CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism

Journal of Neurochemistry

Volumn 95, Issue 4, 2005, Pages 974-986

  Silva, Robert M ^a   Ries, Vincent ^a   Oo, Tinmarla Frances ^a   Yarygina, Olga ^a   Jackson Lewis, Vernice ^a   Ryu, Elizabeth J ^a   Lu, Phoebe D ^b   Marciniak, Stefan J ^b   Ron, David ^b   Przedborski, Serge ^a   Kholodilov, Nikolai ^a   Greene, Lloyd A ^a   Burke, Robert E ^a,c  

^a Columbia University ^*  (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Apoptosis; Endoplasmic reticulum stress; Oxidative stress; Parkinson's disease; Programmed cell death; Substantia nigra

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; DOPAMINE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; NEUROTOXIN; OXIDOPAMINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOPAMINERGIC NERVE CELL; ENDOPLASMIC RETICULUM; FEMALE; GENE EXPRESSION; GENE MUTATION; IN VIVO STUDY; METABOLITE; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL ALLELE; OXIDATIVE STRESS; PARKINSON DISEASE; PARKINSONISM; PRIORITY JOURNAL; RAT; STIMULUS; SUBSTANTIA NIGRA; TISSUE CULTURE;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; AXOTOMY; BEHAVIOR, ANIMAL; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL COUNT; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DOPAMINE; FEMALE; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; NEURONS; NEUROTOXINS; OXIDOPAMINE; PARKINSONIAN DISORDERS; PREGNANCY; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUBSTANTIA NIGRA; TIME FACTORS; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; TYROSINE 3-MONOOXYGENASE;

ANIMALIA;

EID: 28244466782     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03428.x     Document Type: Article

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