow, C.W., Halliwell, B., Isacson, O., and Jenner, P. 2001. Failure of the ubiquitin-proteasome system in Parkinson's disease. Nat. Rev. Neurosci. 2:589-594.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 589-594
-
-
McNaught, K.S.1
Olanow, C.W.2
Halliwell, B.3
Isacson, O.4
Jenner, P.5
|