The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis

Human Molecular Genetics

Volumn 14, Issue 9, 2005, Pages 1231-1241

  Xu, Jin ^a,b   Zhong, Nan ^a   Wang, Haoyong ^a   Elias, Joshua E ^c   Kim, Christina Y ^a   Woldman, Irina ^d   Pifl, Christian ^d   Gygi, Steven P ^c   Geula, Changiz ^c   Yankner, Bruce A ^b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Medical University of Vienna   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; BINDING PROTEIN; DJ 1 PROTEIN; GENE PRODUCT; MUTANT PROTEIN; NUCLEAR PROTEIN; PROTEIN P54NRB; PYRIMIDINE TRACT BINDING PROTEIN ASSOCIATED SPLICING FACTOR; REGULATOR PROTEIN; REPRESSOR PROTEIN; RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOSOMAL RECESSIVE INHERITANCE; CONTROLLED STUDY; DJ 1 GENE; DOPAMINERGIC NERVE CELL; GENE; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; NERVE CELL NECROSIS; NEUROPROTECTION; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; WILD TYPE;

ALPHA-SYNUCLEIN; APOPTOSIS; GENES, RECESSIVE; GENES, REPORTER; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUTATION; NERVE TISSUE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; NUCLEAR MATRIX-ASSOCIATED PROTEINS; OCTAMER TRANSCRIPTION FACTORS; ONCOGENE PROTEINS; OXIDATIVE STRESS; PARKINSON DISEASE; PHOSPHOPROTEINS; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; SYNUCLEINS; TRANS-ACTIVATORS; TRANSFECTION;

EID: 20944437573     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddi134     Document Type: Article

References (39)

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