Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila

Human Molecular Genetics

Volumn 19, Issue 19, 2010, Pages 3747-3758

  Kanao, Tomoko ^a   Venderova, Katerina ^b   Park, David S ^b   Unterman, Terry ^c   Lu, Bingwei ^d,e   Imai, Yuzuru ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF ILLINOIS   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DROSOPHILA PROTEIN; LEUCINE RICH REPEAT KINASE 2; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FOXO;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DROSOPHILA; FEMALE; GENE ACTIVATION; HUMAN; LIFESPAN; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE; CELL SURVIVAL; DOPAMINE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EYE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; LONGEVITY; MEMBRANE PROTEINS; MITOSIS; MOLECULAR SEQUENCE DATA; NERVE DEGENERATION; NEURONS; NEUROPEPTIDES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION, GENETIC;

EID: 77956521263     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq289     Document Type: Article

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